| Rank | Title | Journal | Year | PubWeight™‹?› |
|---|---|---|---|---|
| 1 | Reductive activation of the prodrug 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2-[[1-(4-nitrophenyl)ethoxy]carbonyl]hydrazine (KS119) selectively occurs in oxygen-deficient cells and overcomes O(6)-alkylguanine-DNA alkyltransferase mediated KS119 tumor cell resistance. | Biochem Pharmacol | 2009 | 0.97 |
| 2 | Selective and brain-permeable polo-like kinase-2 (Plk-2) inhibitors that reduce α-synuclein phosphorylation in rat brain. | ChemMedChem | 2013 | 0.87 |
| 3 | Design and synthesis of highly selective, orally active Polo-like kinase-2 (Plk-2) inhibitors. | Bioorg Med Chem Lett | 2013 | 0.77 |
| 4 | Structure-based design of novel dihydroisoquinoline BACE-1 inhibitors that do not engage the catalytic aspartates. | Bioorg Med Chem Lett | 2013 | 0.76 |
| 5 | Design and synthesis of thiophene dihydroisoquinolines as novel BACE1 inhibitors. | Bioorg Med Chem Lett | 2013 | 0.76 |