Published in Annu Rev Pharmacol Toxicol on January 01, 2010
Toxicity of Ag, CuO and ZnO nanoparticles to selected environmentally relevant test organisms and mammalian cells in vitro: a critical review. Arch Toxicol (2013) 2.12
Mechanisms of carbon nanotube-induced toxicity: focus on oxidative stress. Toxicol Appl Pharmacol (2012) 1.45
Impaired clearance and enhanced pulmonary inflammatory/fibrotic response to carbon nanotubes in myeloperoxidase-deficient mice. PLoS One (2012) 1.32
Coating carbon nanotubes with a polystyrene-based polymer protects against pulmonary toxicity. Part Fibre Toxicol (2011) 1.25
Genotoxicity of carbon nanofibers: are they potentially more or less dangerous than carbon nanotubes or asbestos? Toxicol Appl Pharmacol (2011) 1.25
Interactions of nanomaterials and biological systems: Implications to personalized nanomedicine. Adv Drug Deliv Rev (2012) 1.18
Delivery of chemotherapeutic drugs in tumour cell-derived microparticles. Nat Commun (2012) 1.18
Effects of copper nanoparticle exposure on host defense in a murine pulmonary infection model. Part Fibre Toxicol (2011) 1.03
Gene expression profiling of immune-competent human cells exposed to engineered zinc oxide or titanium dioxide nanoparticles. PLoS One (2013) 1.02
Microsomal glutathione transferase 1 protects against toxicity induced by silica nanoparticles but not by zinc oxide nanoparticles. ACS Nano (2012) 0.98
Revisiting 30 years of biofunctionalization and surface chemistry of inorganic nanoparticles for nanomedicine. Front Chem (2014) 0.97
Cell delivery of therapeutic nanoparticles. Prog Mol Biol Transl Sci (2011) 0.97
Global phospholipidomics analysis reveals selective pulmonary peroxidation profiles upon inhalation of single-walled carbon nanotubes. ACS Nano (2011) 0.97
Carbon nanotube-based multi electrode arrays for neuronal interfacing: progress and prospects. Front Neural Circuits (2013) 0.96
Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness. Nat Nanotechnol (2011) 0.94
Bions: a family of biomimetic mineralo-organic complexes derived from biological fluids. PLoS One (2013) 0.91
Effects of serum on cytotoxicity of nano- and micro-sized ZnO particles. J Nanopart Res (2013) 0.88
Production of indole-3-acetic acid via the indole-3-acetamide pathway in the plant-beneficial bacterium Pseudomonas chlororaphis O6 is inhibited by ZnO nanoparticles but enhanced by CuO nanoparticles. Appl Environ Microbiol (2011) 0.88
Protein bio-corona: critical issue in immune nanotoxicology. Arch Toxicol (2016) 0.87
Effects of PVA coated nanoparticles on human immune cells. Int J Nanomedicine (2015) 0.85
High resolution characterization of engineered nanomaterial dispersions in complex media using tunable resistive pulse sensing technology. ACS Nano (2014) 0.85
Experimental tools to study molecular recognition within the nanoparticle corona. Sensors (Basel) (2014) 0.85
NanoMiner - integrative human transcriptomics data resource for nanoparticle research. PLoS One (2013) 0.82
Nanomaterials toxicity and cell death modalities. J Drug Deliv (2012) 0.82
Nanotoxicology ten years later: Lights and shadows. Toxicol Appl Pharmacol (2016) 0.81
Graphene oxide attenuates Th2-type immune responses, but augments airway remodeling and hyperresponsiveness in a murine model of asthma. ACS Nano (2014) 0.80
Zinc Oxide Nanoparticles Affect Biomass Accumulation and Photosynthesis in Arabidopsis. Front Plant Sci (2016) 0.79
Probabilistic modelling of prospective environmental concentrations of gold nanoparticles from medical applications as a basis for risk assessment. J Nanobiotechnology (2015) 0.79
Chip based single cell analysis for nanotoxicity assessment. Analyst (2014) 0.79
Intracellular signal modulation by nanomaterials. Adv Exp Med Biol (2014) 0.78
Size-Dependent Toxicity of Gold Nanoparticles on Human Embryonic Stem Cells and Their Neural Derivatives. Small (2015) 0.78
New clathrin-based nanoplatforms for magnetic resonance imaging. PLoS One (2012) 0.78
The Ginkgo biloba Extract Reverses the Renal Effects of Titanium Dioxide Nanoparticles in Adult Male Rats. Biochem Res Int (2016) 0.76
Recent Advances in Nanoparticle-Mediated Delivery of Anti-Inflammatory Phytocompounds. Int J Mol Sci (2017) 0.75
Quantitative analysis of nanoparticle transport through in vitro blood-brain barrier models. Tissue Barriers (2016) 0.75
Interactions between Al₁₂X (X = Al, C, N and P) nanoparticles and DNA nucleobases/base pairs: implications for nanotoxicity. J Mol Model (2011) 0.75
Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice. Am J Physiol Lung Cell Mol Physiol (2005) 7.28
HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease). Nat Genet (2006) 3.03
Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation. Nat Nanotechnol (2010) 2.26
Lipid accumulation and dendritic cell dysfunction in cancer. Nat Med (2010) 2.21
Late-onset neutropenia following rituximab therapy in rheumatic diseases: association with B lymphocyte depletion and infections. Arthritis Rheum (2011) 2.06
Targeting mitochondria. Acc Chem Res (2008) 2.03
Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release. Part Fibre Toxicol (2014) 1.77
Therapeutic hypothermia preserves antioxidant defenses after severe traumatic brain injury in infants and children. Crit Care Med (2009) 1.70
S-nitrosoalbumin-mediated relaxation is enhanced by ascorbate and copper: effects in pregnancy and preeclampsia plasma. Hypertension (2004) 1.69
Peroxidase activity and structural transitions of cytochrome c bound to cardiolipin-containing membranes. Biochemistry (2006) 1.62
Biodegradation of single-walled carbon nanotubes through enzymatic catalysis. Nano Lett (2008) 1.60
Sequential exposure to carbon nanotubes and bacteria enhances pulmonary inflammation and infectivity. Am J Respir Cell Mol Biol (2007) 1.60
Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury. Nat Neurosci (2012) 1.58
A role for oxidative stress in apoptosis: oxidation and externalization of phosphatidylserine is required for macrophage clearance of cells undergoing Fas-mediated apoptosis. J Immunol (2002) 1.56
Mitochondrial targeting of selective electron scavengers: synthesis and biological analysis of hemigramicidin-TEMPO conjugates. J Am Chem Soc (2005) 1.50
Starving neurons show sex difference in autophagy. J Biol Chem (2008) 1.49
Toxicology of engineered nanomaterials: focus on biocompatibility, biodistribution and biodegradation. Biochim Biophys Acta (2010) 1.48
Thioredoxin and lipoic acid catalyze the denitrosation of low molecular weight and protein S-nitrosothiols. J Am Chem Soc (2005) 1.45
Mechanisms of carbon nanotube-induced toxicity: focus on oxidative stress. Toxicol Appl Pharmacol (2012) 1.45
Aberrant mitochondrial iron distribution and maturation arrest characterize early erythroid precursors in low-risk myelodysplastic syndromes. Blood (2005) 1.44
Assessment of antioxidant reserves and oxidative stress in cerebrospinal fluid after severe traumatic brain injury in infants and children. Pediatr Res (2002) 1.42
Ablation of the pro-apoptotic protein Bax protects mice from glucocorticoid-induced bone growth impairment. PLoS One (2012) 1.41
The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: From respiration to apoptosis. Mitochondrion (2011) 1.40
A mitochondria-targeted nitroxide/hemigramicidin S conjugate protects mouse embryonic cells against gamma irradiation. Int J Radiat Oncol Biol Phys (2008) 1.39
Single-walled carbon nanotubes: geno- and cytotoxic effects in lung fibroblast V79 cells. J Toxicol Environ Health A (2007) 1.37
Macrophage clearance of neutrophil extracellular traps is a silent process. J Immunol (2013) 1.37
Cardiolipin switch in mitochondria: shutting off the reduction of cytochrome c and turning on the peroxidase activity. Biochemistry (2007) 1.36
Structural requirements for optimized delivery, inhibition of oxidative stress, and antiapoptotic activity of targeted nitroxides. J Pharmacol Exp Ther (2006) 1.36
Mechanistic investigations of horseradish peroxidase-catalyzed degradation of single-walled carbon nanotubes. J Am Chem Soc (2009) 1.34
Macrophage recognition of externalized phosphatidylserine and phagocytosis of apoptotic Jurkat cells--existence of a threshold. Arch Biochem Biophys (2003) 1.33
Impaired clearance and enhanced pulmonary inflammatory/fibrotic response to carbon nanotubes in myeloperoxidase-deficient mice. PLoS One (2012) 1.32
Two strategies for the development of mitochondrion-targeted small molecule radiation damage mitigators. Int J Radiat Oncol Biol Phys (2011) 1.29
Selective early cardiolipin peroxidation after traumatic brain injury: an oxidative lipidomics analysis. Ann Neurol (2007) 1.29
Vascular endothelial growth factor prolongs survival in a transgenic mouse model of ALS. Ann Neurol (2004) 1.26
A mitochondria-targeted triphenylphosphonium-conjugated nitroxide functions as a radioprotector/mitigator. Radiat Res (2009) 1.26
Enhanced oxidative stress in iNOS-deficient mice after traumatic brain injury: support for a neuroprotective role of iNOS. J Cereb Blood Flow Metab (2005) 1.23
Oxidative stress in immature brain after traumatic brain injury. Dev Neurosci (2006) 1.22
Bench-to-bedside review: Mitochondrial injury, oxidative stress and apoptosis--there is nothing more practical than a good theory. Crit Care (2008) 1.22
Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos. Part Fibre Toxicol (2012) 1.21
The enzymatic oxidation of graphene oxide. ACS Nano (2011) 1.21
Oxidative lipidomics of hyperoxic acute lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation. Am J Physiol Lung Cell Mol Physiol (2010) 1.19
Neuronal NOS-mediated nitration and inactivation of manganese superoxide dismutase in brain after experimental and human brain injury. J Neurochem (2007) 1.19
Oxidative lipidomics of gamma-irradiation-induced intestinal injury. Free Radic Biol Med (2007) 1.18
Nitric oxide inhibits peroxidase activity of cytochrome c.cardiolipin complex and blocks cardiolipin oxidation. J Biol Chem (2006) 1.18
Orphan nuclear receptor pregnane X receptor sensitizes oxidative stress responses in transgenic mice and cancerous cells. Mol Endocrinol (2005) 1.17
Phosphatidylserine targets single-walled carbon nanotubes to professional phagocytes in vitro and in vivo. PLoS One (2009) 1.16
Involvement of a functional NADPH oxidase in neutrophils and macrophages during programmed cell clearance: implications for chronic granulomatous disease. Am J Physiol Cell Physiol (2009) 1.16
Efficient internalization of silica-coated iron oxide nanoparticles of different sizes by primary human macrophages and dendritic cells. Toxicol Appl Pharmacol (2011) 1.16
The mitochondria-targeted nitroxide JP4-039 augments potentially lethal irradiation damage repair. In Vivo (2009) 1.14
Mass-spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury. J Neurochem (2010) 1.14
Mass-spectrometric characterization of phospholipids and their primary peroxidation products in rat cortical neurons during staurosporine-induced apoptosis. J Neurochem (2008) 1.13
Ascorbate as a "redox sensor" and protector against irradiation-induced oxidative stress in 32D CL 3 hematopoietic cells and subclones overexpressing human manganese superoxide dismutase. Int J Radiat Oncol Biol Phys (2004) 1.13
Hemigramicidin-TEMPO conjugates: novel mitochondria-targeted anti-oxidants. Biochem Pharmacol (2007) 1.13
NADPH oxidase-dependent oxidation and externalization of phosphatidylserine during apoptosis in Me2SO-differentiated HL-60 cells. Role in phagocytic clearance. J Biol Chem (2002) 1.12
Lipid antioxidant, etoposide, inhibits phosphatidylserine externalization and macrophage clearance of apoptotic cells by preventing phosphatidylserine oxidation. J Biol Chem (2003) 1.12
Vitamin E deficiency enhances pulmonary inflammatory response and oxidative stress induced by single-walled carbon nanotubes in C57BL/6 mice. Toxicol Appl Pharmacol (2007) 1.11
The hierarchy of structural transitions induced in cytochrome c by anionic phospholipids determines its peroxidase activation and selective peroxidation during apoptosis in cells. Biochemistry (2007) 1.11
Direct effects of carbon nanotubes on dendritic cells induce immune suppression upon pulmonary exposure. ACS Nano (2011) 1.11
A mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation-induced death. Nat Commun (2011) 1.09
Peroxidase activity of hemoglobin-haptoglobin complexes: covalent aggregation and oxidative stress in plasma and macrophages. J Biol Chem (2009) 1.08
A natural vanishing act: the enzyme-catalyzed degradation of carbon nanomaterials. Acc Chem Res (2012) 1.08
Peroxidase-mediated biodegradation of carbon nanotubes in vitro and in vivo. Adv Drug Deliv Rev (2013) 1.07
The intracellular domain of p75NTR as a determinant of cellular reducing potential and response to oxidant stress. Aging Cell (2005) 1.07
Safety assessment of nanomaterials: implications for nanomedicine. J Control Release (2012) 1.07
Classification framework for graphene-based materials. Angew Chem Int Ed Engl (2014) 1.06
Treatment with a novel hemigramicidin-TEMPO conjugate prolongs survival in a rat model of lethal hemorrhagic shock. Ann Surg (2007) 1.06
Oxidative lipidomics of programmed cell death. Methods Enzymol (2008) 1.05
Nitrosative stress inhibits the aminophospholipid translocase resulting in phosphatidylserine externalization and macrophage engulfment: implications for the resolution of inflammation. J Biol Chem (2007) 1.04
Adsorption of surfactant lipids by single-walled carbon nanotubes in mouse lung upon pharyngeal aspiration. ACS Nano (2012) 1.04
Interplay between bax, reactive oxygen species production, and cardiolipin oxidation during apoptosis. Biochem Biophys Res Commun (2008) 1.03
Oxidation of phosphatidylserine: a mechanism for plasma membrane phospholipid scrambling during apoptosis? Biochem Biophys Res Commun (2004) 1.03
Oxidative lipidomics of γ-radiation-induced lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation. Radiat Res (2011) 1.02
Applying quantitative structure-activity relationship approaches to nanotoxicology: current status and future potential. Toxicology (2012) 1.02
Gene expression profiling of immune-competent human cells exposed to engineered zinc oxide or titanium dioxide nanoparticles. PLoS One (2013) 1.02
Long-term effects of carbon containing engineered nanomaterials and asbestos in the lung: one year postexposure comparisons. Am J Physiol Lung Cell Mol Physiol (2013) 1.01
Clinical presentation of Griscelli syndrome type 2 and spectrum of RAB27A mutations. Pediatr Blood Cancer (2010) 1.01
Biodegradation of single-walled carbon nanotubes by eosinophil peroxidase. Small (2013) 1.01
Programmed cell death: molecular mechanisms and implications for safety assessment of nanomaterials. Acc Chem Res (2012) 1.01
Disruption of the M80-Fe ligation stimulates the translocation of cytochrome c to the cytoplasm and nucleus in nonapoptotic cells. Proc Natl Acad Sci U S A (2009) 1.00
Mechanisms of cardiolipin oxidation by cytochrome c: relevance to pro- and antiapoptotic functions of etoposide. Mol Pharmacol (2006) 1.00
Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli. J Chromatogr B Analyt Technol Biomed Life Sci (2009) 1.00
Phosphatidylserine peroxidation/externalization during staurosporine-induced apoptosis in HL-60 cells. FEBS Lett (2002) 1.00
Oxidative lipidomics of apoptosis: quantitative assessment of phospholipid hydroperoxides in cells and tissues. Methods Mol Biol (2010) 1.00
Screening of biochemical and molecular mechanisms of secondary injury and repair in the brain after experimental blast-induced traumatic brain injury in rats. J Neurotrauma (2013) 0.99
Cardiolipin deficiency leads to decreased cardiolipin peroxidation and increased resistance of cells to apoptosis. Free Radic Biol Med (2008) 0.99
Microsomal glutathione transferase 1 protects against toxicity induced by silica nanoparticles but not by zinc oxide nanoparticles. ACS Nano (2012) 0.98
Induction of caspase- and reactive oxygen species-independent phosphatidylserine externalization in primary human neutrophils: role in macrophage recognition and engulfment. J Leukoc Biol (2008) 0.98