Published in Circ Cardiovasc Genet on December 01, 2009
Molecular genetic studies of complex phenotypes. Transl Res (2011) 1.95
Strategic approaches to unraveling genetic causes of cardiovascular diseases. Circ Res (2011) 1.31
Molecular genetic and functional characterization implicate muscle-restricted coiled-coil gene (MURC) as a causal gene for familial dilated cardiomyopathy. Circ Cardiovasc Genet (2011) 0.93
Challenges in medical applications of whole exome/genome sequencing discoveries. Trends Cardiovasc Med (2012) 0.88
Electrophysiological Mechanisms of Brugada Syndrome: Insights from Pre-clinical and Clinical Studies. Front Physiol (2016) 0.88
Medical DNA sequencing. Curr Opin Cardiol (2011) 0.86
Causality in genetics: the gradient of genetic effects and back to Koch's postulates of causality. Circ Res (2014) 0.85
Arrhythmogenic cardiomyopathy in a patient with a rare loss-of-function KCNQ1 mutation. J Am Heart Assoc (2015) 0.79
Sequencing your genome: what does it mean? Methodist Debakey Cardiovasc J (2014) 0.79
The Case of "Missing Causal Genes" and the Practice of Medicine: A Sherlock Holmes Approach of Deductive Reasoning. Circ Res (2016) 0.78
DNA sequence variants and the practice of medicine. Curr Opin Cardiol (2010) 0.76
The Bottleneck in Genetic Testing. Circ Res (2015) 0.75
Clinical applications of molecular genetic discoveries. Transl Res (2015) 0.75
Missing heritability of complex diseases: Enlightenment by genetic variants from intermediate phenotypes. Bioessays (2016) 0.75
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
Global variation in copy number in the human genome. Nature (2006) 57.50
Alternative isoform regulation in human tissue transcriptomes. Nature (2008) 52.76
The diploid genome sequence of an individual human. PLoS Biol (2007) 44.80
Paired-end mapping reveals extensive structural variation in the human genome. Science (2007) 30.46
Common genetic variation and human traits. N Engl J Med (2009) 21.03
Genes mirror geography within Europe. Nature (2008) 14.23
DNA replication fidelity. Annu Rev Biochem (2000) 7.29
Population analysis of large copy number variants and hotspots of human genetic disease. Am J Hum Genet (2009) 6.79
Going east: new genetic and archaeological perspectives on the modern human colonization of Eurasia. Science (2006) 4.97
Stratigraphic placement and age of modern humans from Kibish, Ethiopia. Nature (2005) 4.58
A geographically explicit genetic model of worldwide human-settlement history. Am J Hum Genet (2006) 3.81
MicroRNA control of muscle development and disease. Curr Opin Cell Biol (2009) 3.04
Managing DNA polymerases: coordinating DNA replication, DNA repair, and DNA recombination. Proc Natl Acad Sci U S A (2001) 1.78
SCN5A mutations and the role of genetic background in the pathophysiology of Brugada syndrome. Circ Cardiovasc Genet (2009) 1.64
Modifier genes for hypertrophic cardiomyopathy. Curr Opin Cardiol (2002) 1.47
The fidelity of DNA polymerase beta during distributive and processive DNA synthesis. J Biol Chem (1999) 1.46
Genome-wide histone methylation profile for heart failure. Genes Cells (2008) 1.34
Philosophy of science. The Cha-Cha-Cha Theory of Scientific Discovery. Science (2007) 1.10
DNA replication fork proteins. Methods Mol Biol (2009) 0.93
Low incidence of sudden cardiac death in a Swedish Y111C type 1 long-QT syndrome population. Circ Cardiovasc Genet (2009) 0.89
Clinical implications of the "personal" genome. Curr Atheroscler Rep (2008) 0.82
Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy. J Clin Invest (2006) 3.22
Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease. Am J Hum Genet (2009) 2.50
A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels and severity of coronary atherosclerosis. J Am Coll Cardiol (2005) 2.42
Human molecular genetic and functional studies identify TRIM63, encoding Muscle RING Finger Protein 1, as a novel gene for human hypertrophic cardiomyopathy. Circ Res (2012) 2.25
Surprises of the genome and "personalized" medicine. J Am Coll Cardiol (2008) 1.84
Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure, and metabolism. Proc Natl Acad Sci U S A (2003) 1.74
Myozenin 2 is a novel gene for human hypertrophic cardiomyopathy. Circ Res (2007) 1.51
Atorvastatin and cardiac hypertrophy and function in hypertrophic cardiomyopathy: a pilot study. Eur J Clin Invest (2010) 1.47
Differential interactions of thin filament proteins in two cardiac troponin T mouse models of hypertrophic and dilated cardiomyopathies. Cardiovasc Res (2008) 1.33
Resolution of established cardiac hypertrophy and fibrosis and prevention of systolic dysfunction in a transgenic rabbit model of human cardiomyopathy through thiol-sensitive mechanisms. Circulation (2009) 1.30
Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy. Circ Res (2009) 1.28
Genome-wide mapping of modifier chromosomal loci for human hypertrophic cardiomyopathy. Hum Mol Genet (2007) 1.23
The 9p21 susceptibility locus for coronary artery disease and the severity of coronary atherosclerosis. BMC Cardiovasc Disord (2009) 1.18
Regulatable atrial natriuretic peptide gene therapy for hypertension. Proc Natl Acad Sci U S A (2005) 1.09
Metabolomic distinction and insights into the pathogenesis of human primary dilated cardiomyopathy. Eur J Clin Invest (2010) 0.97
Molecular genetic and functional characterization implicate muscle-restricted coiled-coil gene (MURC) as a causal gene for familial dilated cardiomyopathy. Circ Cardiovasc Genet (2011) 0.93
Arrhythmogenic right ventricular cardiomyopathy is a disease of cardiac stem cells. Curr Opin Cardiol (2010) 0.90
Pathogenesis of hypertrophic cardiomyopathy caused by myozenin 2 mutations is independent of calcineurin activity. Cardiovasc Res (2012) 0.90
Phenotypic plasticity of sarcomeric protein mutations. J Am Coll Cardiol (2007) 0.89
Release kinetics of circulating cardiac myosin binding protein-C following cardiac injury. Am J Physiol Heart Circ Physiol (2013) 0.86
Can an energy-deficient heart grow bigger and stronger? J Am Coll Cardiol (2003) 0.80
FAT10 protects cardiac myocytes against apoptosis. J Mol Cell Cardiol (2013) 0.77
Noncoding RNAs in cardiovascular biology and disease. Circ Res (2013) 0.77
Determinants of plasma vitamin D levels in patients with acute coronary syndromes. Eur J Clin Invest (2011) 0.76
DNA sequence variants and the practice of medicine. Curr Opin Cardiol (2010) 0.76
Genome-wide association study of susceptibility alleles for coronary artery disease. Curr Atheroscler Rep (2008) 0.75
Clinical significance of single nucleotide polymorphisms in PCSK9. Curr Atheroscler Rep (2007) 0.75
A novel genetic risk factor for myocardial infarction. Curr Atheroscler Rep (2007) 0.75
Matrix metalloproteinase-I gene variants and risk of myocardial infarction. Curr Atheroscler Rep (2006) 0.75
Interleukin-18 and cardiovascular events. Curr Atheroscler Rep (2006) 0.75
Cholesteryl ester transfer protein TaqIB polymorphism in the cholesterol and recurrent events study. Curr Atheroscler Rep (2005) 0.75
Ali J. Marian: life and science are one. Circ Res (2014) 0.75
Errors in DNA replication and genetic diseases. Curr Opin Cardiol (2013) 0.75
Pharmacogenetic study of statin therapy and cholesterol reduction. Curr Atheroscler Rep (2005) 0.75