PubRank

Ralph A Defronzo

Author PubWeight™ 42.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects. Diabetes 2008 2.76
2 Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects. Gastroenterology 2007 2.50
3 Plasma ceramides are elevated in obese subjects with type 2 diabetes and correlate with the severity of insulin resistance. Diabetes 2008 2.42
4 Role of sodium-glucose cotransporter 2 (SGLT 2) inhibitors in the treatment of type 2 diabetes. Endocr Rev 2011 2.23
5 Circulating fibroblast growth factor-21 is elevated in impaired glucose tolerance and type 2 diabetes and correlates with muscle and hepatic insulin resistance. Diabetes Care 2009 2.15
6 One-hour plasma glucose concentration and the metabolic syndrome identify subjects at high risk for future type 2 diabetes. Diabetes Care 2008 2.13
7 Dose-response effect of elevated plasma free fatty acid on insulin signaling. Diabetes 2005 1.96
8 Bromocriptine: a sympatholytic, d2-dopamine agonist for the treatment of type 2 diabetes. Diabetes Care 2011 1.38
9 The insulin resistance syndrome: physiological considerations. Diab Vasc Dis Res 2007 1.32
10 Effect of acute physiological hyperinsulinemia on gene expression in human skeletal muscle in vivo. Am J Physiol Endocrinol Metab 2008 1.17
11 Effect of short-term free Fatty acids elevation on mitochondrial function in skeletal muscle of healthy individuals. J Clin Endocrinol Metab 2009 1.13
12 Minimal contribution of fasting hyperglycemia to the incidence of type 2 diabetes in subjects with normal 2-h plasma glucose. Diabetes Care 2009 1.11
13 Glucagon dose-response curve for hepatic glucose production and glucose disposal in type 2 diabetic patients and normal individuals. Metabolism 2002 1.10
14 Metabolic and molecular basis of insulin resistance. J Nucl Cardiol 2003 1.09
15 Adipocytes in subjects with impaired fasting glucose and impaired glucose tolerance are resistant to the anti-lipolytic effect of insulin. Acta Diabetol 2008 1.07
16 AMP-activated protein kinase: Role in metabolism and therapeutic implications. Diabetes Obes Metab 2006 1.07
17 The shape of plasma glucose concentration curve during OGTT predicts future risk of type 2 diabetes. Diabetes Metab Res Rev 2010 1.05
18 Muscle glucose transport and phosphorylation in type 2 diabetic, obese nondiabetic, and genetically predisposed individuals. Am J Physiol Endocrinol Metab 2006 1.05
19 The relationship between {beta}-cell function and glycated hemoglobin: results from the veterans administration genetic epidemiology study. Diabetes Care 2011 1.03
20 Efficacy and safety of Technosphere inhaled insulin compared with Technosphere powder placebo in insulin-naive type 2 diabetes suboptimally controlled with oral agents. Diabetes Care 2008 0.97
21 Pioglitazone improves glucose metabolism and modulates skeletal muscle TIMP-3-TACE dyad in type 2 diabetes mellitus: a randomised, double-blind, placebo-controlled, mechanistic study. Diabetologia 2013 0.95
22 The effect of rosiglitazone on the liver: decreased gluconeogenesis in patients with type 2 diabetes. J Clin Endocrinol Metab 2005 0.91
23 Parental transmission of type 2 diabetes mellitus in a highly endogamous population. World J Diabetes 2013 0.89
24 Effect of a sustained reduction in plasma free fatty acid concentration on insulin signalling and inflammation in skeletal muscle from human subjects. J Physiol 2013 0.87
25 Two-step approach for the prediction of future type 2 diabetes risk. Diabetes Care 2011 0.84
26 Genetic disruption of SOD1 gene causes glucose intolerance and impairs β-cell function. Diabetes 2013 0.83
27 Role of glycated hemoglobin in the prediction of future risk of T2DM. J Clin Endocrinol Metab 2011 0.82
28 Short-term exercise training improves insulin sensitivity but does not inhibit inflammatory pathways in immune cells from insulin-resistant subjects. J Diabetes Res 2013 0.81
29 Pioglitazone improvement of fasting and postprandial hyperglycaemia in Mexican-American patients with Type 2 diabetes: a double tracer OGTT study. Clin Endocrinol (Oxf) 2010 0.80
30 Elevated concentrations of liver enzymes and ferritin identify a new phenotype of insulin resistance: effect of weight loss after gastric banding. Obes Surg 2008 0.79
31 Genetic epidemiology of cardiometabolic risk factors and their clustering patterns in Mexican American children and adolescents: the SAFARI Study. Hum Genet 2013 0.79
32 First approved inhaled insulin therapy for diabetes mellitus. Expert Opin Drug Deliv 2007 0.79
33 Linkage of type 2 diabetes on chromosome 9p24 in Mexican Americans: additional evidence from the Veterans Administration Genetic Epidemiology Study (VAGES). Hum Hered 2013 0.77
34 β-Adrenergic Responsive Induction of Insulin Resistance in Liver of Aging Rats. Endocr Res 2011 0.76
35 Response to comment. Is incretin-based therapy ready for the care of hospitalized patients with type 2 diabetes? Diabetes Care 2014 0.75