PubRank

Giovanni Gadda

Author PubWeight™ 41.81‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cloning of nitroalkane oxidase from Fusarium oxysporum identifies a new member of the acyl-CoA dehydrogenase superfamily. Proc Natl Acad Sci U S A 2002 1.37
2 The COMBREX project: design, methodology, and initial results. PLoS Biol 2013 1.24
3 Design and application of a class of sensors to monitor Ca2+ dynamics in high Ca2+ concentration cellular compartments. Proc Natl Acad Sci U S A 2011 1.20
4 Developing sensors for real-time measurement of high Ca2+ concentrations. Biochemistry 2007 1.14
5 On the catalytic role of the conserved active site residue His466 of choline oxidase. Biochemistry 2005 1.07
6 Crystallographic, spectroscopic, and computational analysis of a flavin C4a-oxygen adduct in choline oxidase. Biochemistry 2009 1.04
7 Role of Glu312 in binding and positioning of the substrate for the hydride transfer reaction in choline oxidase. Biochemistry 2007 1.01
8 On the catalytic mechanism of choline oxidase. J Am Chem Soc 2005 1.00
9 Oxygen- and temperature-dependent kinetic isotope effects in choline oxidase: correlating reversible hydride transfer with environmentally enhanced tunneling. J Am Chem Soc 2005 0.96
10 Effects of reversing the protein positive charge in the proximity of the flavin N(1) locus of choline oxidase. Biochemistry 2006 0.94
11 An internal equilibrium preorganizes the enzyme-substrate complex for hydride tunneling in choline oxidase. Biochemistry 2007 0.90
12 Spectroscopic and kinetic properties of recombinant choline oxidase from Arthrobacter globiformis. Biochemistry 2003 0.90
13 Cloning, sequence analysis, and purification of choline oxidase from Arthrobacter globiformis: a bacterial enzyme involved in osmotic stress tolerance. Arch Biochem Biophys 2004 0.89
14 Involvement of a flavosemiquinone in the enzymatic oxidation of nitroalkanes catalyzed by 2-nitropropane dioxygenase. J Biol Chem 2004 0.88
15 The biochemistry of the metabolic poison propionate 3-nitronate and its conjugate acid, 3-nitropropionate. IUBMB Life 2013 0.88
16 Stabilization of an intermediate in the oxidative half-reaction of human liver glycolate oxidase. Biochemistry 2010 0.88
17 Designing protease sensors for real-time imaging of trypsin activation in pancreatic cancer cells. Biochemistry 2009 0.87
18 The chemistry of escapin: identification and quantification of the components in the complex mixture generated by an L-amino acid oxidase in the defensive secretion of the sea snail Aplysia californica. Chemistry 2009 0.87
19 Role of valine 464 in the flavin oxidation reaction catalyzed by choline oxidase. Biochemistry 2010 0.87
20 Evidence for a transient peroxynitro acid in the reaction catalyzed by nitronate monooxygenase with propionate 3-nitronate. Biochemistry 2013 0.86
21 Effect of salt and pH on the reductive half-reaction of Mycobacterium tuberculosis FprA with NADPH. Biochemistry 2008 0.84
22 Mechanistic studies of choline oxidase with betaine aldehyde and its isosteric analogue 3,3-dimethylbutyraldehyde. Biochemistry 2006 0.84
23 Insights on the mechanism of amine oxidation catalyzed by D-arginine dehydrogenase through pH and kinetic isotope effects. J Am Chem Soc 2011 0.83
24 Probing the chemical steps of nitroalkane oxidation catalyzed by 2-nitropropane dioxygenase with solvent viscosity, pH, and substrate kinetic isotope effects. Biochemistry 2006 0.83
25 Role of asparagine 510 in the relative timing of substrate bond cleavages in the reaction catalyzed by choline oxidase. Biochemistry 2010 0.82
26 Structural and kinetic studies on the Ser101Ala variant of choline oxidase: catalysis by compromise. Arch Biochem Biophys 2010 0.82
27 A pH switch affects the steady-state kinetic mechanism of pyranose 2-oxidase from Trametes ochracea. Arch Biochem Biophys 2008 0.82
28 Conformational changes and substrate recognition in Pseudomonas aeruginosa D-arginine dehydrogenase. Biochemistry 2010 0.81
29 A novel activity for fungal nitronate monooxygenase: detoxification of the metabolic inhibitor propionate-3-nitronate. Arch Biochem Biophys 2012 0.81
30 Effect of a conservative mutation of an active site residue involved in substrate binding on the hydride tunneling reaction catalyzed by choline oxidase. Arch Biochem Biophys 2009 0.81
31 Atomic-resolution structure of an N5 flavin adduct in D-arginine dehydrogenase. Biochemistry 2011 0.81
32 Oxidation of alkyl nitronates catalyzed by 2-nitropropane dioxygenase from Hansenula mrakii. Arch Biochem Biophys 2008 0.80
33 Kinetics of heme transfer by the Shr NEAT domains of Group A Streptococcus. Arch Biochem Biophys 2013 0.80
34 Involvement of ionizable groups in catalysis of human liver glycolate oxidase. J Biol Chem 2009 0.79
35 Steady-state kinetic mechanism and reductive half-reaction of D-arginine dehydrogenase from Pseudomonas aeruginosa. Biochemistry 2010 0.79
36 On the role of histidine 351 in the reaction of alcohol oxidation catalyzed by choline oxidase. Biochemistry 2008 0.79
37 Importance of a serine proximal to the C(4a) and N(5) flavin atoms for hydride transfer in choline oxidase. Biochemistry 2011 0.78
38 Human choline dehydrogenase: medical promises and biochemical challenges. Arch Biochem Biophys 2013 0.78
39 Contribution of flavin covalent linkage with histidine 99 to the reaction catalyzed by choline oxidase. J Biol Chem 2009 0.78
40 The cluster of hydrophobic residues controls the entrance to the active site of choline oxidase. Biochemistry 2009 0.77
41 Kinetic evidence for an anion binding pocket in the active site of nitronate monooxygenase. Bioorg Chem 2009 0.77
42 Pathway of glycine betaine biosynthesis in Aspergillus fumigatus. Eukaryot Cell 2013 0.77
43 The nonoxidative conversion of nitroethane to ethylnitronate in Neurospora crassa 2-nitropropane dioxygenase is catalyzed by histidine 196. Biochemistry 2008 0.77
44 Rescuing of the hydride transfer reaction in the Glu312Asp variant of choline oxidase by a substrate analogue. Arch Biochem Biophys 2010 0.76
45 Substitution of an active site valine uncovers a kinetically slow equilibrium between competent and incompetent forms of choline oxidase. Biochemistry 2008 0.76
46 Alcohol oxidation by flavoenzymes. Biomol Concepts 2014 0.76
47 Identification of the catalytic base for alcohol activation in choline oxidase. Biochemistry 2014 0.76
48 Inflated kinetic isotope effects in the branched mechanism of Neurospora crassa 2-nitropropane dioxygenase. Biochemistry 2009 0.76
49 Relative timing of hydrogen and proton transfers in the reaction of flavin oxidation catalyzed by choline oxidase. Biochemistry 2013 0.76
50 Guest editor's introduction. Special issue on oxidative enzymes. Arch Biochem Biophys 2010 0.75
51 Mechanistic and computational studies of the reductive half-reaction of tyrosine to phenylalanine active site variants of D-arginine dehydrogenase. Biochemistry 2014 0.75
52 Trapping choline oxidase in a nonfunctional conformation by freezing at low pH. Proteins 2007 0.75
53 A Reversible, Charge-Induced Intramolecular C4a-S-Cysteinyl-Flavin in Choline Oxidase Variant S101C. Biochemistry 2017 0.75
54 Enzyme Mediated Conversion of FAD to 8-formyl FAD in Formate Oxidase Results in Modified Cofactor with Enhanced Catalytic Properties. Biochemistry 2017 0.75