Published in Vet Immunol Immunopathol on December 11, 2009
Neuroprotective roles of the P2Y(2) receptor. Purinergic Signal (2012) 0.84
Adenosine and adenosine receptors in the pathogenesis and treatment of rheumatic diseases. Nat Rev Rheumatol (2016) 0.83
Danger signal adenosine via adenosine 2a receptor stimulates growth of Porphyromonas gingivalis in primary gingival epithelial cells. Mol Oral Microbiol (2014) 0.82
The A2A adenosine receptor is a dual coding gene: a novel mechanism of gene usage and signal transduction. J Biol Chem (2013) 0.76
Activation of A2aR attenuates bleomycin-induced pulmonary fibrosis via the SDF-1/CXCR4 axis-related pathway. Am J Transl Res (2017) 0.75
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med (2007) 10.00
Adenosine receptors: therapeutic aspects for inflammatory and immune diseases. Nat Rev Drug Discov (2008) 4.76
International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors--an update. Pharmacol Rev (2011) 4.16
Immunopathology of schistosomiasis. Immunol Cell Biol (2006) 2.74
A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells. Blood (2007) 2.69
Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation. J Exp Med (2006) 2.62
Cutting edge: Critical role for A2A adenosine receptors in the T cell-mediated regulation of colitis. J Immunol (2006) 2.37
A2A adenosine receptor induction inhibits IFN-gamma production in murine CD4+ T cells. J Immunol (2005) 2.37
Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury. Kidney Int (2009) 2.30
Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: role of macrophages. Am J Physiol Renal Physiol (2004) 2.27
Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: the role of CD4+ T cells and IFN-gamma. J Immunol (2006) 2.22
Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow-derived cells. J Clin Invest (2003) 2.22
APP processing in Alzheimer's disease. Mol Brain (2011) 2.02
Dendritic cells tolerized with adenosine A₂AR agonist attenuate acute kidney injury. J Clin Invest (2012) 2.00
2-Aminothiophene-3-carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers. Bioorg Med Chem (2005) 1.94
Myocardial infarct-sparing effect of adenosine A2A receptor activation is due to its action on CD4+ T lymphocytes. Circulation (2006) 1.94
Infarct-sparing effect of A2A-adenosine receptor activation is due primarily to its action on lymphocytes. Circulation (2005) 1.75
Ginger (Zingiber officinale) reduces muscle pain caused by eccentric exercise. J Pain (2010) 1.71
NKT cells mediate pulmonary inflammation and dysfunction in murine sickle cell disease through production of IFN-gamma and CXCR3 chemokines. Blood (2009) 1.69
Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease. Gastroenterology (2005) 1.66
Therapeutic anti-inflammatory effects of myeloid cell adenosine receptor A2a stimulation in lipopolysaccharide-induced lung injury. J Immunol (2007) 1.62
Lipopolysaccharide rapidly modifies adenosine receptor transcripts in murine and human macrophages: role of NF-kappaB in A(2A) adenosine receptor induction. Biochem J (2005) 1.60
Mycobacterium tuberculosis triggers host type I IFN signaling to regulate IL-1β production in human macrophages. J Immunol (2011) 1.58
Extracellular adenosine regulates naive T cell development and peripheral maintenance. J Exp Med (2013) 1.57
Adenosine A2A receptors induced on iNKT and NK cells reduce pulmonary inflammation and injury in mice with sickle cell disease. Blood (2010) 1.56
Protection from ischemic liver injury by activation of A2A adenosine receptors during reperfusion: inhibition of chemokine induction. Am J Physiol Gastrointest Liver Physiol (2004) 1.55
The origin of the synergistic effect of muramyl dipeptide with endotoxin and peptidoglycan. J Biol Chem (2002) 1.53
Adenosine A2A receptor activation attenuates inflammation and injury in diabetic nephropathy. Am J Physiol Renal Physiol (2005) 1.52
NF-κB is activated in CD4+ iNKT cells by sickle cell disease and mediates rapid induction of adenosine A2A receptors. PLoS One (2013) 1.50
A2B adenosine receptor gene deletion attenuates murine colitis. Gastroenterology (2008) 1.49
Comparison of systemic and retrograde delivery of adenosine A2A agonist for attenuation of spinal cord injury after thoracic aortic cross-clamping. Ann Thorac Surg (2006) 1.44
Additive protection against lung ischemia-reperfusion injury by adenosine A2A receptor activation before procurement and during reperfusion. J Thorac Cardiovasc Surg (2007) 1.42
The A2B adenosine receptor impairs the maturation and immunogenicity of dendritic cells. J Immunol (2009) 1.39
Human A(2A) adenosine receptors: high-affinity agonist binding to receptor-G protein complexes containing Gbeta(4). Mol Pharmacol (2002) 1.39
A novel neutrophil-specific PET imaging agent: cFLFLFK-PEG-64Cu. J Nucl Med (2009) 1.36
Activation of adenosine 2A receptors attenuates allograft rejection and alloantigen recognition. J Immunol (2007) 1.32
A2A adenosine receptor activation improves survival in mouse models of endotoxemia and sepsis. J Infect Dis (2004) 1.32
Adenosine A2A agonists in development for the treatment of inflammation. Expert Opin Investig Drugs (2005) 1.31
Anatomy of adenosine A2A receptors in brain: morphological substrates for integration of striatal function. Neurology (2003) 1.31
A2A adenosine receptors on bone marrow-derived cells protect liver from ischemia-reperfusion injury. J Immunol (2005) 1.30
Adenosine A2B receptor blockade slows growth of bladder and breast tumors. J Immunol (2011) 1.28
CD4+ T lymphocytes mediate acute pulmonary ischemia-reperfusion injury. J Thorac Cardiovasc Surg (2009) 1.28
A critical role of the adenosine A2A receptor in extrastriatal neurons in modulating psychomotor activity as revealed by opposite phenotypes of striatum and forebrain A2A receptor knock-outs. J Neurosci (2008) 1.27
CD73 is expressed by human regulatory T helper cells and suppresses proinflammatory cytokine production and Helicobacter felis-induced gastritis in mice. J Infect Dis (2009) 1.25
Adenosine A2A receptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms. Ann Neurol (2008) 1.24
Adenosine A2A receptor activation reduces inflammation and preserves pulmonary function in an in vivo model of lung transplantation. J Thorac Cardiovasc Surg (2005) 1.22
Adenosine A2A receptor activation on CD4+ T lymphocytes and neutrophils attenuates lung ischemia-reperfusion injury. J Thorac Cardiovasc Surg (2009) 1.17
P-selectin-mediated platelet-neutrophil aggregate formation activates neutrophils in mouse and human sickle cell disease. Arterioscler Thromb Vasc Biol (2010) 1.17
Macrolide- and rifampin-resistant Rhodococcus equi on a horse breeding farm, Kentucky, USA. Emerg Infect Dis (2013) 1.16
Inactivation of the adenosine A2A receptor protects apolipoprotein E-deficient mice from atherosclerosis. Arterioscler Thromb Vasc Biol (2009) 1.14
The A2B adenosine receptor promotes Th17 differentiation via stimulation of dendritic cell IL-6. J Immunol (2011) 1.13
The role of adenosine A2A receptor signaling in bronchiolitis obliterans. Ann Thorac Surg (2009) 1.13
Purinergic regulation of epithelial transport. J Physiol (2003) 1.13
Real-time reverse transcription-PCR assay for detection of mumps virus RNA in clinical specimens. J Clin Microbiol (2007) 1.13
Adenosine signaling via the adenosine 2B receptor is involved in bronchiolitis obliterans development. J Heart Lung Transplant (2010) 1.12
Activation of adenosine 2A receptors preserves structure and function of podocytes. J Am Soc Nephrol (2007) 1.12
Activation of A2A adenosine receptors inhibits expression of alpha 4/beta 1 integrin (very late antigen-4) on stimulated human neutrophils. J Leukoc Biol (2003) 1.11
A crucial role for forebrain adenosine A(2A) receptors in amphetamine sensitization. Neuropsychopharmacology (2005) 1.10
Leukocyte compartments in the mouse lung: distinguishing between marginated, interstitial, and alveolar cells in response to injury. J Immunol Methods (2011) 1.09
Targeting iNKT cells for the treatment of sickle cell disease. Clin Immunol (2011) 1.09
Reduction of infarct size and postischemic inflammation from ATL-146e, a highly selective adenosine A2A receptor agonist, in reperfused canine myocardium. Am J Physiol Heart Circ Physiol (2004) 1.08
Adenosine A₂A agonist improves lung function during ex vivo lung perfusion. Ann Thorac Surg (2011) 1.07
Sickle cell vaso-occlusion causes activation of iNKT cells that is decreased by the adenosine A2A receptor agonist regadenoson. Blood (2013) 1.07
Links between insulin resistance, adenosine A2B receptors, and inflammatory markers in mice and humans. Diabetes (2011) 1.06
After treat-to-target: can a targeted ultrasound initiative improve RA outcomes? Ann Rheum Dis (2012) 1.04
An A2A adenosine receptor agonist, ATL313, reduces inflammation and improves survival in murine sepsis models. BMC Infect Dis (2008) 1.02
Adenosine A2A receptor activation reduces infarct size in the isolated, perfused mouse heart by inhibiting resident cardiac mast cell degranulation. Am J Physiol Heart Circ Physiol (2008) 1.02
Differential induction of MyD88- and TRIF-dependent pathways in equine monocytes by Toll-like receptor agonists. Vet Immunol Immunopathol (2008) 1.01
Activation of A1, A2A, or A3 adenosine receptors attenuates lung ischemia-reperfusion injury. J Thorac Cardiovasc Surg (2010) 1.01
Neonatal immune development in the calf and its impact on vaccine response. Vet Clin North Am Food Anim Pract (2008) 1.00
Synthesis and biological evaluation of Rhizobium sin-1 lipid A derivatives. J Am Chem Soc (2003) 1.00
A1 adenosine receptor activation promotes angiogenesis and release of VEGF from monocytes. Circ Res (2007) 1.00
Adenosine A2B receptors are highly expressed on murine type II alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol (2009) 1.00
Optimization of a mouse locomotor rating system to evaluate compression-induced spinal cord injury: correlation of locomotor and morphological injury indices. J Neurosurg Spine (2006) 0.99
Diagnostic and therapeutic strategies for small abdominal aortic aneurysms. Nat Rev Cardiol (2011) 0.97
Adenosine A2A receptor activation limits graft-versus-host disease after allogenic hematopoietic stem cell transplantation. J Leukoc Biol (2009) 0.96
Carnitine palmitoyltransferase 1A (CPT1A) P479L prevalence in live newborns in Yukon, Northwest Territories, and Nunavut. Mol Genet Metab (2010) 0.96
Allosteric enhancers of A1 adenosine receptors increase receptor-G protein coupling and counteract Guanine nucleotide effects on agonist binding. Mol Pharmacol (2003) 0.96
Statin's excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling. J Neurosci (2009) 0.96
Rapid modification of the glycocalyx caused by ischemia-reperfusion is inhibited by adenosine A2A receptor activation. Am J Physiol Heart Circ Physiol (2003) 0.95
Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions. J Med Chem (2002) 0.95
2-Amino-3-aroyl-4,5-alkylthiophenes: agonist allosteric enhancers at human A(1) adenosine receptors. J Med Chem (2002) 0.94
Innate immune responses of primary murine macrophage-lineage cells and RAW 264.7 cells to ligands of Toll-like receptors 2, 3, and 4. Comp Immunol Microbiol Infect Dis (2009) 0.94
Adenosine A2A receptor signaling and golf assembly show a specific requirement for the gamma7 subtype in the striatum. J Biol Chem (2010) 0.94
2-aminothienopyridazines as novel adenosine A1 receptor allosteric modulators and antagonists. J Med Chem (2008) 0.94
Synthesis and biological evaluation of a lipid A derivative that contains an aminogluconate moiety. Chemistry (2004) 0.94
Inhibiting CXCL12 blocks fibrocyte migration and differentiation and attenuates bronchiolitis obliterans in a murine heterotopic tracheal transplant model. J Thorac Cardiovasc Surg (2012) 0.93
Antiviral activity of the hepatitis C virus polymerase inhibitor filibuvir in genotype 1-infected patients. Hepatology (2011) 0.93
Adenosine-mediated cardioprotection in ischemic-reperfused mouse heart. J Cardiovasc Pharmacol (2002) 0.93
The equine TLR4/MD-2 complex mediates recognition of lipopolysaccharide from Rhodobacter sphaeroides as an agonist. J Endotoxin Res (2007) 0.92
Quinazolines as adenosine receptor antagonists: SAR and selectivity for A2B receptors. Bioorg Med Chem (2003) 0.92
Protection from pulmonary ischemia-reperfusion injury by adenosine A2A receptor activation. Respir Res (2009) 0.92
Exercise-induced alterations in pro-inflammatory cytokines and prostaglandin F2alpha in horses. Vet Immunol Immunopathol (2007) 0.91
Adenosine A(2B) receptor deficiency promotes host defenses against gram-negative bacterial pneumonia. Am J Respir Crit Care Med (2012) 0.91