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1
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Most random gene expression signatures are significantly associated with breast cancer outcome.
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PLoS Comput Biol
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2011
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3.33
|
|
2
|
Human thyroid tumor cell lines derived from different tumor types present a common dedifferentiated phenotype.
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Cancer Res
|
2007
|
1.50
|
|
3
|
Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system.
|
Exp Cell Res
|
2002
|
1.32
|
|
4
|
Activation of dual oxidases Duox1 and Duox2: differential regulation mediated by camp-dependent protein kinase and protein kinase C-dependent phosphorylation.
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J Biol Chem
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2009
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1.29
|
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5
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Hallmarks of cancer: of all cancer cells, all the time?
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Trends Mol Med
|
2012
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1.17
|
|
6
|
Integration and cross-validation of high-throughput gene expression data: comparing heterogeneous data sets.
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FEBS Lett
|
2003
|
1.08
|
|
7
|
Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult.
|
J Endocrinol
|
2007
|
1.04
|
|
8
|
mRNA expression in papillary and anaplastic thyroid carcinoma: molecular anatomy of a killing switch.
|
PLoS One
|
2012
|
0.99
|
|
9
|
Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors".
|
Mol Cell Biol
|
2006
|
0.98
|
|
10
|
Gene expression in human thyrocytes and autonomous adenomas reveals suppression of negative feedbacks in tumorigenesis.
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Proc Natl Acad Sci U S A
|
2005
|
0.98
|
|
11
|
G1/S Cyclins interact with regulatory subunit of PKA via A-kinase anchoring protein, AKAP95.
|
Cell Cycle
|
2006
|
0.97
|
|
12
|
Dual oxidases and hydrogen peroxide in a complex dialogue between host mucosae and bacteria.
|
Trends Mol Med
|
2009
|
0.97
|
|
13
|
cAMP-dependent activation of mammalian target of rapamycin (mTOR) in thyroid cells. Implication in mitogenesis and activation of CDK4.
|
Mol Endocrinol
|
2010
|
0.96
|
|
14
|
Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation.
|
Mol Biol Cell
|
2008
|
0.95
|
|
15
|
Identification of a novel partner of duox: EFP1, a thioredoxin-related protein.
|
J Biol Chem
|
2004
|
0.93
|
|
16
|
Thyroid dysgenesis: multigenic or epigenetic ... or both?
|
Endocrinology
|
2005
|
0.93
|
|
17
|
Distinct specificities of pRb phosphorylation by CDK4 activated by cyclin D1 or cyclin D3: differential involvement in the distinct mitogenic modes of thyroid epithelial cells.
|
Cell Cycle
|
2006
|
0.90
|
|
18
|
A novel partner for D-type cyclins: protein kinase A-anchoring protein AKAP95.
|
Biochem J
|
2004
|
0.90
|
|
19
|
Cyclic AMP-dependent phosphorylation of cyclin D3-bound CDK4 determines the passage through the cell cycle restriction point in thyroid epithelial cells.
|
J Biol Chem
|
2003
|
0.87
|
|
20
|
Extracellular superoxide dismutase is a thyroid differentiation marker down-regulated in cancer.
|
Endocr Relat Cancer
|
2010
|
0.87
|
|
21
|
Cyclic adenosine 3',5'-monophosphate (cAMP)-dependent protein kinases, but not exchange proteins directly activated by cAMP (Epac), mediate thyrotropin/cAMP-dependent regulation of thyroid cells.
|
Endocrinology
|
2007
|
0.87
|
|
22
|
The cyclin D3-CDK4-p27kip1 holoenzyme in thyroid epithelial cells: activation by TSH, inhibition by TGFbeta, and phosphorylations of its subunits demonstrated by two-dimensional gel electrophoresis.
|
Exp Cell Res
|
2003
|
0.86
|
|
23
|
Differential utilization of cyclin D1 and cyclin D3 in the distinct mitogenic stimulations by growth factors and TSH of human thyrocytes in primary culture.
|
Mol Endocrinol
|
2006
|
0.85
|
|
24
|
Long-term EGF/serum-treated human thyrocytes mimic papillary thyroid carcinomas with regard to gene expression.
|
Exp Cell Res
|
2007
|
0.85
|
|
25
|
Role of the different mitogen-activated protein kinase subfamilies in the stimulation of dog and human thyroid epithelial cell proliferation by cyclic adenosine 5'-monophosphate and growth factors.
|
Endocrinology
|
2003
|
0.85
|
|
26
|
Identification and characterization of a novel activated RhoB binding protein containing a PDZ domain whose expression is specifically modulated in thyroid cells by cAMP.
|
Eur J Biochem
|
2002
|
0.84
|
|
27
|
Duox1 is the main source of hydrogen peroxide in the rat thyroid cell line PCCl3.
|
Exp Cell Res
|
2007
|
0.84
|
|
28
|
Signal transduction in the human thyrocyte and its perversion in thyroid tumors.
|
Mol Cell Endocrinol
|
2009
|
0.83
|
|
29
|
Gene expression profiles of post-Chernobyl thyroid cancers.
|
Curr Opin Endocrinol Diabetes Obes
|
2008
|
0.83
|
|
30
|
Gene expression in RET/PTC3 and E7 transgenic mouse thyroids: RET/PTC3 but not E7 tumors are partial and transient models of human papillary thyroid cancers.
|
Endocrinology
|
2008
|
0.82
|
|
31
|
Survival pathways regulating the apoptosis induced by tumour necrosis factor-alpha in primary cultured bovine endothelial cells.
|
Cell Signal
|
2003
|
0.81
|
|
32
|
A coherent organization of differentiation proteins is required to maintain an appropriate thyroid function in the Pendred thyroid.
|
J Clin Endocrinol Metab
|
2010
|
0.81
|
|
33
|
HDGF is dephosphorylated during the early steps of endothelial cell apoptosis in a caspase-dependent way.
|
J Cell Biochem
|
2008
|
0.81
|
|
34
|
Pendrin: the thyrocyte apical membrane iodide transporter?
|
Cell Physiol Biochem
|
2011
|
0.80
|
|
35
|
Phosphatidylinositol 3,4,5-trisphosphate modulation in SHIP2-deficient mouse embryonic fibroblasts.
|
FEBS J
|
2005
|
0.80
|
|
36
|
Normal thyroid structure and function in rhophilin 2-deficient mice.
|
Mol Cell Biol
|
2005
|
0.80
|
|
37
|
The c-Cbl-associated protein and c-Cbl are two new partners of the SH2-containing inositol polyphosphate 5-phosphatase SHIP2.
|
Biochem Biophys Res Commun
|
2003
|
0.79
|
|
38
|
Thyrotropin stimulates the generation of inositol 1,4,5-trisphosphate in human thyroid cells.
|
J Clin Endocrinol Metab
|
2005
|
0.79
|
|
39
|
Role of Epac and protein kinase A in thyrotropin-induced gene expression in primary thyrocytes.
|
Exp Cell Res
|
2012
|
0.79
|
|
40
|
Differential involvement of the actin cytoskeleton in differentiation and mitogenesis of thyroid cells: inactivation of Rho proteins contributes to cyclic adenosine monophosphate-dependent gene expression but prevents mitogenesis.
|
Endocrinology
|
2005
|
0.78
|
|
41
|
Gene expression in thyroid autonomous adenomas provides insight into their physiopathology.
|
Oncogene
|
2005
|
0.78
|
|
42
|
Thyroid gene expression in familial nonautoimmune hyperthyroidism shows common characteristics with hyperfunctioning autonomous adenomas.
|
J Clin Endocrinol Metab
|
2009
|
0.78
|
|
43
|
5-aza-2'-deoxycytidine has minor effects on differentiation in human thyroid cancer cell lines, but modulates genes that are involved in adaptation in vitro.
|
Thyroid
|
2013
|
0.77
|
|
44
|
Thyroid-specific inactivation of KIF3A alters the TSH signaling pathway and leads to hypothyroidism.
|
J Mol Endocrinol
|
2013
|
0.76
|
|
45
|
John B. Stanbury (May 15, 1915-July 6, 2015).
|
Thyroid
|
2015
|
0.75
|
|
46
|
Specificity in signaling and modulators: the Homers.
|
Trends Cell Biol
|
2002
|
0.75
|