|
1
|
Endothelial dysfunction in small arteries of essential hypertensive patients: role of cyclooxygenase-2 in oxidative stress generation.
|
Hypertension
|
2013
|
2.82
|
|
2
|
Cholinergic toxic syndrome by the anticancer drug irinotecan: acetylcholinesterase does not play a major role.
|
Clin Pharmacol Ther
|
2002
|
1.39
|
|
3
|
Regulation of enteric functions by adenosine: pathophysiological and pharmacological implications.
|
Pharmacol Ther
|
2008
|
1.19
|
|
4
|
Vascular generation of tumor necrosis factor-α reduces nitric oxide availability in small arteries from visceral fat of obese patients.
|
J Am Coll Cardiol
|
2011
|
1.16
|
|
5
|
Safety concerns associated with the use of serotonin reuptake inhibitors and other serotonergic/noradrenergic antidepressants during pregnancy: a review.
|
Clin Ther
|
2009
|
1.15
|
|
6
|
Immunohistochemical analysis of myenteric ganglia and interstitial cells of Cajal in ulcerative colitis.
|
J Cell Mol Med
|
2012
|
1.04
|
|
7
|
Platelet serotonin transporter in patients with diarrhea-predominant irritable bowel syndrome both before and after treatment with alosetron.
|
Am J Gastroenterol
|
2003
|
1.04
|
|
8
|
Cyclooxygenase-1 is involved in endothelial dysfunction of mesenteric small arteries from angiotensin II-infused mice.
|
Hypertension
|
2006
|
1.02
|
|
9
|
Inhibition of adenosine deaminase attenuates inflammation in experimental colitis.
|
J Pharmacol Exp Ther
|
2007
|
1.01
|
|
10
|
Adenosine deaminase in the modulation of immune system and its potential as a novel target for treatment of inflammatory disorders.
|
Curr Drug Targets
|
2012
|
1.01
|
|
11
|
Altered prejunctional modulation of intestinal cholinergic and noradrenergic pathways by alpha2-adrenoceptors in the presence of experimental colitis.
|
Br J Pharmacol
|
2003
|
1.01
|
|
12
|
Role of coxibs in the strategies for gastrointestinal protection in patients requiring chronic non-steroidal anti-inflammatory therapy.
|
Pharmacol Res
|
2008
|
0.99
|
|
13
|
Atorvastatin prevents endothelial dysfunction in mesenteric arteries from spontaneously hypertensive rats: role of cyclooxygenase 2-derived contracting prostanoids.
|
Hypertension
|
2009
|
0.96
|
|
14
|
Lansoprazole prevents experimental gastric injury induced by non-steroidal anti-inflammatory drugs through a reduction of mucosal oxidative damage.
|
World J Gastroenterol
|
2005
|
0.96
|
|
15
|
Differential recruitment of high affinity A1 and A2A adenosine receptors in the control of colonic neuromuscular function in experimental colitis.
|
Eur J Pharmacol
|
2010
|
0.96
|
|
16
|
Pharmacological modulation of adenosine system: novel options for treatment of inflammatory bowel diseases.
|
Inflamm Bowel Dis
|
2008
|
0.94
|
|
17
|
The blockade of adenosine deaminase ameliorates chronic experimental colitis through the recruitment of adenosine A2A and A3 receptors.
|
J Pharmacol Exp Ther
|
2010
|
0.93
|
|
18
|
Mechanisms of gastroprotection by lansoprazole pretreatment against experimentally induced injury in rats: role of mucosal oxidative damage and sulfhydryl compounds.
|
Toxicol Appl Pharmacol
|
2004
|
0.92
|
|
19
|
Cyclooxygenase-2 inhibition improves vascular endothelial dysfunction in a rat model of endotoxic shock: role of inducible nitric-oxide synthase and oxidative stress.
|
J Pharmacol Exp Ther
|
2004
|
0.88
|
|
20
|
Effects of esomeprazole on healing of nonsteroidal anti-inflammatory drug (NSAID)-induced gastric ulcers in the presence of a continued NSAID treatment: Characterization of molecular mechanisms.
|
Pharmacol Res
|
2010
|
0.87
|
|
21
|
NSAID-induced enteropathy: are the currently available selective COX-2 inhibitors all the same?
|
J Pharmacol Exp Ther
|
2013
|
0.87
|
|
22
|
The role of purinergic pathways in the pathophysiology of gut diseases: pharmacological modulation and potential therapeutic applications.
|
Pharmacol Ther
|
2013
|
0.85
|
|
23
|
A2a receptors mediate inhibitory effects of adenosine on colonic motility in the presence of experimental colitis.
|
Inflamm Bowel Dis
|
2006
|
0.85
|
|
24
|
Emerging role of cyclooxygenase isoforms in the control of gastrointestinal neuromuscular functions.
|
Pharmacol Ther
|
2009
|
0.83
|
|
25
|
PACAP and gastrin regulate the histidine decarboxylase promoter via distinct mechanisms.
|
Am J Physiol Gastrointest Liver Physiol
|
2003
|
0.83
|
|
26
|
Use of selective serotonin reuptake inhibitors during pregnancy and risk of major and cardiovascular malformations: an update.
|
Postgrad Med
|
2010
|
0.82
|
|
27
|
Differential role of cyclooxygenase 1 and 2 isoforms in the modulation of colonic neuromuscular function in experimental inflammation.
|
J Pharmacol Exp Ther
|
2006
|
0.82
|
|
28
|
Inducible nitric oxide synthase is involved in endothelial dysfunction of mesenteric small arteries from hypothyroid rats.
|
Endocrinology
|
2008
|
0.82
|
|
29
|
CCK2 receptors mediate inhibitory effects of cholecystokinin on the motor activity of guinea-pig distal colon.
|
Eur J Pharmacol
|
2006
|
0.82
|
|
30
|
Adenosine pathway and cancer: where do we go from here?
|
Expert Opin Ther Targets
|
2014
|
0.81
|
|
31
|
A holistic view of adenosine in the control of intestinal neuromuscular functions: the enteric 'purinome' concept.
|
Br J Pharmacol
|
2011
|
0.80
|
|
32
|
An integrated assessment of histopathological changes of the enteric neuromuscular compartment in experimental colitis.
|
J Cell Mol Med
|
2014
|
0.79
|
|
33
|
Pharmacological modulation of adenosine receptor pathways and inflammatory disorders: the way towards novel therapeutics?
|
Expert Opin Investig Drugs
|
2011
|
0.79
|
|
34
|
Resistance artery mechanics and composition in angiotensin II-infused mice: effects of cyclooxygenase-1 inhibition.
|
Eur Heart J
|
2011
|
0.79
|
|
35
|
Altered expression pattern of molecular factors involved in colonic smooth muscle functions: an immunohistochemical study in patients with diverticular disease.
|
PLoS One
|
2013
|
0.79
|
|
36
|
Derivatives of benzimidazol-2-ylquinoline and benzimidazol-2-ylisoquinoline as selective A1 adenosine receptor antagonists with stimulant activity on human colon motility.
|
ChemMedChem
|
2011
|
0.77
|
|
37
|
Effects of pantoprazole on ulcer healing delay associated with NSAID treatment.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2008
|
0.77
|
|
38
|
Cyclooxygenase-2 induction after oral surgery does not entirely account for analgesia after selective blockade of cyclooxygenase 2 in the preoperative period.
|
Anesthesiology
|
2006
|
0.77
|
|
39
|
Genetics and pharmacogenetics of aminergic transmitter pathways in functional gastrointestinal disorders.
|
Pharmacogenomics
|
2015
|
0.76
|
|
40
|
Clinical efficacy of esomeprazole in the prevention and healing of gastrointestinal toxicity associated with NSAIDs in elderly patients.
|
Drugs Aging
|
2008
|
0.76
|
|
41
|
Response to Endothelial nitric oxide synthase, cyclooxygenase-2, and essential hypertension: is there an interaction?
|
Hypertension
|
2013
|
0.75
|