Published in Mol Microbiol on December 16, 2009
The mycobacterial Mpa-proteasome unfolds and degrades pupylated substrates by engaging Pup's N-terminus. EMBO J (2010) 1.67
Molecular analysis of the prokaryotic ubiquitin-like protein (Pup) conjugation pathway in Mycobacterium tuberculosis. Mol Microbiol (2010) 1.42
"Depupylation" of prokaryotic ubiquitin-like protein from mycobacterial proteasome substrates. Mol Cell (2010) 1.37
Dop functions as a depupylase in the prokaryotic ubiquitin-like modification pathway. EMBO Rep (2010) 1.27
The Mycobacterium tuberculosis proteasome active site threonine is essential for persistence yet dispensable for replication and resistance to nitric oxide. PLoS Pathog (2010) 1.26
Mycobacterial ubiquitin-like protein ligase PafA follows a two-step reaction pathway with a phosphorylated pup intermediate. J Biol Chem (2010) 1.26
Proteasomes and protein conjugation across domains of life. Nat Rev Microbiol (2011) 1.12
Survival of mycobacteria depends on proteasome-mediated amino acid recycling under nutrient limitation. EMBO J (2014) 1.05
Reconstitution of the Mycobacterium tuberculosis pupylation pathway in Escherichia coli. EMBO Rep (2011) 1.04
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Fate of pup inside the Mycobacterium proteasome studied by in-cell NMR. PLoS One (2013) 0.83
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The pupylation machinery is involved in iron homeostasis by targeting the iron storage protein ferritin. Proc Natl Acad Sci U S A (2016) 0.76
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The mycobacterial Mpa-proteasome unfolds and degrades pupylated substrates by engaging Pup's N-terminus. EMBO J (2010) 1.67
The majority of inducible DNA repair genes in Mycobacterium tuberculosis are induced independently of RecA. Mol Microbiol (2003) 1.63
Control of dual-specificity phosphatase-1 expression in activated macrophages by IL-10. Eur J Immunol (2005) 1.56
A distinct structural region of the prokaryotic ubiquitin-like protein (Pup) is recognized by the N-terminal domain of the proteasomal ATPase Mpa. FEBS Lett (2009) 1.55
Optimal efficiency of ClpAP and ClpXP chaperone-proteases is achieved by architectural symmetry. Structure (2009) 1.55
Streptococcus tigurinus, a novel member of the Streptococcus mitis group, causes invasive infections. J Clin Microbiol (2012) 1.49
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Targeted delivery of an ssrA-tagged substrate by the adaptor protein SspB to its cognate AAA+ protein ClpX. Mol Cell (2003) 1.40
Prokaryotic ubiquitin-like protein (Pup) is coupled to substrates via the side chain of its C-terminal glutamate. J Am Chem Soc (2010) 1.36
Structural basis of enzyme encapsulation into a bacterial nanocompartment. Nat Struct Mol Biol (2008) 1.36
Breaking down the wall: fractionation of mycobacteria. J Microbiol Methods (2006) 1.35
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Controlled destruction: AAA+ ATPases in protein degradation from bacteria to eukaryotes. Curr Opin Struct Biol (2009) 1.32
The functions of OmpATb, a pore-forming protein of Mycobacterium tuberculosis. Mol Microbiol (2002) 1.32
Engineering the rRNA decoding site of eukaryotic cytosolic ribosomes in bacteria. Nucleic Acids Res (2007) 1.30
Dop functions as a depupylase in the prokaryotic ubiquitin-like modification pathway. EMBO Rep (2010) 1.27
Mycobacterial ubiquitin-like protein ligase PafA follows a two-step reaction pathway with a phosphorylated pup intermediate. J Biol Chem (2010) 1.26
The redox state of SECIS binding protein 2 controls its localization and selenocysteine incorporation function. Mol Cell Biol (2006) 1.25
Clp chaperone-proteases: structure and function. Res Microbiol (2009) 1.24
DNA damage induction of recA in Mycobacterium tuberculosis independently of RecA and LexA. Mol Microbiol (2002) 1.23
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Broad-range 16S rRNA gene polymerase chain reaction for diagnosis of culture-negative bacterial infections. Clin Infect Dis (2011) 1.22
Lack of mismatch correction facilitates genome evolution in mycobacteria. Mol Microbiol (2004) 1.21
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Binding of neomycin-class aminoglycoside antibiotics to mutant ribosomes with alterations in the A site of 16S rRNA. Antimicrob Agents Chemother (2006) 1.15
Close geographic association of human neoehrlichiosis and tick populations carrying "Candidatus Neoehrlichia mikurensis" in eastern Switzerland. J Clin Microbiol (2012) 1.14
Rapid molecular detection of tuberculosis. N Engl J Med (2011) 1.12
Identification of apolipoprotein N-acyltransferase (Lnt) in mycobacteria. J Biol Chem (2009) 1.12
Assembly pathway of an AAA+ protein: tracking ClpA and ClpAP complex formation in real time. Biochemistry (2007) 1.10
Antibodies protect against intracellular bacteria by Fc receptor-mediated lysosomal targeting. Proc Natl Acad Sci U S A (2010) 1.07
Activity of the mycobacterial proteasomal ATPase Mpa is reversibly regulated by pupylation. J Biol Chem (2011) 0.99
Tuberculosis vaccine strain Mycobacterium bovis BCG Russia is a natural recA mutant. BMC Microbiol (2008) 0.98
The pupylation pathway and its role in mycobacteria. BMC Biol (2012) 0.97
An intrinsic degradation tag on the ClpA C-terminus regulates the balance of ClpAP complexes with different substrate specificity. J Mol Biol (2008) 0.94
Dissecting the complete lipoprotein biogenesis pathway in Streptomyces scabies. Mol Microbiol (2011) 0.94
Structures of Pup ligase PafA and depupylase Dop from the prokaryotic ubiquitin-like modification pathway. Nat Commun (2012) 0.93
Characterization of the mycobacterial NER system reveals novel functions of the uvrD1 helicase. J Bacteriol (2008) 0.93
Both ATPase domains of ClpA are critical for processing of stable protein structures. J Biol Chem (2009) 0.92
Identification of a Broadly Cross-Reactive Epitope in the Inner Shell of the Norovirus Capsid. PLoS One (2013) 0.92
LspA inactivation in Mycobacterium tuberculosis results in attenuation without affecting phagosome maturation arrest. Microbiology (2008) 0.92
Acquired Resistance to Bedaquiline and Delamanid in Therapy for Tuberculosis. N Engl J Med (2015) 0.92
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Pupylation as a signal for proteasomal degradation in bacteria. Biochim Biophys Acta (2013) 0.89
Characterization of a Mycobacterium tuberculosis mutant deficient in pH-sensing adenylate cyclase Rv1264. Int J Med Microbiol (2006) 0.89
Crystal structure of the complex between prokaryotic ubiquitin-like protein and its ligase PafA. J Am Chem Soc (2013) 0.88
Reemergence of Mycobacterium chimaera in Heater-Cooler Units despite Intensified Cleaning and Disinfection Protocol. Emerg Infect Dis (2016) 0.88
Extracellular HIV-1 Nef increases migration of monocytes. Exp Cell Res (2006) 0.88
Relief from Zmp1-mediated arrest of phagosome maturation is associated with facilitated presentation and enhanced immunogenicity of mycobacterial antigens. Clin Vaccine Immunol (2011) 0.87
The biological and structural characterization of Mycobacterium tuberculosis UvrA provides novel insights into its mechanism of action. Nucleic Acids Res (2011) 0.87
The flexible attachment of the N-domains to the ClpA ring body allows their use on demand. J Mol Biol (2008) 0.86
Intra-oesophageal pH profiles and pharmacokinetics of pantoprazole and esomeprazole: a crossover study in patients with gastro-oesophageal reflux disease. Eur J Gastroenterol Hepatol (2003) 0.86
A mycobacterial smc null mutant is proficient in DNA repair and long-term survival. J Bacteriol (2007) 0.85
Studying chaperone-proteases using a real-time approach based on FRET. J Struct Biol (2009) 0.84
Functional characterization of the Mycobacterium tuberculosis zinc metallopeptidase Zmp1 and identification of potential substrates. Biol Chem (2012) 0.84
Crystal structure of Mycobacterium tuberculosis zinc-dependent metalloprotease-1 (Zmp1), a metalloprotease involved in pathogenicity. J Biol Chem (2011) 0.84
Cloning, expression and characterization of Mycobacterium tuberculosis lipoprotein LprF. Biochem Biophys Res Commun (2009) 0.83
Intersubunit cross-talk in pyridoxal 5'-phosphate synthase, coordinated by the C terminus of the synthase subunit. J Biol Chem (2008) 0.83
Functional analyses of mycobacterial lipoprotein diacylglyceryl transferase and comparative secretome analysis of a mycobacterial lgt mutant. J Bacteriol (2012) 0.82
Involvement of CD252 (CD134L) and IL-2 in the expression of cytotoxic proteins in bacterial- or viral-activated human T cells. J Immunol (2009) 0.82
Characterization of a new AAA+ protein from archaea. J Struct Biol (2006) 0.81
Phenylethyl butyrate enhances the potency of second-line drugs against clinical isolates of Mycobacterium tuberculosis. Antimicrob Agents Chemother (2011) 0.81
Analysis of the intestinal microbiome of a recovered Clostridium difficile patient after fecal transplantation. Digestion (2013) 0.81
Lymph node targeting of BCG vaccines amplifies CD4 and CD8 T-cell responses and protection against Mycobacterium tuberculosis. Vaccine (2012) 0.80
FixK₂, a key regulator in Bradyrhizobium japonicum, is a substrate for the protease ClpAP in vitro. FEBS Lett (2012) 0.79
Heartburn in patients with gastro-oesophageal reflux disease in Germany and Sweden: a study on patients' burden of disease. Pharmacoeconomics (2003) 0.78
Mycobacterium algericum sp. nov., a novel rapidly growing species related to the Mycobacterium terrae complex and associated with goat lung lesions. Int J Syst Evol Microbiol (2010) 0.78
Polyphosphates from Mycobacterium bovis--potent inhibitors of class III adenylate cyclases. FEBS J (2009) 0.78
Non-invasive assessment of upper and lower airway infection and inflammation in CF patients. Pediatr Pulmonol (2014) 0.78
Shock-tube study of the thermal decomposition of CH3CHO and CH3CHO + H reaction. J Phys Chem A (2008) 0.78
The alternating power stroke of a 6-cylinder AAA protease chaperone engine. Mol Cell (2009) 0.77
Dynamics of soluble and cellular inflammatory markers in nasal lavage obtained from cystic fibrosis patients during intravenous antibiotic treatment. BMC Pulm Med (2014) 0.77
Lipoproteins of slow-growing Mycobacteria carry three fatty acids and are N-acylated by apolipoprotein N-acyltransferase BCG_2070c. BMC Microbiol (2013) 0.77
Interaction of Rv1625c, a mycobacterial class IIIa adenylyl cyclase, with a mammalian congener. Mol Microbiol (2005) 0.77
Retracted A β-Lactamase based reporter system for ESX dependent protein translocation in mycobacteria. PLoS One (2012) 0.76
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Efficacy and safety of ciclesonide in the treatment of 24,037 asthmatic patients in routine medical care. Respir Med (2010) 0.75
Possible etiology of improvements in both quality of life and overlapping gastroesophageal reflux disease by proton pump inhibitor treatment in a prospective randomized controlled trial. BMC Gastroenterol (2013) 0.75
Substance P in serum and cerebrospinal fluid of depressed patients: no effect of antidepressant treatment. Psychiatry Res (2005) 0.75
Pupylation-dependent and -independent proteasomal degradation in mycobacteria. Biomol Concepts (2015) 0.75
Reaction of hydrogen atoms with propyne at high temperatures: an experimental and theoretical study. J Phys Chem A (2007) 0.75
Effectiveness and safety of ciclesonide in the treatment of patients with persistent allergic or non-allergic asthma in medical practice (Data from a non-interventional study conducted in Austria). Wien Klin Wochenschr (2014) 0.75
Shock wave study on the thermal unimolecular decomposition of allyl radicals. J Phys Chem A (2005) 0.75
Reaction of OH + NO2: high pressure experiments and falloff analysis. J Phys Chem A (2006) 0.75