Published in PLoS Pathog on September 25, 2009
HIV-1 assembly, budding, and maturation. Cold Spring Harb Perspect Med (2012) 3.17
HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation. J Mol Biol (2011) 2.01
Virus cell-to-cell transmission. J Virol (2010) 1.84
Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection. Science (2015) 1.65
3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells. Proc Natl Acad Sci U S A (2010) 1.52
Are T cells the only HIV-1 reservoir? Retrovirology (2016) 1.39
Correlative 3D imaging of whole mammalian cells with light and electron microscopy. J Struct Biol (2011) 1.33
The origins and evolution of freeze-etch electron microscopy. J Electron Microsc (Tokyo) (2011) 1.27
Cell-to-Cell Spread of Retroviruses. Viruses (2010) 1.27
Molecular determinants that regulate plasma membrane association of HIV-1 Gag. J Mol Biol (2011) 1.22
HIV-1 assembly in macrophages. Retrovirology (2010) 1.20
Macrophage internal HIV-1 is protected from neutralizing antibodies. J Virol (2011) 1.19
New insights into HIV assembly and trafficking. Physiology (Bethesda) (2011) 1.18
Relationships between plasma membrane microdomains and HIV-1 assembly. Biol Cell (2010) 1.16
High-multiplicity HIV-1 infection and neutralizing antibody evasion mediated by the macrophage-T cell virological synapse. J Virol (2013) 1.15
The role of structural bioinformatics resources in the era of integrative structural biology. Acta Crystallogr D Biol Crystallogr (2013) 1.15
A 3D cellular context for the macromolecular world. Nat Struct Mol Biol (2014) 1.12
Virus-producing cells determine the host protein profiles of HIV-1 virion cores. Retrovirology (2012) 1.04
Viral determinants of HIV-1 macrophage tropism. Viruses (2011) 1.03
Pathways of cell-cell transmission of HTLV-1. Front Microbiol (2012) 1.02
Nature, nurture and HIV: The effect of producer cell on viral physiology. Virology (2013) 1.02
3D structure determination of native mammalian cells using cryo-FIB and cryo-electron tomography. J Struct Biol (2012) 1.01
HIV-1 Virological Synapse: Live Imaging of Transmission. Viruses (2010) 1.01
Mechanisms for Env glycoprotein acquisition by retroviruses. AIDS Res Hum Retroviruses (2011) 1.01
HIV-1 activates Cdc42 and induces membrane extensions in immature dendritic cells to facilitate cell-to-cell virus propagation. Blood (2011) 1.01
Tetherin/BST-2 is essential for the formation of the intracellular virus-containing compartment in HIV-infected macrophages. Cell Host Microbe (2012) 1.00
Architecture and regulation of the HIV-1 assembly and holding compartment in macrophages. J Virol (2011) 1.00
The intracellular virus-containing compartments in primary human macrophages are largely inaccessible to antibodies and small molecules. PLoS One (2012) 0.96
3D reconstruction of VZV infected cell nuclei and PML nuclear cages by serial section array scanning electron microscopy and electron tomography. PLoS Pathog (2012) 0.96
Dynamics of HIV-containing compartments in macrophages reveal sequestration of virions and transient surface connections. PLoS One (2013) 0.94
Three-dimensional imaging of HIV-1 virological synapses reveals membrane architectures involved in virus transmission. J Virol (2014) 0.92
A cool hybrid approach to the herpesvirus 'life' cycle. Curr Opin Virol (2014) 0.92
CD36-specific antibodies block release of HIV-1 from infected primary macrophages and its transmission to T cells. J Exp Med (2013) 0.90
Organization and regulation of intracellular plasma membrane-connected HIV-1 assembly compartments in macrophages. BMC Biol (2013) 0.89
Dendritic Cells and HIV-1 Trans-Infection. Viruses (2010) 0.88
How HIV-1 takes advantage of the cytoskeleton during replication and cell-to-cell transmission. Viruses (2011) 0.88
Electron tomography of HIV-1 infection in gut-associated lymphoid tissue. PLoS Pathog (2014) 0.88
The effect of particle agglomeration on the formation of a surface-connected compartment induced by hydroxyapatite nanoparticles in human monocyte-derived macrophages. Biomaterials (2013) 0.87
Glycosphingolipid-functionalized nanoparticles recapitulate CD169-dependent HIV-1 uptake and trafficking in dendritic cells. Nat Commun (2014) 0.87
Visualizing the 3D architecture of multiple erythrocytes infected with Plasmodium at nanoscale by focused ion beam-scanning electron microscopy. PLoS One (2012) 0.86
Ion-abrasion scanning electron microscopy reveals distorted liver mitochondrial morphology in murine methylmalonic acidemia. J Struct Biol (2010) 0.85
Roles played by acidic lipids in HIV-1 Gag membrane binding. Virus Res (2014) 0.85
Dynamic Association between HIV-1 Gag and Membrane Domains. Mol Biol Int (2012) 0.84
Quantitative analysis of mouse pancreatic islet architecture by serial block-face SEM. J Struct Biol (2014) 0.84
Rab27a controls HIV-1 assembly by regulating plasma membrane levels of phosphatidylinositol 4,5-bisphosphate. J Cell Biol (2015) 0.83
Virus particle release from glycosphingolipid-enriched microdomains is essential for dendritic cell-mediated capture and transfer of HIV-1 and henipavirus. J Virol (2014) 0.83
Intravital microscopy in BLT-humanized mice to study cellular dynamics in HIV infection. J Infect Dis (2013) 0.83
Catching HIV 'in the act' with 3D electron microscopy. Trends Microbiol (2013) 0.82
Focused ion beams in biology. Nat Methods (2015) 0.81
Role of Gag and lipids during HIV-1 assembly in CD4(+) T cells and macrophages. Front Microbiol (2014) 0.81
The HIV-1 matrix protein does not interact directly with the protein interactive domain of AP-3δ. Virus Res (2012) 0.81
Visualization of ATP synthase dimers in mitochondria by electron cryo-tomography. J Vis Exp (2014) 0.80
Retroviral env glycoprotein trafficking and incorporation into virions. Mol Biol Int (2012) 0.80
Surface apposition and multiple cell contacts promote myoblast fusion in Drosophila flight muscles. J Cell Biol (2015) 0.79
Placental Hofbauer cells assemble and sequester HIV-1 in tetraspanin-positive compartments that are accessible to broadly neutralizing antibodies. J Int AIDS Soc (2015) 0.78
The intracellular plasma membrane-connected compartment in the assembly of HIV-1 in human macrophages. BMC Biol (2016) 0.78
Viral Infection at High Magnification: 3D Electron Microscopy Methods to Analyze the Architecture of Infected Cells. Viruses (2015) 0.78
A rapid label-free method for quantitation of human immunodeficiency virus type-1 particles by nanospectroscopy. J Virol Methods (2012) 0.77
Major histocompatibility complex class-II molecules promote targeting of human immunodeficiency virus type 1 virions in late endosomes by enhancing internalization of nascent particles from the plasma membrane. Cell Microbiol (2012) 0.77
Combining quantitative 2D and 3D image analysis in the serial block face SEM: application to secretory organelles of pancreatic islet cells. J Microsc (2015) 0.77
Seeing a Mycobacterium-Infected Cell in Nanoscale 3D: Correlative Imaging by Light Microscopy and FIB/SEM Tomography. PLoS One (2015) 0.76
Preservation of protein fluorescence in embedded human dendritic cells for targeted 3D light and electron microscopy. J Microsc (2015) 0.75
Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1. PLoS Pathog (2017) 0.75
Molecular Determinants Directing HIV-1 Gag Assembly to Virus-Containing Compartments in Primary Macrophages. J Virol (2016) 0.75
Viruses exploit the tissue physiology of the host to spread in vivo. Curr Opin Cell Biol (2016) 0.75
Where in the Cell Are You? Probing HIV-1 Host Interactions through Advanced Imaging Techniques. Viruses (2016) 0.75
Visualization of HIV T cell virological synapses and virus-containing compartments by 3D correlative light and electron microscopy. J Virol (2016) 0.75
Computer visualization of three-dimensional image data using IMOD. J Struct Biol (1996) 25.42
Dual-axis tomography: an approach with alignment methods that preserve resolution. J Struct Biol (1997) 6.71
Generation of high curvature membranes mediated by direct endophilin bilayer interactions. J Cell Biol (2001) 5.37
Generation of high-titer pseudotyped retroviral vectors with very broad host range. Methods Cell Biol (1994) 5.17
Infectious HIV-1 assembles in late endosomes in primary macrophages. J Cell Biol (2003) 4.68
Plasma membrane is the site of productive HIV-1 particle assembly. PLoS Biol (2006) 4.43
Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane. Nature (2002) 3.21
A mutation in the human immunodeficiency virus type 1 transmembrane glycoprotein gp41 dominantly interferes with fusion and infectivity. Proc Natl Acad Sci U S A (1992) 3.01
Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1 infections of humans. Proc Natl Acad Sci U S A (2001) 2.96
In macrophages, HIV-1 assembles into an intracellular plasma membrane domain containing the tetraspanins CD81, CD9, and CD53. J Cell Biol (2007) 2.68
HIV-1 buds predominantly at the plasma membrane of primary human macrophages. PLoS Pathog (2007) 2.44
Real-time visualization of HIV-1 GAG trafficking in infected macrophages. PLoS Pathog (2008) 2.32
Rapid and efficient cell-to-cell transmission of human immunodeficiency virus infection from monocyte-derived macrophages to peripheral blood lymphocytes. Virology (1999) 2.27
Macrophages archive HIV-1 virions for dissemination in trans. EMBO J (2005) 2.27
Replication of human immunodeficiency virus type 1 in primary dendritic cell cultures. Proc Natl Acad Sci U S A (1991) 2.25
Site-specific 3D imaging of cells and tissues with a dual beam microscope. J Struct Biol (2006) 1.96
Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells. J Cell Biol (2001) 1.87
Influence of aldehyde fixation on the morphology of endosomes and lysosomes: quantitative analysis and electron tomography. J Microsc (2003) 1.59
Long-term survival and virus production in human primary macrophages infected by human immunodeficiency virus. J Med Virol (2002) 1.49
3D imaging of mammalian cells with ion-abrasion scanning electron microscopy. J Struct Biol (2008) 1.31
Macrophage HIV-1 infection and the gastrointestinal tract reservoir. J Leukoc Biol (2003) 1.29
3D imaging of diatoms with ion-abrasion scanning electron microscopy. J Struct Biol (2009) 1.28
Evidence that productive human immunodeficiency virus type 1 assembly can occur in an intracellular compartment. J Virol (2009) 1.15
In vitro modeling of the HIV-macrophage reservoir. J Leukoc Biol (2006) 1.13
Isn't a picture still worth a thousand words? Ultrastruct Pathol (2000) 0.86
Macrophage phagocytosis of polyethylene particulate in vitro. J Biomed Mater Res (1998) 0.85
Gastric oxyntic cell structure as related to secretory activity. Histol Histopathol (1997) 0.83
Lysis of autologous human macrophages by lymphokine-activated killer cells: interaction of effector cell and target cell conjugates analyzed by scanning electron microscopy. J Leukoc Biol (1990) 0.82
Immune complex receptors on cell surfaces. III. Topography of macrophage receptors demonstrated by new scanning electron microscopic peroxidase marker. J Histochem Cytochem (1977) 0.80
Molecular architecture of native HIV-1 gp120 trimers. Nature (2008) 8.04
Nanoscale organization of multiple GPI-anchored proteins in living cell membranes. Cell (2004) 5.61
Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor. J Cell Biol (2004) 4.24
Overexpression of the N-terminal domain of TSG101 inhibits HIV-1 budding by blocking late domain function. Proc Natl Acad Sci U S A (2002) 4.14
Phosphatidylinositol (4,5) bisphosphate regulates HIV-1 Gag targeting to the plasma membrane. Proc Natl Acad Sci U S A (2004) 3.90
Retrovirus budding. Virus Res (2004) 3.66
A tubular EHD1-containing compartment involved in the recycling of major histocompatibility complex class I molecules to the plasma membrane. EMBO J (2002) 3.35
Cell-type-dependent targeting of human immunodeficiency virus type 1 assembly to the plasma membrane and the multivesicular body. J Virol (2004) 3.22
Structural mechanism of trimeric HIV-1 envelope glycoprotein activation. PLoS Pathog (2012) 3.07
Human apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (APOBEC3G) is incorporated into HIV-1 virions through interactions with viral and nonviral RNAs. J Biol Chem (2004) 3.01
High-resolution ab initio three-dimensional x-ray diffraction microscopy. J Opt Soc Am A Opt Image Sci Vis (2006) 3.00
The late domain of human immunodeficiency virus type 1 p6 promotes virus release in a cell type-dependent manner. J Virol (2002) 2.66
Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure. PLoS Pathog (2010) 2.55
Direct visualization of Escherichia coli chemotaxis receptor arrays using cryo-electron microscopy. Proc Natl Acad Sci U S A (2007) 2.51
Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures. Proc Natl Acad Sci U S A (2011) 2.38
Real-time visualization of HIV-1 GAG trafficking in infected macrophages. PLoS Pathog (2008) 2.32
Electron tomography of the contact between T cells and SIV/HIV-1: implications for viral entry. PLoS Pathog (2007) 2.14
Three-dimensional structure of a bacterial oxalate transporter. Nat Struct Biol (2002) 2.10
Beyond Tsg101: the role of Alix in 'ESCRTing' HIV-1. Nat Rev Microbiol (2007) 2.08
HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation. J Mol Biol (2011) 2.01
Site-specific 3D imaging of cells and tissues with a dual beam microscope. J Struct Biol (2006) 1.96
Human immunodeficiency virus type 1 assembly, release, and maturation. Adv Pharmacol (2007) 1.90
Role of lipid rafts in virus replication. Adv Virus Res (2005) 1.89
Regulation of human immunodeficiency virus type 1 Env-mediated membrane fusion by viral protease activity. J Virol (2004) 1.89
Electron microscopic analysis of membrane assemblies formed by the bacterial chemotaxis receptor Tsr. J Bacteriol (2003) 1.82
Prefusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy. Nat Struct Mol Biol (2013) 1.80
Defects in human immunodeficiency virus budding and endosomal sorting induced by TSG101 overexpression. J Virol (2003) 1.79
The Visible Human data sets (VHD) and Insight Toolkit (ITk): experiments in open source software. AMIA Annu Symp Proc (2003) 1.78
The structure of purified kinetochores reveals multiple microtubule-attachment sites. Nat Struct Mol Biol (2012) 1.76
A cell-penetrating helical peptide as a potential HIV-1 inhibitor. J Mol Biol (2008) 1.70
In vitro resistance to the human immunodeficiency virus type 1 maturation inhibitor PA-457 (Bevirimat). J Virol (2006) 1.70
Structural basis for viral late-domain binding to Alix. Nat Struct Mol Biol (2007) 1.69
Automated image acquisition and processing using a new generation of 4K x 4K CCD cameras for cryo electron microscopic studies of macromolecular assemblies. J Struct Biol (2003) 1.67
Late domain-dependent inhibition of equine infectious anemia virus budding. J Virol (2004) 1.57
Association of human immunodeficiency virus type 1 gag with membrane does not require highly basic sequences in the nucleocapsid: use of a novel Gag multimerization assay. J Virol (2005) 1.55
3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells. Proc Natl Acad Sci U S A (2010) 1.52
Cryo-electron tomography of bacteria: progress, challenges and future prospects. Nat Rev Microbiol (2009) 1.51
Lipids and membrane microdomains in HIV-1 replication. Virus Res (2009) 1.51
Chemoreceptors in Caulobacter crescentus: trimers of receptor dimers in a partially ordered hexagonally packed array. J Bacteriol (2008) 1.50
Determinants of activity of the HIV-1 maturation inhibitor PA-457. Virology (2006) 1.49
Cryoelectron tomographic analysis of an HIV-neutralizing protein and its complex with native viral gp120. J Biol Chem (2007) 1.48
Novel approaches to inhibiting HIV-1 replication. Antiviral Res (2009) 1.48
Three-dimensional electron microscopic imaging of membrane invaginations in Escherichia coli overproducing the chemotaxis receptor Tsr. J Bacteriol (2004) 1.45
An Alix fragment potently inhibits HIV-1 budding: characterization of binding to retroviral YPXL late domains. J Biol Chem (2006) 1.44
Design of a hyperstable 60-subunit protein icosahedron. Nature (2016) 1.42
Role of HAMP domains in chemotaxis signaling by bacterial chemoreceptors. Proc Natl Acad Sci U S A (2008) 1.40
Mesenchymal stem cells induce mature dendritic cells into a novel Jagged-2-dependent regulatory dendritic cell population. Blood (2008) 1.39
Membrane protein structure determination using cryo-electron tomography and 3D image averaging. Curr Opin Struct Biol (2009) 1.38
Point mutations in the HIV-1 matrix protein turn off the myristyl switch. J Mol Biol (2006) 1.38
Structural model for 12-helix transporters belonging to the major facilitator superfamily. J Bacteriol (2003) 1.38
Nonsense mutations in ADTB3A cause complete deficiency of the beta3A subunit of adaptor complex-3 and severe Hermansky-Pudlak syndrome type 2. Pediatr Res (2002) 1.37
A core-weighted fitting method for docking atomic structures into low-resolution maps: application to cryo-electron microscopy. J Struct Biol (2003) 1.36
Protein secondary structure determination by constrained single-particle cryo-electron tomography. Structure (2012) 1.36
Mutation of dileucine-like motifs in the human immunodeficiency virus type 1 capsid disrupts virus assembly, gag-gag interactions, gag-membrane binding, and virion maturation. J Virol (2006) 1.35
Impact of human immunodeficiency virus type 1 resistance to protease inhibitors on evolution of resistance to the maturation inhibitor bevirimat (PA-457). J Virol (2009) 1.33
Correlative 3D imaging of whole mammalian cells with light and electron microscopy. J Struct Biol (2011) 1.33
HIV-1 maturation inhibitor bevirimat stabilizes the immature Gag lattice. J Virol (2010) 1.33
3D imaging of mammalian cells with ion-abrasion scanning electron microscopy. J Struct Biol (2008) 1.31
Structure of the myristylated human immunodeficiency virus type 2 matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in membrane targeting. J Mol Biol (2008) 1.31
Molecular architecture and mechanism of an icosahedral pyruvate dehydrogenase complex: a multifunctional catalytic machine. EMBO J (2002) 1.30
Cell surface filaments of the gliding bacterium Flavobacterium johnsoniae revealed by cryo-electron tomography. J Bacteriol (2007) 1.30
Depletion of cellular cholesterol inhibits membrane binding and higher-order multimerization of human immunodeficiency virus type 1 Gag. Virology (2006) 1.30
NIH-NSF Visualization Research Challenges report summary. IEEE Comput Graph Appl (2006) 1.29
3D imaging of diatoms with ion-abrasion scanning electron microscopy. J Struct Biol (2009) 1.28
Human immunodeficiency virus type 1 N-terminal capsid mutants containing cores with abnormally high levels of capsid protein and virtually no reverse transcriptase. J Virol (2003) 1.24
Polymorphisms in Gag spacer peptide 1 confer varying levels of resistance to the HIV- 1 maturation inhibitor bevirimat. Retrovirology (2010) 1.24
A mutation in the human immunodeficiency virus type 1 Gag protein destabilizes the interaction of the envelope protein subunits gp120 and gp41. J Virol (2006) 1.22
Multifaceted roles of tunneling nanotubes in intercellular communication. Front Physiol (2012) 1.21
An energy-based three-dimensional segmentation approach for the quantitative interpretation of electron tomograms. IEEE Trans Image Process (2005) 1.20
Data management challenges in three-dimensional EM. Nat Struct Mol Biol (2012) 1.19
Distribution of ESCRT machinery at HIV assembly sites reveals virus scaffolding of ESCRT subunits. Science (2014) 1.19
HIV-1 envelope glycoprotein structure. Curr Opin Struct Biol (2013) 1.19
New insights into HIV assembly and trafficking. Physiology (Bethesda) (2011) 1.18
Three-dimensional structures of soluble CD4-bound states of trimeric simian immunodeficiency virus envelope glycoproteins determined by using cryo-electron tomography. J Virol (2011) 1.18
Glutamate receptor desensitization is mediated by changes in quaternary structure of the ligand binding domain. Proc Natl Acad Sci U S A (2013) 1.17
Structure and accessibility of HA trimers on intact 2009 H1N1 pandemic influenza virus to stem region-specific neutralizing antibodies. Proc Natl Acad Sci U S A (2013) 1.17
Functional role of Alix in HIV-1 replication. Virology (2009) 1.16