|
1
|
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus.
|
Am J Hum Genet
|
2005
|
4.80
|
|
2
|
Global patterns of cis variation in human cells revealed by high-density allelic expression analysis.
|
Nat Genet
|
2009
|
4.72
|
|
3
|
Identification of common variants associated with human hippocampal and intracranial volumes.
|
Nat Genet
|
2012
|
3.73
|
|
4
|
High dimensional endophenotype ranking in the search for major depression risk genes.
|
Biol Psychiatry
|
2011
|
2.23
|
|
5
|
A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5.
|
Hum Mol Genet
|
2008
|
1.98
|
|
6
|
Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus.
|
Hum Mol Genet
|
2007
|
1.95
|
|
7
|
Genetic variation at the FTO locus influences RBL2 gene expression.
|
Diabetes
|
2009
|
1.91
|
|
8
|
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data.
|
Brain Imaging Behav
|
2014
|
1.90
|
|
9
|
Genome-wide linkage analyses of type 2 diabetes in Mexican Americans: the San Antonio Family Diabetes/Gallbladder Study.
|
Diabetes
|
2005
|
1.72
|
|
10
|
Linkage analysis of glomerular filtration rate in American Indians.
|
Kidney Int
|
2008
|
1.59
|
|
11
|
Mutations in a BTB-Kelch protein, KLHL7, cause autosomal-dominant retinitis pigmentosa.
|
Am J Hum Genet
|
2009
|
1.52
|
|
12
|
A single nucleotide polymorphism in MGEA5 encoding O-GlcNAc-selective N-acetyl-beta-D glucosaminidase is associated with type 2 diabetes in Mexican Americans.
|
Diabetes
|
2005
|
1.52
|
|
13
|
Gene mapping in the 20th and 21st centuries: statistical methods, data analysis, and experimental design. 2000.
|
Hum Biol
|
2009
|
1.46
|
|
14
|
Quantitative trait nucleotide analysis using Bayesian model selection. 2005.
|
Hum Biol
|
2009
|
1.46
|
|
15
|
A kernel of truth: statistical advances in polygenic variance component models for complex human pedigrees.
|
Adv Genet
|
2013
|
1.25
|
|
16
|
Haplotypes of transcription factor 7-like 2 (TCF7L2) gene and its upstream region are associated with type 2 diabetes and age of onset in Mexican Americans.
|
Diabetes
|
2007
|
1.25
|
|
17
|
A bias-ed assessment of the use of SNPs in human complex traits.
|
Curr Opin Genet Dev
|
2002
|
1.24
|
|
18
|
A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).
|
PLoS Genet
|
2013
|
1.15
|
|
19
|
Genetic basis of neurocognitive decline and reduced white-matter integrity in normal human brain aging.
|
Proc Natl Acad Sci U S A
|
2013
|
1.11
|
|
20
|
Genetic basis of variation in carotid artery plaque in the San Antonio Family Heart Study.
|
Stroke
|
2002
|
1.07
|
|
21
|
Genome-wide association scan identifies a risk locus for preeclampsia on 2q14, near the inhibin, beta B gene.
|
PLoS One
|
2012
|
1.05
|
|
22
|
Infantile dilated X-linked cardiomyopathy, G4.5 mutations, altered lipids, and ultrastructural malformations of mitochondria in heart, liver, and skeletal muscle.
|
Lab Invest
|
2002
|
1.03
|
|
23
|
A novel missense mutation in ADRB3 increases risk for type 2 diabetes in a Mexican American family.
|
Diabetes Metab Res Rev
|
2006
|
1.02
|
|
24
|
Mother-to-child transmission of HIV-1: strong association with certain maternal HLA-B alleles independent of viral load implicates innate immune mechanisms.
|
J Acquir Immune Defic Syndr
|
2004
|
1.01
|
|
25
|
Bivariate genetic association of KIAA1797 with heart rate in American Indians: the Strong Heart Family Study.
|
Hum Mol Genet
|
2010
|
1.00
|
|
26
|
PSEUDOMARKER: a powerful program for joint linkage and/or linkage disequilibrium analysis on mixtures of singletons and related individuals.
|
Hum Hered
|
2011
|
0.99
|
|
27
|
Genetic determinants of mitochondrial content.
|
Hum Mol Genet
|
2007
|
0.99
|
|
28
|
Powerful identification of cis-regulatory SNPs in human primary monocytes using allele-specific gene expression.
|
PLoS One
|
2012
|
0.98
|
|
29
|
Transcriptome study of differential expression in schizophrenia.
|
Hum Mol Genet
|
2013
|
0.97
|
|
30
|
Type I error rates in association versus joint linkage/association tests in related individuals.
|
Genet Epidemiol
|
2007
|
0.97
|
|
31
|
Genetic and environmental factors in familial clustering in physical activity.
|
Eur J Epidemiol
|
2008
|
0.97
|
|
32
|
A quantitative trait locus (QTL) on chromosome 6q influences birth weight in two independent family studies.
|
Hum Mol Genet
|
2006
|
0.96
|
|
33
|
Quantitative trait locus on Chromosome 19 for circulating levels of intercellular adhesion molecule-1 in Mexican Americans.
|
Atherosclerosis
|
2006
|
0.94
|
|
34
|
Evidence for a founder effect for pseudoxanthoma elasticum in the Afrikaner population of South Africa.
|
Hum Genet
|
2002
|
0.94
|
|
35
|
Influence of age, sex and genetic factors on the human brain.
|
Brain Imaging Behav
|
2014
|
0.92
|
|
36
|
Radiologic phenotypes in lumbar MR imaging for a gene defect in the COL9A3 gene of type IX collagen.
|
Radiology
|
2003
|
0.91
|
|
37
|
Genetic variation in APOJ, LPL, and TNFRSF10B affects plasma fatty acid distribution in Alaskan Eskimos.
|
Am J Clin Nutr
|
2010
|
0.89
|
|
38
|
Variants in CPT1A, FADS1, and FADS2 are Associated with Higher Levels of Estimated Plasma and Erythrocyte Delta-5 Desaturases in Alaskan Eskimos.
|
Front Genet
|
2012
|
0.89
|
|
39
|
On the statistical properties of family-based association tests in datasets containing both pedigrees and unrelated case-control samples.
|
Eur J Hum Genet
|
2011
|
0.89
|
|
40
|
Genotype×age interaction in human transcriptional ageing.
|
Mech Ageing Dev
|
2012
|
0.88
|
|
41
|
Linkage analysis of albuminuria.
|
J Am Soc Nephrol
|
2009
|
0.88
|
|
42
|
Fasting insulin and obesity-related phenotypes are linked to chromosome 2p: the Strong Heart Family Study.
|
Diabetes
|
2006
|
0.87
|
|
43
|
Genome-wide linkage analysis of pulse pressure in American Indians: the Strong Heart Study.
|
Am J Hypertens
|
2008
|
0.87
|
|
44
|
A quantitative trait loci-specific gene-by-sex interaction on systolic blood pressure among American Indians: the Strong Heart Family Study.
|
Hypertension
|
2006
|
0.87
|
|
45
|
Integrating genomic analysis with the genetic basis of gene expression: preliminary evidence of the identification of causal genes for cardiovascular and metabolic traits related to nutrition in Mexicans.
|
Adv Nutr
|
2012
|
0.87
|
|
46
|
Genetic effects on DNA methylation and its potential relevance for obesity in Mexican Americans.
|
PLoS One
|
2013
|
0.86
|
|
47
|
Utilizing extended pedigree information for discovery and confirmation of copy number variable regions among Mexican Americans.
|
Eur J Hum Genet
|
2012
|
0.85
|
|
48
|
Tissue specificity of genetic regulation of gene expression.
|
Nat Genet
|
2012
|
0.85
|
|
49
|
Genetic factors influence serological measures of common infections.
|
Hum Hered
|
2011
|
0.85
|
|
50
|
Diabetes-specific genetic effects on obesity traits in American Indian populations: the Strong Heart Family Study.
|
BMC Med Genet
|
2008
|
0.85
|
|
51
|
Genetic architecture of carotid artery intima-media thickness in Mexican Americans.
|
Circ Cardiovasc Genet
|
2013
|
0.85
|
|
52
|
Genetic influence on variation in serum uric acid in American Indians: the strong heart family study.
|
Hum Genet
|
2009
|
0.85
|
|
53
|
Social- and behavioral-specific genetic effects on blood pressure traits: the Strong Heart Family Study.
|
Circ Cardiovasc Genet
|
2009
|
0.84
|
|
54
|
Novel associations of nonstructural Loci with paraoxonase activity.
|
J Lipids
|
2012
|
0.83
|
|
55
|
Plasma lipidome is independently associated with variability in metabolic syndrome in Mexican American families.
|
J Lipid Res
|
2014
|
0.82
|
|
56
|
Heritable changes in regional cortical thickness with age.
|
Brain Imaging Behav
|
2014
|
0.82
|
|
57
|
Association of differential gene expression with imatinib mesylate and omacetaxine mepesuccinate toxicity in lymphoblastoid cell lines.
|
BMC Med Genomics
|
2012
|
0.81
|
|
58
|
A QTL for genotype by sex interaction for anthropometric measurements in Alaskan Eskimos (GOCADAN Study) on chromosome 19q12-13.
|
Obesity (Silver Spring)
|
2011
|
0.81
|
|
59
|
Genome-wide linkage analysis of carotid artery lumen diameter: the strong heart family study.
|
Int J Cardiol
|
2013
|
0.81
|
|
60
|
A comprehensive analysis of adiponectin QTLs using SNP association, SNP cis-effects on peripheral blood gene expression and gene expression correlation identified novel metabolic syndrome (MetS) genes with potential role in carcinogenesis and systemic inflammation.
|
BMC Med Genomics
|
2013
|
0.80
|
|
61
|
A novel obesity locus on chromosome 4q: the Strong Heart Family Study.
|
Obesity (Silver Spring)
|
2007
|
0.80
|
|
62
|
Update to Terwilliger and Göring's "Gene mapping in the 20th and 21st centuries" (2000): gene mapping when rare variants are common and common variants are rare.
|
Hum Biol
|
2009
|
0.80
|
|
63
|
Genome-wide scan for serum ghrelin detects linkage on chromosome 1p36 in Hispanic children: results from the Viva La Familia study.
|
Pediatr Res
|
2007
|
0.80
|
|
64
|
Statistical genetic analysis of serological measures of common, chronic infections in Alaska Native participants in the GOCADAN study.
|
Genet Epidemiol
|
2013
|
0.80
|
|
65
|
Linkage analysis of factors underlying insulin resistance: Strong Heart Family Study.
|
Obes Res
|
2005
|
0.79
|
|
66
|
Plasma levels of soluble interleukin 1 receptor accessory protein are reduced in obesity.
|
J Clin Endocrinol Metab
|
2014
|
0.79
|
|
67
|
Detection of a quantitative trait locus associated with resistance to Ascaris suum infection in pigs.
|
Int J Parasitol
|
2012
|
0.77
|
|
68
|
Genome-wide genetic and transcriptomic investigation of variation in antibody response to dietary antigens.
|
Genet Epidemiol
|
2014
|
0.77
|
|
69
|
Pleiotropic locus for emotion recognition and amygdala volume identified using univariate and bivariate linkage.
|
Am J Psychiatry
|
2014
|
0.76
|
|
70
|
Novel QTL at chromosome 6p22 for alcohol consumption: Implications for the genetic liability of alcohol use disorders.
|
Am J Med Genet B Neuropsychiatr Genet
|
2014
|
0.76
|
|
71
|
On the validity of the likelihood ratio test and consistency of resulting parameter estimates in joint linkage and linkage disequilibrium analysis under improperly specified parametric models.
|
Ann Hum Genet
|
2011
|
0.75
|
|
72
|
Genetic basis for the increased expression of vacuolar H+ translocating ATPase genes upon imatinib treatment in human lymphoblastoid cells.
|
Cancer Chemother Pharmacol
|
2013
|
0.75
|
|
73
|
Systems genetics of the nuclear factor-κB signal transduction network. I. Detection of several quantitative trait loci potentially relevant to aging.
|
Mech Ageing Dev
|
2011
|
0.75
|
|
74
|
Comparison of strategies for identification of regulatory quantitative trait loci of transcript expression traits.
|
BMC Proc
|
2007
|
0.75
|
|
75
|
Genetic influences of sports participation in Portuguese families.
|
Eur J Sport Sci
|
2013
|
0.75
|