Published in BMC Bioinformatics on October 15, 2009
Prediction of peptide reactivity with human IVIg through a knowledge-based approach. PLoS One (2011) 0.77
Unravelling associations between unassigned mass spectrometry peaks with frequent itemset mining techniques. Proteome Sci (2014) 0.75
Revealing the role of VEGFA in clear cell sarcoma of the kidney by protein-protein interaction network and significant pathway analysis. Oncol Lett (2015) 0.75
PhosphoHunter: An Efficient Software Tool for Phosphopeptide Identification. Adv Bioinformatics (2015) 0.75
Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis (1999) 45.01
Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry. Nat Methods (2007) 25.29
Comparative evaluation of mass spectrometry platforms used in large-scale proteomics investigations. Nat Methods (2005) 6.73
Rapid identification of proteins by peptide-mass fingerprinting. Curr Biol (1993) 5.87
Automated protein identification by tandem mass spectrometry: issues and strategies. Mass Spectrom Rev (2006) 1.40
Modular, scriptable and automated analysis tools for high-throughput peptide mass fingerprinting. Bioinformatics (2004) 1.38
Searching for biomarkers of Aurora-A kinase activity: identification of in vitro substrates through a modified KESTREL approach. J Proteome Res (2005) 1.06
Valid data from large-scale proteomics studies. Nat Methods (2005) 0.99
Identification of yeast proteins from two-dimensional gels: working out spot cross-contamination. Electrophoresis (1998) 0.98
Protein and peptide identification algorithms using MS for use in high-throughput, automated pipelines. Proteomics (2005) 0.97
Wavelet-based method for noise characterization and rejection in high-performance liquid chromatography coupled to mass spectrometry. Anal Chem (2008) 0.96
OLAV-PMF: a novel scoring scheme for high-throughput peptide mass fingerprinting. J Proteome Res (2004) 0.94
Scoring methods in MALDI peptide mass fingerprinting: ChemScore, and the ChemApplex program. J Am Soc Mass Spectrom (2002) 0.93
A new approach for the analysis of mass spectrometry data for biomarker discovery. AMIA Annu Symp Proc (2006) 0.88
Predictive pharmacokinetic-pharmacodynamic modeling of tumor growth kinetics in xenograft models after administration of anticancer agents. Cancer Res (2004) 2.47
The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation. EMBO J (2008) 2.36
Leptin:adiponectin ratio is an independent predictor of intima media thickness of the common carotid artery. Stroke (2007) 2.04
Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases. J Biol Chem (2006) 2.04
Crystal structures of anaplastic lymphoma kinase in complex with ATP competitive inhibitors. Biochemistry (2010) 1.94
PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer. Mol Cancer Ther (2007) 1.67
A large scale analysis of information-theoretic network complexity measures using chemical structures. PLoS One (2009) 1.61
PHA-680632, a novel Aurora kinase inhibitor with potent antitumoral activity. Clin Cancer Res (2006) 1.61
Prognostic effect of circulating adiponectin in a randomized 2 x 2 trial of low-dose tamoxifen and fenretinide in premenopausal women at risk for breast cancer. J Clin Oncol (2011) 1.56
Targeting the mitotic checkpoint for cancer therapy with NMS-P715, an inhibitor of MPS1 kinase. Cancer Res (2010) 1.48
Crystal structure of the T315I Abl mutant in complex with the aurora kinases inhibitor PHA-739358. Cancer Res (2007) 1.42
Temporal data mining for the quality assessment of hemodialysis services. Artif Intell Med (2005) 1.27
Structural basis for CARM1 inhibition by indole and pyrazole inhibitors. Biochem J (2011) 1.20
Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. Proc Natl Acad Sci U S A (2003) 1.15
Amino acid-dependent activation of liver estrogen receptor alpha integrates metabolic and reproductive functions via IGF-1. Cell Metab (2011) 1.10
Searching for biomarkers of Aurora-A kinase activity: identification of in vitro substrates through a modified KESTREL approach. J Proteome Res (2005) 1.06
Characterization of a synthetic bacterial self-destruction device for programmed cell death and for recombinant proteins release. J Biol Eng (2011) 1.02
The use of benthic indicators in Europe: from the Water Framework Directive to the Marine Strategy Framework Directive. Mar Pollut Bull (2010) 1.01
Effect of fenretinide and low-dose tamoxifen on insulin sensitivity in premenopausal women at high risk for breast cancer. Cancer Res (2008) 1.01
Positive energy balance is associated with accelerated muscle atrophy and increased erythrocyte glutathione turnover during 5 wk of bed rest. Am J Clin Nutr (2008) 1.01
Characterization of an inducible promoter in different DNA copy number conditions. BMC Bioinformatics (2012) 1.01
The I148M PNPLA3 polymorphism influences serum adiponectin in patients with fatty liver and healthy controls. BMC Gastroenterol (2012) 1.00
Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms. J Mol Biol (2007) 0.99
A hierarchical Naïve Bayes Model for handling sample heterogeneity in classification problems: an application to tissue microarrays. BMC Bioinformatics (2006) 0.98
Bottom-up engineering of biological systems through standard bricks: a modularity study on basic parts and devices. PLoS One (2012) 0.98
A new approach to phosphoserine and phosphothreonine analysis in peptides and proteins: chemical modification, enrichment via solid-phase reversible binding, and analysis by mass spectrometry. Anal Bioanal Chem (2003) 0.97
Dietary iron overload induces visceral adipose tissue insulin resistance. Am J Pathol (2013) 0.96
Pharmacokinetics of orally administered melatonin in critically ill patients. J Pineal Res (2010) 0.95
Activation of the Y1 receptor by neuropeptide Y regulates the growth of prostate cancer cells. Endocrinology (2005) 0.95
Modeling of human tumor xenografts and dose rationale in oncology. Drug Discov Today Technol (2013) 0.91
TA-clustering: cluster analysis of gene expression profiles through Temporal Abstractions. Int J Med Inform (2005) 0.90
A standard vector for the chromosomal integration and characterization of BioBrick™ parts in Escherichia coli. J Biol Eng (2013) 0.89
Identification of Myb-binding protein 1A (MYBBP1A) as a novel substrate for aurora B kinase. J Biol Chem (2010) 0.89
Minimal model S(I)=0 problem in NIDDM subjects: nonzero Bayesian estimates with credible confidence intervals. Am J Physiol Endocrinol Metab (2002) 0.89
Monolithic capillary columns for liquid chromatography-electrospray ionization mass spectrometry in proteomic and genomic research. J Chromatogr B Analyt Technol Biomed Life Sci (2002) 0.89
Multiplexing and demultiplexing logic functions for computing signal processing tasks in synthetic biology. Biotechnol J (2011) 0.87
The dopamine-somatostatin chimeric compound BIM-23A760 exerts antiproliferative and cytotoxic effects in human non-functioning pituitary tumors by activating ERK1/2 and p38 pathways. Cancer Lett (2009) 0.86
The natural antioxidant alpha-lipoic acid induces p27(Kip1)-dependent cell cycle arrest and apoptosis in MCF-7 human breast cancer cells. Eur J Pharmacol (2010) 0.86
Predictive pharmacokinetic-pharmacodynamic modeling of tumor growth after administration of an anti-angiogenic agent, bevacizumab, as single-agent and combination therapy in tumor xenografts. Cancer Chemother Pharmacol (2013) 0.86
Modulatory actions of neuropeptide Y on prostate cancer growth: role of MAP kinase/ERK 1/2 activation. Adv Exp Med Biol (2007) 0.86
Precedence Temporal Networks to represent temporal relationships in gene expression data. J Biomed Inform (2007) 0.86
The two tryptophans of β2-microglobulin have distinct roles in function and folding and might represent two independent responses to evolutionary pressure. BMC Evol Biol (2011) 0.84
Comprehensive two-dimensional gas chromatography using large sample volume injection for the determination of polynuclear aromatic hydrocarbons in complex matrices. J Chromatogr A (2003) 0.82
Identification of candidate substrates for poly(ADP-ribose) polymerase-2 (PARP2) in the absence of DNA damage using high-density protein microarrays. FEBS J (2011) 0.82
GC-MS profiling of the phytochemical constituents of the oleoresin from Copaifera langsdorffii Desf. and a preliminary in vivo evaluation of its antipsoriatic effect. Int J Pharm (2012) 0.82
Random walk models for bayesian clustering of gene expression profiles. Appl Bioinformatics (2005) 0.82
A predictive pharmacokinetic-pharmacodynamic model of tumor growth kinetics in xenograft mice after administration of anticancer agents given in combination. Cancer Chemother Pharmacol (2013) 0.82
Protein biomarkers for the prediction of cardiovascular disease in type 2 diabetes. Diabetologia (2015) 0.81
A model-based approach to the in vitro evaluation of anticancer activity. Cancer Chemother Pharmacol (2008) 0.81
Mouse embryonic stem cells that survive γ-rays exposure maintain pluripotent differentiation potential and genome stability. J Cell Physiol (2012) 0.81
Phaseolus vulgaris extract affects glycometabolic and appetite control in healthy human subjects. Br J Nutr (2012) 0.81
Plasma concentrations of the enantiomers of fluoxetine and norfluoxetine: sources of variability and preliminary observations on relations with clinical response. Ther Drug Monit (2002) 0.81
Adipokine actions on cartilage homeostasis. Adv Clin Chem (2011) 0.80
Metabolic syndrome, adipokines and hormonal factors in pharmacologically untreated adult elderly subjects from the Brisighella Heart Study historical cohort. Obes Facts (2012) 0.80
Inferring gene regulatory networks by integrating static and dynamic data. Int J Med Inform (2007) 0.80
Plasma nerve growth factor (NGF) and inflammatory cytokines (IL-6 and MCP-1) in young and adult subjects with Down syndrome: an interesting pathway. Neuro Endocrinol Lett (2006) 0.80
On the myths of indicator species: issues and further consideration in the use of static concepts for ecological applications. PLoS One (2013) 0.80
Multidimensional proteomic analysis of photosynthetic membrane proteins by liquid extraction-ultracentrifugation-liquid chromatography-mass spectrometry. Proteomics (2004) 0.80
Modelling the effects of cell-to-cell variability on the output of interconnected gene networks in bacterial populations. BMC Syst Biol (2015) 0.80
Impaired expression of insulin-like growth factor-1 system in skeletal muscle of amyotrophic lateral sclerosis patients. Muscle Nerve (2012) 0.80
Adiponectin interactions in bone and cartilage biology and disease. Vitam Horm (2012) 0.80
Phosphorylation of TCTP as a marker for polo-like kinase-1 activity in vivo. Anticancer Res (2010) 0.80
Accurate peak list extraction from proteomic mass spectra for identification and profiling studies. BMC Bioinformatics (2010) 0.79
Role of neuropeptide Y and its receptors in the progression of endocrine-related cancer. Peptides (2007) 0.79
Synthesis and biological evaluation of RGD peptidomimetic-paclitaxel conjugates bearing lysosomally cleavable linkers. Chemistry (2015) 0.79
Hierarchical Naive Bayes for genetic association studies. BMC Bioinformatics (2012) 0.79
Regulation of the wild-type and Y1235D mutant Met kinase activation. Biochemistry (2005) 0.79
TGI-Simulator: a visual tool to support the preclinical phase of the drug discovery process by assessing in silico the effect of an anticancer drug. Comput Methods Programs Biomed (2011) 0.79
Discovery of 2-(cyclohexylmethylamino)pyrimidines as a new class of reversible valosine containing protein inhibitors. J Med Chem (2014) 0.79
In vitro cell growth pharmacodynamic studies: a new nonparametric approach to determining the relative importance of drug concentration and treatment time. Cancer Chemother Pharmacol (2003) 0.78
Novel genetic susceptibility loci for diabetic end-stage renal disease identified through robust naive Bayes classification. Diabetologia (2014) 0.78
Adipokines and sexual hormones associated with the components of the metabolic syndrome in pharmacologically untreated subjects: data from the brisighella heart study. Int J Endocrinol (2011) 0.78
Integrating model-based decision support in a multi-modal reasoning system for managing type 1 diabetic patients. Artif Intell Med (2003) 0.78
Low-intermediate dose testosterone replacement therapy by different pharmaceutical preparations improves frailty score in elderly hypogonadal hyperglycaemic patients. Aging Male (2013) 0.77
Osteocalcin as a potential risk biomarker for cardiovascular and metabolic diseases. Clin Chem Lab Med (2016) 0.77
BDNF Serum Levels with Respect to Multidimensional Assessment in Amyotrophic Lateral Sclerosis. Neurodegener Dis (2016) 0.76
Cholinergic regulation of neuropeptide Y synthesis and release in human neuroblastoma cells. Peptides (2007) 0.76
Hepatic steatosis and PNPLA3 I148M variant are associated with serum Fetuin-A independently of insulin resistance. Eur J Clin Invest (2014) 0.76
Regulation of prostate cancer cell proliferation by somatostatin receptor activation. Mol Cell Endocrinol (2009) 0.75
Theranostic nanocages for imaging and photothermal therapy of prostate cancer cells by active targeting of neuropeptide-Y receptor. Bioconjug Chem (2016) 0.75
Inferring gene expression networks via static and dynamic data integration. Stud Health Technol Inform (2006) 0.75
Methods for genetic optimization of biocatalysts for biofuel production from dairy waste through synthetic biology. Conf Proc IEEE Eng Med Biol Soc (2015) 0.75
Antiproliferative activity on human prostate carcinoma cell lines of new peptidomimetics containing the spiroazepinoindolinone scaffold. Bioorg Med Chem (2013) 0.75
Changes in stress hormones and metabolism during a 105-day simulated Mars mission. Aviat Space Environ Med (2014) 0.75
Total, free and bound leptin and thyroid function in elderly women with different body weights. Clin Endocrinol (Oxf) (2007) 0.75