| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
|
Nat Genet
|
2013
|
9.46
|
|
2
|
A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease.
|
Neurology
|
2009
|
5.94
|
|
3
|
Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial.
|
Neurology
|
2005
|
5.51
|
|
4
|
The boundary shift integral: an accurate and robust measure of cerebral volume changes from registered repeat MRI.
|
IEEE Trans Med Imaging
|
1997
|
3.94
|
|
5
|
Conversion of amyloid positive and negative MCI to AD over 3 years: an 11C-PIB PET study.
|
Neurology
|
2009
|
3.49
|
|
6
|
Patterns of temporal lobe atrophy in semantic dementia and Alzheimer's disease.
|
Ann Neurol
|
2001
|
3.43
|
|
7
|
Global and local gray matter loss in mild cognitive impairment and Alzheimer's disease.
|
Neuroimage
|
2004
|
3.25
|
|
8
|
Interactive algorithms for the segmentation and quantitation of 3-D MRI brain scans.
|
Comput Methods Programs Biomed
|
1997
|
2.56
|
|
9
|
Modeling brain deformations in Alzheimer disease by fluid registration of serial 3D MR images.
|
J Comput Assist Tomogr
|
1998
|
2.20
|
|
10
|
Rates of global and regional cerebral atrophy in AD and frontotemporal dementia.
|
Neurology
|
2001
|
2.09
|
|
11
|
Patterns of cortical thinning in the language variants of frontotemporal lobar degeneration.
|
Neurology
|
2009
|
1.95
|
|
12
|
Normalization of cerebral volumes by use of intracranial volume: implications for longitudinal quantitative MR imaging.
|
AJNR Am J Neuroradiol
|
2001
|
1.94
|
|
13
|
Hippocampal atrophy rates in Alzheimer disease: added value over whole brain volume measures.
|
Neurology
|
2009
|
1.88
|
|
14
|
The heritability and genetics of frontotemporal lobar degeneration.
|
Neurology
|
2009
|
1.86
|
|
15
|
Measuring atrophy in Alzheimer disease: a serial MRI study over 6 and 12 months.
|
Neurology
|
2005
|
1.73
|
|
16
|
The effect of APOE genotype on clinical phenotype in Alzheimer disease.
|
Neurology
|
2006
|
1.71
|
|
17
|
Early onset familial Alzheimer's disease: Mutation frequency in 31 families.
|
Neurology
|
2003
|
1.71
|
|
18
|
Automated hippocampal segmentation by regional fluid registration of serial MRI: validation and application in Alzheimer's disease.
|
Neuroimage
|
2001
|
1.71
|
|
19
|
Serial magnetic resonance imaging of cerebral atrophy in preclinical Alzheimer's disease.
|
Lancet
|
1999
|
1.68
|
|
20
|
Clinical features of frontotemporal dementia due to the intronic tau 10(+16) mutation.
|
Neurology
|
2002
|
1.60
|
|
21
|
A comparison of methods for the automated calculation of volumes and atrophy rates in the hippocampus.
|
Neuroimage
|
2008
|
1.40
|
|
22
|
Brain biopsy in dementia.
|
Brain
|
2005
|
1.36
|
|
23
|
Accurate registration of serial 3D MR brain images and its application to visualizing change in neurodegenerative disorders.
|
J Comput Assist Tomogr
|
1996
|
1.36
|
|
24
|
Baseline predictors of rates of hippocampal atrophy in mild cognitive impairment.
|
Neurology
|
2007
|
1.33
|
|
25
|
Quantitative MRI measurement of superior cerebellar peduncle in progressive supranuclear palsy.
|
Neurology
|
2005
|
1.33
|
|
26
|
Haemodialysis and cerebral oedema.
|
Nephron
|
2001
|
1.33
|
|
27
|
Progressive brain atrophy on serial MRI in dementia with Lewy bodies, AD, and vascular dementia.
|
Neurology
|
2001
|
1.32
|
|
28
|
MRS shows abnormalities before symptoms in familial Alzheimer disease.
|
Neurology
|
2006
|
1.28
|
|
29
|
Reduced sample sizes for atrophy outcomes in Alzheimer's disease trials: baseline adjustment.
|
Neurobiol Aging
|
2010
|
1.21
|
|
30
|
Acceleration of cortical thinning in familial Alzheimer's disease.
|
Neurobiol Aging
|
2009
|
1.18
|
|
31
|
MR image texture analysis applied to the diagnosis and tracking of Alzheimer's disease.
|
IEEE Trans Med Imaging
|
1998
|
1.17
|
|
32
|
A volumetric study of hippocampus and amygdala in depressed patients with subjective memory problems.
|
J Neuropsychiatry Clin Neurosci
|
2000
|
1.17
|
|
33
|
Epilepsy presenting as AD: neuroimaging, electroclinical features, and response to treatment.
|
Neurology
|
2002
|
1.17
|
|
34
|
Combining short interval MRI in Alzheimer's disease: Implications for therapeutic trials.
|
J Neurol
|
2006
|
1.16
|
|
35
|
Intracranial volume and Alzheimer disease: evidence against the cerebral reserve hypothesis.
|
Arch Neurol
|
2000
|
1.16
|
|
36
|
Detection of ventricular enlargement in patients at the earliest clinical stage of MS.
|
Neurology
|
2000
|
1.14
|
|
37
|
Onset and progression of pathologic atrophy in Huntington disease: a longitudinal MR imaging study.
|
AJNR Am J Neuroradiol
|
2010
|
1.13
|
|
38
|
Tracking progression in frontotemporal lobar degeneration: serial MRI in semantic dementia.
|
Neurology
|
2008
|
1.12
|
|
39
|
Baseline CSF p-tau levels independently predict progression of hippocampal atrophy in Alzheimer disease.
|
Neurology
|
2009
|
1.10
|
|
40
|
Pitfalls in the use of voxel-based morphometry as a biomarker: examples from huntington disease.
|
AJNR Am J Neuroradiol
|
2009
|
1.10
|
|
41
|
Measuring disease progression in frontotemporal lobar degeneration: a clinical and MRI study.
|
Neurology
|
2010
|
1.09
|
|
42
|
Incomplete penetrance of familial Alzheimer's disease in a pedigree with a novel presenilin-1 gene mutation.
|
Lancet
|
1996
|
1.07
|
|
43
|
Whole-brain atrophy rate in Alzheimer disease: identifying fast progressors.
|
Neurology
|
2008
|
1.05
|
|
44
|
Increased hippocampal atrophy rates in AD over 6 months using serial MR imaging.
|
Neurobiol Aging
|
2007
|
1.01
|
|
45
|
Improved reliability of hippocampal atrophy rate measurement in mild cognitive impairment using fluid registration.
|
Neuroimage
|
2006
|
1.01
|
|
46
|
Increased rate of whole-brain atrophy over 6 months in early Huntington disease.
|
Neurology
|
2006
|
1.00
|
|
47
|
Automatic calculation of hippocampal atrophy rates using a hippocampal template and the boundary shift integral.
|
Neurobiol Aging
|
2006
|
0.99
|
|
48
|
Cerebrospinal fluid S100B correlates with brain atrophy in Alzheimer's disease.
|
Neurosci Lett
|
2003
|
0.99
|
|
49
|
Longitudinal imaging in dementia.
|
Br J Radiol
|
2007
|
0.96
|
|
50
|
Progressive ventricular enlargement in patients with clinically isolated syndromes is associated with the early development of multiple sclerosis.
|
J Neurol Neurosurg Psychiatry
|
2002
|
0.96
|
|
51
|
EFNS task force: the use of neuroimaging in the diagnosis of dementia.
|
Eur J Neurol
|
2012
|
0.95
|
|
52
|
Presenilin-1 mutation (E280G), spastic paraparesis, and cranial MRI white-matter abnormalities.
|
Neurology
|
2002
|
0.95
|
|
53
|
Neuropsychological correlates of whole brain atrophy in Alzheimer's disease.
|
Neuropsychologia
|
2008
|
0.95
|
|
54
|
A presenilin 1 R278I mutation presenting with language impairment.
|
Neurology
|
2004
|
0.94
|
|
55
|
The application of serial MRI analysis techniques to the study of cerebral atrophy in late-onset dementia.
|
Med Image Anal
|
2004
|
0.93
|
|
56
|
Neuroimaging tools to rate regional atrophy, subcortical cerebrovascular disease, and regional cerebral blood flow and metabolism: consensus paper of the EADC.
|
J Neurol Neurosurg Psychiatry
|
2003
|
0.93
|
|
57
|
Development of selective verbal memory impairment secondary to a left thalamic infarct: a longitudinal case study.
|
J Neurol Neurosurg Psychiatry
|
2003
|
0.92
|
|
58
|
Magnetization transfer ratio in Alzheimer disease: comparison with volumetric measurements.
|
AJNR Am J Neuroradiol
|
2007
|
0.90
|
|
59
|
Vulnerability to neuroleptic side effects in frontotemporal lobar degeneration.
|
Int J Geriatr Psychiatry
|
2003
|
0.90
|
|
60
|
Mapping the onset and progression of atrophy in familial frontotemporal lobar degeneration.
|
J Neurol Neurosurg Psychiatry
|
2005
|
0.88
|
|
61
|
A decade of pre-diagnostic assessment in a case of familial Alzheimer's disease: tracking progression from asymptomatic to MCI and dementia.
|
Neurocase
|
2005
|
0.87
|
|
62
|
Can the frontal assessment battery (FAB) differentiate bradykinetic rigid syndromes? Relation of the FAB to formal neuropsychological testing.
|
Neurocase
|
2005
|
0.87
|
|
63
|
Chromosome 14 familial Alzheimer's disease: the clinical and neuropathological characteristics of a family with a leucine-->serine (L250S) substitution at codon 250 of the presenilin 1 gene.
|
J Neurol Neurosurg Psychiatry
|
1998
|
0.86
|
|
64
|
Comparison of nasal pressure support ventilation with nasal intermittent positive pressure ventilation in patients with nocturnal hypoventilation.
|
Eur Respir J
|
1993
|
0.84
|
|
65
|
Distinct neuropsychological profiles correspond to distribution of cortical thinning in inherited prion disease caused by insertional mutation.
|
J Neurol Neurosurg Psychiatry
|
2011
|
0.83
|
|
66
|
Missense SNP of the MC1R gene is associated with plumage variation in the Gyrfalcon (Falco rusticolus).
|
Anim Genet
|
2011
|
0.83
|
|
67
|
Brain-water diffusion coefficients reflect the severity of inherited prion disease.
|
Neurology
|
2010
|
0.83
|
|
68
|
Transient ischaemic attacks are associated with increased rates of global cerebral atrophy.
|
J Neurol Neurosurg Psychiatry
|
2003
|
0.82
|
|
69
|
Clinical features of sporadic and familial Alzheimer's disease.
|
Neurodegeneration
|
1996
|
0.82
|
|
70
|
Alzheimer's disease due to an intronic presenilin-1 (PSEN1 intron 4) mutation: A clinicopathological study.
|
Brain
|
2000
|
0.82
|
|
71
|
Pathogenic presenilin 1 mutations (P436S & I143F) in early-onset Alzheimer's disease in the UK. Mutations in brief no. 223. Online.
|
Hum Mutat
|
1999
|
0.82
|
|
72
|
Autopsy-confirmed familial early-onset Alzheimer disease caused by the l153V presenilin 1 mutation.
|
Arch Neurol
|
2001
|
0.82
|
|
73
|
Slowing the progression of Alzheimer disease: monitoring progression.
|
Alzheimer Dis Assoc Disord
|
1997
|
0.81
|
|
74
|
A second family with familial AD and the V717L APP mutation has a later age at onset.
|
Neurology
|
2006
|
0.81
|
|
75
|
Memory complaints and increased rates of brain atrophy: risk factors for mild cognitive impairment and Alzheimer's disease.
|
Int J Geriatr Psychiatry
|
2010
|
0.81
|
|
76
|
CANDID--Counselling and Diagnosis in Dementia: a national telemedicine service supporting the care of younger patients with dementia.
|
Int J Geriatr Psychiatry
|
1998
|
0.80
|
|
77
|
Pathological substrate for regional distribution of increased atrophy rates in progressive supranuclear palsy.
|
J Neurol Neurosurg Psychiatry
|
2004
|
0.78
|
|
78
|
Familial Alzheimer's disease and inherited prion disease in the UK are poorly ascertained.
|
J Neurol Neurosurg Psychiatry
|
2010
|
0.78
|
|
79
|
Do symptoms of memory impairment correspond to cognitive impairment: a cross sectional study of a clinical cohort.
|
Int J Geriatr Psychiatry
|
2006
|
0.76
|
|
80
|
An alternative method for estimating efficacy of the AN1792 vaccine for Alzheimer disease.
|
Neurology
|
2008
|
0.76
|
|
81
|
Presymptomatic studies in genetic frontotemporal dementia.
|
Rev Neurol (Paris)
|
2013
|
0.76
|
|
82
|
An unbiased, staged, multicentre, validation strategy for Alzheimer's disease CSF tau levels.
|
Exp Neurol
|
2009
|
0.76
|
|
83
|
Genetics of the dementias.
|
J Neurol Neurosurg Psychiatry
|
2002
|
0.75
|
|
84
|
The cultural context of visual hallucinations.
|
Postgrad Med J
|
2008
|
0.75
|
|
85
|
Mere forgetfulness or early Alzheimer's disease?
|
Ann Neurol
|
2000
|
0.75
|
|
86
|
Knight's move thinking? Mild cognitive impairment in a chess player.
|
Neurocase
|
2005
|
0.75
|
|
87
|
Non-Alzheimer dementias in young patients.
|
Br J Psychiatry
|
1996
|
0.75
|
|
88
|
Visualisation and quantification of HIV related brain atrophy using registered serial magnetic resonance imaging.
|
Sex Transm Infect
|
1998
|
0.75
|
|
89
|
Application of current ultrastructural eggshell quality assessment in captive breeding programmes: observations on hatched and unhatched eggs of the Saker falcon (Falco cherrug).
|
Br Poult Sci
|
1999
|
0.75
|
|
90
|
Seeing what Alzheimer saw--with magnetic resonance microscopy.
|
Nat Med
|
2000
|
0.75
|
|
91
|
Bacteriological, haematological and clinical chemical studies on the Mauritius kestrel (Falco punctatus).
|
Avian Pathol
|
1986
|
0.75
|