Published in Eur J Nucl Med Mol Imaging on November 24, 2009
Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults. Circulation (1993) 4.53
Passive smoking and impaired endothelium-dependent arterial dilatation in healthy young adults. N Engl J Med (1996) 3.59
Physiologic basis for assessing critical coronary stenosis. Instantaneous flow response and regional distribution during coronary hyperemia as measures of coronary flow reserve. Am J Cardiol (1974) 3.39
Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease. N Engl J Med (1995) 3.32
Coronary microvascular dysfunction and prognosis in hypertrophic cardiomyopathy. N Engl J Med (2003) 2.92
Relation between myocardial blood flow and the severity of coronary-artery stenosis. N Engl J Med (1994) 2.68
Long-term prognostic value of 13N-ammonia myocardial perfusion positron emission tomography added value of coronary flow reserve. J Am Coll Cardiol (2009) 2.65
Comparison between the prognostic value of left ventricular function and myocardial perfusion reserve in patients with ischemic heart disease. J Nucl Med (2009) 2.31
Evaluation of the novel myocardial perfusion positron-emission tomography tracer 18F-BMS-747158-02: comparison to 13N-ammonia and validation with microspheres in a pig model. Circulation (2009) 2.15
Reduced myocardial flow reserve in non-insulin-dependent diabetes mellitus. J Am Coll Cardiol (1997) 2.11
Cardiac positron emission tomography. J Am Coll Cardiol (2009) 1.96
Coronary heart disease in smokers: vitamin C restores coronary microcirculatory function. Circulation (2000) 1.93
Influence of age and hemodynamics on myocardial blood flow and flow reserve. Circulation (1993) 1.81
Reproducibility and accuracy of quantitative myocardial blood flow assessment with (82)Rb PET: comparison with (13)N-ammonia PET. J Nucl Med (2009) 1.74
Integrated PET/CT for the assessment of coronary artery disease: a feasibility study. J Nucl Med (2005) 1.69
The effects of plasma insulin and glucose on myocardial blood flow in patients with type 1 diabetes mellitus. J Am Coll Cardiol (2005) 1.66
Prognostic role of myocardial blood flow impairment in idiopathic left ventricular dysfunction. Circulation (2002) 1.66
Increased myocardial perfusion at rest and diminished perfusion reserve in patients with angina and angiographically normal coronary arteries. J Am Coll Cardiol (1990) 1.65
Effects of short-term treatment of hyperlipidemia on coronary vasodilator function and myocardial perfusion in regions having substantial impairment of baseline dilator reverse. Circulation (1998) 1.64
Coronary circulatory dysfunction in insulin resistance, impaired glucose tolerance, and type 2 diabetes mellitus. Circulation (2005) 1.55
Relation among stenosis severity, myocardial blood flow, and flow reserve in patients with coronary artery disease. Circulation (1995) 1.54
A simplified method for quantification of myocardial blood flow using nitrogen-13-ammonia and dynamic PET. J Nucl Med (1993) 1.53
Coronary flow and flow reserve by PET simplified for clinical applications using rubidium-82 or nitrogen-13-ammonia. J Nucl Med (1996) 1.47
Pioglitazone improves myocardial blood flow and glucose utilization in nondiabetic patients with combined hyperlipidemia: a randomized, double-blind, placebo-controlled study. J Am Coll Cardiol (2007) 1.47
A quantitative index of regional blood flow in canine myocardium derived noninvasively with N-13 ammonia and dynamic positron emission tomography. J Am Coll Cardiol (1991) 1.46
Augmented myocardial perfusion reserve after coronary angioplasty quantified by positron emission tomography with H2(15)O. J Am Coll Cardiol (1990) 1.44
Coronary flow reserve calculated from pressure measurements in humans. Validation with positron emission tomography. Circulation (1994) 1.44
Mechanism of uptake and retention of F-18 BMS-747158-02 in cardiomyocytes: a novel PET myocardial imaging agent. J Nucl Cardiol (2007) 1.44
Hypertension and left ventricular hypertrophy are associated with impaired endothelium-mediated relaxation in human coronary resistance vessels. Circulation (1993) 1.40
Improvement of myocardial blood flow to ischemic regions by angiotensin-converting enzyme inhibition with quinaprilat IV: a study using [15O] water dobutamine stress positron emission tomography. J Am Coll Cardiol (1999) 1.40
Position statement: clinical use of cardiac positron emission tomography. Position paper of the Cardiovascular Council of the Society of Nuclear Medicine. J Nucl Med (1993) 1.39
Maximal coronary flow reserve and metabolic coronary vasodilation in patients with diabetes mellitus. Circulation (1995) 1.37
Validation of nitrogen-13-ammonia tracer kinetic model for quantification of myocardial blood flow using PET. J Nucl Med (1993) 1.36
Long-term cigarette smoking impairs endothelium-dependent coronary arterial vasodilator function. Circulation (1995) 1.24
Quantification of regional myocardial blood flow in vivo with H215O. Circulation (1984) 1.24
Assessment of coronary artery disease severity by positron emission tomography. Comparison with quantitative arteriography in 193 patients. Circulation (1989) 1.23
Assessment of coronary flow reserve: comparison between contrast-enhanced magnetic resonance imaging and positron emission tomography. J Am Coll Cardiol (2002) 1.22
Early impairment of coronary flow reserve in young men with borderline hypertension. J Am Coll Cardiol (1998) 1.19
Effects of autonomic neuropathy on coronary blood flow in patients with diabetes mellitus. Circulation (1999) 1.19
Improvement in coronary flow reserve determined by positron emission tomography after 6 months of cholesterol-lowering therapy in patients with early stages of coronary atherosclerosis. Circulation (1999) 1.18
Early detection of abnormal coronary flow reserve in asymptomatic men at high risk for coronary artery disease using positron emission tomography. Circulation (1994) 1.18
Effect of aging on myocardial perfusion reserve. J Nucl Med (1995) 1.13
Positron emission tomography-measured abnormal responses of myocardial blood flow to sympathetic stimulation are associated with the risk of developing cardiovascular events. J Am Coll Cardiol (2005) 1.12
Quantification of regional myocardial blood flow using 13N-ammonia and reoriented dynamic positron emission tomographic imaging. Circulation (1992) 1.12
Assessment of the reproducibility of baseline and hyperemic myocardial blood flow measurements with 15O-labeled water and PET. J Nucl Med (1999) 1.11
Reproducibility of measurements of regional resting and hyperemic myocardial blood flow assessed with PET. J Nucl Med (1996) 1.10
Effects of cardiac sympathetic innervation on coronary blood flow. N Engl J Med (1997) 1.10
Reduced coronary flow reserve in hypercholesterolemic patients without overt coronary stenosis. Circulation (1996) 1.10
Reduction of coronary flow reserve in areas with and without ischemia on stress perfusion imaging in patients with coronary artery disease: a study using oxygen 15-labeled water PET. J Nucl Cardiol (2003) 1.09
A new strategy for the assessment of viable myocardium and regional myocardial blood flow using 15O-water and dynamic positron emission tomography. Circulation (1992) 1.07
Quantification of coronary artery stenosis in vivo. Circ Res (1985) 1.07
Coronary flow reserve is impaired in young men with familial hypercholesterolemia. J Am Coll Cardiol (1996) 1.07
Effects of long-term smoking on myocardial blood flow, coronary vasomotion, and vasodilator capacity. Circulation (1998) 1.07
Rubidium-82 PET-CT for quantitative assessment of myocardial blood flow: validation in a canine model of coronary artery stenosis. Eur J Nucl Med Mol Imaging (2008) 1.06
PET/CT: challenge for nuclear cardiology. J Nucl Med (2005) 1.06
Myocardial tissue fraction--correction for partial volume effects and measure of tissue viability. J Nucl Med (1991) 1.05
The clinical value of myocardial blood flow measurement. J Nucl Med (2009) 1.04
Implementation and evaluation of a two-compartment model for quantification of myocardial perfusion with rubidium-82 and positron emission tomography. Circ Res (1992) 1.04
Low density lipoprotein cholesterol and coronary microvascular dysfunction in hypercholesterolemia. J Am Coll Cardiol (2000) 1.03
Noninvasive quantification of regional myocardial perfusion with rubidium-82 and positron emission tomography. Exploration of a mathematical model. Circulation (1990) 1.00
Simultaneous in vitro and in vivo validation of nitrogen-13-ammonia for the assessment of regional myocardial blood flow. J Nucl Med (1990) 1.00
Repeatability of cold pressor test-induced flow increase assessed with H(2)(15)O and PET. J Nucl Med (2006) 0.97
Noninvasive quantification of regional myocardial flow reserve in patients with coronary atherosclerosis using nitrogen-13 ammonia positron emission tomography. Determination of extent of altered vascular reactivity. J Am Coll Cardiol (1995) 0.97
Detection of serial changes in absolute myocardial perfusion with 82Rb PET. J Nucl Med (2000) 0.96
Improvement of coronary vasodilatation capacity through single LDL apheresis. Atherosclerosis (1998) 0.95
PET-measured heterogeneity in longitudinal myocardial blood flow in response to sympathetic and pharmacologic stress as a non-invasive probe of epicardial vasomotor dysfunction. Eur J Nucl Med Mol Imaging (2006) 0.94
Effect of acute and long-term smoking on myocardial blood flow and flow reserve. Circulation (1995) 0.92
Repeatability of rest and hyperemic myocardial blood flow measurements with 82Rb dynamic PET. J Nucl Med (2008) 0.92
Smoking cessation normalizes coronary endothelial vasomotor response assessed with 15O-water and PET in healthy young smokers. J Nucl Med (2006) 0.92
Decreased endothelium-dependent coronary vasomotion in healthy young smokers. Eur J Nucl Med Mol Imaging (2002) 0.90
Absolute quantification of myocardial blood flow with 13N-ammonia and 3-dimensional PET. J Nucl Med (2007) 0.90
Hyperglycemia rather than insulin resistance is related to reduced coronary flow reserve in NIDDM. Diabetes (1998) 0.89
Olmesartan, but not amlodipine, improves endothelium-dependent coronary dilation in hypertensive patients. J Am Coll Cardiol (2007) 0.89
Assessment of coronary function in children with a history of Kawasaki disease using (15)O-water positron emission tomography. Circulation (2002) 0.88
Chronic inflammation and impaired coronary vasoreactivity in patients with coronary risk factors. Circulation (2004) 0.88
Reduced coronary flow reserve in familial hypercholesterolemia. J Nucl Med (1996) 0.86
Coronary flow reserve in young men with familial combined hyperlipidemia. Circulation (1999) 0.85
Delayed response of myocardial flow reserve to lipid-lowering therapy with fluvastatin. Circulation (1999) 0.84
Homogeneously reduced versus regionally impaired myocardial blood flow in hypertensive patients: two different patterns of myocardial perfusion associated with degree of hypertrophy. J Am Coll Cardiol (1998) 0.84
PET perfusion and vasodilator function after angioplasty for acute myocardial infarction. J Nucl Med (1997) 0.83
Dysregulation of coronary microvascular reactivity in asymptomatic patients with type 2 diabetes mellitus. Eur J Nucl Med Mol Imaging (2002) 0.83
Integrated cardiac PET-CT for the diagnosis and management of CAD. J Nucl Cardiol (2006) 0.83
Insulin improves myocardial blood flow in patients with type 2 diabetes and coronary artery disease. Diabetes (2006) 0.82
Improvement of impaired myocardial vasodilatation due to diffuse coronary atherosclerosis in hypercholesterolemics after lipid-lowering therapy. Circulation (1999) 0.82
L-Arginine normalizes coronary vasomotion in long-term smokers. Circulation (1999) 0.82
Myocardial flow reserve is influenced by both coronary artery stenosis severity and coronary risk factors in patients with suspected coronary artery disease. Eur J Nucl Med Mol Imaging (2006) 0.81
Effect of the angiotensin receptor blocker Valsartan on coronary microvascular flow reserve in moderately hypertensive patients with stable coronary artery disease. Microcirculation (2008) 0.81
Quantification of myocardial flow reserve using positron emission imaging the journey to clinical use. J Am Coll Cardiol (2009) 0.81
Delineation of impaired regional myocardial perfusion by positron emission tomography with H2(15)O. Circulation (1988) 0.81
Mechanisms of coronary flow reserve impairment in human hypertension. An integrated approach by transthoracic and transesophageal echocardiography. Hypertension (1997) 0.80
Reproducibility of measurements of regional myocardial blood flow in a model of coronary artery disease: Comparison of H215O and 13NH3 PET techniques. J Nucl Med (2006) 0.80
Improvement of algorithm for quantification of regional myocardial blood flow using 15O-water with PET. J Nucl Med (2004) 0.78
Systemic nitric oxide synthase inhibition improves coronary flow reserve to adenosine in patients with significant stenoses. Am J Physiol Heart Circ Physiol (2007) 0.78
Assessment of coronary reserve in man: comparison between positron emission tomography with oxygen-15-labeled water and intracoronary Doppler technique. J Nucl Med (1993) 0.78
Application of cardiac molecular imaging using positron emission tomography in evaluation of drug and therapeutics for cardiovascular disorders. Curr Pharm Des (2005) 0.77
Augmentation of myocardial blood flow in hypertensive heart disease by angiotensin antagonists: a comparison of lisinopril and losartan. J Am Coll Cardiol (2002) 0.76
Effects of nateglinide on myocardial microvascular reactivity in Type 2 diabetes mellitus--a randomized study using positron emission tomography. Diabet Med (2005) 0.76
Association between coronary vascular dysfunction and cardiac mortality in patients with and without diabetes mellitus. Circulation (2012) 2.33
Improved cardiac risk assessment with noninvasive measures of coronary flow reserve. Circulation (2011) 2.32
Quantification of myocardial blood flow with 82Rb dynamic PET imaging. Eur J Nucl Med Mol Imaging (2007) 1.85
Coronary vascular dysfunction and prognosis in patients with chronic kidney disease. JACC Cardiovasc Imaging (2012) 1.61
Effects of surgical ventricular reconstruction and mitral complex reconstruction on cardiac oxidative metabolism and efficiency in nonischemic and ischemic dilated cardiomyopathy. JACC Cardiovasc Imaging (2011) 1.42
Reduced 123I-BMIPP uptake implies decreased myocardial flow reserve in patients with chronic stable angina. Eur J Nucl Med Mol Imaging (2005) 1.39
Quantitative analysis of coronary endothelial function with generator-produced 82Rb PET: comparison with 15O-labelled water PET. Eur J Nucl Med Mol Imaging (2010) 1.17
¹⁸F-Fluoro-2-deoxyglucose positron emission tomography in cardiac sarcoidosis. Eur J Nucl Med Mol Imaging (2011) 1.15
Cardiac (18)F-FDG PET/CT with heparin detects infective vegetation in a patient with mechanical valve replacement. Clin Nucl Med (2012) 0.98
Repeatability of rest and hyperemic myocardial blood flow measurements with 82Rb dynamic PET. J Nucl Med (2008) 0.92
Smoking cessation normalizes coronary endothelial vasomotor response assessed with 15O-water and PET in healthy young smokers. J Nucl Med (2006) 0.92
Decreased endothelium-dependent coronary vasomotion in healthy young smokers. Eur J Nucl Med Mol Imaging (2002) 0.90
Incremental diagnostic value of regional myocardial blood flow quantification over relative perfusion imaging with generator-produced rubidium-82 PET. Circ J (2011) 0.90
Quantification of regional myocardial blood flow estimation with three-dimensional dynamic rubidium-82 PET and modified spillover correction model. J Nucl Cardiol (2012) 0.90
Imaging characteristics of cardiac dominant diffuse large B-cell lymphoma demonstrated with MDCT and PET/CT. Eur J Nucl Med Mol Imaging (2013) 0.89
Assessment of coronary function in children with a history of Kawasaki disease using (15)O-water positron emission tomography. Circulation (2002) 0.88
Prognostic significance of dipyridamole-induced ST depression in patients with normal 82Rb PET myocardial perfusion imaging. J Nucl Med (2005) 0.88
Will 3-dimensional PET-CT enable the routine quantification of myocardial blood flow? J Nucl Cardiol (2007) 0.88
Acute and chronic effects of continuous positive airway pressure therapy on left ventricular systolic and diastolic function in patients with obstructive sleep apnea and congestive heart failure. Can J Cardiol (2008) 0.87
Quantification of myocardial blood flow using dynamic 320-row multi-detector CT as compared with ¹⁵O-H₂O PET. Eur Radiol (2014) 0.86
Elevated (18)F-fluorodeoxyglucose uptake in the interventricular septum is associated with atrioventricular block in patients with suspected cardiac involvement sarcoidosis. Eur J Nucl Med Mol Imaging (2013) 0.84
Images in cardiovascular medicine: Imaging of cardiac sarcoid lesions using fasting cardiac 18F-fluorodeoxyglucose positron emission tomography: an autopsy case. Circulation (2010) 0.84
Early detection of cardiac sarcoid lesions with (18)F-fluoro-2-deoxyglucose positron emission tomography. Intern Med (2011) 0.83
Myocardial flow reserve is influenced by both coronary artery stenosis severity and coronary risk factors in patients with suspected coronary artery disease. Eur J Nucl Med Mol Imaging (2006) 0.81
Quantitative analysis of myocardial glucose utilization in patients with left ventricular dysfunction by means of 18F-FDG dynamic positron tomography and three-compartment analysis. Eur J Nucl Med Mol Imaging (2005) 0.81
Improved spillover correction model to quantify myocardial blood flow by 11C-acetate PET: comparison with 15O-H 2O PET. Ann Nucl Med (2014) 0.81
Sensitive detection of myocardial viability in chronic coronary artery disease by ultrasonic integrated backscatter analysis. J Am Soc Echocardiogr (2005) 0.81
In vivo assessment of myocardial glucose uptake by positron emission tomography in adults with the PRKAG2 cardiac syndrome. Circ Cardiovasc Imaging (2009) 0.80
Is ventilatory efficiency (VE/VCO(2) slope) associated with right ventricular oxidative metabolism in patients with congestive heart failure? Eur J Heart Fail (2008) 0.79
Heterogeneous reduction of myocardial oxidative metabolism in patients with ischemic and dilated cardiomyopathy using C-11 acetate PET. Circ J (2008) 0.79
Decreased myocardial beta-adrenergic receptor density in relation to increased sympathetic tone in patients with nonischemic cardiomyopathy. J Nucl Med (2007) 0.78
Recommendations for (18)F-fluorodeoxyglucose positron emission tomography imaging for cardiac sarcoidosis: Japanese Society of Nuclear Cardiology recommendations. Ann Nucl Med (2014) 0.78
Long-term smoking causes more advanced coronary endothelial dysfunction in middle-aged smokers compared to young smokers. Eur J Nucl Med Mol Imaging (2010) 0.78
The validity of multi-center common normal database for identifying myocardial ischemia: Japanese Society of Nuclear Medicine working group database. Ann Nucl Med (2009) 0.78
Right ventricular (18)F-FDG uptake is an important indicator for cardiac involvement in patients with suspected cardiac sarcoidosis. Ann Nucl Med (2014) 0.77
Ischaemic memory imaging using metabolic radiopharmaceuticals: overview of clinical settings and ongoing investigations. Eur J Nucl Med Mol Imaging (2013) 0.77
Images in cardiovascular medicine. Fluorine-18-labeled deoxyglucose positron emission tomography in the diagnosis and management of aortitis with pulmonary artery involvement. Circulation (2005) 0.77
Myocardial oxidative metabolism is increased due to haemodynamic overload in patients with aortic valve stenosis: assessment using 11C-acetate positron emission tomography. Eur J Nucl Med Mol Imaging (2010) 0.77
Electrocardiographically gated ¹¹C-hydroxyephedrine PET for the simultaneous assessment of cardiac sympathetic and contractile functions. Ann Nucl Med (2013) 0.77
Use of multimodality imaging to diagnose cardiac sarcoidosis as well as identify recurrence following heart transplantation. J Nucl Cardiol (2013) 0.76
[Guideline draft of appropriate use of 131I-MIBG for internal radiotherapy of neuroendocrine tumors]. Kaku Igaku (2008) 0.76
Novel iodinated tracers, MIBG and BMIPP, for nuclear cardiology. J Nucl Cardiol (2011) 0.76
Cardiovascular event risk assessment using myocardial perfusion imaging with a view to wide clinical application. Circ J (2011) 0.75
Reply: all vasodilators are not equal. J Am Coll Cardiol (2013) 0.75
Prognostic value of automated SPECT scoring system for coronary artery disease in stress myocardial perfusion and fatty acid metabolism imaging. Int J Cardiovasc Imaging (2012) 0.75
Lung uptake on I-131 therapy and short-term outcome in patients with lung metastasis from differentiated thyroid cancer. Ann Nucl Med (2013) 0.75
[Nuclear cardiology]. Nihon Rinsho (2011) 0.75
Surgical ventricular restoration improves the left ventricle basal wall function using quantitative gated SPECT. Ann Thorac Cardiovasc Surg (2011) 0.75
Whole-body iodine-131 metaiodobenzylguanidine imaging for detection of bone metastases in patients with paraganglioma: comparison with bone scintigraphy. Ann Nucl Med (2007) 0.75
Nuclear medicine practice in Japan: a report of the seventh nationwide survey in 2012. Ann Nucl Med (2014) 0.75
Cardiovascular drug development using radiopharmaceuticals. Curr Pharm Des (2009) 0.75
Interrelation between myocardial oxidative metabolism and diastolic function in patients undergoing surgical ventricular reconstruction. Eur J Nucl Med Mol Imaging (2012) 0.75
Whole body assessment by ¹⁸F-FDG PET in a patient with infective endocarditis. J Nucl Cardiol (2013) 0.75
[Myocardial reporter gene expression imaging]. Nihon Rinsho (2007) 0.75
No reflow-like pattern in intramyocardial coronary artery suggests myocardial ischemia in patients with hypertrophic cardiomyopathy. J Cardiol (2008) 0.75