Published in J R Soc Med on October 01, 2009
Expression of HERV-Fc1, a human endogenous retrovirus, is increased in patients with active multiple sclerosis. J Virol (2012) 1.04
Detection of the human endogenous retrovirus ERV3-encoded Env-protein in human tissues using antibody-based proteomics. J R Soc Med (2013) 0.78
Human endogenous retroviruses in multiple sclerosis: potential for novel neuro-pharmacological research. Curr Neuropharmacol (2011) 0.77
Alu repeats and human genomic diversity. Nat Rev Genet (2002) 12.40
Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell (2008) 9.59
Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man. Nature (1988) 6.01
Defining the role of the MHC in autoimmunity: a review and pooled analysis. PLoS Genet (2008) 3.54
Mutation of DNASE1 in people with systemic lupus erythematosus. Nat Genet (2001) 3.21
A new retrotransposable human L1 element from the LRE2 locus on chromosome 1q produces a chimaeric insertion. Nat Genet (1994) 2.68
Human endogenous retrovirus glycoprotein-mediated induction of redox reactants causes oligodendrocyte death and demyelination. Nat Neurosci (2004) 2.64
An update of the HLA genomic region, locus information and disease associations: 2004. Tissue Antigens (2004) 2.20
Monocyte activation and differentiation augment human endogenous retrovirus expression: implications for inflammatory brain diseases. Ann Neurol (2001) 2.16
Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis. The Collaborative Research Group on Multiple Sclerosis. Proc Natl Acad Sci U S A (1997) 1.97
Insertion of a 5' truncated L1 element into the 3' end of exon 44 of the dystrophin gene resulted in skipping of the exon during splicing in a case of Duchenne muscular dystrophy. J Clin Invest (1993) 1.92
Retroviral RNA identified in the cerebrospinal fluids and brains of individuals with schizophrenia. Proc Natl Acad Sci U S A (2001) 1.82
A human endogenous retroviral superantigen as candidate autoimmune gene in type I diabetes. Cell (1997) 1.80
Genomics of the major histocompatibility complex: haplotypes, duplication, retroviruses and disease. Immunol Rev (1999) 1.65
Processed pseudogenes of human endogenous retroviruses generated by LINEs: their integration, stability, and distribution. Genome Res (2002) 1.54
Deletion of azoospermia factor a (AZFa) region of human Y chromosome caused by recombination between HERV15 proviruses. Hum Mol Genet (2000) 1.53
Brains and peripheral blood mononuclear cells of multiple sclerosis (MS) patients hyperexpress MS-associated retrovirus/HERV-W endogenous retrovirus, but not Human herpesvirus 6. J Gen Virol (2007) 1.50
Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity. Immunity (2001) 1.47
Two long homologous retroviral sequence blocks in proximal Yq11 cause AZFa microdeletions as a result of intrachromosomal recombination events. Hum Mol Genet (2000) 1.44
Symbiosis versus competition in plant virus evolution. Nat Rev Microbiol (2005) 1.41
The envelope protein of a human endogenous retrovirus-W family activates innate immunity through CD14/TLR4 and promotes Th1-like responses. J Immunol (2006) 1.39
Duplications of the AZFa region of the human Y chromosome are mediated by homologous recombination between HERVs and are compatible with male fertility. Hum Mol Genet (2003) 1.37
Human endogenous retrovirus expression profiles in samples from brains of patients with schizophrenia and bipolar disorders. J Virol (2005) 1.29
Multiple sclerosis retrovirus particles and recombinant envelope trigger an abnormal immune response in vitro, by inducing polyclonal Vbeta16 T-lymphocyte activation. Virology (2001) 1.22
Several genes in the extended human MHC contribute to predisposition to autoimmune diseases. Curr Opin Immunol (2005) 1.19
Human endogenous retrovirus (HERV)-W ENV and GAG proteins: physiological expression in human brain and pathophysiological modulation in multiple sclerosis lesions. J Neurovirol (2005) 1.19
Transactivation of elements in the human endogenous retrovirus W family by viral infection. Retrovirology (2006) 1.16
Genomic evolution of MHC class I region in primates. Proc Natl Acad Sci U S A (2005) 1.08
Novel reliable real-time PCR for differential detection of MSRVenv and syncytin-1 in RNA and DNA from patients with multiple sclerosis. J Virol Methods (2009) 1.06
Multiple sclerosis-associated retrovirus (MSRV) in Sardinian MS patients. Neurology (2002) 1.05
Endogenous retroviruses and schizophrenia. Brain Res Brain Res Rev (2000) 1.02
Perspectives on the role of endogenous human retroviruses in autoimmune diseases. Virology (2002) 1.01
Analysis of transcribed human endogenous retrovirus W env loci clarifies the origin of multiple sclerosis-associated retrovirus env sequences. Retrovirology (2009) 1.00
Multiple sclerosis-associated retrovirus particles cause T lymphocyte-dependent death with brain hemorrhage in humanized SCID mice model. J Neurovirol (2003) 0.99
Retroviral superantigens and type 1 diabetes mellitus. Cell (1998) 0.96
Inhibition of multiple-sclerosis-associated retrovirus as biomarker of interferon therapy. J Neurovirol (2008) 0.94
Development of insulin-dependent diabetes mellitus does not depend on specific expression of the human endogenous retrovirus HERV-K. Cell (1998) 0.94
Selective antibody reactivity with peptides from human endogenous retroviruses and nonviral poly(amino acids) in patients with systemic lupus erythematosus. Arthritis Rheum (1996) 0.93
The expression of human endogenous retrovirus-3 in fetal cardiac tissue and antibodies in congenital heart block. Clin Exp Immunol (1996) 0.90
Cellular localization of placenta-specific human endogenous retrovirus (HERV) transcripts and their possible implication in pregnancy-induced hypertension. Placenta (2007) 0.89
Cytokine regulation of env gene expression of human endogenous retrovirus-R in human vascular endothelial cells. Clin Immunol (1999) 0.89
Multiple sclerosis-associated virus-related pol sequences found both in multiple sclerosis and healthy donors are more frequently expressed in multiple sclerosis patients. J Neurovirol (2003) 0.88
The source of self: genetic parasites and the origin of adaptive immunity. Ann N Y Acad Sci (2009) 0.87
Haplotype sharing analysis identifies a retroviral dUTPase as candidate susceptibility gene for psoriasis. J Invest Dermatol (2005) 0.87
Insertional polymorphism of endogenous retrovirus HERV-K115 in schizophrenia. Neurosci Lett (2006) 0.87
Regulation of the syncytin-1 promoter in human astrocytes by multiple sclerosis-related cytokines. Virology (2007) 0.86
Retrovirus in salivary glands from patients with Sjögren's syndrome. J Clin Pathol (1997) 0.83
An Alu insert as the cause of a severe form of hemophilia A. Acta Haematol (2001) 0.83
An endogenous retroviral long terminal repeat at the HLA-DQB1 gene locus confers susceptibility to rheumatoid arthritis. Hum Immunol (1999) 0.82
Quantitative expression of the HERV-W env gene in human tissues. Arch Virol (2008) 0.81
An alternative approach to medical genetics based on modern evolutionary biology. Part 2: retroviral symbiosis. J R Soc Med (2009) 0.81
Systemic lupus erythematosus and human endogenous retroviruses. Mod Rheumatol (2003) 0.81
Retroviruses in autoimmune liver disease: genetic or environmental agents? Arch Immunol Ther Exp (Warsz) (1999) 0.80
Serum antibodies against human intracisternal A-type particle (HIAP) endogenous retrovirus in Alopecia areata patients: a hallmark of autoimmune disease? J Invest Dermatol (2004) 0.80