Published in Ophthalmology on January 19, 2010
Mitochondrial optic neuropathies - disease mechanisms and therapeutic strategies. Prog Retin Eye Res (2010) 3.58
Efficient mitochondrial biogenesis drives incomplete penetrance in Leber's hereditary optic neuropathy. Brain (2013) 2.08
Optical coherence tomography (OCT): imaging the visual pathway as a model for neurodegeneration. Neurotherapeutics (2011) 1.57
The retina as an early biomarker of neurodegeneration in a rotenone-induced model of Parkinson's disease: evidence for a neuroprotective effect of rosiglitazone in the eye and brain. Acta Neuropathol Commun (2016) 1.46
Mathematically modeling the involvement of axons in Leber's hereditary optic neuropathy. Invest Ophthalmol Vis Sci (2012) 1.01
LHON: Mitochondrial Mutations and More. Curr Genomics (2011) 0.96
Association between retinal nerve fiber layer thickness and abnormalities of vision in people with human immunodeficiency virus infection. Am J Ophthalmol (2012) 0.95
OCT: New perspectives in neuro-ophthalmology. Saudi J Ophthalmol (2014) 0.95
The optic nerve: a "mito-window" on mitochondrial neurodegeneration. Mol Cell Neurosci (2012) 0.95
Leber hereditary optic neuropathy: current perspectives. Clin Ophthalmol (2015) 0.94
Mitochondrial DNA: impacting central and peripheral nervous systems. Neuron (2014) 0.90
[Leber's hereditary optic neuropathy]. Ophthalmologe (2011) 0.88
Characterization of retinal nerve fiber layer thickness changes associated with Leber's hereditary optic neuropathy by optical coherence tomography. Exp Ther Med (2013) 0.87
White matter consequences of retinal receptor and ganglion cell damage. Invest Ophthalmol Vis Sci (2014) 0.86
Idebenone protects against retinal damage and loss of vision in a mouse model of Leber's hereditary optic neuropathy. PLoS One (2012) 0.86
Characterization of macular thickness changes in Leber's hereditary optic neuropathy by optical coherence tomography. BMC Ophthalmol (2014) 0.86
Medical management of hereditary optic neuropathies. Front Neurol (2014) 0.86
Effects of idebenone on color vision in patients with leber hereditary optic neuropathy. J Neuroophthalmol (2013) 0.85
A neurodegenerative perspective on mitochondrial optic neuropathies. Acta Neuropathol (2016) 0.84
Mitochondrial disease heterogeneity: a prognostic challenge. Acta Myol (2014) 0.81
Neuron-specific enolase is elevated in asymptomatic carriers of Leber's hereditary optic neuropathy. Invest Ophthalmol Vis Sci (2012) 0.80
Retinal nerve fibre layer thickness and contrast sensitivity in HIV-infected individuals in South Africa: a case-control study. PLoS One (2013) 0.80
Longitudinal analysis of retinal nerve fiber layer and ganglion cell-inner plexiform layer thickness in ethambutol-induced optic neuropathy. Graefes Arch Clin Exp Ophthalmol (2015) 0.79
Optical coherence tomography findings in spinocerebellar ataxia-3. Eye (Lond) (2013) 0.79
Cigarette toxicity triggers Leber's hereditary optic neuropathy by affecting mtDNA copy number, oxidative phosphorylation and ROS detoxification pathways. Cell Death Dis (2015) 0.77
Multifocal VEP provide electrophysiological evidence of predominant dysfunction of the optic nerve fibers derived from the central retina in Leber's hereditary optic neuropathy. Graefes Arch Clin Exp Ophthalmol (2015) 0.76
Reply: Mitochondrial DNA copy number differentiates the Leber's hereditary optic neuropathy affected individuals from the unaffected mutation carriers. Brain (2015) 0.75
Pathological Confirmation of Optic Neuropathy in Familial Dysautonomia. J Neuropathol Exp Neurol (2017) 0.75
Macular thickness changes in a patient with Leber's hereditary optic neuropathy. BMC Ophthalmol (2015) 0.75
Weighing in on Leber hereditary optic neuropathy: effects of mitochondrial mass. Brain (2014) 0.75
Optical Coherence Tomographic Comparison of Cuban Epidemic and Leber's Hereditary Optic Neuropathy. Neuroophthalmology (2015) 0.75
The Optical Coherence Tomographic Profile of Leber Hereditary Optic Neuropathy. Neuroophthalmology (2016) 0.75
Trauma-Associated Leber Hereditary Optic Neuropathy. Neuroophthalmology (2016) 0.75
Changes in Choroidal Thickness follow the RNFL Changes in Leber's Hereditary Optic Neuropathy. Sci Rep (2016) 0.75
The pattern of retinal ganglion cell dysfunction in Leber hereditary optic neuropathy. Mitochondrion (2017) 0.75
A Review of Mitochondrial Optic Neuropathies: From Inherited to Acquired Forms. J Optom (2016) 0.75
Mitochondrial dysfunction as a cause of optic neuropathies. Prog Retin Eye Res (2004) 3.75
The molecular dissection of mtDNA haplogroup H confirms that the Franco-Cantabrian glacial refuge was a major source for the European gene pool. Am J Hum Genet (2004) 3.51
OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypes. Brain (2007) 3.35
OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion. Brain (2008) 2.57
Laser-assisted subepithelial keratectomy versus epipolis laser in situ keratomileusis for myopia: a meta-analysis of clinical outcomes. Clin Experiment Ophthalmol (2013) 2.47
Clinical expression of Leber hereditary optic neuropathy is affected by the mitochondrial DNA-haplogroup background. Am J Hum Genet (2007) 2.40
Vitrectomy for floaters: prospective efficacy analyses and retrospective safety profile. Retina (2014) 2.39
Drug-related mitochondrial optic neuropathies. J Neuroophthalmol (2013) 2.26
Severe impairment of complex I-driven adenosine triphosphate synthesis in leber hereditary optic neuropathy cybrids. Arch Neurol (2005) 2.17
Use of a support vector machine for keratoconus and subclinical keratoconus detection by topographic and tomographic data. Ophthalmology (2012) 2.16
Mitochondrial optic neuropathies: our travels from bench to bedside and back again. Clin Experiment Ophthalmol (2013) 2.14
Rescue of a mitochondrial deficiency causing Leber Hereditary Optic Neuropathy. Ann Neurol (2002) 2.13
Efficient mitochondrial biogenesis drives incomplete penetrance in Leber's hereditary optic neuropathy. Brain (2013) 2.08
Optic nerve degeneration and mitochondrial dysfunction: genetic and acquired optic neuropathies. Neurochem Int (2002) 2.06
Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors. Proc Natl Acad Sci U S A (2007) 2.01
Retinal nerve fiber layer evaluation by optical coherence tomography in unaffected carriers with Leber's hereditary optic neuropathy mutations. Ophthalmology (2005) 2.01
Haplogroup effects and recombination of mitochondrial DNA: novel clues from the analysis of Leber hereditary optic neuropathy pedigrees. Am J Hum Genet (2006) 1.95
Retinal nerve fiber layer evaluation by optical coherence tomography in Leber's hereditary optic neuropathy. Ophthalmology (2005) 1.88
Vitreomacular adhesion in active and end-stage age-related macular degeneration. Am J Ophthalmol (2009) 1.79
The clinical maze of mitochondrial neurology. Nat Rev Neurol (2013) 1.72
Pilot study of optical coherence tomography measurement of retinal blood flow in retinal and optic nerve diseases. Invest Ophthalmol Vis Sci (2011) 1.71
Mitochondrial DNA haplogroup K is associated with a lower risk of Parkinson's disease in Italians. Eur J Hum Genet (2005) 1.71
Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage. Proc Natl Acad Sci U S A (2005) 1.68
Mitochondrial DNA background modulates the assembly kinetics of OXPHOS complexes in a cellular model of mitochondrial disease. Hum Mol Genet (2008) 1.56
Phenotypic heterogeneity of the 8344A>G mtDNA "MERRF" mutation. Neurology (2013) 1.55
Oestrogens ameliorate mitochondrial dysfunction in Leber's hereditary optic neuropathy. Brain (2010) 1.52
Development of an instrument to assess vision-related quality of life in young children. Am J Ophthalmol (2004) 1.51
Mitochondrial DNA signals of late glacial recolonization of Europe from near eastern refugia. Am J Hum Genet (2012) 1.49
Risk factors for ethambutol optic toxicity. Int Ophthalmol (2009) 1.48
Retinal ganglion cell neurodegeneration in mitochondrial inherited disorders. Biochim Biophys Acta (2009) 1.48
The influence of axial length on retinal nerve fibre layer thickness and optic-disc size measurements by spectral-domain OCT. Br J Ophthalmol (2011) 1.42
Microcystic macular degeneration from optic neuropathy: not inflammatory, not trans-synaptic degeneration. Brain (2013) 1.41
Deficit of in vivo mitochondrial ATP production in OPA1-related dominant optic atrophy. Ann Neurol (2004) 1.40
Retinal nerve fiber layer thickness measurements in rats with spectral domain-optical coherence tomography. Invest Ophthalmol Vis Sci (2012) 1.40
Mitochondrial disorders. Curr Opin Neurol (2007) 1.40
Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III. Cancer Res (2006) 1.39
Idebenone treatment in Leber's hereditary optic neuropathy. Brain (2011) 1.39
Leber's Hereditary Optic Neuropathy. Curr Treat Options Neurol (2011) 1.38
Mouse mtDNA mutant model of Leber hereditary optic neuropathy. Proc Natl Acad Sci U S A (2012) 1.35
Leber's hereditary optic neuropathy (LHON) pathogenic mutations induce mitochondrial-dependent apoptotic death in transmitochondrial cells incubated with galactose medium. J Biol Chem (2002) 1.30
Comparison of 2 laser instruments for measuring axial length. J Cataract Refract Surg (2010) 1.30
Repeatability of automatic measurements by a new Scheimpflug camera combined with Placido topography. J Cataract Refract Surg (2011) 1.27
Extensive investigation of a large Brazilian pedigree of 11778/haplogroup J Leber hereditary optic neuropathy. Am J Ophthalmol (2003) 1.27
New treatments for mitochondrial disease-no time to drop our standards. Nat Rev Neurol (2013) 1.26
Melanopsin retinal ganglion cells are resistant to neurodegeneration in mitochondrial optic neuropathies. Brain (2010) 1.26
Detection and quantification of retinal nerve fiber layer thickness in optic disc edema using stratus OCT. Arch Ophthalmol (2006) 1.26
Perioperative risk factors for posterior ischemic optic neuropathy. J Am Coll Surg (2002) 1.25
Visual system involvement in patients with Friedreich's ataxia. Brain (2008) 1.25
Evidence for a novel x-linked modifier locus for leber hereditary optic neuropathy. Ophthalmic Genet (2008) 1.24
Review: orbital amyloidosis. Ophthal Plast Reconstr Surg (2004) 1.24
Spectral-domain optical coherence tomography for the diagnosis and follow-up of glaucoma. Curr Opin Ophthalmol (2011) 1.23
Retinal nerve fiber layer thickness in nonarteritic anterior ischemic optic neuropathy: OCT characterization of the acute and resolving phases. Graefes Arch Clin Exp Ophthalmol (2008) 1.23
A Comparison between Scheimpflug imaging and optical coherence tomography in measuring corneal thickness. Ophthalmology (2013) 1.20
Patterns of ganglion cell complex and nerve fiber layer loss in nonarteritic ischemic optic neuropathy by Fourier-domain optical coherence tomography. Invest Ophthalmol Vis Sci (2012) 1.19
Anterior segment optical coherence tomography-guided big-bubble technique. Ophthalmology (2012) 1.18
OPA1 links human mitochondrial genome maintenance to mtDNA replication and distribution. Genome Res (2010) 1.17
Thymidine and deoxyuridine accumulate in tissues of patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE). FEBS Lett (2007) 1.16
Repeatability of automatic measurements performed by a dual Scheimpflug analyzer in unoperated and post-refractive surgery eyes. J Cataract Refract Surg (2011) 1.15
Ophthalmologic findings in a large pedigree of 11778/Haplogroup J Leber hereditary optic neuropathy. Am J Ophthalmol (2004) 1.15
Neuro-ophthalmology Safer Than MRI? Ophthalmology (2013) 1.15
Vision function in HIV-infected individuals without retinitis: report of the Studies of Ocular Complications of AIDS Research Group. Am J Ophthalmol (2008) 1.15
Leber's hereditary optic neuropathy with childhood onset. Invest Ophthalmol Vis Sci (2006) 1.14
Effect of EPI-743 on the clinical course of the mitochondrial disease Leber hereditary optic neuropathy. Arch Neurol (2012) 1.12
A comprehensive assessment of the precision and agreement of anterior corneal power measurements obtained using 8 different devices. PLoS One (2012) 1.11
Gastrointestinal dysmotility in mitochondrial neurogastrointestinal encephalomyopathy is caused by mitochondrial DNA depletion. Am J Pathol (2008) 1.11
The effects of idebenone on mitochondrial bioenergetics. Biochim Biophys Acta (2011) 1.10