Published in Toxicol Sci on December 07, 2009
Neurotoxicity of brominated flame retardants: (in)direct effects of parent and hydroxylated polybrominated diphenyl ethers on the (developing) nervous system. Environ Health Perspect (2011) 1.47
A mechanistic view of polybrominated diphenyl ether (PBDE) developmental neurotoxicity. Toxicol Lett (2013) 1.09
Toxicity of the flame-retardant BDE-49 on brain mitochondria and neuronal progenitor striatal cells enhanced by a PTEN-deficient background. Toxicol Sci (2013) 0.94
Neurobehavioral function and low-level exposure to brominated flame retardants in adolescents: a cross-sectional study. Environ Health (2012) 0.91
Is decabromodiphenyl ether (BDE-209) a developmental neurotoxicant? Neurotoxicology (2010) 0.90
Paraoxonase 2 (PON2) in the mouse central nervous system: a neuroprotective role? Toxicol Appl Pharmacol (2011) 0.89
Developmental neurotoxicity: some old and new issues. ISRN Toxicol (2012) 0.84
The brominated flame retardant BDE-47 causes oxidative stress and apoptotic cell death in vitro and in vivo in mice. Neurotoxicology (2015) 0.79
Persisting effects of a PBDE metabolite, 6-OH-BDE-47, on larval and juvenile zebrafish swimming behavior. Neurotoxicol Teratol (2015) 0.78
BDE99 (2,2',4,4',5-pentabromodiphenyl ether) suppresses differentiation into neurotransmitter phenotypes in PC12 cells. Neurotoxicol Teratol (2013) 0.77
Organic anion transporting polypeptides in the hepatic uptake of PBDE congeners in mice. Toxicol Appl Pharmacol (2011) 0.77
Autism, Mitochondria and Polybrominated Diphenyl Ether Exposure. CNS Neurol Disord Drug Targets (2016) 0.76
Epigenetic effects of low perinatal doses of flame retardant BDE-47 on mitochondrial and nuclear genes in rat offspring. Toxicology (2014) 0.76
Organ-on-a-chip for assessing environmental toxicants. Curr Opin Biotechnol (2017) 0.75
Polybrominated diphenyl ethers in the environment and in people: a meta-analysis of concentrations. Environ Sci Technol (2004) 4.14
An overview of brominated flame retardants in the environment. Chemosphere (2002) 3.87
Brominated flame retardants: cause for concern? Environ Health Perspect (2004) 3.37
Neurobehavioral derangements in adult mice receiving decabrominated diphenyl ether (PBDE 209) during a defined period of neonatal brain development. Toxicol Sci (2003) 2.99
Polybrominated diphenyl ethers: occurrence, dietary exposure, and toxicology. Environ Health Perspect (2001) 2.94
Brominated flame retardants: a novel class of developmental neurotoxicants in our environment? Environ Health Perspect (2001) 2.90
Exposure of Americans to polybrominated diphenyl ethers. J Expo Sci Environ Epidemiol (2007) 2.77
Tissue subcellular fractionation and protein extraction for use in mass-spectrometry-based proteomics. Nat Protoc (2006) 2.52
An overview of commercially used brominated flame retardants, their applications, their use patterns in different countries/regions and possible modes of release. Environ Int (2003) 2.39
Polybrominated diphenyl ethers (PBDEs) in U.S. mothers' milk. Environ Health Perspect (2003) 2.32
High body burdens of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) in California women. Environ Health Perspect (2003) 2.10
Developmental neurotoxicity of polybrominated diphenyl ether (PBDE) flame retardants. Neurotoxicology (2007) 2.07
Polybrominated diphenyl ether flame retardants in the U.S. population: current levels, temporal trends, and comparison with dioxins, dibenzofurans, and polychlorinated biphenyls. J Occup Environ Med (2005) 2.05
Acute postnatal exposure to brominated diphenylether 47 delays neuromotor ontogeny and alters motor activity in mice. Neurotoxicol Teratol (2007) 2.04
Neonatal exposure to polybrominated diphenyl ether (PBDE 153) disrupts spontaneous behaviour, impairs learning and memory, and decreases hippocampal cholinergic receptors in adult mice. Toxicol Appl Pharmacol (2003) 1.99
In vitro profiling of the endocrine-disrupting potency of brominated flame retardants. Toxicol Sci (2006) 1.87
Brominated flame retardants in archived serum samples from Norway: a study on temporal trends and the role of age. Environ Sci Technol (2002) 1.85
A review on human exposure to brominated flame retardants--particularly polybrominated diphenyl ethers. Environ Int (2003) 1.84
Polybrominated diphenyl ethers contamination of United States food. Environ Sci Technol (2004) 1.79
Personal exposure to polybrominated diphenyl ethers (PBDEs) in residential indoor air. Environ Sci Technol (2007) 1.58
Polybrominated diphenyl ether (PBDE) flame retardants: environmental contamination, human body burden and potential adverse health effects. Acta Biomed (2008) 1.54
Polybrominated diphenyl ethers in indoor dust in Ottawa, Canada: implications for sources and exposure. Environ Sci Technol (2005) 1.50
Levels and trends of brominated flame retardants in the European environment. Chemosphere (2006) 1.47
Development of a magnetic particle immunoassay for polybrominated diphenyl ethers and application to environmental and food matrices. Chemosphere (2008) 1.45
Effects of perinatal exposure to a polybrominated diphenyl ether (PBDE 99) on mouse neurobehavioural development. Neurotoxicology (2002) 1.39
Polybrominated diphenyl ethers: neurobehavioral effects following developmental exposure. Neurotoxicology (2003) 1.25
Polybrominated diphenylether levels among United States residents: daily intake and risk of harm to the developing brain and reproductive organs. Integr Environ Assess Manag (2005) 1.22
Brief postnatal PBDE exposure alters learning and the cholinergic modulation of attention in rats. Toxicol Sci (2005) 1.21
Neurotoxicity of domoic Acid in cerebellar granule neurons in a genetic model of glutathione deficiency. Mol Pharmacol (2006) 1.18
Developmental delays and locomotor activity in the C57BL6/J mouse following neonatal exposure to the fully-brominated PBDE, decabromodiphenyl ether. Neurotoxicol Teratol (2007) 1.13
Dioxins, polychlorinated biphenyls and other organohalogen compounds in human milk. Levels, correlations, trends and exposure through breastfeeding. Mol Nutr Food Res (2006) 1.13
Neurotoxicity of the pentabrominated diphenyl ether mixture, DE-71, and hexabromocyclododecane (HBCD) in rat cerebellar granule cells in vitro. Arch Toxicol (2006) 1.13
Neurotoxicity of a polybrominated diphenyl ether mixture (DE-71) in mouse neurons and astrocytes is modulated by intracellular glutathione levels. Toxicol Appl Pharmacol (2008) 1.10
PBDE-47-induced oxidative stress, DNA damage and apoptosis in primary cultured rat hippocampal neurons. Neurotoxicology (2007) 1.10
Differential in vitro neurotoxicity of the flame retardant PBDE-99 and of the PCB Aroclor 1254 in human astrocytoma cells. Toxicol Lett (2004) 1.05
Glutathione levels modulate domoic acid induced apoptosis in mouse cerebellar granule cells. Toxicol Sci (2007) 0.98
Polybrominated diphenyl ethers: human tissue levels and toxicology. Rev Environ Contam Toxicol (2004) 0.97
Quantitative structure-activity relationship modeling on in vitro endocrine effects and metabolic stability involving 26 selected brominated flame retardants. Environ Toxicol Chem (2007) 0.94
Accumulation of PBDE-47 in primary cultures of rat neocortical cells. Toxicol Sci (2004) 0.94
Effects of PBDE-47 on cytotoxicity and genotoxicity in human neuroblastoma cells in vitro. Mutat Res (2007) 0.93
Polybrominated diphenyl ether (PBDE) effects in rat neuronal cultures: 14C-PBDE accumulation, biological effects, and structure-activity relationships. Toxicol Sci (2005) 0.93
Comparative oxygen radical formation and toxicity of BDE 47 in rainbow trout cell lines. Mar Environ Res (2008) 0.87
Apoptosis induction on human hepatoma cells Hep G2 of decabrominated diphenyl ether (PBDE-209). Toxicol Lett (2007) 0.85
Developmental neurotoxicity of polybrominated diphenyl ether (PBDE) flame retardants. Neurotoxicology (2007) 2.07
Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment. Crit Rev Toxicol (2008) 1.93
Polybrominated diphenyl ether (PBDE) flame retardants: environmental contamination, human body burden and potential adverse health effects. Acta Biomed (2008) 1.54
Expression of human paraoxonase (PON1) during development. Pharmacogenetics (2003) 1.40
Effects of perinatal exposure to a polybrominated diphenyl ether (PBDE 99) on mouse neurobehavioural development. Neurotoxicology (2002) 1.39
Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism. Pharmacogenet Genomics (2005) 1.30
Polybrominated diphenyl ethers: neurobehavioral effects following developmental exposure. Neurotoxicology (2003) 1.25
Neurotoxicity of pesticides: a brief review. Front Biosci (2008) 1.24
Pharmacological and dietary modulators of paraoxonase 1 (PON1) activity and expression: the hunt goes on. Biochem Pharmacol (2010) 1.14
Activation of NMDA receptors induces protein kinase A-mediated phosphorylation and degradation of matrin 3. Blocking these effects prevents NMDA-induced neuronal death. J Neurochem (2005) 1.11
Neurotoxicity of a polybrominated diphenyl ether mixture (DE-71) in mouse neurons and astrocytes is modulated by intracellular glutathione levels. Toxicol Appl Pharmacol (2008) 1.10
Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency. Toxicol Appl Pharmacol (2006) 1.07
Paraoxonase 1 (PON1) modulates the toxicity of mixed organophosphorus compounds. Toxicol Appl Pharmacol (2009) 1.06
Differential in vitro neurotoxicity of the flame retardant PBDE-99 and of the PCB Aroclor 1254 in human astrocytoma cells. Toxicol Lett (2004) 1.05
Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants. Neurotoxicology (2005) 1.02
Repeated developmental exposure of mice to chlorpyrifos oxon is associated with paraoxonase 1 (PON1)-modulated effects on cerebellar gene expression. Toxicol Sci (2011) 1.02
Modulation of neuritogenesis by astrocyte muscarinic receptors. J Biol Chem (2008) 1.00
Dopamine transporter (SLC6A3) 5' region haplotypes significantly affect transcriptional activity in vitro but are not associated with Parkinson's disease. Pharmacogenet Genomics (2005) 0.99
Determination of paraoxonase 1 status and genotypes at specific polymorphic sites. Curr Protoc Toxicol (2004) 0.99
Paraoxonase 1 (PON1) as a genetic determinant of susceptibility to organophosphate toxicity. Toxicology (2012) 0.99
Glutathione levels modulate domoic acid induced apoptosis in mouse cerebellar granule cells. Toxicol Sci (2007) 0.98
Early developmental exposure to BDE 99 or Aroclor 1254 affects neurobehavioural profile: interference from the administration route. Neurotoxicology (2005) 0.97
Low concentrations of the brominated flame retardants BDE-47 and BDE-99 induce synergistic oxidative stress-mediated neurotoxicity in human neuroblastoma cells. Toxicol In Vitro (2009) 0.95
Shotgun proteomics implicates extracellular matrix proteins and protease systems in neuronal development induced by astrocyte cholinergic stimulation. J Neurochem (2008) 0.92
Cholesterol efflux is differentially regulated in neurons and astrocytes: implications for brain cholesterol homeostasis. Biochim Biophys Acta (2012) 0.92
Ethanol induces cholesterol efflux and up-regulates ATP-binding cassette cholesterol transporters in fetal astrocytes. J Biol Chem (2007) 0.91
Gender difference in the interaction of smoking and monoamine oxidase B intron 13 genotype in Parkinson's disease. Neurotoxicology (2002) 0.91
Is decabromodiphenyl ether (BDE-209) a developmental neurotoxicant? Neurotoxicology (2010) 0.90
Paraoxonase 2 (PON2) in the mouse central nervous system: a neuroprotective role? Toxicol Appl Pharmacol (2011) 0.89
Domoic acid as a developmental neurotoxin. Neurotoxicology (2010) 0.89
Pharmacogenomic considerations of the paraoxonase polymorphisms. Pharmacogenomics (2002) 0.88
Effect of organophosphorus insecticides and their metabolites on astroglial cell proliferation. Toxicology (2005) 0.88
Ethanol inhibits muscarinic receptor-induced axonal growth in rat hippocampal neurons. Alcohol Clin Exp Res (2009) 0.88
Mouse cerebellar astrocytes protect cerebellar granule neurons against toxicity of the polybrominated diphenyl ether (PBDE) mixture DE-71. Neurotoxicology (2008) 0.87
5' and 3' region variability in the dopamine transporter gene (SLC6A3), pesticide exposure and Parkinson's disease risk: a hypothesis-generating study. Hum Mol Genet (2006) 0.87
In vivo ethanol decreases phosphorylated MAPK and p70S6 kinase in the developing rat brain. Neuroreport (2003) 0.87
Application of in vitro neurotoxicity testing for regulatory purposes: Symposium III summary and research needs. Neurotoxicology (2008) 0.87
The activation of M1 muscarinic receptor signaling induces neuronal differentiation in pyramidal hippocampal neurons. J Pharmacol Exp Ther (2009) 0.85
Measurements of cell death in neuronal and glial cells. Methods Mol Biol (2011) 0.85
An in vitro approach to assess the toxicity of certain food contaminants: methylmercury and polychlorinated biphenyls. Toxicology (2007) 0.85
Role of phospholipase D signaling in ethanol-induced inhibition of carbachol-stimulated DNA synthesis of 1321N1 astrocytoma cells. J Neurochem (2004) 0.84
Developmental neurotoxicity: some old and new issues. ISRN Toxicol (2012) 0.84
Extracts of various species of Epilobium inhibit proliferation of human prostate cells. J Pharm Pharmacol (2003) 0.84
Assessment of glutathione homeostasis. Methods Mol Biol (2011) 0.84
Effect of ethanol on protein kinase Czeta and p70S6 kinase activation by carbachol: a possible mechanism for ethanol-induced inhibition of glial cell proliferation. J Neurochem (2002) 0.83
Antiglycative and neuroprotective activity of colon-derived polyphenol catabolites. Mol Nutr Food Res (2011) 0.83
Protein adducts as biomarkers of exposure to organophosphorus compounds. Toxicology (2012) 0.83
Behavioral Characterization of GCLM-Knockout Mice, a Model for Enhanced Susceptibility to Oxidative Stress. J Toxicol (2011) 0.83
Ethanol inhibits neuritogenesis induced by astrocyte muscarinic receptors. Glia (2010) 0.83
Manganese inhibits the ability of astrocytes to promote neuronal differentiation. Toxicol Appl Pharmacol (2009) 0.82
Modulation of paraoxonase 2 (PON2) in mouse brain by the polyphenol quercetin: a mechanism of neuroprotection? Neurochem Res (2013) 0.82
Primary neurons in culture and neuronal cell lines for in vitro neurotoxicological studies. Methods Mol Biol (2011) 0.82
Chronic exposure to ammonia induces isoform-selective alterations in the intracellular distribution and NMDA receptor-mediated translocation of protein kinase C in cerebellar neurons in culture. J Neurochem (2005) 0.82
Characterization of the effect of Epilobium extracts on human cell proliferation. Pharmacology (2003) 0.82
Evaluation of DNA damage induced by 2 polybrominated diphenyl ether flame retardants (BDE-47 and BDE-209) in SK-N-MC cells. Int J Toxicol (2012) 0.81
Effects of postnatal ethanol exposure at different developmental phases on neurotrophic factors and phosphorylated proteins on signal transductions in rat brain. Neurotoxicol Teratol (2008) 0.81
Retinoic acid isomers up-regulate ATP binding cassette A1 and G1 and cholesterol efflux in rat astrocytes: implications for their therapeutic and teratogenic effects. J Pharmacol Exp Ther (2011) 0.81
Quantification of synaptic structure formation in cocultures of astrocytes and hippocampal neurons. Methods Mol Biol (2011) 0.81
Effects of postnatal ethanol exposure on neurotrophic factors and signal transduction pathways in rat brain. J Appl Toxicol (2008) 0.80
Measurements of neuronal apoptosis. Methods Mol Biol (2011) 0.80
The toxicity of mixtures of specific organophosphate compounds is modulated by paraoxonase 1 status. Adv Exp Med Biol (2010) 0.80
Genotype combinations for monoamine oxidase-B intron 13 polymorphism and dopamine D2 receptor TaqIB polymorphism are associated with ever-smoking status among men. Neurosci Lett (2005) 0.80
Long-term effects of developmental exposure to low doses of PCB 126 and methylmercury. Toxicol Lett (2010) 0.80
Acute ammonia intoxication induces an NMDA receptor-mediated increase in poly(ADP-ribose) polymerase level and NAD metabolism in nuclei of rat brain cells. J Neurochem (2004) 0.79
Characterization of the in vitro transcriptional activity of polymorphic alleles of the human monoamine oxidase-B gene. Neurosci Lett (2005) 0.79
Morphological assessment of neurite outgrowth in hippocampal neuron-astrocyte co-cultures. Curr Protoc Toxicol (2012) 0.78
Paraoxonase-1 and clopidogrel efficacy. Nat Med (2011) 0.78
Disruption of cholesterol homeostasis in the developing brain as a potential mechanism contributing to the developmental neurotoxicity of ethanol: an hypothesis. Med Hypotheses (2005) 0.78
Paraoxonase 1 (PON1) status and risk of insecticide exposure. J Biochem Mol Toxicol (2005) 0.78
Inorganic lead activates the mitogen-activated protein kinase kinase-mitogen-activated protein kinase-p90(RSK) signaling pathway in human astrocytoma cells via a protein kinase C-dependent mechanism. J Pharmacol Exp Ther (2002) 0.78
Neurobehavioral assessment of mice following repeated postnatal exposure to chlorpyrifos-oxon. Neurotoxicol Teratol (2012) 0.78
Assessment of cholesterol homeostasis in astrocytes and neurons. Methods Mol Biol (2011) 0.77
Ethanol impairs muscarinic receptor-induced neuritogenesis in rat hippocampal slices: Role of astrocytes and extracellular matrix proteins. Biochem Pharmacol (2011) 0.77
Sonic hedgehog in Smith-Lemli-Opitz syndrome and tumor development. J Pediatr Hematol Oncol (2008) 0.76
Neurobehavioral assessment of rats exposed to low doses of PCB126 and methyl mercury during development. Environ Toxicol Pharmacol (2007) 0.76
In vitro neurotoxicology: an introduction. Methods Mol Biol (2011) 0.76
Measurements of astrocyte proliferation. Methods Mol Biol (2011) 0.76
In vitro assessment of mutagenicity and clastogenicity of BDE-99, a pentabrominated diphenyl ether flame retardant. Environ Mol Mutagen (2003) 0.76
Ethanol inhibits muscarinic receptor-mediated DNA synthesis and signal transduction in human fetal astrocytes. Neurosci Lett (2003) 0.76
Low-level domoic acid protects mouse cerebellar granule neurons from acute neurotoxicity: role of glutathione. Toxicol Sci (2013) 0.75
Muscarinic receptor-activated signal transduction pathways involved in the neuritogenic effect of astrocytes in hippocampal neurons. Eur J Pharmacol (2011) 0.75
Developmental neurotoxicity of toluene: in vivo and in vitro effects on astroglial cells. Dev Neurosci (2003) 0.75
Correspondence re: Navas-Acien et al., Interactive effect of chemical substances and occupational electromagnetic field exposure on the risk of gliomas and meningiomas in Swedish men. 11:1678-1683, 2002. Cancer Epidemiol Biomarkers Prev (2003) 0.75
Synaptic structure quantification in cultured neurons. Curr Protoc Toxicol (2014) 0.75
DNA sequence analysis of monoamine oxidase B gene coding and promoter regions in Parkinson's disease cases and unrelated controls. Mov Disord (2004) 0.75