Torben F Orntoft

Author PubWeight™ 67.60‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH. N Engl J Med 2003 4.88
2 Identifying distinct classes of bladder carcinoma using microarrays. Nat Genet 2002 3.82
3 Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer. Clin Cancer Res 2009 3.08
4 Molecular staging for survival prediction of colorectal cancer patients. J Clin Oncol 2005 2.88
5 Genomic profiling of microRNAs in bladder cancer: miR-129 is associated with poor outcome and promotes cell death in vitro. Cancer Res 2009 2.80
6 Preferential response of cancer cells to zebularine. Cancer Cell 2004 2.39
7 A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition. Nat Genet 2006 2.33
8 Alternative splicing in colon, bladder, and prostate cancer identified by exon array analysis. Mol Cell Proteomics 2008 2.24
9 Emmprin and survivin predict response and survival following cisplatin-containing chemotherapy in patients with advanced bladder cancer. Clin Cancer Res 2007 1.87
10 Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2'-deoxycytidine. Cancer Res 2002 1.71
11 Gene expression signatures predict outcome in non-muscle-invasive bladder carcinoma: a multicenter validation study. Clin Cancer Res 2007 1.68
12 Identification and validation of highly frequent CpG island hypermethylation in colorectal adenomas and carcinomas. Int J Cancer 2011 1.65
13 Comprehensive genome methylation analysis in bladder cancer: identification and validation of novel methylated genes and application of these as urinary tumor markers. Clin Cancer Res 2011 1.46
14 Impact of alterations affecting the p53 pathway in bladder cancer on clinical outcome, assessed by conventional and array-based methods. Clin Cancer Res 2002 1.44
15 DNA copy-number alterations underlie gene expression differences between microsatellite stable and unstable colorectal cancers. Clin Cancer Res 2008 1.44
16 Evaluation of two commercial global miRNA expression profiling platforms for detection of less abundant miRNAs. BMC Genomics 2011 1.39
17 Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells. Diabetes 2009 1.39
18 High-density single nucleotide polymorphism array defines novel stage and location-dependent allelic imbalances in human bladder tumors. Cancer Res 2005 1.34
19 Allelic imbalances in human bladder cancer: genome-wide detection with high-density single-nucleotide polymorphism arrays. J Natl Cancer Inst 2002 1.34
20 DNA methylation signatures for prediction of biochemical recurrence after radical prostatectomy of clinically localized prostate cancer. J Clin Oncol 2013 1.30
21 A molecular signature in superficial bladder carcinoma predicts clinical outcome. Clin Cancer Res 2005 1.28
22 Distinct expression profile in fumarate-hydratase-deficient uterine fibroids. Hum Mol Genet 2005 1.26
23 The resistance of B-CLL cells to DNA damage-induced apoptosis defined by DNA microarrays. Blood 2003 1.24
24 Lysophosphatidylcholine acyltransferase 1 (LPCAT1) overexpression in human colorectal cancer. J Mol Med (Berl) 2008 1.16
25 Candidate driver genes in microsatellite-unstable colorectal cancer. Int J Cancer 2011 1.08
26 Carbonic anhydrase IX is highly expressed in hereditary nonpolyposis colorectal cancer. Cancer Epidemiol Biomarkers Prev 2007 1.00
27 Proteome profiling of corneal epithelium and identification of marker proteins for keratoconus, a pilot study. Exp Eye Res 2005 0.99
28 A 3-plex methylation assay combined with the FGFR3 mutation assay sensitively detects recurrent bladder cancer in voided urine. Clin Cancer Res 2013 0.99
29 Major contribution from recurrent alterations and MSH6 mutations in the Danish Lynch syndrome population. Fam Cancer 2008 0.97
30 The association between genetic variants in hMLH1 and hMSH2 and the development of sporadic colorectal cancer in the Danish population. BMC Med Genet 2008 0.97
31 Germline fumarate hydratase mutations in patients with ovarian mucinous cystadenoma. Eur J Hum Genet 2006 0.97
32 Isolation of microarray-grade total RNA, microRNA, and DNA from a single PAXgene blood RNA tube. J Mol Diagn 2007 0.96
33 EXO1 variants occur commonly in normal population: evidence against a role in hereditary nonpolyposis colorectal cancer. Cancer Res 2003 0.94
34 Clusterin expression can be modulated by changes in TCF1-mediated Wnt signaling. J Mol Signal 2007 0.92
35 Identification of a core set of genes that signifies pathways underlying cardiac hypertrophy. Comp Funct Genomics 2004 0.92
36 Autocrine stimulation by osteopontin plays a pivotal role in the expression of the mitogenic and invasive phenotype of RET/PTC-transformed thyroid cells. Oncogene 2004 0.92
37 Differentiating alternative splice variant patterns of human telomerase reverse transcriptase in thyroid neoplasms. Thyroid 2008 0.92
38 Identification of the genes up- and down-regulated by the high mobility group A1 (HMGA1) proteins: tissue specificity of the HMGA1-dependent gene regulation. Cancer Res 2004 0.91
39 Profiling of circulating microRNAs for prostate cancer biomarker discovery. Drug Deliv Transl Res 2014 0.91
40 Increased expression of transcription factor TFAP2α correlates with chemosensitivity in advanced bladder cancer. BMC Cancer 2011 0.90
41 Increased cell motility and invasion upon knockdown of lipolysis stimulated lipoprotein receptor (LSR) in SW780 bladder cancer cells. BMC Med Genomics 2008 0.89
42 Expression profiling confirms the role of endocytic receptor megalin in renal vitamin D3 metabolism. Kidney Int 2002 0.87
43 Down-modulation of poly(ADP-ribose) polymerase-1 (PARP-1) in human TUR leukemia cells restores transcriptional responsiveness for differentiation and cell cycle arrest. Eur J Cell Biol 2005 0.83
44 Combinations of urinary biomarkers for surveillance of patients with incident nonmuscle invasive bladder cancer: the European FP7 UROMOL project. J Urol 2012 0.82
45 Selection of microsatellite markers for bladder cancer diagnosis without the need for corresponding blood. PLoS One 2012 0.77
46 Gene expression changes induced by bismuth in a macrophage cell line. Cell Tissue Res 2005 0.77
47 Concomitant heterochromatinisation and down-regulation of gene expression unveils epigenetic silencing of RELB in an aggressive subset of chronic lymphocytic leukemia in males. BMC Med Genomics 2010 0.76
48 Bioinformatic identification of FGF, p38-MAPK, and calcium signalling pathways associated with carcinoma in situ in the urinary bladder. BMC Cancer 2008 0.75
49 Mutation analysis of MYH11 in acute myeloid leukemia. Leuk Lymphoma 2008 0.75
50 Transcriptional profile of Ki-Ras-induced transformation of thyroid cells. Cancer Invest 2007 0.75