PubRank

Dieter Willbold

Author PubWeight™ 112.90‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012 20.08
2 Nix directly binds to GABARAP: a possible crosstalk between apoptosis and autophagy. Autophagy 2009 1.90
3 Integral membrane proteins in nanodiscs can be studied by solution NMR spectroscopy. J Am Chem Soc 2009 1.33
4 BEST-TROSY experiments for time-efficient sequential resonance assignment of large disordered proteins. J Biomol NMR 2013 1.32
5 Pyroglutamate formation influences solubility and amyloidogenicity of amyloid peptides. Biochemistry 2009 1.25
6 Therapeutic vaccination of HIV-1-infected patients on HAART with a recombinant HIV-1 nef-expressing MVA: safety, immunogenicity and influence on viral load during treatment interruption. Antivir Ther 2005 1.22
7 Selection of D-amino-acid peptides that bind to Alzheimer's disease amyloid peptide abeta1-42 by mirror image phage display. Chembiochem 2003 1.13
8 Structural insights into conformational changes of a cyclic nucleotide-binding domain in solution from Mesorhizobium loti K1 channel. Proc Natl Acad Sci U S A 2011 1.11
9 HIV-1 Nef mimics an integrin receptor signal that recruits the polycomb group protein Eed to the plasma membrane. Mol Cell 2004 1.07
10 Oligomer assembly of the C-terminal DISC1 domain (640-854) is controlled by self-association motifs and disease-associated polymorphism S704C. Biochemistry 2009 1.07
11 Identification of calreticulin as a ligand of GABARAP by phage display screening of a peptide library. FEBS J 2007 1.04
12 Glutamic acid-rich proteins of rod photoreceptors are natively unfolded. J Biol Chem 2005 1.04
13 Reduction of Alzheimer's disease amyloid plaque load in transgenic mice by D3, A D-enantiomeric peptide identified by mirror image phage display. ChemMedChem 2008 1.04
14 Nanodiscs allow the use of integral membrane proteins as analytes in surface plasmon resonance studies. Anal Biochem 2010 1.01
15 Solution structure of the Mesorhizobium loti K1 channel cyclic nucleotide-binding domain in complex with cAMP. EMBO Rep 2009 1.01
16 Oral treatment with the d-enantiomeric peptide D3 improves the pathology and behavior of Alzheimer's Disease transgenic mice. ACS Chem Neurosci 2010 0.98
17 Transient structure and SH3 interaction sites in an intrinsically disordered fragment of the hepatitis C virus protein NS5A. J Mol Biol 2012 0.98
18 Structural changes of membrane-anchored native PrP(C). Proc Natl Acad Sci U S A 2008 0.96
19 Helix formation in arrestin accompanies recognition of photoactivated rhodopsin. Biochemistry 2009 0.96
20 Detection of prion protein particles in blood plasma of scrapie infected sheep. PLoS One 2012 0.96
21 Double-strand DNA end-binding and sliding of the toroidal CRISPR-associated protein Csn2. Nucleic Acids Res 2013 0.95
22 c-Src is required for complex formation between the hepatitis C virus-encoded proteins NS5A and NS5B: a prerequisite for replication. Hepatology 2011 0.94
23 Identification of clathrin heavy chain as a direct interaction partner for the gamma-aminobutyric acid type A receptor associated protein. Biochemistry 2007 0.94
24 Counting of single prion particles bound to a capture-antibody surface (surface-FIDA). Vet Microbiol 2007 0.93
25 Spontaneous and BSE-prion-seeded amyloid formation of full length recombinant bovine prion protein. Biochem Biophys Res Commun 2008 0.93
26 In vitro and in vivo staining characteristics of small, fluorescent, Abeta42-binding D-enantiomeric peptides in transgenic AD mouse models. ChemMedChem 2009 0.93
27 Structural basis for the slow dark recovery of a full-length LOV protein from Pseudomonas putida. J Mol Biol 2012 0.92
28 Differently selected D-enantiomeric peptides act on different Abeta species. Rejuvenation Res 2010 0.90
29 An N-terminal amphipathic helix in dengue virus nonstructural protein 4A mediates oligomerization and is essential for replication. J Virol 2013 0.90
30 Structural framework of the GABARAP-calreticulin interface--implications for substrate binding to endoplasmic reticulum chaperones. FEBS J 2009 0.90
31 Solution structure of human GABA(A) receptor-associated protein GABARAP: implications for biolgoical funcrion and its regulation. J Biol Chem 2002 0.89
32 Probing transient conformational states of proteins by solid-state R(1ρ) relaxation-dispersion NMR spectroscopy. Angew Chem Int Ed Engl 2014 0.89
33 Single particle detection of Abeta aggregates associated with Alzheimer's disease. Biochem Biophys Res Commun 2007 0.88
34 The amyloid-β oligomer count in cerebrospinal fluid is a biomarker for Alzheimer's disease. J Alzheimers Dis 2013 0.87
35 Structural analysis of the pyroglutamate-modified isoform of the Alzheimer's disease-related amyloid-β using NMR spectroscopy. J Pept Sci 2012 0.86
36 Interaction of Bcl-2 with the autophagy-related GABAA receptor-associated protein (GABARAP): biophysical characterization and functional implications. J Biol Chem 2013 0.86
37 NMR structural characterization of HIV-1 virus protein U cytoplasmic domain in the presence of dodecylphosphatidylcholine micelles. FEBS J 2009 0.86
38 Ligand binding mode of GABAA receptor-associated protein. J Mol Biol 2008 0.86
39 Sequence-independent control of peptide conformation in liposomal vaccines for targeting protein misfolding diseases. J Biol Chem 2011 0.86
40 Single vector system for efficient N-myristoylation of recombinant proteins in E. coli. PLoS One 2010 0.85
41 Mirror image phage display--a method to generate D-peptide ligands for use in diagnostic or therapeutical applications. Mol Biosyst 2009 0.85
42 Nef protein of human immunodeficiency virus type 1 binds its own myristoylated N-terminus. Biol Chem 2007 0.85
43 Discovery and structure activity relationship of small molecule inhibitors of toxic β-amyloid-42 fibril formation. J Biol Chem 2012 0.85
44 Mirror-image phage display: aiming at the mirror. Chembiochem 2003 0.85
45 Peptides for therapy and diagnosis of Alzheimer's disease. Curr Pharm Des 2012 0.85
46 Sequestration of a β-hairpin for control of α-synuclein aggregation. Angew Chem Int Ed Engl 2014 0.84
47 Combining independent drug classes into superior, synergistically acting hybrid molecules. Angew Chem Int Ed Engl 2010 0.84
48 Modulation of aggregate size- and shape-distributions of the amyloid-beta peptide by a designed beta-sheet breaker. Eur Biophys J 2009 0.83
49 Treatment with D3 removes amyloid deposits, reduces inflammation, and improves cognition in aged AβPP/PS1 double transgenic mice. J Alzheimers Dis 2013 0.83
50 Fluorine-18 labeling of three novel D-peptides by conjugation with N-succinimidyl-4-[18F]fluorobenzoate and preliminary examination by postmortem whole-hemisphere human brain autoradiography. Nucl Med Biol 2011 0.83
51 An RTX transporter tethers its unfolded substrate during secretion via a unique N-terminal domain. Structure 2012 0.83
52 Mapping the interaction between the cytoplasmic domains of HIV-1 viral protein U and human CD4 with NMR spectroscopy. FEBS J 2012 0.83
53 Comparative modeling of human NSF reveals a possible binding mode of GABARAP and GATE-16. Proteins 2009 0.82
54 Solution structure of Atg8 reveals conformational polymorphism of the N-terminal domain. Biochem Biophys Res Commun 2010 0.82
55 Structure and potential function of gamma-aminobutyrate type A receptor-associated protein. FEBS J 2009 0.82
56 Conservation of dark recovery kinetic parameters and structural features in the pseudomonadaceae "short" light, oxygen, voltage (LOV) protein family: implications for the design of LOV-based optogenetic tools. Biochemistry 2013 0.82
57 Interaction of nonstructural protein 5A of the hepatitis C virus with Src homology 3 domains using noncanonical binding sites. Biochemistry 2013 0.82
58 Purification of recombinantly expressed and cytotoxic human amyloid-beta peptide 1-42. J Chromatogr B Analyt Technol Biomed Life Sci 2007 0.82
59 Transient reduction of spontaneous neuronal network activity by sublethal amyloid beta (1-42) peptide concentrations. J Neural Transm (Vienna) 2009 0.82
60 Seeded fibrillation as molecular basis of the species barrier in human prion diseases. PLoS One 2013 0.82
61 iHADAMAC: a complementary tool for sequential resonance assignment of globular and highly disordered proteins. J Magn Reson 2011 0.81
62 Presence of a helix in human CD4 cytoplasmic domain promotes binding to HIV-1 Nef protein. Biochem Biophys Res Commun 2002 0.81
63 Preparation of a functional GABARAP-lipid conjugate in nanodiscs and its investigation by solution NMR spectroscopy. Chembiochem 2010 0.81
64 Mirror image phage display--generating stable therapeutically and diagnostically active peptides with biotechnological means. J Biotechnol 2012 0.80
65 Competitive displacement of full-length HIV-1 Nef from the Hck SH3 domain by a high-affinity artificial peptide. Biol Chem 2007 0.80
66 Solution structure of a Hck SH3 domain ligand complex reveals novel interaction modes. J Mol Biol 2006 0.80
67 Structural studies of the phosphatidylinositol 3-kinase (PI3K) SH3 domain in complex with a peptide ligand: role of the anchor residue in ligand binding. Biol Chem 2010 0.80
68 A highly sensitive diagnostic assay for aggregate-related diseases, including prion diseases and Alzheimer's disease. Rejuvenation Res 2008 0.80
69 Transport of Alzheimer disease amyloid-beta-binding D-amino acid peptides across an in vitro blood-brain barrier model. Rejuvenation Res 2010 0.80
70 Competitively selected protein ligands pay their increase in specificity by a decrease in affinity. Mol Biosyst 2009 0.80
71 Brain transcriptome-wide screen for HIV-1 Nef protein interaction partners reveals various membrane-associated proteins. PLoS One 2012 0.80
72 Treatment with Aβ42 binding D-amino acid peptides reduce amyloid deposition and inflammation in APP/PS1 double transgenic mice. Adv Protein Chem Struct Biol 2012 0.80
73 Single-particle detection system for Abeta aggregates: adaptation of surface-fluorescence intensity distribution analysis to laser scanning microscopy. Rejuvenation Res 2010 0.80
74 The D-amino acid peptide D3 reduces amyloid fibril boosted HIV-1 infectivity. AIDS Res Ther 2014 0.79
75 Structural consequences of phosphorylation of two serine residues in the cytoplasmic domain of HIV-1 VpU. J Pept Sci 2008 0.79
76 Characterization of a single-chain variable fragment recognizing a linear epitope of aβ: a biotechnical tool for studies on Alzheimer's disease? PLoS One 2013 0.79
77 Structure of human immunodeficiency virus type 1 Vpr(34-51) peptide in micelle containing aqueous solution. Eur J Biochem 2002 0.79
78 Solution structure of the X4 protein coded by the SARS related coronavirus reveals an immunoglobulin like fold and suggests a binding activity to integrin I domains. J Biomed Sci 2005 0.79
79 The off-rate of monomers dissociating from amyloid-β protofibrils. J Biol Chem 2013 0.79
80 1H, 13C, and 15N resonance assignment of a 179 residue fragment of hepatitis C virus non-structural protein 5A. Biomol NMR Assign 2011 0.79
81 Distribution and binding of 18F-labeled and 125I-labeled analogues of ACI-80, a prospective molecular imaging biomarker of disease: a whole hemisphere post mortem autoradiography study in human brains obtained from Alzheimer's disease patients. Neurochem Int 2011 0.79
82 Insights into human Lck SH3 domain binding specificity: different binding modes of artificial and native ligands. Biochemistry 2005 0.79
83 An indole-binding site is a major determinant of the ligand specificity of the GABA type A receptor-associated protein GABARAP. Chembiochem 2008 0.79
84 Resonance assignment of the cyclic nucleotide binding domain from a cyclic nucleotide-gated K(+) channel in complex with cAMP. Biomol NMR Assign 2007 0.78
85 Mapping the binding site of full length HIV-1 Nef on human Lck SH3 by NMR spectroscopy. J Biomed Sci 2005 0.78
86 Molecular interactions between prions as seeds and recombinant prion proteins as substrates resemble the biological interspecies barrier in vitro. PLoS One 2010 0.78
87 Hepatitis C virus NS5A is able to competitively displace c-Myc from the Bin1 SH3 domain in vitro. J Pept Sci 2014 0.78
88 Progress towards structural understanding of infectious sheep PrP-amyloid. Prion 2014 0.78
89 Assessment of GABARAP self-association by its diffusion properties. J Biomol NMR 2010 0.77
90 Full-length Vpu and human CD4(372-433) in phospholipid bilayers as seen by magic angle spinning NMR. Biol Chem 2013 0.77
91 Identification and characterization of an aβ oligomer precipitating peptide that may be useful to explore gene therapeutic approaches to Alzheimer disease. Rejuvenation Res 2012 0.77
92 Resonance assignments of the nucleotide-free wildtype MloK1 cyclic nucleotide-binding domain. Biomol NMR Assign 2010 0.77
93 Relaxation behavior study of ultrasmall superparamagnetic iron oxide nanoparticles at ultralow and ultrahigh magnetic fields. J Phys Chem B 2011 0.77
94 A β-hairpin-binding protein for three different disease-related amyloidogenic proteins. Chembiochem 2014 0.77
95 Aggregation and amyloid fibril formation of the prion protein is accelerated in the presence of glycogen. Rejuvenation Res 2008 0.77
96 Structure determination of human Lck unique and SH3 domains by nuclear magnetic resonance spectroscopy. BMC Struct Biol 2003 0.77
97 NMR structure of the transmembrane and cytoplasmic domains of human CD4 in micelles. Biochim Biophys Acta 2009 0.77
98 Nanodiscs allow phage display selection for ligands to non-linear epitopes on membrane proteins. PLoS One 2013 0.76
99 Development of a small D-enantiomeric Alzheimer's amyloid-β binding peptide ligand for future in vivo imaging applications. PLoS One 2012 0.76
100 In vitro conversion and seeded fibrillization of posttranslationally modified prion protein. Biol Chem 2011 0.76
101 Structural characterization of GABARAP-ligand interactions. Mol Biosyst 2009 0.76
102 An ultrasensitive assay for diagnosis of Alzheimer's disease. Rejuvenation Res 2008 0.76
103 Structural characterization of the transmembrane and cytoplasmic domains of human CD4. Biochim Biophys Acta 2007 0.76
104 Sequence-specific 1H, 13C, and 15N resonance assignment of the autophagy-related protein Atg8. Biomol NMR Assign 2009 0.75
105 Insights into the mechanism of ligand binding to octopine dehydrogenase from Pecten maximus by NMR and crystallography. PLoS One 2010 0.75
106 Correction: Competitive Mirror Image Phage Display Derived Peptide Modulates Amyloid Beta Aggregation and Toxicity. PLoS One 2016 0.75
107 Crystallization and preliminary X-ray crystallographic studies of an oligomeric species of a refolded C39 peptidase-like domain of the Escherichia coli ABC transporter haemolysin B. Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 0.75
108 A synthetic amino acid substitution of Tyr10 in Aβ peptide sequence yields a dominant negative variant in amyloidogenesis. Aging Cell 2012 0.75
109 Assembling an ion channel: ORF 3a from SARS-CoV. Biopolymers 2013 0.75
110 SARS-CoV accessory protein 7a directly interacts with human LFA-1. Biol Chem 2007 0.75
111 1H, 15N and 13C resonance assignment of the N-terminal C39 peptidase-like domain of the ABC transporter Haemolysin B (HlyB). Biomol NMR Assign 2011 0.75
112 The effect of neurosphere culture conditions on the cellular metabolism of glioma cells. Folia Neuropathol 2015 0.75
113 Purification of recombinantly expressed human cluster determinant 4 cytoplasmic domain. J Chromatogr B Analyt Technol Biomed Life Sci 2003 0.75
114 Highlight: NRW Research School BioStruct--biological structures in molecular medicine and biotechnology. Biol Chem 2013 0.75
115 Nonaqueous versus aqueous capillary electrophoresis of alpha-helical polypeptides: effect of secondary structure on separation selectivity. Electrophoresis 2006 0.75
116 Expression, purification, and membrane reconstitution of a CD4 fragment comprising the transmembrane and cytoplasmic domains of the receptor. Protein Expr Purif 2007 0.75
117 Binding of TCA to the prion protein: mechanism, implication for therapy, and application as probe for complex formation of bio-macromolecules. J Biomol Struct Dyn 2009 0.75
118 Analysis of anticoagulants for blood-based quantitation of amyloid β oligomers in the sFIDA assay. Biol Chem 2016 0.75
119 Electrochemical dual-aptamer biosensors based on nanostructured multielectrode arrays for the detection of neuronal biomarkers. Nanoscale 2020 0.75