Published in J Virol on January 01, 2010
NS4B self-interaction through conserved C-terminal elements is required for the establishment of functional hepatitis C virus replication complexes. J Virol (2011) 1.41
Membranous replication factories induced by plus-strand RNA viruses. Viruses (2014) 1.40
Architecture and biogenesis of plus-strand RNA virus replication factories. World J Virol (2013) 1.30
RNA-RNA and RNA-protein interactions in coronavirus replication and transcription. RNA Biol (2011) 1.21
Severe acute respiratory syndrome coronavirus nonstructural proteins 3, 4, and 6 induce double-membrane vesicles. MBio (2013) 1.04
Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus. PLoS Pathog (2014) 0.93
Mobility and interactions of coronavirus nonstructural protein 4. J Virol (2011) 0.93
Coronaviruses: an overview of their replication and pathogenesis. Methods Mol Biol (2015) 0.85
Aminoterminal amphipathic α-helix AH1 of hepatitis C virus nonstructural protein 4B possesses a dual role in RNA replication and virus production. PLoS Pathog (2014) 0.85
Biogenesis and dynamics of the coronavirus replicative structures. Viruses (2012) 0.84
Competitive fitness in coronaviruses is not correlated with size or number of double-membrane vesicles under reduced-temperature growth conditions. MBio (2014) 0.84
Involvement of autophagy in coronavirus replication. Viruses (2012) 0.83
Untangling membrane rearrangement in the nidovirales. DNA Cell Biol (2014) 0.81
Murine hepatitis virus nsp4 N258T mutants are not temperature-sensitive. Virology (2012) 0.80
Mutations across murine hepatitis virus nsp4 alter virus fitness and membrane modifications. J Virol (2014) 0.79
Extensive coronavirus-induced membrane rearrangements are not a determinant of pathogenicity. Sci Rep (2016) 0.75
Intracellular functions of N-linked glycans. Science (2001) 8.39
Characterization of an efficient coronavirus ribosomal frameshifting signal: requirement for an RNA pseudoknot. Cell (1989) 6.62
Virus-encoded proteinases and proteolytic processing in the Nidovirales. J Gen Virol (2000) 4.83
Cellular origin and ultrastructure of membranes induced during poliovirus infection. J Virol (1996) 4.41
Systematic assembly of a full-length infectious cDNA of mouse hepatitis virus strain A59. J Virol (2002) 4.29
Remodeling the endoplasmic reticulum by poliovirus infection and by individual viral proteins: an autophagy-like origin for virus-induced vesicles. J Virol (2000) 4.15
The complete sequence (22 kilobases) of murine coronavirus gene 1 encoding the putative proteases and RNA polymerase. Virology (1991) 4.07
Protein degradation in the endoplasmic reticulum. Cell (1990) 4.04
RNA replication of mouse hepatitis virus takes place at double-membrane vesicles. J Virol (2002) 3.69
Coronaviruses post-SARS: update on replication and pathogenesis. Nat Rev Microbiol (2009) 3.63
Open reading frame 1a-encoded subunits of the arterivirus replicase induce endoplasmic reticulum-derived double-membrane vesicles which carry the viral replication complex. J Virol (1999) 3.51
Viral RNA replication in association with cellular membranes. Curr Top Microbiol Immunol (2005) 3.18
Brome mosaic virus helicase- and polymerase-like proteins colocalize on the endoplasmic reticulum at sites of viral RNA synthesis. J Virol (1996) 3.17
SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum. PLoS Biol (2008) 3.16
How N-linked oligosaccharides affect glycoprotein folding in the endoplasmic reticulum. Mol Biol Cell (1994) 3.11
Formation of plant RNA virus replication complexes on membranes: role of an endoplasmic reticulum-targeted viral protein. EMBO J (1997) 2.99
The primary structure and expression of the second open reading frame of the polymerase gene of the coronavirus MHV-A59; a highly conserved polymerase is expressed by an efficient ribosomal frameshifting mechanism. Nucleic Acids Res (1990) 2.71
Virus factories: associations of cell organelles for viral replication and morphogenesis. Biol Cell (2005) 2.65
Genetic interaction of flavivirus nonstructural proteins NS1 and NS4A as a determinant of replicase function. J Virol (1999) 2.44
The role of N-glycans in the secretory pathway. Cell (1995) 2.05
Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activity. J Virol (2004) 1.97
Non-structural proteins 2 and 3 interact to modify host cell membranes during the formation of the arterivirus replication complex. J Gen Virol (2001) 1.93
Glycoproteins: what are the sugar chains for? Trends Biochem Sci (1989) 1.90
Mutagenesis of the N-linked glycosylation sites of the yellow fever virus NS1 protein: effects on virus replication and mouse neurovirulence. Virology (1996) 1.87
Coronavirus protein processing and RNA synthesis is inhibited by the cysteine proteinase inhibitor E64d. Virology (1995) 1.80
Identification and characterization of a serine-like proteinase of the murine coronavirus MHV-A59. J Virol (1995) 1.76
Molecular anatomy of mouse hepatitis virus persistence: coevolution of increased host cell resistance and virus virulence. J Virol (1996) 1.74
Identification of the catalytic sites of a papain-like cysteine proteinase of murine coronavirus. J Virol (1993) 1.74
Mouse hepatitis virus strain A59 RNA polymerase gene ORF 1a: heterogeneity among MHV strains. Virology (1994) 1.73
Intracellular processing of the N-terminal ORF 1a proteins of the coronavirus MHV-A59 requires multiple proteolytic events. Virology (1992) 1.67
Identification of the murine coronavirus MP1 cleavage site recognized by papain-like proteinase 2. J Virol (2003) 1.47
Mouse hepatitis virus (MHV-2). Plaque assay and propagation in mouse cell line DBT cells. Jpn J Microbiol (1976) 1.43
Intracellular and in vitro-translated 27-kDa proteins contain the 3C-like proteinase activity of the coronavirus MHV-A59. Virology (1996) 1.43
Characterization of the expression, intracellular localization, and replication complex association of the putative mouse hepatitis virus RNA-dependent RNA polymerase. J Virol (2003) 1.41
Identification of mouse hepatitis virus papain-like proteinase 2 activity. J Virol (2000) 1.34
Cleavage between replicase proteins p28 and p65 of mouse hepatitis virus is not required for virus replication. J Virol (2004) 1.32
Localization and membrane topology of coronavirus nonstructural protein 4: involvement of the early secretory pathway in replication. J Virol (2007) 1.32
Membrane topology of murine coronavirus replicase nonstructural protein 3. Virology (2007) 1.31
Mouse hepatitis virus replicase protein complexes are translocated to sites of M protein accumulation in the ERGIC at late times of infection. Virology (2001) 1.29
Seeking membranes: positive-strand RNA virus replication complexes. PLoS Biol (2008) 1.18
Host-derived intracellular immunization against mouse hepatitis virus infection. Virology (1997) 1.16
Replication of murine hepatitis virus is regulated by papain-like proteinase 1 processing of nonstructural proteins 1, 2, and 3. J Virol (2006) 1.13
Mutation in murine coronavirus replication protein nsp4 alters assembly of double membrane vesicles. Virology (2008) 1.13
Formation of the arterivirus replication/transcription complex: a key role for nonstructural protein 3 in the remodeling of intracellular membranes. J Virol (2008) 1.12
Genetic analysis of Murine hepatitis virus nsp4 in virus replication. J Virol (2007) 1.12
Detection of nonstructural protein 6 in murine coronavirus-infected cells and analysis of the transmembrane topology by using bioinformatics and molecular approaches. J Virol (2009) 0.98
Processing of the replicase of murine coronavirus: papain-like proteinase 2 (PLP2) acts to generate p150 and p44. Adv Exp Med Biol (2001) 0.88
Systematic assembly of a full-length infectious cDNA of mouse hepatitis virus strain A59. J Virol (2002) 4.29
Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus. PLoS Pathog (2011) 3.26
Coronavirus replication complex formation utilizes components of cellular autophagy. J Biol Chem (2003) 2.96
Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus. Proc Natl Acad Sci U S A (2003) 2.82
Identification and characterization of severe acute respiratory syndrome coronavirus replicase proteins. J Virol (2004) 2.38
Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice. J Virol (2005) 2.22
Distribution of Mycobacterium ulcerans in buruli ulcer endemic and non-endemic aquatic sites in Ghana. PLoS Negl Trop Dis (2008) 2.16
Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice. Proc Natl Acad Sci U S A (2008) 1.97
Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics. PLoS Pathog (2013) 1.75
The nsp2 replicase proteins of murine hepatitis virus and severe acute respiratory syndrome coronavirus are dispensable for viral replication. J Virol (2005) 1.71
Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing. PLoS Pathog (2010) 1.67
Single-amino-acid substitutions in open reading frame (ORF) 1b-nsp14 and ORF 2a proteins of the coronavirus mouse hepatitis virus are attenuating in mice. J Virol (2005) 1.54
High fidelity of murine hepatitis virus replication is decreased in nsp14 exoribonuclease mutants. J Virol (2007) 1.54
Coronavirus replication does not require the autophagy gene ATG5. Autophagy (2007) 1.50
Characterization of the expression, intracellular localization, and replication complex association of the putative mouse hepatitis virus RNA-dependent RNA polymerase. J Virol (2003) 1.41
Use of intravenous zanamivir after development of oseltamivir resistance in a critically Ill immunosuppressed child infected with 2009 pandemic influenza A (H1N1) virus. Clin Infect Dis (2010) 1.33
Mutagenesis of the murine hepatitis virus nsp1-coding region identifies residues important for protein processing, viral RNA synthesis, and viral replication. Virology (2005) 1.26
A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease. Nat Med (2012) 1.26
Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses. J Infect Dis (2013) 1.23
Processing of open reading frame 1a replicase proteins nsp7 to nsp10 in murine hepatitis virus strain A59 replication. J Virol (2007) 1.22
Intracellular localization and protein interactions of the gene 1 protein p28 during mouse hepatitis virus replication. J Virol (2004) 1.15
Replication of murine hepatitis virus is regulated by papain-like proteinase 1 processing of nonstructural proteins 1, 2, and 3. J Virol (2006) 1.13
Integrin alphavbeta1 promotes infection by human metapneumovirus. Proc Natl Acad Sci U S A (2009) 1.13
Genetic analysis of Murine hepatitis virus nsp4 in virus replication. J Virol (2007) 1.12
Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site. Nat Struct Mol Biol (2012) 1.11
Murine hepatitis virus replicase protein nsp10 is a critical regulator of viral RNA synthesis. J Virol (2007) 1.06
ANDES: Statistical tools for the ANalyses of DEep Sequencing. BMC Res Notes (2010) 1.05
Dual analysis for mycobacteria and propionibacteria in sarcoidosis BAL. J Clin Immunol (2012) 1.04
Analysis of murine hepatitis virus strain A59 temperature-sensitive mutant TS-LA6 suggests that nsp10 plays a critical role in polyprotein processing. J Virol (2007) 1.04
Multiple mycobacterial antigens are targets of the adaptive immune response in pulmonary sarcoidosis. Respir Res (2010) 1.04
A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant. MBio (2014) 0.95
Genetic and pharmacologic alteration of cathepsin expression influences reovirus pathogenesis. J Virol (2009) 0.93
Implications of altered replication fidelity on the evolution and pathogenesis of coronaviruses. Curr Opin Virol (2012) 0.88
Association of maternal medical conditions and unfavorable birth outcomes: findings from the 1996-2003 Mississippi linked birth and death data. Matern Child Health J (2011) 0.87
A novel mutation in murine hepatitis virus nsp5, the viral 3C-like proteinase, causes temperature-sensitive defects in viral growth and protein processing. J Virol (2008) 0.87
Coronavirus replicase-reporter fusions provide quantitative analysis of replication and replication complex formation. J Virol (2014) 0.85
Effects of mutagenesis of murine hepatitis virus nsp1 and nsp14 on replication in culture. Adv Exp Med Biol (2006) 0.84
B cell-intrinsic and -extrinsic regulation of antibody responses by PARP14, an intracellular (ADP-ribosyl)transferase. J Immunol (2013) 0.84
SARS coronavirus replicase proteins in pathogenesis. Virus Res (2007) 0.83
The nsp2 proteins of mouse hepatitis virus and SARS coronavirus are dispensable for viral replication. Adv Exp Med Biol (2006) 0.83
Murine coronaviruses encoding nsp2 at different genomic loci have altered replication, protein expression, and localization. J Virol (2008) 0.82
Studies of culture conditions and environmental stability of human metapneumovirus. Virus Res (2010) 0.82
Exchange of the coronavirus replicase polyprotein cleavage sites alters protease specificity and processing. J Virol (2010) 0.81
Murine hepatitis virus nsp4 N258T mutants are not temperature-sensitive. Virology (2012) 0.80
Chimeric exchange of coronavirus nsp5 proteases (3CLpro) identifies common and divergent regulatory determinants of protease activity. J Virol (2013) 0.80
Body mass index and health related quality of life in elementary school children: a pilot study. Health Qual Life Outcomes (2008) 0.79
Genetic determinants of reovirus pathogenesis in a murine model of respiratory infection. J Virol (2013) 0.77
MHV-A59 ORF1a replicase protein nsp7-nsp10 processing in replication. Adv Exp Med Biol (2006) 0.76
Unilateral facial paralysis occurring in an infant with enteroviral otitis media and aseptic meningitis. J Emerg Med (2002) 0.75