Luc Willems

Author PubWeight™ 45.33‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The HTLV-1 Tax interactome. Retrovirology 2008 2.02
2 Reduction of B cell turnover in chronic lymphocytic leukaemia. Br J Haematol 2008 1.74
3 Mechanisms of leukemogenesis induced by bovine leukemia virus: prospects for novel anti-retroviral therapies in human. Retrovirology 2007 1.71
4 Lymphocyte kinetics: the interpretation of labelling data. Trends Immunol 2002 1.44
5 Quantifying lymphocyte kinetics in vivo using carboxyfluorescein diacetate succinimidyl ester (CFSE). Proc Biol Sci 2006 1.24
6 Preventive and therapeutic strategies for bovine leukemia virus: lessons for HTLV. Viruses 2011 1.14
7 Cell dynamics and immune response to BLV infection: a unifying model. Front Biosci 2007 1.13
8 Interaction of retroviral Tax oncoproteins with tristetraprolin and regulation of tumor necrosis factor-alpha expression. J Natl Cancer Inst 2003 1.08
9 Oncoviral bovine leukemia virus G4 and human T-cell leukemia virus type 1 p13(II) accessory proteins interact with farnesyl pyrophosphate synthetase. J Virol 2002 1.04
10 Valproate activates bovine leukemia virus gene expression, triggers apoptosis, and induces leukemia/lymphoma regression in vivo. Proc Natl Acad Sci U S A 2005 1.02
11 Valproate, in combination with pemetrexed and cisplatin, provides additional efficacy to the treatment of malignant mesothelioma. Clin Cancer Res 2009 1.01
12 Increased cell proliferation, but not reduced cell death, induces lymphocytosis in bovine leukemia virus-infected sheep. Proc Natl Acad Sci U S A 2002 1.01
13 Peripheral blood B-cell death compensates for excessive proliferation in lymphoid tissues and maintains homeostasis in bovine leukemia virus-infected sheep. J Virol 2006 0.99
14 Fate of premalignant clones during the asymptomatic phase preceding lymphoid malignancy. Cancer Res 2005 0.99
15 Suppression of tumor growth and cell proliferation by p13II, a mitochondrial protein of human T cell leukemia virus type 1. Proc Natl Acad Sci U S A 2004 0.99
16 Histone deacetylase mediated transcriptional activation reduces proviral loads in HTLV-1 associated myelopathy/tropical spastic paraparesis patients. Blood 2007 0.98
17 Effects of valproate on Tax and HBZ expression in HTLV-1 and HAM/TSP T lymphocytes. Blood 2011 0.98
18 Bovine leukemia virus SU protein interacts with zinc, and mutations within two interacting regions differently affect viral fusion and infectivity in vivo. J Virol 2002 0.98
19 Massive depletion of bovine leukemia virus proviral clones located in genomic transcriptionally active sites during primary infection. PLoS Pathog 2013 0.97
20 Safety of long-term treatment of HAM/TSP patients with valproic acid. Blood 2011 0.97
21 Subcellular localization of the bovine leukemia virus R3 and G4 accessory proteins. J Virol 2002 0.97
22 Valproate synergizes with purine nucleoside analogues to induce apoptosis of B-chronic lymphocytic leukaemia cells. Br J Haematol 2008 0.97
23 Overlapping CRE and E box motifs in the enhancer sequences of the bovine leukemia virus 5' long terminal repeat are critical for basal and acetylation-dependent transcriptional activity of the viral promoter: implications for viral latency. J Virol 2004 0.97
24 Preclinical evidence for a beneficial impact of valproate on the response of small cell lung cancer to first-line chemotherapy. Eur J Cancer 2010 0.94
25 Valproic acid induces apoptosis in chronic lymphocytic leukemia cells through activation of the death receptor pathway and potentiates TRAIL response. Exp Hematol 2007 0.94
26 Interaction of HTLV-1 Tax with minichromosome maintenance proteins accelerates the replication timing program. Blood 2011 0.92
27 Reduced proviral loads during primo-infection of sheep by Bovine Leukemia virus attenuated mutants. Retrovirology 2004 0.92
28 Even attenuated bovine leukemia virus proviruses can be pathogenic in sheep. J Virol 2007 0.91
29 Measurement of ribosomal RNA turnover in vivo by use of deuterium-labeled glucose. Clin Chem 2009 0.88
30 The role of epigenetics in malignant pleural mesothelioma. Lung Cancer 2013 0.87
31 How HTLV-1 may subvert miRNAs for persistence and transformation. Retrovirology 2008 0.87
32 How the DNA damage response determines the fate of HTLV-1 Tax-expressing cells. Retrovirology 2012 0.87
33 Emphasis on cell turnover in two hosts infected by bovine leukemia virus: a rationale for host susceptibility to disease. Vet Immunol Immunopathol 2008 0.86
34 Reduced cell turnover in bovine leukemia virus-infected, persistently lymphocytotic cattle. J Virol 2003 0.85
35 Human T-cell leukemia virus type-1 Tax oncoprotein regulates G-protein signaling. Blood 2006 0.85
36 Spleen-dependent turnover of CD11b peripheral blood B lymphocytes in bovine leukemia virus-infected sheep. J Virol 2006 0.83
37 Reduced cell turnover in lymphocytic monkeys infected by human T-lymphotropic virus type 1. Oncogene 2005 0.82
38 Viral expression directs the fate of B cells in bovine leukemia virus-infected sheep. J Virol 2011 0.81
39 Earlier onset of delta-retrovirus-induced leukemia after splenectomy. PLoS One 2009 0.81
40 In vivo ribosomal RNA turnover is down-regulated in leukaemic cells in chronic lymphocytic leukaemia. Br J Haematol 2010 0.80
41 Gene activation therapy: from the BLV model to HAM/TSP patients. Front Biosci (Schol Ed) 2009 0.79
42 Acetylation at lysine 346 controls the transforming activity of the HTLV-1 Tax oncoprotein in the Rat-1 fibroblast model. Retrovirology 2013 0.79
43 Reduced levels of reactive oxygen species correlate with inhibition of apoptosis, rise in thioredoxin expression and increased bovine leukemia virus proviral loads. Retrovirology 2009 0.78
44 Involvement of glutathione as a mechanism of indirect protection against spontaneous ex vivo apoptosis associated with bovine leukemia virus. J Virol 2004 0.78
45 The homeobox protein MSX2 interacts with tax oncoproteins and represses their transactivation activity. J Biol Chem 2005 0.78
46 WIP1 deficiency inhibits HTLV-1 Tax oncogenesis: novel therapeutic prospects for treatment of ATL? Retrovirology 2012 0.77
47 Facilitating studies of cell proliferation in chronic lymphocytic leukemia. Leuk Res 2010 0.75