David A Horwitz

Author PubWeight™ 29.25‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells. J Immunol 2007 3.82
2 Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10. J Immunol 2004 3.51
3 Generation ex vivo of TGF-beta-producing regulatory T cells from CD4+CD25- precursors. J Immunol 2002 2.85
4 Cutting edge: Foxp3+CD4+CD25+ regulatory T cells induced by IL-2 and TGF-beta are resistant to Th17 conversion by IL-6. J Immunol 2008 2.74
5 Antigen-specific transforming growth factor β-induced Treg cells, but not natural Treg cells, ameliorate autoimmune arthritis in mice by shifting the Th17/Treg cell balance from Th17 predominance to Treg cell predominance. Arthritis Rheum 2012 2.43
6 TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells. J Immunol 2006 2.25
7 Role of SMAD and non-SMAD signals in the development of Th17 and regulatory T cells. J Immunol 2010 2.20
8 Increase of CD4+ CD25+ regulatory T-cells in the liver of patients with hepatocellular carcinoma. J Hepatol 2006 1.60
9 Transfer of regulatory T cells generated ex vivo modifies graft rejection through induction of tolerogenic CD4+CD25+ cells in the recipient. Int Immunol 2006 1.19
10 Characterization of protective human CD4CD25 FOXP3 regulatory T cells generated with IL-2, TGF-β and retinoic acid. PLoS One 2010 1.16
11 Synergistic effect of TGF-beta superfamily members on the induction of Foxp3+ Treg. Eur J Immunol 2010 1.13
12 Polyclonal CD4+Foxp3+ Treg cells induce TGFβ-dependent tolerogenic dendritic cells that suppress the murine lupus-like syndrome. J Mol Cell Biol 2012 1.04
13 Identity of mysterious CD4+CD25-Foxp3+ cells in SLE. Arthritis Res Ther 2010 1.03
14 Development of Crohn's disease in a patient taking etanercept. J Rheumatol 2005 0.99
15 Phenotypic and functional characteristic of a newly identified CD8+ Foxp3- CD103+ regulatory T cells. J Mol Cell Biol 2013 0.86
16 The clinical significance of decreased T cell interleukin-2 production in systemic lupus erythematosus: connecting historical dots. Arthritis Rheum 2010 0.77