Published in Xenotransplantation on December 31, 2009
Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases. Proc Natl Acad Sci U S A (2011) 2.61
Precision editing of large animal genomes. Adv Genet (2012) 1.34
Clinical islet xenotransplantation: how close are we? Diabetes (2012) 1.26
Clinical lung xenotransplantation--what donor genetic modifications may be necessary? Xenotransplantation (2012) 1.16
Completion of the swine genome will simplify the production of swine as a large animal biomedical model. BMC Med Genomics (2012) 1.14
Xenotransplantation--the future of corneal transplantation? Cornea (2011) 1.10
Genetically modified pigs for biomedical research. J Inherit Metab Dis (2012) 1.05
Initial in vitro investigation of the human immune response to corneal cells from genetically engineered pigs. Invest Ophthalmol Vis Sci (2011) 1.01
Infection barriers to successful xenotransplantation focusing on porcine endogenous retroviruses. Clin Microbiol Rev (2012) 0.97
Generation and characterization of human heme oxygenase-1 transgenic pigs. PLoS One (2012) 0.93
New concepts of immune modulation in xenotransplantation. Transplantation (2013) 0.89
Kidney xenotransplantation. Kidney Int (2013) 0.88
Therapeutic issues in the treatment of vascularized xenotransplants using gal-knockout donors in nonhuman primates. Curr Opin Organ Transplant (2011) 0.88
The role of genetically engineered pigs in xenotransplantation research. J Pathol (2015) 0.87
Current progress of genetically engineered pig models for biomedical research. Biores Open Access (2014) 0.84
Reduction in inflammatory gene expression in skeletal muscle from Roux-en-Y gastric bypass patients randomized to omentectomy. PLoS One (2011) 0.82
Efficient production of multi-modified pigs for xenotransplantation by 'combineering', gene stacking and gene editing. Sci Rep (2016) 0.78
Current status of pig kidney xenotransplantation. Int J Surg (2015) 0.77
Constitutive expression of the anti-apoptotic Bcl-2 family member A1 in murine endothelial cells leads to transplant tolerance. Clin Exp Immunol (2017) 0.75
Generation of α-1,3-galactosyltransferase knocked-out transgenic cloned pigs with knocked-in five human genes. Transgenic Res (2016) 0.75
Kidneys From α1,3-Galactosyltransferase Knockout/Human Heme Oxygenase-1/Human A20 Transgenic Pigs Are Protected From Rejection During Ex Vivo Perfusion With Human Blood. Transplant Direct (2015) 0.75
Genetically Modified Pigs as Organ Donors for Xenotransplantation. Mol Biotechnol (2017) 0.75
Generation of CMAHKO/GTKO/shTNFRI-Fc/HO-1 quadruple gene modified pigs. Transgenic Res (2017) 0.75
Gene Editing, Gene Therapy, and Cell Xenotransplantation: Cell Transplantation Across Species. Curr Transplant Rep (2017) 0.75
Fibrinolysis for patients with intermediate-risk pulmonary embolism. N Engl J Med (2014) 9.33
An angiogenic role for the human peptide antibiotic LL-37/hCAP-18. J Clin Invest (2003) 3.19
Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases. Proc Natl Acad Sci U S A (2011) 2.61
Randomized, controlled trial of ultrasound-assisted catheter-directed thrombolysis for acute intermediate-risk pulmonary embolism. Circulation (2013) 2.08
Thymosin beta4 is an essential paracrine factor of embryonic endothelial progenitor cell-mediated cardioprotection. Circulation (2008) 1.77
Selective pressure-regulated retroinfusion of fibroblast growth factor-2 into the coronary vein enhances regional myocardial blood flow and function in pigs with chronic myocardial ischemia. J Am Coll Cardiol (2003) 1.62
Cardiac AAV9-S100A1 gene therapy rescues post-ischemic heart failure in a preclinical large animal model. Sci Transl Med (2011) 1.54
Three-dimensional printing of models for preoperative planning and simulation of transcatheter valve replacement. Ann Thorac Surg (2012) 1.46
Myocardial transfection of hypoxia inducible factor-1alpha via an adenoviral vector during coronary artery bypass grafting. - A multicenter phase I and safety study -. Circ J (2010) 1.46
Transcutaneous aortic valve replacement with the Edwards SAPIEN XT and Medtronic CoreValve prosthesis under fluoroscopic guidance and local anaesthesia only. Heart (2014) 1.43
In vitro and in vivo proof of tolerance after two-step haploidentical bone marrow and kidney transplantation of the same donor. Transplantation (2012) 1.39
Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis. J Clin Invest (2013) 1.32
Inhibition of microRNA-92a protects against ischemia/reperfusion injury in a large-animal model. Circulation (2013) 1.31
Tracking genes of ecological relevance using a genome scan in two independent regional population samples of Arabis alpina. Mol Ecol (2010) 1.31
Germline transgenic pigs by Sleeping Beauty transposition in porcine zygotes and targeted integration in the pig genome. PLoS One (2011) 1.23
Cross-species hybridisation of human and bovine orthologous genes on high density cDNA microarrays. BMC Genomics (2004) 1.16
Telomere length is reset during early mammalian embryogenesis. Proc Natl Acad Sci U S A (2004) 1.14
RAGE and ICAM-1 cooperate in mediating leukocyte recruitment during acute inflammation in vivo. Blood (2010) 1.14
Cellular and molecular deviations in bovine in vitro-produced embryos are related to the large offspring syndrome. Biol Reprod (2002) 1.09
A ubiquitous chromatin opening element prevents transgene silencing in pluripotent stem cells and their differentiated progeny. Stem Cells (2013) 1.09
Cotransfection of vascular endothelial growth factor-A and platelet-derived growth factor-B via recombinant adeno-associated virus resolves chronic ischemic malperfusion role of vessel maturation. J Am Coll Cardiol (2010) 1.09
The contribution of farm animals to human health. Trends Biotechnol (2004) 1.08
Cytoplasmic injection of circular plasmids allows targeted expression in mammalian embryos. Biotechniques (2009) 1.07
Transcatheter Edwards Sapien XT valve in valve implantation in degenerated aortic bioprostheses via transfemoral access. Clin Res Cardiol (2012) 1.06
Reduction of pacemaker implantation rates after CoreValve® implantation by moderate predilatation. EuroIntervention (2014) 1.05
Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation. Arterioscler Thromb Vasc Biol (2004) 1.05
Knockdown of porcine endogenous retrovirus (PERV) expression by PERV-specific shRNA in transgenic pigs. Xenotransplantation (2008) 1.04
Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veins: comparison with surgical and percutaneous intramyocardial gene delivery. J Am Coll Cardiol (2004) 1.03
Isolation of murine and porcine fetal stem cells from somatic tissue. Biol Reprod (2004) 1.03
Edwards Sapien XT valve placement as treatment option for aortic regurgitation after transfemoral CoreValve implantation: a multicenter experience. Clin Res Cardiol (2013) 1.03
Pigs transgenic for human thrombomodulin have elevated production of activated protein C. Xenotransplantation (2009) 1.01
HLA-E/human beta2-microglobulin transgenic pigs: protection against xenogeneic human anti-pig natural killer cell cytotoxicity. Transplantation (2009) 1.00
Retroinfusion of embryonic endothelial progenitor cells attenuates ischemia-reperfusion injury in pigs: role of phosphatidylinositol 3-kinase/AKT kinase. Circulation (2005) 1.00
Conserved molecular portraits of bovine and human blastocysts as a consequence of the transition from maternal to embryonic control of gene expression. Physiol Genomics (2007) 0.99
Limiting dilution bisulfite (pyro)sequencing reveals parent-specific methylation patterns in single early mouse embryos and bovine oocytes. Epigenetics (2011) 0.99
Epigenetic silencing and tissue independent expression of a novel tetracycline inducible system in double-transgenic pigs. FASEB J (2006) 0.99
Multi-site analytical evaluation of the Abbott ARCHITECT tacrolimus assay. Ther Drug Monit (2009) 0.99
Messenger RNA expression patterns in bovine embryos derived from in vitro procedures and their implications for development. Reprod Fertil Dev (2005) 0.99
Accuracy of dynamic computed tomography adenosine stress myocardial perfusion imaging in estimating myocardial blood flow at various degrees of coronary artery stenosis using a porcine animal model. Invest Radiol (2012) 0.98
Oct4-enhanced green fluorescent protein transgenic pigs: a new large animal model for reprogramming studies. Stem Cells Dev (2011) 0.97
Comparison of real-time polymerase chain reaction and end-point polymerase chain reaction for the analysis of gene expression in preimplantation embryos. Reprod Fertil Dev (2006) 0.97
First inducible transgene expression in porcine large animal models. FASEB J (2011) 0.96
Advances in farm animal transgenesis. Prev Vet Med (2011) 0.96
The human cytomegalovirus UL11 protein interacts with the receptor tyrosine phosphatase CD45, resulting in functional paralysis of T cells. PLoS Pathog (2011) 0.96
Development and validation of a highly efficient protocol of porcine somatic cloning using preovulatory embryo transfer in peripubertal gilts. Cloning Stem Cells (2008) 0.95
Mitochondrial thioredoxin reductase is essential for early postischemic myocardial protection. Circulation (2011) 0.95
DNA methylation in porcine preimplantation embryos developed in vivo and produced by in vitro fertilization, parthenogenetic activation and somatic cell nuclear transfer. Epigenetics (2011) 0.95
Effect of CD34 cell dose on hematopoietic reconstitution and outcome in 508 patients with multiple myeloma undergoing autologous peripheral blood stem cell transplantation. Eur J Haematol (2006) 0.94
Gene therapy for ischemic heart disease. Expert Opin Biol Ther (2011) 0.94
DNA methylation patterns reflect epigenetic reprogramming in bovine embryos. Cell Reprogram (2010) 0.93
The bovine IGF2 gene is differentially methylated in oocyte and sperm DNA. Genomics (2006) 0.93
DNA methylation in the IGF2 intragenic DMR is re-established in a sex-specific manner in bovine blastocysts after somatic cloning. Genomics (2009) 0.92