Published in J Chem Inf Model on December 01, 2009
Structures of YAP protein domains reveal promising targets for development of new cancer drugs. Semin Cell Dev Biol (2012) 1.19
Molecular basis of the binding of YAP transcriptional regulator to the ErbB4 receptor tyrosine kinase. Biochimie (2014) 0.81
Tumor-reducing effect of the clinically used drug clofazimine in a SCID mouse model of pancreatic ductal adenocarcinoma. Oncotarget (2017) 0.78
The SCHOOL of nature: III. From mechanistic understanding to novel therapies. Self Nonself (2010) 0.77
Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy. Genes (Basel) (2016) 0.75
Docking analysis of verteporfin with YAP WW domain. Bioinformation (2017) 0.75
SLiMFinder: a probabilistic method for identifying over-represented, convergently evolved, short linear motifs in proteins. PLoS One (2007) 2.55
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet (2012) 2.53
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet (2010) 2.15
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Am J Hum Genet (2009) 2.04
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet (2012) 1.96
CompariMotif: quick and easy comparisons of sequence motifs. Bioinformatics (2008) 1.82
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet (2013) 1.72
Bioinformatic discovery of novel bioactive peptides. Nat Chem Biol (2007) 1.72
SLiMDisc: short, linear motif discovery, correcting for common evolutionary descent. Nucleic Acids Res (2006) 1.61
Blood pressure loci identified with a gene-centric array. Am J Hum Genet (2011) 1.44
A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder. Hum Genet (2011) 1.43
SLiMSearch 2.0: biological context for short linear motifs in proteins. Nucleic Acids Res (2011) 1.23
Structures of YAP protein domains reveal promising targets for development of new cancer drugs. Semin Cell Dev Biol (2012) 1.19
Wrapping up BLAST and other applications for use on Unix clusters. Bioinformatics (2003) 1.17
Masking residues using context-specific evolutionary conservation significantly improves short linear motif discovery. Bioinformatics (2009) 1.17
Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a). J Lipid Res (2012) 1.17
Tandem repeat copy-number variation in protein-coding regions of human genes. Genome Biol (2005) 1.16
The SLiMDisc server: short, linear motif discovery in proteins. Nucleic Acids Res (2007) 1.16
Significantly different patterns of amino acid replacement after gene duplication as compared to after speciation. Mol Biol Evol (2003) 1.16
Prediction of short linear protein binding regions. J Mol Biol (2011) 1.14
Human tissue profiling with multidimensional protein identification technology. J Proteome Res (2005) 1.07
SLiMPrints: conservation-based discovery of functional motif fingerprints in intrinsically disordered protein regions. Nucleic Acids Res (2012) 1.04
Interactome-wide prediction of short, disordered protein interaction motifs in humans. Mol Biosyst (2011) 1.03
SLiMFinder: a web server to find novel, significantly over-represented, short protein motifs. Nucleic Acids Res (2010) 1.02
GASP: Gapped Ancestral Sequence Prediction for proteins. BMC Bioinformatics (2004) 1.01
A genome-wide association study of recipient genotype and medium-term kidney allograft function. Clin Transplant (2013) 1.00
Computational identification and analysis of protein short linear motifs. Front Biosci (Landmark Ed) (2010) 1.00
Approved drug mimics of short peptide ligands from protein interaction motifs. J Chem Inf Model (2008) 0.98
Insider access: pepducin symposium explores a new approach to GPCR modulation. Ann N Y Acad Sci (2009) 0.96
Estimation and efficient computation of the true probability of recurrence of short linear protein sequence motifs in unrelated proteins. BMC Bioinformatics (2010) 0.95
Predicting the important enzymes in human breast milk digestion. J Agric Food Chem (2014) 0.92
BADASP: predicting functional specificity in protein families using ancestral sequences. Bioinformatics (2005) 0.91
Optimal stepwise experimental design for pairwise functional interaction studies. Bioinformatics (2008) 0.90
Towards the improved discovery and design of functional peptides: common features of diverse classes permit generalized prediction of bioactivity. PLoS One (2012) 0.89
Polymorphisms of the Flavin containing monooxygenase 3 (FMO3) gene do not predispose to essential hypertension in Caucasians. BMC Med Genet (2005) 0.88
Meta-analysis to test the association of HIV-1 nef amino acid differences and deletions with disease progression. J Virol (2010) 0.88
Predicting binding within disordered protein regions to structurally characterised peptide-binding domains. PLoS One (2013) 0.87
EnzymePredictor: a tool for predicting and visualizing enzymatic cleavages of digested proteins. J Proteome Res (2012) 0.85
Tools for the identification of variable and potentially variable tandem repeats. BMC Genomics (2006) 0.84
Marked variability in the extent of protein disorder within and between viral families. PLoS One (2013) 0.84
Profile-based short linear protein motif discovery. BMC Bioinformatics (2012) 0.83
Evolution of the isoelectric point of mammalian proteins as a consequence of indels and adaptive evolution. Proteins (2011) 0.83
Protein disorder and short conserved motifs in disordered regions are enriched near the cytoplasmic side of single-pass transmembrane proteins. PLoS One (2012) 0.83
Peptide-binding domains: are limp handshakes safest? Sci Signal (2012) 0.83
Following the digestion of milk proteins from mother to baby. J Proteome Res (2014) 0.82
Platelet glycoprotein Ib alpha receptor polymorphisms and recurrent ischaemic events in acute coronary syndrome patients. J Thromb Thrombolysis (2002) 0.82
Genetic stratification of pathogen-response-related and other variants within a homogeneous Caucasian Irish population. Eur J Hum Genet (2005) 0.82
The impact of genetic variation in the region of the GPIIIa gene, on Pl expression bias and GPIIb/IIIa receptor density in platelets. Br J Haematol (2006) 0.81
Ligand switching in cell-permeable peptides: manipulation of the alpha-integrin signature motif. ACS Chem Biol (2009) 0.81
Elevated white cell count in acute coronary syndromes: relationship to variants in inflammatory and thrombotic genes. BMC Med Genet (2004) 0.81
CycloPs: generating virtual libraries of cyclized and constrained peptides including nonnatural amino acids. J Chem Inf Model (2011) 0.81
Uroplakin III is not a major candidate gene for primary vesicoureteral reflux. Eur J Hum Genet (2005) 0.81
CPPpred: prediction of cell penetrating peptides. Bioinformatics (2013) 0.81
Evaluation of whether accelerated protein evolution in chordates has occurred before, after, or simultaneously with gene duplication. Mol Biol Evol (2006) 0.80
Molecular evolution of CXC chemokines and receptors. Trends Immunol (2003) 0.80
Platelet signalling networks: pathway perturbation demonstrates differential sensitivity of ADP secretion and fibrinogen binding. Platelets (2011) 0.79
A polymorphism in ACE2 is associated with a lower risk for fatal cardiovascular events in females: the MORGAM project. J Renin Angiotensin Aldosterone Syst (2011) 0.79
Absolute net charge and the biological activity of oligopeptides. J Chem Inf Model (2006) 0.79
SCL-Epred: a generalised de novo eukaryotic protein subcellular localisation predictor. Amino Acids (2013) 0.79
Association of methylenetetrahydrofolate reductase polymorphism and the risk of squamous cell carcinoma in renal transplant patients. Transplantation (2007) 0.78
Inhibition of dipeptidyl peptidase IV and xanthine oxidase by amino acids and dipeptides. Food Chem (2013) 0.78
Shift in the isoelectric-point of milk proteins as a consequence of adaptive divergence between the milks of mammalian species. Biol Direct (2011) 0.78
Improved database searches for orthologous sequences by conditioning on outgroup sequences. Bioinformatics (2002) 0.78
Marked variation in predicted and observed variability of tandem repeat loci across the human genome. BMC Genomics (2008) 0.78
SLiMScape: a protein short linear motif analysis plugin for Cytoscape. BMC Bioinformatics (2013) 0.78
Overdispersion of allele frequency differences between populations: implications for meta-analyses of genotypic disease associations. Eur J Hum Genet (2005) 0.77
Cytochrome P450-catalyzed degradation of nicotine: fundamental parameters determining hydroxylation by cytochrome P450 2A6 at the 5'-carbon or the n-methyl carbon. J Phys Chem B (2012) 0.77
PeptideLocator: prediction of bioactive peptides in protein sequences. Bioinformatics (2013) 0.77
Biochemical characterization of Plasmodium falciparum CTP:phosphoethanolamine cytidylyltransferase shows that only one of the two cytidylyltransferase domains is active. Biochem J (2013) 0.77
Differences in the number of intrinsically disordered regions between yeast duplicated proteins, and their relationship with functional divergence. PLoS One (2011) 0.76
Distinct configurations of protein complexes and biochemical pathways revealed by epistatic interaction network motifs. BMC Syst Biol (2011) 0.75
A sequence sub-sampling algorithm increases the power to detect distant homologues. Nucleic Acids Res (2005) 0.75
Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. J Clin Invest (2017) 0.75
Identification of potential small molecule peptidomimetics similar to motifs in proteins. J Chem Inf Model (2007) 0.75
Correlation of disorder between S. cerevisiae interacting proteins. Mol Biosyst (2011) 0.75
Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nat Genet (2017) 0.75
Web server to identify similarity of amino acid motifs to compounds (SAAMCO). J Chem Inf Model (2008) 0.75
In silico protein motif discovery and structural analysis. Methods Mol Biol (2011) 0.75
Computational approaches to developing short cyclic peptide modulators of protein-protein interactions. Methods Mol Biol (2015) 0.75