The role of mucus in cough research.

Airway mucus function and dysfunction. N Engl J Med (2010) 4.41

Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis. The Pulmozyme Study Group. N Engl J Med (1994) 7.98

Mucus clearance and lung function in cystic fibrosis with hypertonic saline. N Engl J Med (2006) 5.37

Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): a randomised placebo-controlled trial. Lancet (2005) 3.13

Mucins, mucus, and sputum. Chest (2009) 2.09

MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions. Am J Respir Cell Mol Biol (2004) 1.87

Effects of aerosolized surfactant in patients with stable chronic bronchitis: a prospective randomized controlled trial. JAMA (1997) 1.56

Enhanced clearance of secretions from the human lung after the administration of hypertonic saline aerosol. Am Rev Respir Dis (1978) 1.33

Mucus structure and properties in cystic fibrosis. Paediatr Respir Rev (2007) 1.29

In vivo determination of surface tension in the horse trachea and in vitro model studies. Respir Physiol (1997) 1.13

The role of mucus gel viscosity, spinnability, and adhesive properties in clearance by simulated cough. Biorheology (1989) 1.05

Chemical markers of mucous and serum glycoproteins and their relation to viscosity in mucoid and purulent sputum from various hypersecretory diseases. Am Rev Respir Dis (1978) 1.04

Safety and tolerability of denufosol tetrasodium inhalation solution, a novel P2Y2 receptor agonist: results of a phase 1/phase 2 multicenter study in mild to moderate cystic fibrosis. Pediatr Pulmonol (2005) 1.04

Pulmonary function is negatively correlated with sputum inflammatory markers and cough clearability in subjects with cystic fibrosis but not those with chronic bronchitis. Chest (2006) 1.04

Mucolytics, expectorants, and mucokinetic medications. Respir Care (2007) 0.94

Recent advances in cystic fibrosis. Paediatr Respir Rev (2008) 0.91

Iodinated glycerol has no effect on pulmonary function, symptom score, or sputum properties in patients with stable chronic bronchitis. Chest (1996) 0.89

Mucus, phlegm, and sputum in cystic fibrosis. Respir Care (2009) 0.88

Ring distraction technique for measuring surface tension of sputum: relationship to sputum clearability. J Appl Physiol (1985) (1996) 0.87

The role of DNA and actin polymers on the polymer structure and rheology of cystic fibrosis sputum and depolymerization by gelsolin or thymosin beta 4. Ann N Y Acad Sci (2007) 0.85

The effect of systemic hydration on normal and impaired mucociliary function. Pediatr Pulmonol (1985) 0.84

Thymosin beta4 sequesters actin in cystic fibrosis sputum and decreases sputum cohesivity in vitro. Chest (2006) 0.82

Hyperosmolar solutions stimulate mucus secretion in the ferret trachea. Chest (2003) 0.80

Morphological features of the interaction between mucus and surfactant on the bronchial mucosa. Respiration (1985) 0.78

A new paradigm in respiratory hygiene: modulating respiratory secretions to contain cough bioaerosol without affecting mucus clearance. BMC Pulm Med (2007) 0.78

Designing clinical trials to evaluate mucus clearance therapy. Respir Care (2007) 0.78

Interactions of airflow oscillation, tracheal inclination, and mucus elasticity significantly improve simulated cough clearance. Chest (2009) 0.77

Who will benefit from DNase? Pediatr Pulmonol (1999) 0.76

Mucus transport in a miniaturized simulated cough machine: effect of constriction and serous layer simulant. Biorheology (1989) 0.76

Lack of effect of hydration on sputum production in chronic bronchitis. Chest (1987) 0.75

Clearance of viscoelastic mucus simulant with airflow in a rectangular channel, an experimental study. Technol Health Care (2006) 0.75

Influence of ambroxol on tracheobronchial clearance in simple chronic bronchitis. Eur J Respir Dis (1987) 0.75