Published in FASEB J on January 07, 2010
The chitinase-like protein YKL-40 is secreted by airway epithelial cells at base line and in response to compressive mechanical stress. J Biol Chem (2010) 1.03
miR-146a regulates mechanotransduction and pressure-induced inflammation in small airway epithelium. FASEB J (2012) 0.99
Ion Electrodiffusion Governs Silk Electrogelation. Soft Matter (2012) 0.93
YAP forms autocrine loops with the ERBB pathway to regulate ovarian cancer initiation and progression. Oncogene (2015) 0.92
A 3-D model of ligand transport in a deforming extracellular space. Biophys J (2010) 0.91
TNF-α-converting enzyme/a disintegrin and metalloprotease-17 mediates mechanotransduction in murine tracheal epithelial cells. Am J Respir Cell Mol Biol (2010) 0.89
Putting the Squeeze on Airway Epithelia. Physiology (Bethesda) (2015) 0.86
Cell Jamming in the Airway Epithelium. Ann Am Thorac Soc (2016) 0.80
Mechanobiology in lung epithelial cells: measurements, perturbations, and responses. Compr Physiol (2012) 0.80
Coming to terms with tissue engineering and regenerative medicine in the lung. Am J Physiol Lung Cell Mol Physiol (2015) 0.78
Hypercapnia attenuates ventilator-induced lung injury via a disintegrin and metalloprotease-17. J Physiol (2014) 0.76
Oleanolic acid induces migration in Mv1Lu and MDA-MB-231 epithelial cells involving EGF receptor and MAP kinases activation. PLoS One (2017) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics (2003) 100.88
DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol (2003) 84.79
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med (2004) 71.08
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell (2006) 20.92
Biphasic creep and stress relaxation of articular cartilage in compression? Theory and experiments. J Biomech Eng (1980) 7.76
Force sensing by mechanical extension of the Src family kinase substrate p130Cas. Cell (2006) 7.35
EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature (2000) 7.03
A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature (2005) 6.86
Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors. Nat Biotechnol (2002) 6.68
Autocrine growth factors and cancer. Nature (1985) 5.97
Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics. Nat Biotechnol (2004) 5.22
Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases. Oncogene (2007) 4.80
Visualizing the mechanical activation of Src. Nature (2005) 4.63
A triphasic theory for the swelling and deformation behaviors of articular cartilage. J Biomech Eng (1991) 4.61
A module of negative feedback regulators defines growth factor signaling. Nat Genet (2007) 4.35
Prediction and validation of the distinct dynamics of transient and sustained ERK activation. Nat Cell Biol (2005) 4.13
Segregation of receptor and ligand regulates activation of epithelial growth factor receptor. Nature (2003) 3.61
EGF receptor ligands. Exp Cell Res (2003) 3.60
Normal and cystic fibrosis airway surface liquid homeostasis. The effects of phasic shear stress and viral infections. J Biol Chem (2005) 3.08
Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels. J Cell Sci (2006) 2.98
Dual-specificity MAP kinase phosphatases (MKPs) and cancer. Cancer Metastasis Rev (2008) 2.94
Spred is a Sprouty-related suppressor of Ras signalling. Nature (2001) 2.87
Computational modeling of the EGF-receptor system: a paradigm for systems biology. Trends Cell Biol (2003) 2.85
Epidermal growth factor system regulates mucin production in airways. Proc Natl Acad Sci U S A (1999) 2.57
EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation. Nat Cell Biol (2003) 2.49
Mechanotransduction through growth-factor shedding into the extracellular space. Nature (2004) 2.48
Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine/paracrine mechanism. EMBO J (1993) 2.44
EGFR signal transactivation in cancer cells. Biochem Soc Trans (2003) 2.42
Involvement of the epidermal growth factor receptor in epithelial repair in asthma. FASEB J (2000) 2.42
Regulation of normal and cystic fibrosis airway surface liquid volume by phasic shear stress. Annu Rev Physiol (2006) 2.33
Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals. J Clin Invest (2006) 2.33
IL-13 and epidermal growth factor receptor have critical but distinct roles in epithelial cell mucin production. Am J Respir Cell Mol Biol (2006) 2.29
G protein-coupled receptors sense fluid shear stress in endothelial cells. Proc Natl Acad Sci U S A (2006) 2.21
Heparin-binding EGF-like growth factor. Biochim Biophys Acta (1997) 2.19
An integrated model of epidermal growth factor receptor trafficking and signal transduction. Biophys J (2003) 1.80
Bronchial epithelial compression regulates epidermal growth factor receptor family ligand expression in an autocrine manner. Am J Respir Cell Mol Biol (2005) 1.79
Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatases. Trends Cell Biol (2001) 1.73
Cellular mechanics and gene expression in blood vessels. J Biomech (2003) 1.63
Controlling epidermal growth factor (EGF)-stimulated Ras activation in intact cells by a cell-permeable peptide mimicking phosphorylated EGF receptor. J Biol Chem (1996) 1.61
Differential effects of cyclic and constant stress on ATP release and mucociliary transport by human airway epithelia. J Physiol (2007) 1.57
Relationship of epidermal growth factor receptors to goblet cell production in human bronchi. Am J Respir Crit Care Med (2001) 1.54
The effects of matrix stiffness and RhoA on the phenotypic plasticity of smooth muscle cells in a 3-D biosynthetic hydrogel system. Biomaterials (2008) 1.51
Expression of epidermal growth factor and epidermal growth factor receptor immunoreactivity in the asthmatic human airway. Am J Respir Crit Care Med (1998) 1.48
Characterization of collagen gel solutions and collagen matrices for cell culture. Biomaterials (2001) 1.44
Linearity and time-scale invariance of the creep function in living cells. J R Soc Interface (2004) 1.42
Bronchial epithelial compression regulates MAP kinase signaling and HB-EGF-like growth factor expression. Am J Physiol Lung Cell Mol Physiol (2002) 1.40
On the mechanism of mucosal folding in normal and asthmatic airways. J Appl Physiol (1985) (1997) 1.38
Mechanical stress triggers selective release of fibrotic mediators from bronchial epithelium. Am J Respir Cell Mol Biol (2003) 1.36
Cardiomyocyte hypertrophy and degradation of connexin43 through spatially restricted autocrine/paracrine heparin-binding EGF. Proc Natl Acad Sci U S A (2005) 1.36
Profiling receptor tyrosine kinase activation by using Ab microarrays. Proc Natl Acad Sci U S A (2003) 1.36
Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors. Oncogene (2006) 1.34
Impaired lung branching morphogenesis in the absence of functional EGF receptor. Dev Biol (1997) 1.29
Identification of genes expressed with temporal-spatial restriction to developing cerebellar neuron precursors by a functional genomic approach. Proc Natl Acad Sci U S A (2002) 1.27
Size and shape of the lateral intercellular spaces in a living epithelium. Science (1978) 1.26
The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma. Clin Exp Allergy (2003) 1.25
The correspondence between equilibrium biphasic and triphasic material properties in mixture models of articular cartilage. J Biomech (2004) 1.24
Pressure-volume and length-stress relationships in canine bronchi in vitro. J Appl Physiol (1985) (1988) 1.24
Basolateral targeting and efficient consumption of transforming growth factor-alpha when expressed in Madin-Darby canine kidney cells. J Biol Chem (1994) 1.22
Expression of c-erbB receptors and ligands in human bronchial mucosa. Am J Respir Cell Mol Biol (1999) 1.18
Gene expression profiling of Duchenne muscular dystrophy skeletal muscle. Neurogenetics (2003) 1.18
Differentiation-dependent responsiveness of bronchial epithelial cells to IL-4/13 stimulation. Am J Physiol Lung Cell Mol Physiol (2004) 1.17
Real-time quantitative measurement of autocrine ligand binding indicates that autocrine loops are spatially localized. Proc Natl Acad Sci U S A (1998) 1.13
Expression of c-erbB receptors and ligands in the bronchial epithelium of asthmatic subjects. J Allergy Clin Immunol (2002) 1.13
Chronic effects of mechanical force on airways. Annu Rev Physiol (2006) 1.11
Molecular responses of rat tracheal epithelial cells to transmembrane pressure. Am J Physiol Lung Cell Mol Physiol (2000) 1.10
Chronic intermittent mechanical stress increases MUC5AC protein expression. Am J Respir Cell Mol Biol (2009) 1.09
Differential regulation of vascular focal adhesion kinase by steady stretch and pulsatility. Circulation (2005) 1.05
Induction of the plasminogen activator system by mechanical stimulation of human bronchial epithelial cells. Am J Respir Cell Mol Biol (2006) 1.04
Contribution of the cytoskeleton to the compressive properties and recovery behavior of single cells. Biophys J (2009) 1.03
Computational modeling of extracellular mechanotransduction. Biophys J (2006) 1.02
Diffusion coefficients in the lateral intercellular spaces of Madin-Darby canine kidney cell epithelium determined with caged compounds. Biophys J (1998) 0.95
Distribution of epidermal growth factor and epidermal growth factor receptor in human lung: immunohistochemical and immunoelectron-microscopic studies. Respiration (1994) 0.93
Up-regulation of thrombospondin-1 gene by epidermal growth factor and transforming growth factor beta in human cancer cells--transcriptional activation and messenger RNA stabilization. Biochim Biophys Acta (2002) 0.91
Protein-tyrosine phosphatase-mediated decrease of epidermal growth factor and platelet-derived growth factor receptor tyrosine phosphorylation in high cell density cultures. J Biol Chem (1996) 0.87
Diffusion of small solutes in the lateral intercellular spaces of MDCK cell epithelium grown on permeable supports. J Membr Biol (2000) 0.83
Quantification of three-dimensional dynamics of intercellular geometry under mechanical loading using a weighted directional adaptive-threshold method. Opt Express (2008) 0.83
Epidermal growth factor dependence and TGF alpha autocrine growth regulation in primary rat tracheal epithelial cells. J Cell Physiol (1992) 0.79
A model for mechanotransduction in cardiac muscle: effects of extracellular matrix deformation on autocrine signaling. Ann Biomed Eng (2004) 0.79
Plasma vascular endothelial growth factor and interleukin-8 as biomarkers of antitumor efficacy of a prototypical erbB family tyrosine kinase inhibitor. Mol Cancer Ther (2005) 0.77
Dynamic behavior of lung parenchyma in shear. J Appl Physiol (1985) (1996) 0.77
Universal physical responses to stretch in the living cell. Nature (2007) 4.72
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma. Cancer Cell (2008) 4.68
BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors. Cancer Discov (2011) 3.34
Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression. J Cell Biol (2010) 2.96
The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas. J Neuropathol Exp Neurol (2004) 2.66
Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell (2013) 2.64
Gene expression comparison of biopsies from Duchenne muscular dystrophy (DMD) and normal skeletal muscle. Proc Natl Acad Sci U S A (2002) 2.60
Mechanotransduction through growth-factor shedding into the extracellular space. Nature (2004) 2.48
The biology of brain metastases-translation to new therapies. Nat Rev Clin Oncol (2011) 2.16
Clustered dynamics of inhibitory synapses and dendritic spines in the adult neocortex. Neuron (2012) 2.10
In vivo wide-area cellular imaging by side-view endomicroscopy. Nat Methods (2010) 2.10
Bronchial epithelial compression regulates epidermal growth factor receptor family ligand expression in an autocrine manner. Am J Respir Cell Mol Biol (2005) 1.79
Matrix rigidity regulates cancer cell growth and cellular phenotype. PLoS One (2010) 1.70
Propulsion and navigation within the advancing monolayer sheet. Nat Mater (2013) 1.70
Two-dimensional standing wave total internal reflection fluorescence microscopy: superresolution imaging of single molecular and biological specimens. Biophys J (2007) 1.53
High-resolution whole organ imaging using two-photon tissue cytometry. J Biomed Opt (2007) 1.50
Defective ribosomal protein gene expression alters transcription, translation, apoptosis, and oncogenic pathways in Diamond-Blackfan anemia. Stem Cells (2006) 1.46
Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin. J Cell Biol (2006) 1.42
Three-dimensional image cytometer based on widefield structured light microscopy and high-speed remote depth scanning. Cytometry A (2014) 1.42
Multiphoton autofluorescence and second-harmonic generation imaging of the ex vivo porcine eye. Invest Ophthalmol Vis Sci (2006) 1.40
Expression profiling reveals altered satellite cell numbers and glycolytic enzyme transcription in nemaline myopathy muscle. Proc Natl Acad Sci U S A (2003) 1.29
Multifocal multiphoton microscopy based on multianode photomultiplier tubes. Opt Express (2007) 1.28
Two-photon 3-D mapping of ex vivo human skin endogenous fluorescence species based on fluorescence emission spectra. J Biomed Opt (2005) 1.26
Matrix stiffness reverses the effect of actomyosin tension on cell proliferation. J Cell Sci (2012) 1.23
Improved throughput traction microscopy reveals pivotal role for matrix stiffness in fibroblast contractility and TGF-β responsiveness. Am J Physiol Lung Cell Mol Physiol (2012) 1.22
Micro-mechanical characterization of lung tissue using atomic force microscopy. J Vis Exp (2011) 1.22
Predicting survival within the lung cancer histopathological hierarchy using a multi-scale genomic model of development. PLoS Med (2006) 1.21
A multiwell platform for studying stiffness-dependent cell biology. PLoS One (2011) 1.21
Single-photon counting multicolor multiphoton fluorescence microscope. J Fluoresc (2005) 1.21
Modeling intrinsically disordered proteins with bayesian statistics. J Am Chem Soc (2010) 1.20
Gene expression profiling of Duchenne muscular dystrophy skeletal muscle. Neurogenetics (2003) 1.18
Differentiation-dependent responsiveness of bronchial epithelial cells to IL-4/13 stimulation. Am J Physiol Lung Cell Mol Physiol (2004) 1.17
Expression analysis of asthma candidate genes during human and murine lung development. Respir Res (2011) 1.16
Differentiation of normal and cancerous lung tissues by multiphoton imaging. J Biomed Opt (2009) 1.14
Improvement of axial resolution and contrast in temporally focused widefield two-photon microscopy with structured light illumination. Biomed Opt Express (2013) 1.13
Three-dimensional cellular deformation analysis with a two-photon magnetic manipulator workstation. Biophys J (2002) 1.12
Three-dimensional tissue cytometer based on high-speed multiphoton microscopy. Cytometry A (2007) 1.11
A new microrheometric approach reveals individual and cooperative roles for TGF-beta1 and IL-1beta in fibroblast-mediated stiffening of collagen gels. FASEB J (2007) 1.11
Shack-Hartmann wavefront-sensor-based adaptive optics system for multiphoton microscopy. J Biomed Opt (2010) 1.10
Antecedents of two-photon excitation laser scanning microscopy. Microsc Res Tech (2004) 1.10
Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases. Proc Natl Acad Sci U S A (2012) 1.09
Chronic intermittent mechanical stress increases MUC5AC protein expression. Am J Respir Cell Mol Biol (2009) 1.09
Matrices of physiologic stiffness potently inactivate idiopathic pulmonary fibrosis fibroblasts. Am J Respir Cell Mol Biol (2013) 1.08
Variations in gene expression among different types of human skeletal muscle. Muscle Nerve (2005) 1.07
Feasibility of in vivo imaging of fluorescent proteins using lifetime contrast. Opt Lett (2009) 1.07
Multifunctional imaging of endogenous contrast by simultaneous nonlinear and optical coherence microscopy of thick tissues. Microsc Res Tech (2007) 1.06
Fibro-C-Index: comprehensive, morphology-based quantification of liver fibrosis using second harmonic generation and two-photon microscopy. J Biomed Opt (2009) 1.06
Cell elasticity determines macrophage function. PLoS One (2012) 1.05
Mitigating thermal mechanical damage potential during two-photon dermal imaging. J Biomed Opt (2004) 1.04
Induction of the plasminogen activator system by mechanical stimulation of human bronchial epithelial cells. Am J Respir Cell Mol Biol (2006) 1.04
Transcriptional regulation differs in affected facioscapulohumeral muscular dystrophy patients compared to asymptomatic related carriers. Proc Natl Acad Sci U S A (2009) 1.04
The chitinase-like protein YKL-40 is secreted by airway epithelial cells at base line and in response to compressive mechanical stress. J Biol Chem (2010) 1.03
Computational modeling of extracellular mechanotransduction. Biophys J (2006) 1.02
High-throughput three-dimensional lithographic microfabrication. Opt Lett (2010) 1.02
Melanoma cell adhesion molecule is a novel marker for human fetal myogenic cells and affects myoblast fusion. J Cell Sci (2006) 1.01
The influence of muscle type and dystrophin deficiency on murine expression profiles. Mamm Genome (2005) 1.00
Comparing the quantification of Forster resonance energy transfer measurement accuracies based on intensity, spectral, and lifetime imaging. J Biomed Opt (2006) 1.00
Dual-channel two-photon microscopy study of transdermal transport in skin treated with low-frequency ultrasound and a chemical enhancer. J Invest Dermatol (2007) 1.00
Matrix rigidity regulates cancer cell growth by modulating cellular metabolism and protein synthesis. PLoS One (2012) 0.99
The challenge of connecting the dots in the B.R.A.I.N. Neuron (2013) 0.99
Investigating mechanisms of collagen thermal denaturation by high resolution second-harmonic generation imaging. Biophys J (2006) 0.98
TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice. J Clin Invest (2014) 0.98
Matrix stiffness corresponding to strictured bowel induces a fibrogenic response in human colonic fibroblasts. Inflamm Bowel Dis (2013) 0.97
Vitamin D related genes in lung development and asthma pathogenesis. BMC Med Genomics (2013) 0.95
Video-rate resonant scanning multiphoton microscopy: An emerging technique for intravital imaging of the tumor microenvironment. Intravital (2012) 0.93
Extended resolution wide-field optical imaging: objective-launched standing-wave total internal reflection fluorescence microscopy. Opt Lett (2006) 0.93
Ultrafast optical pulse delivery with fibers for nonlinear microscopy. Microsc Res Tech (2008) 0.92
Residual structure within the disordered C-terminal segment of p21(Waf1/Cip1/Sdi1) and its implications for molecular recognition. Protein Sci (2009) 0.92
Diffraction optical tomography using a quantitative phase imaging unit. Opt Lett (2014) 0.92
Mass spectrometry-based study of the plasma proteome in a mouse intestinal tumor model. J Proteome Res (2006) 0.92
Common features of optimal collagen scaffolds that disrupt wound contraction and enhance regeneration both in peripheral nerves and in skin. Biomaterials (2012) 0.92
A 3-D model of ligand transport in a deforming extracellular space. Biophys J (2010) 0.91
Quantifying the dynamics of bacterial secondary metabolites by spectral multiphoton microscopy. ACS Chem Biol (2011) 0.90
Fast fluorescence laser tracking microrheometry, II: quantitative studies of cytoskeletal mechanotransduction. Biophys J (2008) 0.90
Tissue factor-bearing exosome secretion from human mechanically stimulated bronchial epithelial cells in vitro and in vivo. J Allergy Clin Immunol (2012) 0.90
Fast fluorescence laser tracking microrheometry. I: instrument development. Biophys J (2007) 0.90
Low prevalence of transmitted K65R and other tenofovir resistance mutations across different HIV-1 subtypes: implications for pre-exposure prophylaxis. J Int AIDS Soc (2012) 0.89
Three dimensional HiLo-based structured illumination for a digital scanned laser sheet microscopy (DSLM) in thick tissue imaging. Opt Express (2012) 0.89
3D-resolved fluorescence and phosphorescence lifetime imaging using temporal focusing wide-field two-photon excitation. Opt Express (2012) 0.89
Performances of high numerical aperture water and oil immersion objective in deep-tissue, multi-photon microscopic imaging of excised human skin. Microsc Res Tech (2004) 0.89
Dynamic speckle illumination wide-field reflection phase microscopy. Opt Lett (2014) 0.89
TNF-α-converting enzyme/a disintegrin and metalloprotease-17 mediates mechanotransduction in murine tracheal epithelial cells. Am J Respir Cell Mol Biol (2010) 0.89
Stretch-induced mitogen-activated protein kinase activation in lung fibroblasts is independent of receptor tyrosine kinases. Am J Respir Cell Mol Biol (2009) 0.88
Cell stiffness and receptors: evidence for cytoskeletal subnetworks. Am J Physiol Cell Physiol (2004) 0.88
Cerebellar 'transcriptome' reveals cell-type and stage-specific expression during postnatal development and tumorigenesis. Mol Cell Neurosci (2006) 0.88
Multiscale structural analysis of mouse lingual myoarchitecture employing diffusion spectrum magnetic resonance imaging and multiphoton microscopy. J Biomed Opt (2009) 0.87
Quantitative morphometric measurements using site selective image cytometry of intact tissue. J R Soc Interface (2009) 0.86
Integrated one- and two-photon imaging platform reveals clonal expansion as a major driver of mutation load. Proc Natl Acad Sci U S A (2008) 0.86
(R)-albuterol elicits antiinflammatory effects in human airway epithelial cells via iNOS. Am J Respir Cell Mol Biol (2005) 0.86
Soft matrix is a natural stimulator for cellular invasiveness. Mol Biol Cell (2013) 0.86
Frequency domain lifetime and spectral imaging microscopy. Microsc Res Tech (2006) 0.85
An optical method to quantify the density of ligands for cell adhesion receptors in three-dimensional matrices. J R Soc Interface (2010) 0.85
Toward surface quantification of liver fibrosis progression. J Biomed Opt (2010) 0.85
Temporally focused wide-field two-photon microscopy: paraxial to vectorial. Opt Express (2013) 0.85
Intact corneal stroma visualization of GFP mouse revealed by multiphoton imaging. Microsc Res Tech (2006) 0.85