Published in Am J Physiol on March 01, 1991
Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity. Drug Metab Rev (2012) 2.76
Continuous versus intermittent portal triad clamping for liver resection: a controlled study. Ann Surg (1999) 2.68
Blockade of Janus kinase-2 signaling ameliorates mouse liver damage due to ischemia and reperfusion. Liver Transpl (2010) 2.30
Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury. J Clin Invest (2005) 2.20
Factors in the pathophysiology of the liver ischemia-reperfusion injury. J Surg Res (2007) 1.89
Role of Kupffer cells in the pathogenesis of liver disease. World J Gastroenterol (2006) 1.84
The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury. J Clin Invest (2005) 1.63
Oxygen radical scavengers selectively inhibit interleukin 8 production in human whole blood. J Clin Invest (1992) 1.52
Molecular mediators of liver ischemia and reperfusion injury: a brief review. Mol Med (2008) 1.43
Current strategies to minimize hepatic ischemia-reperfusion injury by targeting reactive oxygen species. Transplant Rev (Orlando) (2012) 1.38
Role of free radicals in liver diseases. Hepatol Int (2009) 1.36
Hepatocyte signaling through CXC chemokine receptor-2 is detrimental to liver recovery after ischemia/reperfusion in mice. Hepatology (2008) 1.36
Interleukin-37 reduces liver inflammatory injury via effects on hepatocytes and non-parenchymal cells. J Gastroenterol Hepatol (2012) 1.33
Specific role of interleukin-1 in hepatic neutrophil recruitment after ischemia/reperfusion. Am J Pathol (2002) 1.31
Interleukin-33 is hepatoprotective during liver ischemia/reperfusion in mice. Hepatology (2012) 1.21
T-cell immunoglobulin mucin-3 determines severity of liver ischemia/reperfusion injury in mice in a TLR4-dependent manner. Gastroenterology (2010) 1.16
CXC chemokines play a critical role in liver injury, recovery, and regeneration. Am J Surg (2009) 1.16
Mouse model of liver ischemia and reperfusion injury: method for studying reactive oxygen and nitrogen metabolites in vivo. Free Radic Biol Med (2008) 1.13
Sulfatide-mediated activation of type II natural killer T cells prevents hepatic ischemic reperfusion injury in mice. Gastroenterology (2010) 1.13
Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury. J Immunol (2013) 1.11
Innate immune cells in liver inflammation. Mediators Inflamm (2012) 1.11
IL-13 activates STAT6 and inhibits liver injury induced by ischemia/reperfusion. Am J Pathol (1999) 1.11
Inhibition of TNF-α protects against hepatic ischemia-reperfusion injury in rats via NF-κB dependent pathway. Naunyn Schmiedebergs Arch Pharmacol (2012) 1.09
Glutathione protects the rat liver against reperfusion injury after prolonged warm ischemia. Ann Surg (2004) 1.08
Distinct contributions of CD4+ T cell subsets in hepatic ischemia/reperfusion injury. Am J Physiol Gastrointest Liver Physiol (2009) 1.07
The emerging role of T cell immunoglobulin mucin-1 in the mechanism of liver ischemia and reperfusion injury in the mouse. Hepatology (2010) 1.07
Kupffer cell-dependent TNF-alpha signaling mediates injury in the arterialized small-for-size liver transplantation in the mouse. Proc Natl Acad Sci U S A (2006) 1.06
N-acetylcysteine attenuates ischemia-reperfusion-induced apoptosis and autophagy in mouse liver via regulation of the ROS/JNK/Bcl-2 pathway. PLoS One (2014) 1.03
Role of galectin-3 in breast cancer metastasis: involvement of nitric oxide. Am J Pathol (2002) 1.01
Intravenous administration of glutathione protects parenchymal and non-parenchymal liver cells against reperfusion injury following rat liver transplantation. World J Gastroenterol (2004) 1.00
A blockade of complement activation prevents rapid intestinal ischaemia-reperfusion injury by modulating mucosal mast cell degranulation in rats. Clin Exp Immunol (1998) 0.98
The role of neutrophils in the development of liver diseases. Cell Mol Immunol (2014) 0.97
Acute hyperglycemia worsens hepatic ischemia/reperfusion injury in rats. J Gastrointest Surg (2009) 0.96
Nuclear factor {kappa}B inactivation in the rat liver ameliorates short term total warm ischaemia/reperfusion injury. Gut (2005) 0.96
Biomarkers distinguish apoptotic and necrotic cell death during hepatic ischemia/reperfusion injury in mice. Liver Transpl (2014) 0.96
Hepatic ischemia-reperfusion injury: roles of Ca2+ and other intracellular mediators of impaired bile flow and hepatocyte damage. Dig Dis Sci (2006) 0.95
Calcium/calmodulin-dependent protein kinase IV limits organ damage in hepatic ischemia-reperfusion injury through induction of autophagy. Am J Physiol Gastrointest Liver Physiol (2012) 0.95
The protective effect of alpha-tocopherol and GdCl3 against hepatic ischemia/reperfusion injury. Surg Today (2006) 0.95
Reduced inflammatory response and increased microcirculatory disturbances during hepatic ischemia-reperfusion injury in steatotic livers of ob/ob mice. Am J Physiol Gastrointest Liver Physiol (2007) 0.94
Inhibition of COX 1 and 2 prior to renal ischemia/reperfusion injury decreases the development of fibrosis. Mol Med (2008) 0.94
The peptidyl-prolyl isomerase, Pin1, facilitates NF-kappaB binding in hepatocytes and protects against hepatic ischemia/reperfusion injury. J Hepatol (2009) 0.93
Hierarchical and selective roles of galectins in hepatocarcinogenesis, liver fibrosis and inflammation of hepatocellular carcinoma. World J Gastroenterol (2013) 0.92
Hepatocellular protection by nitric oxide or nitrite in ischemia and reperfusion injury. Arch Biochem Biophys (2008) 0.92
Ischemic preconditioning decreases C-X-C chemokine expression and neutrophil accumulation early after liver transplantation in rats. World J Gastroenterol (2003) 0.91
Age-related decrease in proteasome expression contributes to defective nuclear factor-kappaB activation during hepatic ischemia/reperfusion. Hepatology (2009) 0.89
Ischemia-reperfusion injury in rat steatotic liver is dependent on NFκB P65 activation. Transpl Immunol (2012) 0.88
Receptor activator of nuclear factor-κB ligand (RANKL) protects against hepatic ischemia/reperfusion injury in mice. Hepatology (2012) 0.88
The combination of ischemic preconditioning and liver Bcl-2 overexpression is a suitable strategy to prevent liver and lung damage after hepatic ischemia-reperfusion. Am J Pathol (2002) 0.88
Protection of Veratrum nigrum L. var. ussuriense Nakai alkaloids against ischemia-reperfusion injury of the rat liver. World J Gastroenterol (2007) 0.87
Peroxisome proliferator-activated receptors ligands and ischemia-reperfusion injury. Naunyn Schmiedebergs Arch Pharmacol (2007) 0.86
CXC-chemokine regulation and neutrophil trafficking in hepatic ischemia-reperfusion injury in P-selectin/ICAM-1 deficient mice. J Inflamm (Lond) (2007) 0.86
Gender affects reperfusion injury in rat liver. Dig Dis Sci (2001) 0.84
Bucillamine, a thiol antioxidant, prevents transplantation-associated reperfusion injury. Proc Natl Acad Sci U S A (2002) 0.84
SPA0355 attenuates ischemia/reperfusion-induced liver injury in mice. Exp Mol Med (2014) 0.84
Does glyphosate impact on Cu uptake by, and toxicity to, the earthworm Eisenia fetida? Ecotoxicology (2012) 0.84
Pentoxifylline inhibits liver expression of tumor necrosis factor alpha mRNA following normothermic ischemia-reperfusion. HPB (Oxford) (2007) 0.83
Cyclopamine attenuates acute warm ischemia reperfusion injury in cholestatic rat liver: hope for marginal livers. Mol Pharm (2011) 0.83
Serum manganese superoxide dismutase and thioredoxin are potential prognostic markers for hepatitis C virus-related hepatocellular carcinoma. World J Gastroenterol (2011) 0.83
Rapid conversion to high xanthine oxidase activity in viable Kupffer cells during hypoxia. J Clin Invest (1994) 0.83
Myeloperoxidase and elastase are only expressed by neutrophils in normal and in inflamed liver. Histochem Cell Biol (2011) 0.82
Nitrosative and oxidative stresses contribute to post-ischemic liver injury following severe hemorrhagic shock: the role of hypoxemic resuscitation. PLoS One (2012) 0.81
The effect of p38 mitogen-activated protein kinase activation on inflammatory liver damage following hemorrhagic shock in rats. PLoS One (2012) 0.81
Timing of arterialization in liver transplantation. Ann Surg (1994) 0.81
Superimposed traumatic brain injury modulates vasomotor responses in third-order vessels after hemorrhagic shock. Scand J Trauma Resusc Emerg Med (2013) 0.81
Effects of Wy14643 on hepatic ischemia reperfusion injury in rats. World J Gastroenterol (2008) 0.80
Aetiology and risk factors of ischaemic cholangiopathy after liver transplantation. World J Gastroenterol (2014) 0.80
Hepatic sinusoidal endothelium avidly binds platelets in an integrin-dependent manner, leading to platelet and endothelial activation and leukocyte recruitment. Am J Physiol Gastrointest Liver Physiol (2012) 0.80
Roles of hepatocyte and myeloid CXC chemokine receptor-2 in liver recovery and regeneration after ischemia/reperfusion in mice. Hepatology (2013) 0.80
Rapid intestinal ischaemia-reperfusion injury is suppressed in genetically mast cell-deficient Ws/Ws rats. Clin Exp Immunol (1999) 0.80
Critical review of resveratrol in xenobiotic-induced hepatotoxicity. Food Chem Toxicol (2015) 0.80
Divergent roles of superoxide and nitric oxide in liver ischemia and reperfusion injury. J Clin Biochem Nutr (2010) 0.79
Antioxidant Stress and Anti-Inflammation of PPARα on Warm Hepatic Ischemia-Reperfusion Injury. PPAR Res (2012) 0.79
Biliverdin protects against liver ischemia reperfusion injury in swine. PLoS One (2013) 0.79
A spontaneous nitric oxide donor ameliorates small bowel ischemia-reperfusion injury in dogs. Dig Dis Sci (2001) 0.79
Peroxynitrite formation and sinusoidal endothelial cell injury during acetaminophen-induced hepatotoxicity in mice. Comp Hepatol (2004) 0.79
Effect of ischemia reperfusion on rabbit VX2 cells in a hepatocellular carcinoma model. Int J Clin Exp Pathol (2015) 0.79
Resuscitation after hemorrhagic shock: the effect on the liver--a review of experimental data. J Anesth (2012) 0.79
The effect of estrogen on hepatic microcirculation after ischemia/reperfusion. Int J Colorectal Dis (2007) 0.79
Ischemic preconditioning-induced hyperperfusion correlates with hepatoprotection after liver resection. World J Gastroenterol (2010) 0.78
Anti-CD163-dexamethasone protects against apoptosis after ischemia/reperfusion injuries in the rat liver. Ann Med Surg (Lond) (2015) 0.78
Protocol TOP-Study (tacrolimus organ perfusion): a prospective randomized multicenter trial to reduce ischemia reperfusion injury in transplantation of marginal liver grafts with an ex vivo tacrolimus perfusion. Transplant Res (2013) 0.78
Liver transplantation in man: morphometric analysis of the parenchymal alterations following cold ischaemia and warm ischaemia/reperfusion. J Anat (2001) 0.78
Genetic basis of hepatitis virus-associated hepatocellular carcinoma: linkage between infection, inflammation, and tumorigenesis. J Gastroenterol (2016) 0.78
Failure of P-selectin blockade alone to protect the liver from ischemia-reperfusion injury in the isolated blood-perfused rat liver. World J Gastroenterol (2008) 0.78
Expression of intercellular adhesion molecule-1 (ICAM- 1) during ischemia-reperfusion in human liver tissue allograft: image analysis by confocal laser scanning microscopy. Dig Dis Sci (2003) 0.77
Marginal copper deficiency increases liver neutrophil accumulation after ischemia/reperfusion in rats. Biol Trace Elem Res (2010) 0.77
Regulatory mechanisms of injury and repair after hepatic ischemia/reperfusion. Scientifica (Cairo) (2012) 0.77
CD44 disruption attenuates murine hepatic ischemia/reperfusion injury. J Korean Med Sci (2011) 0.77
Role of Hypoxia-Inducible Factors in the Development of Liver Fibrosis. Cell Mol Gastroenterol Hepatol (2015) 0.77
Hepatocyte apoptosis is enhanced after ischemia/reperfusion in the steatotic liver. J Clin Biochem Nutr (2011) 0.77
The protective mechanism of Yisheng Injection against hepatic ischemia reperfusion injury in mice. World J Gastroenterol (2004) 0.77
Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential. Redox Biol (2016) 0.77
Inhibition of warm ischemic injury to rat liver, pancreas, and heart grafts by controlling the nutritional status of both donor and recipient. Surg Today (1997) 0.77
Characterization of microparticles after hepatic ischemia-reperfusion injury. PLoS One (2014) 0.76
Therapeutic targets for cholestatic liver injury. Expert Opin Ther Targets (2015) 0.76
Bucillamine improves hepatic microcirculation and reduces hepatocellular injury after liver warm ischaemia-reperfusion injury. HPB (Oxford) (2009) 0.76
Xenobiotic and Endobiotic Mediated Interactions Between the Cytochrome P450 System and the Inflammatory Response in the Liver. Adv Pharmacol (2015) 0.76
Thyroid hormone-induced cytosol-to-nuclear translocation of rat liver Nrf2 is dependent on Kupffer cell functioning. ScientificWorldJournal (2011) 0.76
Autophagy in the liver: cell's cannibalism and beyond. Arch Pharm Res (2016) 0.76
Role of the Inflammasome in Acetaminophen-induced Liver Injury and Acute Liver Failure. J Hepatol (2016) 0.75
Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: apoptosis or necrosis? Hepatology (2001) 2.74
Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo. FASEB J (1990) 2.41
Activation of caspase 3 (CPP32)-like proteases is essential for TNF-alpha-induced hepatic parenchymal cell apoptosis and neutrophil-mediated necrosis in a murine endotoxin shock model. J Immunol (1998) 1.82
Parenchymal cell apoptosis as a signal for sinusoidal sequestration and transendothelial migration of neutrophils in murine models of endotoxin and Fas-antibody-induced liver injury. Hepatology (1998) 1.80
Neutrophil-induced liver cell injury in endotoxin shock is a CD11b/CD18-dependent mechanism. Am J Physiol (1991) 1.59
The hepatic inflammatory response after acetaminophen overdose: role of neutrophils. Toxicol Sci (2000) 1.52
Functional inactivation of neutrophils with a Mac-1 (CD11b/CD18) monoclonal antibody protects against ischemia-reperfusion injury in rat liver. Hepatology (1993) 1.47
Inhibition of Fas receptor (CD95)-induced hepatic caspase activation and apoptosis by acetaminophen in mice. Toxicol Appl Pharmacol (1999) 1.42
Reactive oxygen species during ischemia-reflow injury in isolated perfused rat liver. J Clin Invest (1988) 1.38
Transcriptional activation of vascular cell adhesion molecule-1 gene in vivo and its role in the pathophysiology of neutrophil-induced liver injury in murine endotoxin shock. J Immunol (1997) 1.27
Glutathione peroxidase-deficient mice are more susceptible to neutrophil-mediated hepatic parenchymal cell injury during endotoxemia: importance of an intracellular oxidant stress. Hepatology (1999) 1.23
Cytokine-induced upregulation of hepatic intercellular adhesion molecule-1 messenger RNA expression and its role in the pathophysiology of murine endotoxin shock and acute liver failure. Hepatology (1995) 1.20
Effects of CXC chemokines on neutrophil activation and sequestration in hepatic vasculature. Am J Physiol Gastrointest Liver Physiol (2001) 1.17
Complement activates Kupffer cells and neutrophils during reperfusion after hepatic ischemia. Am J Physiol (1993) 1.14
Metastases to breast simulating ductal carcinoma in situ: report of two cases and review of the literature. Ann Diagn Pathol (2001) 1.11
Mitochondria and xanthine oxidase both generate reactive oxygen species in isolated perfused rat liver after hypoxic injury. Biochem Biophys Res Commun (1989) 1.06
Sequestration of neutrophils in the hepatic vasculature during endotoxemia is independent of beta 2 integrins and intercellular adhesion molecule-1. Shock (1996) 1.01
Complement and tumor necrosis factor-alpha contribute to Mac-1 (CD11b/CD18) up-regulation and systemic neutrophil activation during endotoxemia in vivo. J Leukoc Biol (1994) 1.00
Activation of Kupffer cells and neutrophils for reactive oxygen formation is responsible for endotoxin-enhanced liver injury after hepatic ischemia. Shock (1995) 1.00
Enhanced sinusoidal glutathione efflux during endotoxin-induced oxidant stress in vivo. Am J Physiol (1992) 0.99
Experimental chronic renal ischemia: morphologic and immunologic studies. Kidney Int (1992) 0.97
Pathophysiologic importance of E- and L-selectin for neutrophil-induced liver injury during endotoxemia in mice. Hepatology (2000) 0.95
Protection against TNF-induced liver parenchymal cell apoptosis during endotoxemia by a novel caspase inhibitor in mice. Toxicol Appl Pharmacol (2000) 0.93
Increased P-selectin gene expression in the liver vasculature and its role in the pathophysiology of neutrophil-induced liver injury in murine endotoxin shock. J Leukoc Biol (1998) 0.93
Role of nitric oxide in the oxidant stress during ischemia/reperfusion injury of the liver. Life Sci (1992) 0.90
Hypoxic damage generates reactive oxygen species in isolated perfused rat liver. Biochem Biophys Res Commun (1988) 0.90
Role of leukotriene B4 in the pathogenesis of hepatic ischemia-reperfusion injury in the rat. Prostaglandins Leukot Essent Fatty Acids (1992) 0.86
Role of PECAM-1 (CD31) in neutrophil transmigration in murine models of liver and peritoneal inflammation. Am J Physiol (1998) 0.83
Inhibition of nitric oxide synthesis aggravates reperfusion injury after hepatic ischemia and endotoxemia. Shock (1995) 0.83
Glutathione disulfide as index of oxidant stress in rat liver during hypoxia. Am J Physiol (1990) 0.82
Beneficial effects of extracellular glutathione against endotoxin-induced liver injury during ischemia and reperfusion. Circ Shock (1994) 0.81
Contribution of complement-stimulated hepatic macrophages and neutrophils to endotoxin-induced liver injury in rats. Hepatology (1994) 0.78
Release of soluble intercellular adhesion molecule 1 into bile and serum in murine endotoxin shock. Hepatology (1996) 0.77
The 21-aminosteroid tirilazad mesylate protects against endotoxin shock and acute liver failure in rats. J Pharmacol Exp Ther (1994) 0.76
Intracytoplasmic lumina in a case of bilaterally multifocal renal oncocytomas. Arch Pathol Lab Med (1994) 0.75
Serum complement mediates endotoxin-induced cysteinyl leukotriene formation in rats in vivo. Am J Physiol (1992) 0.75