| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Etanercept-induced anti-Jo-1-antibody-positive polymyositis in a patient with rheumatoid arthritis: a case report and review of the literature.
|
Clin Rheumatol
|
2010
|
2.53
|
|
2
|
Transforming growth factor (TGF)-beta1-producing regulatory T cells induce Smad-mediated interleukin 10 secretion that facilitates coordinated immunoregulatory activity and amelioration of TGF-beta1-mediated fibrosis.
|
J Exp Med
|
2003
|
1.81
|
|
3
|
Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis.
|
Arthritis Rheum
|
2009
|
1.69
|
|
4
|
Activated STAT4 has an essential role in Th1 differentiation and proliferation that is independent of its role in the maintenance of IL-12R beta 2 chain expression and signaling.
|
J Immunol
|
2002
|
1.64
|
|
5
|
The RIG-I-like receptor IFIH1/MDA5 is a dermatomyositis-specific autoantigen identified by the anti-CADM-140 antibody.
|
Rheumatology (Oxford)
|
2009
|
1.62
|
|
6
|
Oral anti-CD3 antibody treatment induces regulatory T cells and inhibits the development of atherosclerosis in mice.
|
Circulation
|
2009
|
1.28
|
|
7
|
Anti-aminoacyl-tRNA synthetase antibodies in clinical course prediction of interstitial lung disease complicated with idiopathic inflammatory myopathies.
|
Autoimmunity
|
2006
|
1.27
|
|
8
|
Assessment of chimeric mice with humanized liver as a tool for predicting circulating human metabolites.
|
Drug Metab Pharmacokinet
|
2010
|
1.16
|
|
9
|
DIP2 disco-interacting protein 2 homolog A (Drosophila) is a candidate receptor for follistatin-related protein/follistatin-like 1--analysis of their binding with TGF-β superfamily proteins.
|
FEBS J
|
2010
|
1.10
|
|
10
|
Three groups in the 28 joints for rheumatoid arthritis synovitis--analysis using more than 17,000 assessments in the KURAMA database.
|
PLoS One
|
2013
|
0.98
|
|
11
|
Effects of bosentan, an endothelin receptor antagonist, on bile salt export pump and multidrug resistance-associated protein 2.
|
Biopharm Drug Dispos
|
2007
|
0.98
|
|
12
|
Immunohistochemistry and K-ras sequence of pancreatic carcinosarcoma.
|
Pathol Int
|
2008
|
0.96
|
|
13
|
Characterization of human organic cation transporter 1 (OCT1/SLC22A1)- and OCT2 (SLC22A2)-mediated transport of 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)- 4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide (YM155 monobromide), a novel small molecule survivin suppressant.
|
Drug Metab Dispos
|
2010
|
0.95
|
|
14
|
Follistatin-related protein/follistatin-like 1 evokes an innate immune response via CD14 and toll-like receptor 4.
|
FEBS Lett
|
2012
|
0.95
|
|
15
|
Leukoencephalopathy with cognitive impairment following tocilizumab for the treatment of rheumatoid arthritis (RA).
|
Intern Med
|
2009
|
0.94
|
|
16
|
Acute renal failure due to cholesterol crystal embolism treated with LDL apheresis followed by corticosteroid and candesartan.
|
Clin Exp Nephrol
|
2003
|
0.91
|
|
17
|
Absorption, metabolism and excretion of [(14)C]mirabegron (YM178), a potent and selective β(3)-adrenoceptor agonist, after oral administration to healthy male volunteers.
|
Drug Metab Dispos
|
2012
|
0.91
|
|
18
|
Anti-U1 RNP antibodies in cerebrospinal fluid are associated with central neuropsychiatric manifestations in systemic lupus erythematosus and mixed connective tissue disease.
|
Arthritis Rheum
|
2010
|
0.90
|
|
19
|
Successful treatment of a patient with refractory adult Still's disease by tacrolimus.
|
Mod Rheumatol
|
2007
|
0.88
|
|
20
|
Simultaneous absolute protein quantification of carboxylesterases 1 and 2 in human liver tissue fractions using liquid chromatography-tandem mass spectrometry.
|
Drug Metab Dispos
|
2012
|
0.87
|
|
21
|
Identification of human metabolites of (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a novel If channel inhibitor, and investigation of the transporter-mediated renal and hepatic excretion of these metabolites.
|
Drug Metab Dispos
|
2009
|
0.85
|
|
22
|
Vaccination with autoreactive CD4(+)Th1 clones in lupus-prone MRL/Mp-Fas(lpr/lpr) mice.
|
J Autoimmun
|
2009
|
0.84
|
|
23
|
Utility of P-glycoprotein and organic cation transporter 1 double-transfected LLC-PK1 cells for studying the interaction of YM155 monobromide, novel small-molecule survivin suppressant, with P-glycoprotein.
|
Drug Metab Dispos
|
2011
|
0.84
|
|
24
|
Effects of beta-estradiol and propofol on the 4-methylumbelliferone glucuronidation in recombinant human UGT isozymes 1A1, 1A8 and 1A9.
|
Biopharm Drug Dispos
|
2004
|
0.83
|
|
25
|
Carrier-mediated uptake of 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide (YM155 monobromide), a novel small-molecule survivin suppressant, into human solid tumor and lymphoma cells.
|
Drug Metab Dispos
|
2008
|
0.83
|
|
26
|
Characterization of the renal tubular transport of zonampanel, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist, by human organic anion transporters.
|
Drug Metab Dispos
|
2004
|
0.83
|
|
27
|
Development and validation of LC-MS/MS methods for the determination of mirabegron and its metabolites in human plasma and their application to a clinical pharmacokinetic study.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2012
|
0.83
|
|
28
|
Optimized methods for targeted peptide-based quantification of human uridine 5'-diphosphate-glucuronosyltransferases in biological specimens using liquid chromatography-tandem mass spectrometry.
|
Drug Metab Dispos
|
2014
|
0.83
|
|
29
|
Identification of human cytochrome P450 isoforms and esterases involved in the metabolism of mirabegron, a potent and selective β3-adrenoceptor agonist.
|
Xenobiotica
|
2012
|
0.83
|
|
30
|
Protein quantification of UDP-glucuronosyltransferases 1A1 and 2B7 in human liver microsomes by LC-MS/MS and correlation with glucuronidation activities.
|
Xenobiotica
|
2012
|
0.82
|
|
31
|
In vitro inhibition and induction of human cytochrome P450 enzymes by mirabegron, a potent and selective β3-adrenoceptor agonist.
|
Xenobiotica
|
2012
|
0.82
|
|
32
|
Intestinal absorption mechanism of mirabegron, a potent and selective β₃-adrenoceptor agonist: involvement of human efflux and/or influx transport systems.
|
Mol Pharm
|
2013
|
0.82
|
|
33
|
Involvement of human organic cation transporter 1 in the hepatic uptake of 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide (YM155 monobromide), a novel, small molecule survivin suppressant.
|
Drug Metab Dispos
|
2009
|
0.81
|
|
34
|
In vitro inhibitory effects of non-steroidal antiinflammatory drugs on UDP-glucuronosyltransferase 1A1-catalysed estradiol 3beta-glucuronidation in human liver microsomes.
|
Biopharm Drug Dispos
|
2005
|
0.80
|
|
35
|
A case of antisynthetase syndrome in a rheumatoid arthritis patient with anti-PL-12 antibody following treatment with etanercept.
|
Clin Rheumatol
|
2011
|
0.80
|
|
36
|
Serum lipoprotein(a) level and clinical coronary stenosis progression in patients with myocardial infarction: re-revascularization rate is high in patients with high-Lp(a).
|
Circ J
|
2006
|
0.80
|
|
37
|
Pharmacological profile and clinical efficacy of minodronic acid hydrate as a new therapeutic agent for osteoporosis.
|
Nihon Yakurigaku Zasshi
|
2009
|
0.80
|
|
38
|
In vitro inhibitory effects of non-steroidal anti-inflammatory drugs on 4-methylumbelliferone glucuronidation in recombinant human UDP-glucuronosyltransferase 1A9--potent inhibition by niflumic acid.
|
Biopharm Drug Dispos
|
2006
|
0.80
|
|
39
|
Substrate-dependent modulation of UDP-glucuronosyltransferase 1A1 (UGT1A1) by propofol in recombinant human UGT1A1 and human liver microsomes.
|
Basic Clin Pharmacol Toxicol
|
2007
|
0.80
|
|
40
|
Inhibitory potential of nonsteroidal anti-inflammatory drugs on UDP-glucuronosyltransferase 2B7 in human liver microsomes.
|
Eur J Clin Pharmacol
|
2007
|
0.79
|
|
41
|
Identification of human UDP-glucuronosyltransferase responsible for the glucuronidation of niflumic acid in human liver.
|
Pharm Res
|
2006
|
0.79
|
|
42
|
Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.
|
Drug Metab Dispos
|
2011
|
0.79
|
|
43
|
Application of LC-NMR for characterization of rat urinary metabolites of zonampanel monohydrate (YM872).
|
Chem Pharm Bull (Tokyo)
|
2004
|
0.79
|
|
44
|
Hepatic uptake and excretion of (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a novel if channel inhibitor, in rats and humans.
|
Drug Metab Dispos
|
2008
|
0.79
|
|
45
|
Overexpression of a minimal domain of calpastatin suppresses IL-6 production and Th17 development via reduced NF-κB and increased STAT5 signals.
|
PLoS One
|
2011
|
0.79
|
|
46
|
Different effects of proton pump inhibitors and famotidine on the clopidogrel metabolic activation by recombinant CYP2B6, CYP2C19 and CYP3A4.
|
Xenobiotica
|
2012
|
0.79
|
|
47
|
Relationship between exposure of (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a "funny" if current channel inhibitor, and heart rate reduction in tachycardia-induced beagle dogs.
|
Drug Metab Dispos
|
2009
|
0.79
|
|
48
|
The UDP-glucuronosyltransferase 2B7 isozyme is responsible for gemfibrozil glucuronidation in the human liver.
|
Drug Metab Dispos
|
2007
|
0.79
|
|
49
|
Absorption, metabolism and excretion of darexaban (YM150), a new direct factor Xa inhibitor in humans.
|
Xenobiotica
|
2012
|
0.78
|
|
50
|
Correlation of antinuclear antibody and anti-double-stranded DNA antibody with clinical response to infliximab in patients with rheumatoid arthritis: a retrospective clinical study.
|
Arthritis Res Ther
|
2011
|
0.78
|
|
51
|
Periodic fever and erythema nodosum associated with MDS with trisomy 8: report of two cases and review of the literature.
|
Mod Rheumatol
|
2010
|
0.78
|
|
52
|
Coordinated roles of pregnane X receptor and constitutive androstane receptor in autoinduction of voriconazole metabolism in mice.
|
Antimicrob Agents Chemother
|
2012
|
0.78
|
|
53
|
Contribution of UDP-glucuronosyltransferases 1A9 and 2B7 to the glucuronidation of indomethacin in the human liver.
|
Eur J Clin Pharmacol
|
2007
|
0.77
|
|
54
|
Predominant contribution of UDP-glucuronosyltransferase 2B7 in the glucuronidation of racemic flurbiprofen in the human liver.
|
Drug Metab Dispos
|
2007
|
0.77
|
|
55
|
Human HepaRG Cells can be Cultured in Hanging-drop Plates for Cytochrome P450 Induction and Function Assays.
|
Drug Metab Lett
|
2015
|
0.77
|
|
56
|
Role of organic anion transporters in the pharmacokinetics of zonampanel, an alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist, in rats.
|
Drug Metab Dispos
|
2008
|
0.77
|
|
57
|
Pharmacokinetics, distribution and excretion of YM155 monobromide, a novel small-molecule survivin suppressant, in male and pregnant or lactating female rats.
|
Biopharm Drug Dispos
|
2012
|
0.77
|
|
58
|
Effects of aripiprazole and its active metabolite dehydroaripiprazole on the activities of drug efflux transporters expressed both in the intestine and at the blood-brain barrier.
|
Biopharm Drug Dispos
|
2012
|
0.77
|
|
59
|
Autoimmune autonomic ganglionopathy with Sjögren's syndrome: significance of ganglionic acetylcholine receptor antibody and therapeutic approach.
|
Auton Neurosci
|
2008
|
0.77
|
|
60
|
Conclusive identification of the oxybutynin-hydrolyzing enzyme in human liver.
|
Drug Metab Dispos
|
2012
|
0.76
|
|
61
|
In vitro drug interaction between diflunisal and indomethacin via glucuronidation in humans.
|
Biopharm Drug Dispos
|
2006
|
0.76
|
|
62
|
Time-dependent inhibitory effects of (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(2-oxopropyl)-11,28-dioxa-4-azatricyclo[22.3.1.0(4.9)]octacos-18-ene-2,3,10,16-tetrone (FK1706), a novel nonimmunosuppressive immunophilin ligand, on CYP3A4/5 activity in humans in vivo and in vitro.
|
Drug Metab Dispos
|
2009
|
0.76
|
|
63
|
A surface plasmon resonance sensor on a compact disk-type microfluidic device.
|
J Sep Sci
|
2011
|
0.76
|
|
64
|
Comparison of inhibition potentials of drugs against zidovudine glucuronidation in rat hepatocytes and liver microsomes.
|
Drug Metab Dispos
|
2007
|
0.76
|
|
65
|
Liquid chromatography-electrospray tandem mass spectrometric assay suitable for quantitation of YM155, a novel small-molecule survivin suppressant, in dog plasma.
|
Biomed Chromatogr
|
2008
|
0.76
|
|
66
|
Two cases of late-onset drug-induced lupus erythematosus caused by ticlopidine in elderly men.
|
Mod Rheumatol
|
2010
|
0.76
|
|
67
|
Identification of enzymes responsible for the N-oxidation of darexaban glucuronide, the pharmacologically active metabolite of darexaban, and the glucuronidation of darexaban N-oxides in human liver microsomes.
|
Biol Pharm Bull
|
2012
|
0.75
|
|
68
|
LC determination of YM466, a new factor Xa inhibitor, in rat and dog plasma.
|
J Pharm Biomed Anal
|
2002
|
0.75
|
|
69
|
A liquid chromatographic-tandem mass spectrometric method for the determination of YM466, a novel Factor Xa inhibitor, in rat plasma.
|
J Pharm Biomed Anal
|
2004
|
0.75
|
|
70
|
In vitro experimental system for evaluating inhibitory effect of investigational drugs on P-glycoprotein-mediated transcellular transport of tacrolimus (FK506).
|
Biopharm Drug Dispos
|
2014
|
0.75
|
|
71
|
Clinical value of iodine-123 beta-methyliodophenyl pentadecanoic acid (BMIPP) myocardial single photon emission computed tomography for predicting cardiac death among patients with chronic heart failure.
|
Circ J
|
2003
|
0.75
|
|
72
|
[A case of recurrent gastric cancer successfully treated with S-1 oral administration].
|
Gan To Kagaku Ryoho
|
2015
|
0.75
|
|
73
|
Absorption, distribution, metabolism and excretion of YM466, a novel factor Xa inhibitor, in rats.
|
Biopharm Drug Dispos
|
2004
|
0.75
|
|
74
|
Severe subcutaneous generalized edema in a patient with dermatomyositis.
|
Mod Rheumatol
|
2007
|
0.75
|
|
75
|
Species differences in inhibition potential of nonsteroidal anti-inflammatory drugs against estradiol 3beta-glucuronidation between rats, dogs, and humans.
|
J Pharm Sci
|
2008
|
0.75
|
|
76
|
Omental pseudocyst.
|
Radiat Med
|
2007
|
0.75
|
|
77
|
Functional engraftment of human peripheral T and B cells and sustained production of autoantibodies in NOD/LtSzscid/IL-2Rγ(-/-) mice.
|
Eur J Immunol
|
2014
|
0.75
|
|
78
|
Investigation of long-term retention of unchanged (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide, a novel "funny" If current channel inhibitor, and its metabolites in the eyeball and thoracic aorta of rats.
|
Drug Metab Dispos
|
2009
|
0.75
|
|
79
|
Impact of genetic deficiencies of P-glycoprotein and breast cancer resistance protein on pharmacokinetics of aripiprazole and dehydroaripiprazole.
|
Xenobiotica
|
2014
|
0.75
|
|
80
|
Optimal atrioventricular delay setting determined by QT sensor of implanted DDDR pacemaker.
|
Pacing Clin Electrophysiol
|
2002
|
0.75
|
|
81
|
Changes in evoked QT intervals according to variations in atrioventricular delay and cardiac function in patients with implanted QT-driven DDDR pacemakers.
|
Circ J
|
2003
|
0.75
|
|
82
|
NEFA/nucleobindin-2 is a target autoantigen of the anti-Wa antibody and is associated with transfer RNA.
|
Mod Rheumatol
|
2012
|
0.75
|
|
83
|
Hepatobiliary transport of YM466, a novel factor Xa inhibitor, in rats.
|
Eur J Drug Metab Pharmacokinet
|
2006
|
0.75
|
|
84
|
Pharmacokinetics of YM466, a new factor Xa inhibitor, in rats and dogs.
|
Eur J Drug Metab Pharmacokinet
|
2004
|
0.75
|