PubRank

E Leitersdorf

Author PubWeight™ 64.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mechanism of action of fibrates on lipid and lipoprotein metabolism. Circulation 1998 4.39
2 Premature discontinuation of clinical trial for reasons not related to efficacy, safety, or feasibility. BMJ 2001 2.74
3 Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene. J Biol Chem 1998 1.65
4 Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding. J Biol Chem 2000 1.60
5 Elimination of cholesterol in macrophages and endothelial cells by the sterol 27-hydroxylase mechanism. Comparison with high density lipoprotein-mediated reverse cholesterol transport. J Biol Chem 1997 1.36
6 Evidence for a dominant gene that suppresses hypercholesterolemia in a family with defective low density lipoprotein receptors. J Clin Invest 1989 1.24
7 Differences in hepatic levels of intermediates in bile acid biosynthesis between Cyp27(-/-) mice and CTX. J Lipid Res 2001 1.13
8 Human LDL receptor gene: two ApaLI RFLPs. Nucleic Acids Res 1987 1.09
9 Multiple crm- mutations in familial hypercholesterolemia. Evidence for 13 alleles, including four deletions. J Clin Invest 1988 1.08
10 Taq1B CETP polymorphism, plasma CETP, lipoproteins, apolipoproteins and sex differences in a Jewish population sample characterized by low HDL-cholesterol. Atherosclerosis 2000 1.03
11 A truncated human peroxisome proliferator-activated receptor alpha splice variant with dominant negative activity. Mol Endocrinol 1999 1.00
12 A common Lithuanian mutation causing familial hypercholesterolemia in Ashkenazi Jews. Am J Hum Genet 1991 1.00
13 Verapamil enhances receptor-mediated endocytosis of low density lipoproteins by aortic cells in culture. Arteriosclerosis 1985 1.00
14 Side chain hydroxylations in bile acid biosynthesis catalyzed by CYP3A are markedly up-regulated in Cyp27-/- mice but not in cerebrotendinous xanthomatosis. J Biol Chem 2001 0.99
15 Cholesteryl ester transfer protein (CETP) genetic variation and early onset of non-fatal myocardial infarction. Ann Hum Genet 2008 0.95
16 Phenotypic-genotypic analysis of CYP2C19 in the Jewish Israeli population. Clin Pharmacol Ther 1999 0.94
17 A cholesterol-lowering gene maps to chromosome 13q. Am J Hum Genet 2000 0.93
18 The alpha-defensins stimulate proteoglycan-dependent catabolism of low-density lipoprotein by vascular cells: a new class of inflammatory apolipoprotein and a possible contributor to atherogenesis. Blood 2000 0.91
19 Sterol 27-hydroxylase deficiency: a rare cause of xanthomas in normocholesterolemic humans. Trends Endocrinol Metab 2000 0.91
20 The role of polyunsaturated fatty acids (PUFA) in the treatment of dyslipidemias. Curr Pharm Des 2009 0.89
21 Fenfluramine and mazindol: acute reversible cardiomyopathy associated with their use. Int J Psychiatry Med 1985 0.89
22 Lipoprotein lipase mediated uptake of non-degradable ether analogues of phosphatidylcholine and cholesteryl ester by cultured cells. Biochim Biophys Acta 1984 0.89
23 Hypercholesterolemia in five Israeli Christian-Arab kindreds is caused by the "Lebanese" allele at the low density lipoprotein receptor gene locus and by an additional independent major factor. Hum Genet 1991 0.88
24 Cerebrotendinous xanthomatosis: a family study of sterol 27-hydroxylase mutations and pharmacotherapy. QJM 1996 0.88
25 Recent origin and spread of a common Lithuanian mutation, G197del LDLR, causing familial hypercholesterolemia: positive selection is not always necessary to account for disease incidence among Ashkenazi Jews. Am J Hum Genet 2001 0.87
26 Cerebrotendinous xanthomatosis: molecular diagnosis enables presymptomatic detection of a treatable disease. Neurology 1994 0.87
27 'Danger' effect of low-density lipoprotein (LDL) and oxidized LDL on human immature dendritic cells. Clin Exp Immunol 2007 0.85
28 A nonsense mutation in the LDL receptor gene leads to familial hypercholesterolemia in the Druze sect. Am J Hum Genet 1992 0.85
29 Synthesis and secretion of triacylglycerol lipase by cultured rat hepatocytes. Biochim Biophys Acta 1984 0.85
30 Consensus for the use of fibrates in the treatment of dyslipoproteinemia and coronary heart disease. Fibrate Consensus Group. Am J Cardiol 1998 0.85
31 Molecular genetics of cerebrotendinous xanthomatosis in Jews of north African origin. J Lipid Res 1994 0.85
32 The role of apolipoproteins of HDL in the selective uptake of cholesteryl linoleyl ether by cultured rat and bovine adrenal cells. Biochim Biophys Acta 1986 0.84
33 Molecular genetics of familial hypercholesterolemia in Israel. Hum Genet 1996 0.84
34 The rationale for using HMG-CoA reductase inhibitors ('statins') in peripheral arterial disease. Eur J Vasc Endovasc Surg 2006 0.84
35 Uptake of rat plasma HDL subfractions labeled with [3H]cholesteryl linoleyl ether or with 125I by cultured rat hepatocytes and adrenal cells. Biochim Biophys Acta 1984 0.83
36 The discrete and combined effect of SREBP-2 and SCAP isoforms in the control of plasma lipids among familial hypercholesterolaemia patients. Atherosclerosis 2006 0.82
37 Clinical-biochemical correlation in molecularly characterized patients with Niemann-Pick type C. Genet Med 2001 0.82
38 Identification and properties of the proline664-leucine mutant LDL receptor in South Africans of Indian origin. J Lipid Res 1992 0.82
39 Recurrent apical ballooning despite treatment with verapamil. Cardiology 2006 0.82
40 Identification of two novel LDL receptor gene defects in French-Canadian pediatric population: mutational analysis and biochemical studies. Hum Mutat 1997 0.81
41 Spontaneous rupture of lung echinococcal cyst causing anaphylactic shock and respiratory distress syndrome. Thorax 2006 0.81
42 Clinical and biochemical features, molecular diagnosis and long-term management of a case of cerebrotendinous xanthomatosis. Clin Chim Acta 2001 0.81
43 Premature termination codon at the sterol 27-hydroxylase gene causes cerebrotendinous xanthomatosis in an Afrikaner family. Hum Mol Genet 1994 0.81
44 Erythroderma and pneumonitis induced by penicillin? Respiration 1986 0.80
45 Leucocytoclastic vasculitis and pneumonitis induced by metformin. Br Med J (Clin Res Ed) 1986 0.80
46 The patient at risk: who should we be treating? Br J Clin Pract Suppl 1996 0.80
47 Severe upper airway obstruction and difficult intubation in cicatricial pemphigoid. Anaesthesia 1986 0.80
48 Captopril-associated transient aplastic anemia. Acta Haematol 1985 0.79
49 Transcriptional regulation of the human sterol 27-hydroxylase gene (CYP27) and promoter mapping. Atherosclerosis 2001 0.79
50 Premature termination codon at the sterol 27-hydroxylase gene causes cerebrotendinous xanthomatosis in a French family. Hum Genet 1995 0.79
51 Bulimia. An underlying behavioral disorder in hyperlipidemic pancreatitis: a prospective multidisciplinary approach. Arch Intern Med 1987 0.79
52 The contribution of candidate genes to the response of plasma lipids and lipoproteins to dietary challenge. Atherosclerosis 2000 0.78
53 Atypical ventricular tachycardia in combined tetracyclic, antidepressant, neuroleptic and anticholinergic drugs interaction. Int J Psychiatry Med 1982 0.78
54 Identification of two new LDL-receptor mutations causing homozygous familial hypercholesterolemia in a South African of Indian origin. Biochim Biophys Acta 1993 0.78
55 Metabolism of liposomes prepared from a labelled ether analog of 1,2-dioleoyl-sn-glycero-3-phosphocholine in the rat. Biochim Biophys Acta 1984 0.78
56 Acute bilateral brachial plexus neuritis associated with hypersensitivity vasculitis. A case report and review of literature. Klin Wochenschr 1985 0.78
57 Studies on lipolytic enzymes in cell culture. Monogr Atheroscler 1986 0.77
58 Reversible functional asplenia and subcapsular liver hematoma--two distinctive manifestations of amyloidosis. Klin Wochenschr 1987 0.77
59 Angiotensin II stimulates receptor-mediated uptake of LDL by bovine adrenal cortical cells in primary culture. Biochim Biophys Acta 1985 0.77
60 Expression of lipoprotein lipase mRNA in rat heart is localized mainly to mesenchymal cells as studied by in situ hybridization. Arterioscler Thromb 1991 0.76
61 Plasma lipids and lipoproteins response to a dietary challenge: analysis of four candidate genes. Clin Genet 1995 0.76
62 The modulation of plasma lipids and lipoproteins during bone marrow transplantation is unrelated to exogenously administered recombinant human granulocyte-monocyte colony-stimulating factor (rHu GM-CSF). Med Oncol 1996 0.76
63 Regulation of lipoprotein lipase by dibutyryl cAMP, cholera toxin, Hepes and heparin in F1 heart-cell cultures. Biochim Biophys Acta 1992 0.76
64 Plasmapheresis for streptococcal sepsis? Lancet 1985 0.76
65 Segregation analysis of plasma lipoprotein(a) levels in pedigrees with molecularly defined familial hypercholesterolemia. Genet Epidemiol 1995 0.76
66 Impact of different low-density lipoprotein (LDL) receptor mutations on the ability of LDL to support lymphocyte proliferation. Metabolism 1999 0.76
67 Lactobacillus plantarum endocarditis. Klin Wochenschr 1984 0.75
68 Infective endocarditis in Jerusalem. A comparative analysis of native and prosthetic valve endocarditis. Isr J Med Sci 1983 0.75
69 [Impact of hormone replacement therapy on the cardiovascular system]. Harefuah 1995 0.75
70 [Lipoprotein (a)--a risk factor for atherosclerosis]. Harefuah 1992 0.75
71 Hypothesis: new concepts on the pathogenesis of early prosthetic valve endocarditis. Med Hypotheses 1982 0.75
72 Haplotype analysis at the low density lipoprotein receptor locus: application to the study of familial hypercholesterolemia in Israel. Hum Genet 1992 0.75
73 Preferential uptake of cholesteryl ester-HDL by cultured macrophages. Atherosclerosis 1987 0.75
74 [Can regression of coronary atherosclerosis be induced?]. Harefuah 1995 0.75
75 Analysis of risk factors in 532 survivors of first myocardial infarction hospitalized in Jerusalem. Atherosclerosis 1986 0.75
76 [Triethylene tetramine in Wilson's disease]. Harefuah 1986 0.75
77 Preferential binding of [3H]cholesteryl linoleyl ether-HDL3 by bovine adrenal membranes. Biochim Biophys Acta 1987 0.75
78 Absence of familial defective apolipoprotein B-100 in Israeli patients with dominantly inherited hypercholesterolemia and in offspring with parental history of myocardial infarction. Hum Genet 1993 0.75
79 High-dose fluvastatin and bezafibrate combination treatment for heterozygous familial hypercholesterolemia. Am J Cardiol 1995 0.75
80 Fluvastatin in familial hypercholesterolemia: a cohort analysis of the response to combination treatment. Am J Cardiol 1994 0.75
81 Is "primary" subphrenic abscess caused by Streptococcus milleri a result of unrecognized gastrointestinal perforation? Klin Wochenschr 1986 0.75
82 Maintenance of ambulatory diabetic patients on subcutaneous insulin pump. Isr J Med Sci 1984 0.75
83 [Splenic infarction as an unusual cause of left pleural effusion]. Harefuah 2004 0.75
84 Targeted prevention of coronary artery disease: pharmacological considerations in multimodality treatment. Cardiology 1997 0.75
85 A new method for determination of serum cholestanol by high-performance liquid chromatography with ultraviolet detection. J Chromatogr B Biomed Sci Appl 2000 0.75
86 Influence of apolipoprotein E genotypes on plasma lipid and lipoprotein concentrations: results from a segregation analysis in pedigrees with molecularly defined familial hypercholesterolemia. Genet Epidemiol 1996 0.75
87 Prenatal diagnosis of familial hypercholesterolemia caused by the "Lebanese" mutation at the low density lipoprotein receptor locus. Hum Genet 1992 0.75