Published in Chem Res Toxicol on August 01, 2009
Medical marijuana: A panacea or scourge. Lung India (2014) 1.23
DNA damage signaling assessed in individual cells in relation to the cell cycle phase and induction of apoptosis. Crit Rev Clin Lab Sci (2012) 0.92
Urinary concentrations of PAH and VOC metabolites in marijuana users. Environ Int (2015) 0.85
Potent mutagenicity of 3-methylindole requires pulmonary cytochrome P450-mediated bioactivation: a comparison to the prototype cigarette smoke mutagens B(a)P and NNK. Chem Res Toxicol (2010) 0.82
Legalizing Cannabis: A physician's primer on the pulmonary effects of marijuana. Curr Respir Care Rep (2014) 0.77
AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer. Cancer Res (2005) 4.21
Comprehensive comparison of six microarray technologies. Nucleic Acids Res (2004) 2.50
A comparison of mainstream and sidestream marijuana and tobacco cigarette smoke produced under two machine smoking conditions. Chem Res Toxicol (2007) 1.94
Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location. Proc Natl Acad Sci U S A (2008) 1.62
Validation of myocardial acceleration during isovolumic contraction as a novel noninvasive index of right ventricular contractility: comparison with ventricular pressure-volume relations in an animal model. Circulation (2002) 1.51
Brain death leads to abnormal contractile properties of the human donor right ventricle. J Thorac Cardiovasc Surg (2006) 1.44
Detailed review of transgenic rodent mutation assays. Mutat Res (2005) 1.36
Sources, fate, and toxic hazards of oxygenated polycyclic aromatic hydrocarbons (PAHs) at PAH-contaminated sites. Ambio (2007) 1.35
Antitumor activity of the novel vascular targeting agent ZD6126 in a panel of tumor models. Clin Cancer Res (2002) 1.34
CpG island promoter hypermethylation of a novel Ras-effector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutations. Oncogene (2005) 1.31
New and emerging technologies for genetic toxicity testing. Environ Mol Mutagen (2010) 1.28
Air pollution induces heritable DNA mutations. Proc Natl Acad Sci U S A (2002) 1.18
Noninvasive assessment of left ventricular force-frequency relationships using tissue Doppler-derived isovolumic acceleration: validation in an animal model. Circulation (2003) 1.15
Time-of-day influences on static and dynamic postural control. J Athl Train (2007) 1.14
The mutagenic hazards of settled house dust: a review. Mutat Res (2004) 1.14
Systemic ventricular function in patients with transposition of the great arteries after atrial repair: a tissue Doppler and conductance catheter study. J Am Coll Cardiol (2004) 1.12
Maternal and umbilical cord blood levels of mercury, lead, cadmium, and essential trace elements in Arctic Canada. Environ Res (2005) 1.09
AZD5438, a potent oral inhibitor of cyclin-dependent kinases 1, 2, and 9, leads to pharmacodynamic changes and potent antitumor effects in human tumor xenografts. Mol Cancer Ther (2009) 1.09
Mainstream tobacco smoke causes paternal germ-line DNA mutation. Cancer Res (2007) 1.06
The mutagenic hazards of aquatic sediments: a review. Mutat Res (2004) 1.06
Increased mutant frequency by carbon black, but not quartz, in the lacZ and cII transgenes of muta mouse lung epithelial cells. Environ Mol Mutagen (2007) 1.05
Flow cytometric analysis of micronuclei in peripheral blood reticulocytes: II. An efficient method of monitoring chromosomal damage in the rat. Toxicol Sci (2006) 1.01
Simultaneous measurement of benzo[a]pyrene-induced Pig-a and lacZ mutations, micronuclei and DNA adducts in Muta™ Mouse. Environ Mol Mutagen (2011) 1.01
Mutagenicity testing for chemical risk assessment: update of the WHO/IPCS Harmonized Scheme. Mutagenesis (2009) 1.01
In vivo transgenic mutation assays. Mutat Res (2003) 1.01
Mutagenic and carcinogenic hazards of settled house dust. I: Polycyclic aromatic hydrocarbon content and excess lifetime cancer risk from preschool exposure. Environ Sci Technol (2008) 1.00
Black Petrels (Procellaria parkinsoni) patrol the ocean shelf-break: GPS tracking of a vulnerable procellariiform seabird. PLoS One (2010) 1.00
Right ventricular dysfunction in chronic thromboembolic obstruction of the pulmonary artery: a pressure-volume study using the conductance catheter. J Appl Physiol (1985) (2013) 0.99
Molecular insight into the effects of hypothyroidism on the developing cerebellum. Biochem Biophys Res Commun (2005) 0.98
Meeting report: Validation of toxicogenomics-based test systems: ECVAM-ICCVAM/NICEATM considerations for regulatory use. Environ Health Perspect (2006) 0.98
Development and characterization of a stable epithelial cell line from Muta Mouse lung. Environ Mol Mutagen (2003) 0.97
Hepatic gene expression changes in hypothyroid juvenile mice: characterization of a novel negative thyroid-responsive element. Endocrinology (2007) 0.97
A pilot study to assess whether glucagon-like peptide-1 protects the heart from ischemic dysfunction and attenuates stunning after coronary balloon occlusion in humans. Circ Cardiovasc Interv (2011) 0.96
Interlaboratory validation of a CD71-based flow cytometric method (Microflow) for the scoring of micronucleated reticulocytes in mouse peripheral blood. Environ Mol Mutagen (2005) 0.95
ZD6126: a novel small molecule vascular targeting agent. Int J Radiat Oncol Biol Phys (2002) 0.91
Characterisation of Muta™Mouse λgt10-lacZ transgene: evidence for in vivo rearrangements. Mutagenesis (2010) 0.89
Comparison of in-vivo and in-silico methods used for prediction of tissue: plasma partition coefficients in rat. J Pharm Pharmacol (2011) 0.89
Detection of induced male germline mutation: correlations and comparisons between traditional germline mutation assays, transgenic rodent assays and expanded simple tandem repeat instability assays. Mutat Res (2006) 0.89
Mutagenic hazards of complex polycyclic aromatic hydrocarbon mixtures in contaminated soil. Environ Toxicol Chem (2008) 0.89
Novel design and controls for focused DNA microarrays: applications in quality assurance/control and normalization for the Health Canada ToxArray. BMC Genomics (2006) 0.88
Structural identifiability and indistinguishability of compartmental models. Expert Opin Drug Metab Toxicol (2009) 0.88
Subchronic oral exposure to benzo(a)pyrene leads to distinct transcriptomic changes in the lungs that are related to carcinogenesis. Toxicol Sci (2012) 0.87
Cylindrical waveguide electromagnetic exposure system for biological studies with unrestrained mice at 1.9 GHz. Health Phys (2012) 0.87
Remote ischaemic pre-conditioning does not attenuate ischaemic left ventricular dysfunction in humans. Eur J Heart Fail (2009) 0.87
Approaches to determining regulatory values for carcinogens with particular reference to bromate. Toxicology (2006) 0.87
Australian Twin Registry: 30 years of progress. Twin Res Hum Genet (2012) 0.86
Hepatic mRNA, microRNA, and miR-34a-target responses in mice after 28 days exposure to doses of benzo(a)pyrene that elicit DNA damage and mutation. Environ Mol Mutagen (2011) 0.86
Remote ischemic preconditioning stimulus does not reduce microvascular resistance or improve myocardial blood flow in patients undergoing elective percutaneous coronary intervention. Angiology (2008) 0.86
Mutation spectrum in FE1-MUTA(TM) Mouse lung epithelial cells exposed to nanoparticulate carbon black. Environ Mol Mutagen (2010) 0.86
Noradrenaline use in the human donor and relationship with load-independent right ventricular contractility. Transplantation (2004) 0.85
Inhibition of cell signaling by the combi-nitrosourea FD137 in the androgen independent DU145 prostate cancer cell line. Prostate (2004) 0.85
Fractionated X-radiation treatment can elicit an inducible-like radioprotective response that is not dependent on the intrinsic cellular X-radiation resistance/sensitivity. Radiat Res (2006) 0.85
Treatment and sampling protocols for transgenic mutation assays. Environ Mol Mutagen (2003) 0.84
Hepatic genotoxicity and toxicogenomic responses in Muta™Mouse males treated with dibenz[a,h]anthracene. Mutagenesis (2013) 0.84
Flow cytometric analysis of micronuclei in peripheral blood reticulocytes: I. Intra- and interlaboratory comparison with microscopic scoring. Toxicol Sci (2006) 0.84
Mutagenic characteristics of river waters flowing through large metropolitan areas in North America. Mutat Res (2003) 0.83
The combi-targeting concept: in vitro and in vivo fragmentation of a stable combi-nitrosourea engineered to interact with the epidermal growth factor receptor while remaining DNA reactive. Clin Cancer Res (2007) 0.83
Genotoxicity of 3-nitrobenzanthrone and 3-aminobenzanthrone in MutaMouse and lung epithelial cells derived from MutaMouse. Mutagenesis (2008) 0.83
Mass balance soil ingestion estimating methods and their application to inhabitants of rural and wilderness areas: a critical review. Sci Total Environ (2010) 0.83
Analysis of proto-oncogene and heat-shock protein gene expression in human derived cell-lines exposed in vitro to an intermittent 1.9 GHz pulse-modulated radiofrequency field. Int J Radiat Biol (2006) 0.83
The combi-targeting concept: dissection of the binary mechanism of action of the combi-triazene SMA41 in vitro and antitumor activity in vivo. J Pharmacol Exp Ther (2004) 0.83
Recent advances in research on radiofrequency fields and health: 2004-2007. J Toxicol Environ Health B Crit Rev (2009) 0.82
The discovery of AZD5597, a potent imidazole pyrimidine amide CDK inhibitor suitable for intravenous dosing. Bioorg Med Chem Lett (2008) 0.82
Mutagenicity of an aged gasworks soil during bioslurry treatment. Environ Mol Mutagen (2009) 0.81
Toxicogenomic outcomes predictive of forestomach carcinogenesis following exposure to benzo(a)pyrene: relevance to human cancer risk. Toxicol Appl Pharmacol (2013) 0.81
Harnessing genomics to identify environmental determinants of heritable disease. Mutat Res (2012) 0.81
Primary coronary microvascular dysfunction and poor coronary collaterals predict post-percutaneous coronary intervention cardiac necrosis. Coron Artery Dis (2009) 0.81
Comparative study of hops-containing products on human cytochrome P450-mediated metabolism. J Agric Food Chem (2011) 0.81
Gene expression profiling to identify potentially relevant disease outcomes and support human health risk assessment for carbon black nanoparticle exposure. Toxicology (2012) 0.81
Mechanism of action of a novel "combi-triazene" engineered to possess a polar functional group on the alkylating moiety: evidence for enhancement of potency. Biochem Pharmacol (2005) 0.81
Differential responses of EGFR-/AGT-expressing cells to the "combi-triazene" SMA41. Cancer Chemother Pharmacol (2002) 0.80
Use of the comet assay in environmental toxicology. Methods Mol Biol (2008) 0.80
Assessment of genetic damage in peripheral blood of human volunteers exposed (whole-body) to a 200 muT, 60 Hz magnetic field. Int J Radiat Biol (2009) 0.80
Inhibition of epidermal growth factor receptor-mediated signaling by "Combi-triazene" BJ2000, a new probe for Combi-Targeting postulates. J Pharmacol Exp Ther (2002) 0.80
Protection from solar simulated radiation-induced DNA damage in cultured human fibroblasts by three commercially available sunscreens. Can J Physiol Pharmacol (2003) 0.80
Mutagenicity of the oral carcinogen 4-nitroquinoline-1-oxide in cultured BigBlue rat tongue epithelial cells and fibroblasts. Mutat Res (2003) 0.80
Mutagenic and carcinogenic hazards of settled house dust. II: Salmonella mutagenicity. Environ Sci Technol (2008) 0.80
Imidazole pyrimidine amides as potent, orally bioavailable cyclin-dependent kinase inhibitors. Bioorg Med Chem Lett (2008) 0.79
A global toxicogenomic analysis investigating the mechanistic differences between tobacco and marijuana smoke condensates in vitro. Toxicology (2013) 0.79
Coronary collaterals provide a constant scaffold effect on the left ventricle and limit ischemic left ventricular dysfunction in humans. J Appl Physiol (1985) (2012) 0.79
Effects of alpha particle radiation on gene expression in human pulmonary epithelial cells. Int J Hyg Environ Health (2012) 0.79
Poly(ethylene imine) nanocarriers do not induce mutations nor oxidative DNA damage in vitro in MutaMouse FE1 cells. Mol Pharm (2011) 0.79
Biological effects of alpha particle radiation exposure on human monocytic cells. Int J Hyg Environ Health (2011) 0.79
Imidazoles: SAR and development of a potent class of cyclin-dependent kinase inhibitors. Bioorg Med Chem Lett (2008) 0.79
Multiple mechanisms of action of ZR2002 in human breast cancer cells: a novel combi-molecule designed to block signaling mediated by the ERB family of oncogenes and to damage genomic DNA. Int J Cancer (2004) 0.79
A method to estimate sediment ingestion by fish. Aquat Toxicol (2011) 0.79
Genotoxicity, inflammation and physico-chemical properties of fine particle samples from an incineration energy plant and urban air. Mutat Res (2007) 0.78