Decreased expression of Fli-1 in bone marrow-derived haematopoietic cells significantly affects disease development in Murphy Roths Large/lymphoproliferation (MRL/lpr) mice.

PubWeight™: 0.88‹?›

🔗 View Article (PMC 2857951)

Published in Clin Exp Immunol on December 15, 2009

Authors

I Molano1, J Mathenia, P Ruiz, G S Gilkeson, X K Zhang

Author Affiliations

1: Department of Medicine, Division of Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC 29425-6370, USA.

Articles cited by this

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature (1992) 12.92

Murine models of systemic lupus erythematosus. Adv Immunol (1985) 9.79

Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1. Genes Dev (1991) 3.54

Systemic lupus erythematosus. N Engl J Med (1994) 3.35

Pathogenesis of systemic lupus erythematosus. J Clin Pathol (2003) 2.93

Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor. Mol Cell Biol (2000) 2.69

Fli-1 is required for murine vascular and megakaryocytic development and is hemizygously deleted in patients with thrombocytopenia. Immunity (2000) 2.59

Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci. J Exp Med (1992) 2.27

Autoreactive B cells in the marginal zone that express dual receptors. J Exp Med (2002) 2.16

Hormonal, environmental, and infectious risk factors for developing systemic lupus erythematosus. Arthritis Rheum (1998) 1.96

Cutting edge: expansion and activation of a population of autoreactive marginal zone B cells in a model of estrogen-induced lupus. J Immunol (2001) 1.75

The ERGB/Fli-1 gene: isolation and characterization of a new member of the family of human ETS transcription factors. Cell Growth Differ (1992) 1.49

An immunological renal disease in transgenic mice that overexpress Fli-1, a member of the ets family of transcription factor genes. Mol Cell Biol (1995) 1.40

Mammalian N-glycan branching protects against innate immune self-recognition and inflammation in autoimmune disease pathogenesis. Immunity (2007) 1.33

FLI1 and EWS-FLI1 function as ternary complex factors and ELK1 and SAP1a function as ternary and quaternary complex factors on the Egr1 promoter serum response elements. Oncogene (1997) 1.27

Complement component C3 is not required for full expression of immune complex glomerulonephritis in MRL/lpr mice. J Immunol (2001) 1.24

Decreased expression of the Ets family transcription factor Fli-1 markedly prolongs survival and significantly reduces renal disease in MRL/lpr mice. J Immunol (2004) 1.24

Organ-specific and systemic autoimmune diseases originate from defects in hematopoietic stem cells. Proc Natl Acad Sci U S A (1990) 1.19

The transcription factor Fli-1 modulates marginal zone and follicular B cell development in mice. J Immunol (2008) 1.16

Expression of ets family of genes in systemic lupus erythematosus and Sjogren's syndrome. Int J Oncol (1996) 1.08

Altered selection processes of B lymphocytes in autoimmune NZB/W mice, despite intact central tolerance against DNA. Eur J Immunol (2001) 0.98

A role for Fli-1 in B cell proliferation: implications for SLE pathogenesis. Clin Immunol (2008) 0.95

Specific inhibition of Egr-1 prevents mesangial cell hypercellularity in experimental nephritis. Kidney Int (2003) 0.86

Expression of the transcriptional regulator Egr-1 in experimental glomerulonephritis: requirement for mesangial cell proliferation. Kidney Int (1997) 0.83

Genetic differences in bone marrow-derived lymphoid lineages control susceptibility to experimental autoimmune myocarditis. J Immunol (2008) 0.80

Articles by these authors

A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency. Immunity (1996) 5.64

The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl-L-arginine. J Exp Med (1994) 2.50

Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci. J Exp Med (1992) 2.27

Induction of plasmacytomas with silicone gel in genetically susceptible strains of mice. J Natl Cancer Inst (1994) 2.24

Dual regulatory role for thyroid-hormone receptors allows control of retinoic-acid receptor activity. Nature (1989) 2.23

Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells. Nat Genet (2000) 2.22

Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA. J Immunol (1991) 2.02

Hormonal, environmental, and infectious risk factors for developing systemic lupus erythematosus. Arthritis Rheum (1998) 1.96

COUP orphan receptors are negative regulators of retinoic acid response pathways. Mol Cell Biol (1992) 1.94

Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway. J Clin Invest (1999) 1.80

Bone marrow transplantation reproduces the tristetraprolin-deficiency syndrome in recombination activating gene-2 (-/-) mice. Evidence that monocyte/macrophage progenitors may be responsible for TNFalpha overproduction. J Clin Invest (1997) 1.78

Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort. Genes Immun (2011) 1.70

High expression level of alpha 6 integrin in human breast carcinoma is correlated with reduced survival. Cancer Res (1995) 1.65

Non-urinary tract infections caused by multiply antibiotic-resistant Corynebacterium urealyticum. Clin Infect Dis (1993) 1.62

E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice. Gastroenterology (2000) 1.57

Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B. J Immunol (2000) 1.55

Differences by race, sex and age in the clinical and immunologic features of recently diagnosed systemic lupus erythematosus patients in the southeastern United States. Lupus (2002) 1.55

Antagonism between retinoic acid receptors and AP-1: implications for tumor promotion and inflammation. New Biol (1991) 1.44

A retinoic acid receptor-specific element controls the retinoic acid receptor-beta promoter. Mol Endocrinol (1990) 1.43

Nephritogenic autoantibodies in lupus: current concepts and continuing controversies. Arthritis Rheum (1996) 1.43

The inductive properties of mesoderm suggest that the neural crest cells are specified by a BMP gradient. Dev Biol (1998) 1.39

The Banff 2007 working classification of skin-containing composite tissue allograft pathology. Am J Transplant (2008) 1.39

[Hyperoxia during anesthesia]. Rev Esp Anestesiol Reanim (2007) 1.38

Prostate-specific antigen in the assessment of organ donors. Transplant Proc (2003) 1.38

ELISA for quantitation of L-selectin shed from leukocytes in vivo. J Immunol Methods (1992) 1.32

Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines. Mol Cell Biol (1998) 1.30

Increased expression of the ETS-related transcription factor FLI-1/ERGB correlates with and can induce the megakaryocytic phenotype. Cell Growth Differ (1996) 1.30

Long-term survival of nonhuman primate islets implanted in an omental pouch on a biodegradable scaffold. Am J Transplant (2009) 1.29

Long-term survival and function of intrahepatic islet allografts in baboons treated with humanized anti-CD154. Diabetes (1999) 1.25

Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations. Genes Immun (2009) 1.25

Neovascularization and the appearance of morphological characteristics of the blood-brain barrier in the embryonic mouse central nervous system. Brain Res Dev Brain Res (1993) 1.24

Complement component C3 is not required for full expression of immune complex glomerulonephritis in MRL/lpr mice. J Immunol (2001) 1.24

Impaired function of macrophage Fc gamma receptors and bacterial infection in alcoholic cirrhosis. N Engl J Med (1994) 1.24

Formation of retinoid X receptor homodimers leads to repression of T3 response: hormonal cross talk by ligand-induced squelching. Mol Cell Biol (1993) 1.22

Genomic view of systemic autoimmunity in MRLlpr mice. Genes Immun (2006) 1.18

Evaluation of new GenoType MTBDRplus for detection of resistance in cultures and direct specimens of Mycobacterium tuberculosis. Int J Tuberc Lung Dis (2008) 1.18

Nuclear retinoic acid receptors: cloning, analysis, and function. Methods Enzymol (1990) 1.17

Interaction of BAG-1 with retinoic acid receptor and its inhibition of retinoic acid-induced apoptosis in cancer cells. J Biol Chem (1998) 1.17

Orphan receptor COUP-TF is required for induction of retinoic acid receptor beta, growth inhibition, and apoptosis by retinoic acid in cancer cells. Mol Cell Biol (2000) 1.17

A role for immunogenic DNA in the pathogenesis of systemic lupus erythematosus. Arthritis Rheum (1990) 1.17

Increased expression of blood mononuclear cell nitric oxide synthase type 2 in rheumatoid arthritis patients. J Exp Med (1996) 1.16

The human estrogen receptor has transcriptional activator and repressor functions in the absence of ligand. New Biol (1990) 1.16

Evaluation of the GenoType Mycobacteria Direct assay for detection of Mycobacterium tuberculosis complex and four atypical mycobacterial species in clinical samples. J Clin Microbiol (2006) 1.16

RAR gamma 2 expression is regulated through a retinoic acid response element embedded in Sp1 sites. Mol Cell Biol (1992) 1.15

Genetic associations of LYN with systemic lupus erythematosus. Genes Immun (2009) 1.15

Correlation of retinoid binding affinity to retinoic acid receptor alpha with retinoid inhibition of growth of estrogen receptor-positive MCF-7 mammary carcinoma cells. Cancer Res (1995) 1.14

Connective tissue growth factor is a biomarker and mediator of kidney allograft fibrosis. Am J Transplant (2006) 1.14

Treatment advances for cocaine-induced ischemic stroke: focus on dihydropyridine-class calcium channel antagonists. Am J Psychiatry (2001) 1.13

Age of onset as a discriminator between alcoholic subtypes in a treatment-seeking outpatient population. Am J Addict (2000) 1.12

Interleukin-7 expression during mouse thymus development. Eur J Immunol (1992) 1.12

Diagnostic imaging of lipoma arborescens. Skeletal Radiol (1998) 1.12

Genomic expression profiling of human inflammatory cardiomyopathy (DCMi) suggests novel therapeutic targets. J Mol Med (Berl) (2006) 1.12

Clinical and serologic manifestations of autoimmune disease in MRL-lpr/lpr mice lacking nitric oxide synthase type 2. J Exp Med (1997) 1.11

Diagnosis of intraocular lymphoma by flow cytometry. Am J Ophthalmol (1997) 1.10

Inhibition of trans-retinoic acid-resistant human breast cancer cell growth by retinoid X receptor-selective retinoids. Mol Cell Biol (1997) 1.09

A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus. Genes Immun (2012) 1.08

Transplantation of umbilical cord mesenchymal stem cells alleviates lupus nephritis in MRL/lpr mice. Lupus (2010) 1.08

Role of MYH9 and APOL1 in African and non-African populations with lupus nephritis. Genes Immun (2011) 1.07

Identification of new SLE-associated genes with a two-step Bayesian study design. Genes Immun (2009) 1.07

Molecular signatures and new candidates to target the pathogenesis of rheumatoid arthritis. Physiol Genomics (2010) 1.07

Circulating levels of plasminogen activator inhibitor type-1, tissue plasminogen activator, and thrombomodulin in hemodialysis patients: biochemical correlations and role as independent predictors of coronary artery stenosis. J Am Soc Nephrol (2001) 1.07

Aerobic hydrogen production by the heterocystous cyanobacteria Anabaena spp. strains CA and 1F. J Bacteriol (1983) 1.06

Thrombocytopenia in HIV-infected drug users in the HAART era. Platelets (2001) 1.05

Banff schema for grading pancreas allograft rejection: working proposal by a multi-disciplinary international consensus panel. Am J Transplant (2008) 1.05

Prospective measure of serum 3-nitrotyrosine levels in systemic lupus erythematosus: correlation with disease activity. Proc Assoc Am Physicians (2000) 1.04

Chronic rejection of mouse kidney allografts. Kidney Int (1999) 1.02

Heterodimeric receptor complexes determine 3,5,3'-triiodothyronine and retinoid signaling specificities. Mol Endocrinol (1992) 1.02

Inhibition of estrogen receptor activity by the tumor promoter 12-O-tetradeconylphorbol-13-acetate: a molecular analysis. Mol Endocrinol (1991) 1.02

A retinoic acid response element that overlaps an estrogen response element mediates multihormonal sensitivity in transcriptional activation of the lactoferrin gene. Mol Cell Biol (1995) 1.02

Purification and characterization of chitosanase and Exo-beta-D-glucosaminidase from a Koji mold, Aspergillus oryzae IAM2660. Biosci Biotechnol Biochem (2000) 1.01

Discriminant variables between organ donors and nondonors: a post hoc investigation. J Transpl Coord (1999) 1.01

Hypertension and albuminuria in chronic kidney disease mapped to a mouse chromosome 11 locus. Kidney Int (2007) 1.00

Efficacy of lamivudine in controlling hepatitis B virus recurrence after liver transplantation. Transplantation (1998) 1.00

Effect of late modulation of nitric oxide production on murine lupus. Clin Immunol Immunopathol (1997) 0.99

EA-1, a novel adhesion molecule involved in the homing of progenitor T lymphocytes to the thymus. J Cell Biol (1991) 0.99

Association of emergence of HLA antibody and acute rejection in intestinal transplant recipients: a possible evidence of acute humoral sensitization. Transplant Proc (2006) 0.98

Enhanced renal leukotriene production in murine lupus: role of lipoxygenase metabolites. Kidney Int (1991) 0.97

Clinical relevance of contemporary cultural psychiatry. J Nerv Ment Dis (1999) 0.97

Evaluation of C1q genomic region in minority racial groups of lupus. Genes Immun (2009) 0.97

Insulin protein and proliferation in ductal cells in the transplanted pancreas of patients with type 1 diabetes and recurrence of autoimmunity. Diabetologia (2008) 0.97

The down-regulated in adenoma (DRA) gene encodes an intestine-specific membrane glycoprotein. Oncogene (1996) 0.96

MicroRNA signature of intestinal acute cellular rejection in formalin-fixed paraffin-embedded mucosal biopsies. Am J Transplant (2011) 0.96

Systemic lupus erythematosus and genetic variation in the interleukin 1 gene cluster: a population based study in the southeastern United States. Ann Rheum Dis (2004) 0.96

Complement receptor 2 polymorphisms associated with systemic lupus erythematosus modulate alternative splicing. Genes Immun (2009) 0.96

Successful living related liver transplantation in an adult with fulminant hepatic failure. Transplantation (1997) 0.96

Impact of Fli-1 transcription factor on autoantibody and lupus nephritis in NZM2410 mice. Clin Exp Immunol (2010) 0.96

Intestinal transplantation for the treatment of desmoid tumors associated with familial adenomatous polyposis. Surgery (2001) 0.95

High-dose donor bone marrow infusions to enhance allograft survival: the effect of timing. Transplantation (1997) 0.95

The influence of DNA structure on the in vitro stimulation of murine lymphocytes by natural and synthetic polynucleotide antigens. Cell Immunol (1993) 0.94

Multivisceral transplantation for megacystis microcolon intestinal hypoperistalsis syndrome. Transplantation (1999) 0.94

Promising new drugs in the treatment of tuberculosis and mycobacteriosis. J Chemother (1989) 0.94

Genetic control of inflammatory arthritis in congenic lpr mice. Clin Immunol Immunopathol (1989) 0.93