Published in Drug Metab Dispos on November 12, 2009
Systems pharmacology modeling predicts delayed presentation and species differences in bile acid-mediated troglitazone hepatotoxicity. Clin Pharmacol Ther (2014) 1.52
Endogenous bile acid disposition in rat and human sandwich-cultured hepatocytes. Toxicol Appl Pharmacol (2012) 0.93
Exploring BSEP inhibition-mediated toxicity with a mechanistic model of drug-induced liver injury. Front Pharmacol (2014) 0.93
Effect of culture time on the basal expression levels of drug transporters in sandwich-cultured primary rat hepatocytes. Drug Metab Dispos (2011) 0.92
Directly acting drugs prostacyclin or nitroglycerine and endothelin receptor blocker bosentan improve cell engraftment in rodent liver. Hepatology (2013) 0.90
An updated review on drug-induced cholestasis: mechanisms and investigation of physicochemical properties and pharmacokinetic parameters. J Pharm Sci (2013) 0.89
Assessment of compound hepatotoxicity using human plateable cryopreserved hepatocytes in a 1536-well-plate format. Assay Drug Dev Technol (2011) 0.86
Cell sources, liver support systems and liver tissue engineering: alternatives to liver transplantation. Int J Stem Cells (2015) 0.80
Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model. Naunyn Schmiedebergs Arch Pharmacol (2017) 0.79
Differential disposition of chenodeoxycholic acid versus taurocholic acid in response to acute troglitazone exposure in rat hepatocytes. Toxicol Sci (2011) 0.79
Engineered three-dimensional liver mimics recapitulate critical rat-specific bile acid pathways. Tissue Eng Part A (2010) 0.78
Sandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury. J Pharm Sci (2016) 0.77
Validation of precision-cut liver slices to study drug-induced cholestasis: a transcriptomics approach. Arch Toxicol (2016) 0.75
Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans. Biomed Res Int (2016) 0.75
A tracer liquid image velocimetry for multi-layer radial flow in bioreactors. Biomed Eng Online (2015) 0.75
Hepatic 3D spheroid models for the detection and study of compounds with cholestatic liability. Sci Rep (2016) 0.75
Stem Cell Strategies to Evaluate Idiosyncratic Drug-induced Liver Injury. J Clin Transl Hepatol (2014) 0.75
Rat precision-cut liver slices predict drug-induced cholestatic injury. Arch Toxicol (2017) 0.75
Intracellular pharmacokinetics of tenofovir diphosphate, carbovir triphosphate, and lamivudine triphosphate in patients receiving triple-nucleoside regimens. J Acquir Immune Defic Syndr (2005) 3.33
Pharmacokinetic and pharmacodynamic characteristics of emtricitabine support its once daily dosing for the treatment of HIV infection. AIDS Res Hum Retroviruses (2004) 2.04
Park-based physical activity among children and adolescents. Am J Prev Med (2011) 1.52
Reducing radiation, revising reference levels. J Am Coll Radiol (2014) 1.08
GF120918, a P-glycoprotein modulator, increases the concentration of unbound amprenavir in the central nervous system in rats. Antimicrob Agents Chemother (2002) 0.94
Endogenous bile acid disposition in rat and human sandwich-cultured hepatocytes. Toxicol Appl Pharmacol (2012) 0.93
Effect of albumin on the biliary clearance of compounds in sandwich-cultured rat hepatocytes. Drug Metab Dispos (2008) 0.88
Simulation of chemical potentials and phase equilibria in two- and three-dimensional square-well fluids: finite size effects. J Phys Chem B (2008) 0.81
Molecular simulation of aqueous electrolyte solubility. 2. Osmotic ensemble Monte Carlo methodology for free energy and solubility calculations and application to NaCl. J Phys Chem B (2011) 0.80
Dual control cell reaction ensemble molecular dynamics: a method for simulations of reactions and adsorption in porous materials. J Chem Phys (2004) 0.79
Childcare outdoor renovation as a built environment health promotion strategy: evaluating the preventing obesity by design intervention. Am J Health Promot (2014) 0.79
Differential disposition of chenodeoxycholic acid versus taurocholic acid in response to acute troglitazone exposure in rat hepatocytes. Toxicol Sci (2011) 0.79
Combination lopinavir and ritonavir alter exogenous and endogenous bile acid disposition in sandwich-cultured rat hepatocytes. Drug Metab Dispos (2012) 0.78
Functional support of the nasal tip. Facial Plast Surg (2012) 0.77
Mesoscale simulation of polymer reaction equilibrium: combining dissipative particle dynamics with reaction ensemble Monte Carlo. I. Polydispersed polymer systems. J Chem Phys (2006) 0.77
Characterization of sandwich-cultured hepatocytes as an in vitro model to assess the hepatobiliary disposition of copper. Drug Metab Dispos (2009) 0.77
Mesoscale simulation of polymer reaction equilibrium: Combining dissipative particle dynamics with reaction ensemble Monte Carlo. II. Supramolecular diblock copolymers. J Chem Phys (2009) 0.77
Molecular simulation of aqueous electrolyte solubility. 3. Alkali-halide salts and their mixtures in water and in hydrochloric acid. J Phys Chem B (2012) 0.77
Molecular force fields for aqueous electrolytes: SPC/E-compatible charged LJ sphere models and their limitations. J Chem Phys (2013) 0.75
Search and rescue in the Intermountain West states. Wilderness Environ Med (2013) 0.75
Double Versus Single Tendon Transfers to Improve Shoulder Function in Brachial Plexus Birth Palsy. J Pediatr Orthop (2017) 0.75
Chemical reaction equilibrium in nanoporous materials: NO dimerization reaction in carbon slit nanopores. J Chem Phys (2006) 0.75
Molecular simulation of aqueous electrolytes: water chemical potential results and Gibbs-Duhem equation consistency tests. J Chem Phys (2013) 0.75
Melanomatous Leptomeningeal Carcinomatosis masquerading as Guillain-Barré Syndrome. Acute Med (2010) 0.75
Automated applications of sandwich-cultured hepatocytes in the evaluation of hepatic drug transport. J Biomol Screen (2011) 0.75
Molecular simulations of aqueous electrolyte solubility: 1. The expanded-ensemble osmotic molecular dynamics method for the solution phase. J Phys Chem B (2005) 0.75