Published in Vaccine on December 29, 2009
Antibody-profiling technologies for studying humoral responses to infectious agents. Expert Rev Vaccines (2010) 1.67
Vaccination against Chlamydia genital infection utilizing the murine C. muridarum model. Infect Immun (2010) 1.33
Approach to discover T- and B-cell antigens of intracellular pathogens applied to the design of Chlamydia trachomatis vaccines. Proc Natl Acad Sci U S A (2011) 1.27
Plasmodium immunomics. Int J Parasitol (2010) 1.09
Schistosomiasis vaccine discovery using immunomics. Parasit Vectors (2010) 1.03
Identification of the feline humoral immune response to Bartonella henselae infection by protein microarray. PLoS One (2010) 1.03
Protein microarray analysis of antibody responses to Plasmodium falciparum in western Kenyan highland sites with differing transmission levels. PLoS One (2013) 1.00
Leptospiral outer membrane protein microarray, a novel approach to identification of host ligand-binding proteins. J Bacteriol (2012) 0.94
Identification of immunodominant antigens by probing a whole Chlamydia trachomatis open reading frame proteome microarray using sera from immunized mice. Infect Immun (2010) 0.90
Measurement of antibody responses to Modified Vaccinia virus Ankara (MVA) and Dryvax(®) using proteome microarrays and development of recombinant protein ELISAs. Vaccine (2011) 0.84
Proteomic identification of immunodominant chlamydial antigens in a mouse model. J Proteomics (2012) 0.84
Immunity and vaccines against sexually transmitted Chlamydia trachomatis infection. Curr Opin Infect Dis (2011) 0.83
Predicting antigenicity of proteins in a bacterial proteome; a protein microarray and naïve Bayes classification approach. Chem Biodivers (2012) 0.82
Vaccination with a UV-irradiated genetically attenuated mutant of Staphylococcus aureus provides protection against subsequent systemic infection. J Infect Dis (2012) 0.81
Whole genome identification of C. trachomatis immunodominant antigens after genital tract infections and effect of antibiotic treatment of pigtailed macaques. J Proteomics (2014) 0.81
Resolution of Chlamydia trachomatis Infection Is Associated with a Distinct T Cell Response Profile. Clin Vaccine Immunol (2015) 0.80
Large screen approaches to identify novel malaria vaccine candidates. Vaccine (2015) 0.80
A systems biology approach for diagnostic and vaccine antigen discovery in tropical infectious diseases. Curr Opin Infect Dis (2015) 0.78
Assessment of the role in protection and pathogenesis of the Chlamydia muridarum V-type ATP synthase subunit A (AtpA) (TC0582). Microbes Infect (2013) 0.76
Update on Chlamydia trachomatis Vaccinology. Clin Vaccine Immunol (2017) 0.75
TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol (1989) 31.72
Variance stabilization applied to microarray data calibration and to the quantification of differential expression. Bioinformatics (2002) 20.59
Purification and partial characterization of the major outer membrane protein of Chlamydia trachomatis. Infect Immun (1981) 18.13
A Bayesian framework for the analysis of microarray expression data: regularized t -test and statistical inferences of gene changes. Bioinformatics (2001) 16.47
Quadrivalent vaccine against human papillomavirus to prevent high-grade cervical lesions. N Engl J Med (2007) 15.40
Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis. Science (1998) 13.64
New knowledge of chlamydiae and the diseases they cause. J Infect Dis (1975) 9.35
Hepatitis B vaccine: demonstration of efficacy in a controlled clinical trial in a high-risk population in the United States. N Engl J Med (1980) 9.34
The rôle of Chlamydia trachomatis in genital-tract and associated diseases. J Clin Pathol (1980) 6.42
Diversity of Chlamydia trachomatis major outer membrane protein genes. J Bacteriol (1987) 6.16
Prevalence of chlamydial and gonococcal infections among young adults in the United States. JAMA (2004) 5.66
Pelvic inflammatory disease and fertility. A cohort study of 1,844 women with laparoscopically verified disease and 657 control women with normal laparoscopic results. Sex Transm Dis (1992) 5.19
Antigenic analysis of the major outer membrane protein of Chlamydia spp. Infect Immun (1982) 4.82
Immunity to murine chlamydial genital infection. Infect Immun (2002) 4.64
Immunology of Chlamydia infection: implications for a Chlamydia trachomatis vaccine. Nat Rev Immunol (2005) 4.50
AN UNIDENTIFIED VIRUS WHICH PRODUCES PNEUMONIA AND SYSTEMIC INFECTION IN MICE. Science (1942) 4.30
Systemic immunization with papillomavirus L1 protein completely prevents the development of viral mucosal papillomas. Proc Natl Acad Sci U S A (1995) 4.15
Multiple comparison procedures updated. Clin Exp Pharmacol Physiol (1998) 3.92
Profiling the humoral immune response to infection by using proteome microarrays: high-throughput vaccine and diagnostic antigen discovery. Proc Natl Acad Sci U S A (2005) 3.59
Intravaginal inoculation of mice with the Chlamydia trachomatis mouse pneumonitis biovar results in infertility. Infect Immun (1994) 2.73
Profiling humoral immune responses to P. falciparum infection with protein microarrays. Proteomics (2008) 2.43
Biosynthesis and disulfide cross-linking of outer membrane components during the growth cycle of Chlamydia trachomatis. Infect Immun (1987) 2.26
A genome-wide proteome array reveals a limited set of immunogens in natural infections of humans and white-footed mice with Borrelia burgdorferi. Infect Immun (2008) 2.15
Vaccination with the Chlamydia trachomatis major outer membrane protein can elicit an immune response as protective as that resulting from inoculation with live bacteria. Infect Immun (2005) 2.13
Proteome-wide analysis of the serological response to vaccinia and smallpox. Proteomics (2007) 2.10
Chlamydia trachomatis-induced salpingitis in mice. J Infect Dis (1983) 1.99
Immunodominant Francisella tularensis antigens identified using proteome microarray. Proteomics (2007) 1.85
The potential for vaccine against infection of the genital tract with Chlamydia trachomatis. Sex Transm Dis (1999) 1.84
Mechanisms for mucosal immunogenicity and adjuvancy of Escherichia coli labile enterotoxin. J Infect Dis (1996) 1.68
From protein microarrays to diagnostic antigen discovery: a study of the pathogen Francisella tularensis. Bioinformatics (2007) 1.68
Profiling of human antibody responses to Chlamydia trachomatis urogenital tract infection using microplates arrayed with 156 chlamydial fusion proteins. Infect Immun (2006) 1.67
CD8+ T cells recognize an inclusion membrane-associated protein from the vacuolar pathogen Chlamydia trachomatis. Proc Natl Acad Sci U S A (2001) 1.64
Molecular cloning and sequence analysis of a developmentally regulated cysteine-rich outer membrane protein from Chlamydia trachomatis. Gene (1988) 1.56
Protection against infertility in a BALB/c mouse salpingitis model by intranasal immunization with the mouse pneumonitis biovar of Chlamydia trachomatis. Infect Immun (1994) 1.54
Vaccine adjuvants: current challenges and future approaches. J Pharm Sci (2009) 1.50
A new computer model for estimating the impact of vaccination protocols and its application to the study of Chlamydia trachomatis genital infections. Vaccine (1995) 1.35
Chlamydia trachomatis contains a protein similar to the Legionella pneumophila mip gene product. Mol Microbiol (1991) 1.35
Cysteine-rich outer membrane proteins of Chlamydia trachomatis display compensatory sequence changes between biovariants. Mol Microbiol (1990) 1.31
Proteomic profiling and identification of immunodominant spore antigens of Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis. Appl Environ Microbiol (2006) 1.29
Identification of immunodominant antigens from Helicobacter pylori and evaluation of their reactivities with sera from patients with different gastroduodenal pathologies. Infect Immun (2000) 1.23
Structural and functional analyses of the major outer membrane protein of Chlamydia trachomatis. J Bacteriol (2007) 1.21
Chlamydial serology: comparative diagnostic value of immunoblotting, microimmunofluorescence test, and immunoassays using different recombinant proteins as antigens. J Clin Microbiol (2001) 1.19
Mouse strain-dependent chemokine regulation of the genital tract T helper cell type 1 immune response. Infect Immun (2001) 1.11
Prediction of the membrane-spanning beta-strands of the major outer membrane protein of Chlamydia. Protein Sci (2002) 1.10
Vaccine adjuvants: scientific challenges and strategic initiatives. Expert Rev Vaccines (2009) 1.07
An indirect asymmetrical sandwich ELISA using anti-allotype antibodies for the specific and quantitative measurement of mouse IgG2a of Igh-1b allotype. J Immunol Methods (1989) 1.06
Characterization of the disulfide bonds and free cysteine residues of the Chlamydia trachomatis mouse pneumonitis major outer membrane protein. Biochemistry (2005) 1.05
Epitopes associated with a synthetic hepatitis B surface antigen peptide. J Immunol (1983) 1.02
Sequence of the gene encoding the major outer membrane protein of the mouse pneumonitis biovar of Chlamydia trachomatis. Gene (1991) 1.00
New murine model for the study of Chlamydia trachomatis genitourinary tract infections in males. Infect Immun (2004) 0.98
Sequence diversity of the 60-kilodalton protein and of a putative 15-kilodalton protein between the trachoma and lymphogranuloma venereum biovars of Chlamydia trachomatis. Infect Immun (1991) 0.94
Previously undetected Chlamydia trachomatis infection, immunity to heat shock proteins and tubal occlusion in women undergoing in-vitro fertilization. Hum Reprod (1999) 0.93
OspA lipoprotein of Borrelia burgdorferi is a mucosal immunogen and adjuvant. Vaccine (1997) 0.89
Mouse model of respiratory Chlamydia pneumoniae infection for a genomic screen of subunit vaccine candidates. Vaccine (2006) 0.85
Immunogenic and protective ability of the two developmental forms of Chlamydiae in a mouse model of infertility. Vaccine (1999) 0.84
Identification of an iron-responsive protein that is antigenic in patients with Chlamydia trachomatis genital infections. FEMS Immunol Med Microbiol (2007) 0.83
Induction of protective immunity against a Chlamydia trachomatis genital infection in three genetically distinct strains of mice. Immunology (2003) 0.82
Improving the prediction of protein secondary structure in three and eight classes using recurrent neural networks and profiles. Proteins (2002) 5.29
An enhanced MITOMAP with a global mtDNA mutational phylogeny. Nucleic Acids Res (2006) 4.51
Global landscape of recent inferred Darwinian selection for Homo sapiens. Proc Natl Acad Sci U S A (2005) 3.77
A tandem affinity tag for two-step purification under fully denaturing conditions: application in ubiquitin profiling and protein complex identification combined with in vivocross-linking. Mol Cell Proteomics (2006) 3.62
Profiling the humoral immune response to infection by using proteome microarrays: high-throughput vaccine and diagnostic antigen discovery. Proc Natl Acad Sci U S A (2005) 3.59
MITOMAP: a human mitochondrial genome database--2004 update. Nucleic Acids Res (2005) 3.35
Prediction of protein stability changes for single-site mutations using support vector machines. Proteins (2006) 3.00
A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray. Proc Natl Acad Sci U S A (2010) 2.90
Prediction of coordination number and relative solvent accessibility in proteins. Proteins (2002) 2.66
Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities. Immunity (2008) 2.43
Profiling humoral immune responses to P. falciparum infection with protein microarrays. Proteomics (2008) 2.43
Global gene expression profiling in Escherichia coli K12. The effects of oxygen availability and FNR. J Biol Chem (2003) 2.32
Imaging of effector memory T cells during a delayed-type hypersensitivity reaction and suppression by Kv1.3 channel block. Immunity (2008) 2.23
Coordination of the transcriptome and metabolome by the circadian clock. Proc Natl Acad Sci U S A (2012) 2.22
Vaccinia virus H3L envelope protein is a major target of neutralizing antibodies in humans and elicits protection against lethal challenge in mice. J Virol (2005) 2.18
ChemDB: a public database of small molecules and related chemoinformatics resources. Bioinformatics (2005) 2.16
A genome-wide proteome array reveals a limited set of immunogens in natural infections of humans and white-footed mice with Borrelia burgdorferi. Infect Immun (2008) 2.15
Vaccination with the Chlamydia trachomatis major outer membrane protein can elicit an immune response as protective as that resulting from inoculation with live bacteria. Infect Immun (2005) 2.13
Dynamic antibody responses to the Mycobacterium tuberculosis proteome. Proc Natl Acad Sci U S A (2010) 2.12
Proteome-wide analysis of the serological response to vaccinia and smallpox. Proteomics (2007) 2.10
A Burkholderia pseudomallei protein microarray reveals serodiagnostic and cross-reactive antigens. Proc Natl Acad Sci U S A (2009) 2.10
Improved residue contact prediction using support vector machines and a large feature set. BMC Bioinformatics (2007) 2.03
Data structures and compression algorithms for genomic sequence data. Bioinformatics (2009) 1.96
Bayesian surprise attracts human attention. Vision Res (2008) 1.86
Graph kernels for chemical informatics. Neural Netw (2005) 1.86
Bounds and algorithms for fast exact searches of chemical fingerprints in linear and sublinear time. J Chem Inf Model (2007) 1.86
Immunodominant Francisella tularensis antigens identified using proteome microarray. Proteomics (2007) 1.85
ChemDB update--full-text search and virtual chemical space. Bioinformatics (2007) 1.83
PEPITO: improved discontinuous B-cell epitope prediction using multiple distance thresholds and half sphere exposure. Bioinformatics (2008) 1.78
Redundancy and plasticity of neutralizing antibody responses are cornerstone attributes of the human immune response to the smallpox vaccine. J Virol (2008) 1.77
Antibody profiling by proteome microarray reveals the immunogenicity of the attenuated smallpox vaccine modified vaccinia virus ankara is comparable to that of Dryvax. J Virol (2007) 1.77
A machine learning information retrieval approach to protein fold recognition. Bioinformatics (2006) 1.75
MotifMap: a human genome-wide map of candidate regulatory motif sites. Bioinformatics (2008) 1.73
Global gene expression profiling in Escherichia coli K12: effects of oxygen availability and ArcA. J Biol Chem (2005) 1.73
Hemoglobin S and C heterozygosity enhances neither the magnitude nor breadth of antibody responses to a diverse array of Plasmodium falciparum antigens. J Infect Dis (2011) 1.71
Global gene expression profiling in Escherichia coli K12. The effects of leucine-responsive regulatory protein. J Biol Chem (2002) 1.69
From protein microarrays to diagnostic antigen discovery: a study of the pathogen Francisella tularensis. Bioinformatics (2007) 1.68
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation. J Cell Biol (2009) 1.65
Identification of humoral immune responses in protein microarrays using DNA microarray data analysis techniques. Bioinformatics (2006) 1.65
Development of a novel cross-linking strategy for fast and accurate identification of cross-linked peptides of protein complexes. Mol Cell Proteomics (2010) 1.61
Cyber-T web server: differential analysis of high-throughput data. Nucleic Acids Res (2012) 1.58
COBEpro: a novel system for predicting continuous B-cell epitopes. Protein Eng Des Sel (2008) 1.54
Sterile protective immunity to malaria is associated with a panel of novel P. falciparum antigens. Mol Cell Proteomics (2011) 1.53
Antigen-specific acquired immunity in human brucellosis: implications for diagnosis, prognosis, and vaccine development. Front Cell Infect Microbiol (2012) 1.52
Kernels for small molecules and the prediction of mutagenicity, toxicity and anti-cancer activity. Bioinformatics (2005) 1.47
Deep architectures for protein contact map prediction. Bioinformatics (2012) 1.44
Differential analysis of DNA microarray gene expression data. Mol Microbiol (2003) 1.43
Ovol1 regulates the growth arrest of embryonic epidermal progenitor cells and represses c-myc transcription. J Cell Biol (2006) 1.42
Structure-based inhibitor design of AccD5, an essential acyl-CoA carboxylase carboxyltransferase domain of Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2006) 1.42
Large-scale prediction of disulphide bridges using kernel methods, two-dimensional recursive neural networks, and weighted graph matching. Proteins (2006) 1.41
Assessment of predictions submitted for the CASP7 domain prediction category. Proteins (2007) 1.39
Retroviruses and yeast retrotransposons use overlapping sets of host genes. Genome Res (2005) 1.38
The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory. Nat Neurosci (2013) 1.36
Chlamydia trachomatis native major outer membrane protein induces partial protection in nonhuman primates: implication for a trachoma transmission-blocking vaccine. J Immunol (2009) 1.33
Leptin engages a hypothalamic neurocircuitry to permit survival in the absence of insulin. Cell Metab (2013) 1.32
Data structures and compression algorithms for high-throughput sequencing technologies. BMC Bioinformatics (2010) 1.31
An extremely diverse CD4 response to vaccinia virus in humans is revealed by proteome-wide T-cell profiling. J Virol (2008) 1.27
Distribution patterns of over-represented k-mers in non-coding yeast DNA. Bioinformatics (2002) 1.25
Identification of a common immune signature in murine and human systemic Salmonellosis. Proc Natl Acad Sci U S A (2012) 1.25
Systems biology approach predicts antibody signature associated with Brucella melitensis infection in humans. J Proteome Res (2011) 1.24
The stability and complexity of antibody responses to the major surface antigen of Plasmodium falciparum are associated with age in a malaria endemic area. Mol Cell Proteomics (2011) 1.24
Why are complementary DNA strands symmetric? Bioinformatics (2002) 1.23
Transcriptionally active polymerase chain reaction (TAP): high throughput gene expression using genome sequence data. J Biol Chem (2001) 1.23
Up-regulation of the JAK/STAT1 signal pathway during Chlamydia trachomatis infection. J Immunol (2005) 1.22
Candidate antigens for Q fever serodiagnosis revealed by immunoscreening of a Coxiella burnetii protein microarray. Clin Vaccine Immunol (2008) 1.22
Structural and functional analyses of the major outer membrane protein of Chlamydia trachomatis. J Bacteriol (2007) 1.21
Immune profiling with a Salmonella Typhi antigen microarray identifies new diagnostic biomarkers of human typhoid. Sci Rep (2013) 1.20
Reversal of the antichlamydial activity of putative type III secretion inhibitors by iron. Infect Immun (2007) 1.20
A CROC stronger than ROC: measuring, visualizing and optimizing early retrieval. Bioinformatics (2010) 1.20
Submicroscopic and asymptomatic Plasmodium falciparum and Plasmodium vivax infections are common in western Thailand - molecular and serological evidence. Malar J (2015) 1.17
Three-stage prediction of protein beta-sheets by neural networks, alignments and graph algorithms. Bioinformatics (2005) 1.16
Developmental phenotypes and reduced Wnt signaling in mice deficient for pygopus 2. Genesis (2007) 1.15
Immunization with the Chlamydia trachomatis mouse pneumonitis major outer membrane protein by use of CpG oligodeoxynucleotides as an adjuvant induces a protective immune response against an intranasal chlamydial challenge. Infect Immun (2002) 1.15
Protection against an intranasal challenge by vaccines formulated with native and recombinant preparations of the Chlamydia trachomatis major outer membrane protein. Vaccine (2009) 1.15
SOLpro: accurate sequence-based prediction of protein solubility. Bioinformatics (2009) 1.14
CircadiOmics: integrating circadian genomics, transcriptomics, proteomics and metabolomics. Nat Methods (2012) 1.14
LineUp: statistical detection of chromosomal homology with application to plant comparative genomics. Genome Res (2003) 1.14
Discovery of power-laws in chemical space. J Chem Inf Model (2008) 1.11
Genome-wide identification of Bcl11b gene targets reveals role in brain-derived neurotrophic factor signaling. PLoS One (2011) 1.11