Published in Int J Bioinform Res Appl on January 01, 2009
Improving gene annotation using peptide mass spectrometry. Genome Res (2006) 2.69
Manipulation of carrier proteins in antibiotic biosynthesis. Chem Biol (2004) 2.46
Mechanism-based protein cross-linking probes to investigate carrier protein-mediated biosynthesis. ACS Chem Biol (2006) 2.13
Bacillithiol is an antioxidant thiol produced in Bacilli. Nat Chem Biol (2009) 2.00
Imaging mass spectrometry of intraspecies metabolic exchange revealed the cannibalistic factors of Bacillus subtilis. Proc Natl Acad Sci U S A (2010) 1.90
Ammosamides A and B target myosin. Angew Chem Int Ed Engl (2009) 1.74
The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis. Chem Biol (2012) 1.53
Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification. J Am Chem Soc (2006) 1.49
Probing the selectivity and protein·protein interactions of a nonreducing fungal polyketide synthase using mechanism-based crosslinkers. Chem Biol (2013) 1.47
The ubiquitous carrier protein--a window to metabolite biosynthesis. Nat Prod Rep (2007) 1.44
Conversion of L-proline to pyrrolyl-2-carboxyl-S-PCP during undecylprodigiosin and pyoluteorin biosynthesis. Chem Biol (2002) 1.44
One-pot chemo-enzymatic synthesis of reporter-modified proteins. Org Biomol Chem (2005) 1.41
Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula. Proc Natl Acad Sci U S A (2011) 1.40
In vivo reporter labeling of proteins via metabolic delivery of coenzyme A analogues. J Am Chem Soc (2005) 1.40
Biomimetic synthesis and optimization of cyclic peptide antibiotics. Nature (2002) 1.39
Interpretation of tandem mass spectra obtained from cyclic nonribosomal peptides. Anal Chem (2009) 1.37
Synergistic allelochemicals from a freshwater cyanobacterium. Proc Natl Acad Sci U S A (2010) 1.33
The chemical biology of modular biosynthetic enzymes. Chem Soc Rev (2009) 1.32
The phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for life. Nat Prod Rep (2014) 1.32
Marinopyrrole A target elucidation by acyl dye transfer. J Am Chem Soc (2009) 1.26
Explorations of catalytic domains in non-ribosomal peptide synthetase enzymology. Nat Prod Rep (2012) 1.23
A central strategy for converting natural products into fluorescent probes. Chembiochem (2006) 1.21
Selectfluor: mechanistic insight and applications. Angew Chem Int Ed Engl (2004) 1.20
Site-specific protein modification: advances and applications. Curr Opin Chem Biol (2006) 1.12
An orthogonal active site identification system (OASIS) for proteomic profiling of natural product biosynthesis. ACS Chem Biol (2009) 1.11
Chemical and Chemoenzymatic syntheses of bacillithiol: a unique low-molecular-weight thiol amongst low G + C Gram-positive bacteria. Angew Chem Int Ed Engl (2011) 1.10
Smoke-derived karrikin perception by the α/β-hydrolase KAI2 from Arabidopsis. Proc Natl Acad Sci U S A (2013) 1.09
Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae. Microb Cell Fact (2011) 1.08
Comment on "Protein sequences from mastodon and Tyrannosaurus rex revealed by mass spectrometry". Science (2008) 1.08
Mechanism based protein crosslinking of domains from the 6-deoxyerythronolide B synthase. Bioorg Med Chem Lett (2008) 1.02
Dehydratase-specific probes for fatty acid and polyketide synthases. J Am Chem Soc (2011) 1.02
Manipulating fatty acid biosynthesis in microalgae for biofuel through protein-protein interactions. PLoS One (2012) 1.01
A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase. Mol Biosyst (2009) 1.00
Crosslinking studies of protein-protein interactions in nonribosomal peptide biosynthesis. Chem Biol (2009) 1.00
Binding and "pKa" modulation of a polycyclic substrate analogue in a type II polyketide acyl carrier protein. ACS Chem Biol (2011) 1.00
An optimized immunoaffinity fluorescent method for natural product target elucidation. J Nat Prod (2010) 0.99
Conservation of progesterone hormone function in invertebrate reproduction. Proc Natl Acad Sci U S A (2010) 0.99
In vivo modification of native carrier protein domains. Chembiochem (2009) 0.99
Fluorescent profiling of modular biosynthetic enzymes by complementary metabolic and activity based probes. J Am Chem Soc (2008) 0.98
Engineering fatty acid biosynthesis in microalgae for sustainable biodiesel. Curr Opin Chem Biol (2013) 0.97
Carrier protein recognition in siderophore-producing nonribosomal peptide synthetases. Biochemistry (2002) 0.96
Isolation, structure elucidation, and antitumor activity of spirohexenolides A and B. J Org Chem (2009) 0.96
Modular synthesis of pantetheine and phosphopantetheine. Org Lett (2004) 0.95
Mechanism-based crosslinking as a gauge for functional interaction of modular synthases. Org Biomol Chem (2010) 0.95
Probing the compatibility of type II ketosynthase-carrier protein partners. Chembiochem (2008) 0.94
Reversible labeling of native and fusion-protein motifs. Nat Methods (2012) 0.94
Antibiotic evaluation and in vivo analysis of alkynyl Coenzyme A antimetabolites in Escherichia coli. Bioorg Med Chem Lett (2008) 0.94
A mechanism based protein crosslinker for acyl carrier protein dehydratases. Bioorg Med Chem Lett (2010) 0.93
Identification of the binding of sceptrin to MreB via a bidirectional affinity protocol. J Am Chem Soc (2008) 0.93
A synthetic entry to pladienolide B and FD-895. Bioorg Med Chem Lett (2007) 0.92
An orthogonal purification strategy for isolating crosslinked domains of modular synthases. Bioorg Med Chem Lett (2008) 0.92
Chemical defense in ascidians of the didemnidae family. Bioconjug Chem (2003) 0.92
Sulfonyl 3-alkynyl pantetheinamides as mechanism-based cross-linkers of acyl carrier protein dehydratase. J Am Chem Soc (2013) 0.90
Synthesis of the mycolactone core by ring-closing metathesis. Chem Commun (Camb) (2006) 0.90
A homogeneous resonance energy transfer assay for phosphopantetheinyl transferase. Anal Biochem (2009) 0.90
Bromophycolide A targets heme crystallization in the human malaria parasite Plasmodium falciparum. ChemMedChem (2011) 0.88
Visualizing the chain-flipping mechanism in fatty-acid biosynthesis. Angew Chem Int Ed Engl (2014) 0.87
Phosphopantetheinyl transferase inhibition and secondary metabolism. FEBS J (2009) 0.86
Preparation of FRET reporters to support chemical probe development. Org Biomol Chem (2010) 0.86
Structure of FD-895 revealed through total synthesis. Org Lett (2012) 0.86
Phorboxazole analogues induce association of cdk4 with extranuclear cytokeratin intermediate filaments. J Am Chem Soc (2006) 0.86
Napyradiomycins CNQ525.510B and A80915C target the Hsp90 paralogue Grp94. Org Biomol Chem (2013) 0.86
Functional chromatography reveals three natural products that target the same protein with distinct mechanisms of action. Chembiochem (2014) 0.85
Stabilized cyclopropane analogs of the splicing inhibitor FD-895. J Med Chem (2013) 0.84
Synthetic studies on the mycolactone core. Org Biomol Chem (2010) 0.83
The position of a key tyrosine in dTDP-4-Keto-6-deoxy-D-glucose-5-epimerase (EvaD) alters the substrate profile for this RmlC-like enzyme. J Biol Chem (2004) 0.83
Practical 4'-phosphopantetheine active site discovery from proteomic samples. J Proteome Res (2010) 0.83
The determinants of activity and specificity in actinorhodin type II polyketide ketoreductase. Chem Biol (2013) 0.83
Spirohexenolide A targets human macrophage migration inhibitory factor (hMIF). J Nat Prod (2013) 0.83
Modeling linear and cyclic PKS intermediates through atom replacement. J Am Chem Soc (2014) 0.83
Fluorescent profiling of natural product producers. J Am Chem Soc (2005) 0.82
Metabolic probes for imaging endosymbiotic bacteria within toxic dinoflagellates. Chem Commun (Camb) (2010) 0.82
The unusual macrocycle forming thioesterase of mycolactone. Mol Biosyst (2008) 0.82
Fatty acid biosynthesis revisited: structure elucidation and metabolic engineering. Mol Biosyst (2014) 0.82
A tandem chemoenzymatic methylation by S-adenosyl-L-methionine. Chembiochem (2013) 0.82
Metabolite induction of Caenorhabditis elegans dauer larvae arises via transport in the pharynx. ACS Chem Biol (2008) 0.82
Novel inositol catabolic pathway in Thermotoga maritima. Environ Microbiol (2013) 0.81
Proteomic analysis of polyketide and nonribosomal peptide biosynthesis. Curr Opin Chem Biol (2010) 0.81
Chemoenzymatic synthesis and in situ application of S-adenosyl-L-methionine analogs. Org Biomol Chem (2013) 0.81
Confluence of structural and chemical biology: plant polyketide synthases as biocatalysts for a bio-based future. Curr Opin Plant Biol (2013) 0.81
Palyosulfonoceramides A and B: unique sulfonylated ceramides from the Brazilian zoanthids Palythoa caribaeorum and Protopalythoa variabilis. Mar Drugs (2012) 0.80
Fluorescent multiplex analysis of carrier protein post-translational modification. Chembiochem (2005) 0.79
Chapter 9. Synthetic probes for polyketide and nonribosomal peptide biosynthetic enzymes. Methods Enzymol (2009) 0.79
Convergent route to the spirohexenolide macrocycle. Org Lett (2010) 0.79