Published in Acta Crystallogr Sect F Struct Biol Cryst Commun on December 25, 2009
Structural characterization of binding mode of smoking cessation drugs to nicotinic acetylcholine receptors through study of ligand complexes with acetylcholine-binding protein. J Biol Chem (2012) 0.98
Arabidopsis stromal-derived Factor2 (SDF2) is a crucial target of the unfolded protein response in the endoplasmic reticulum. J Biol Chem (2010) 0.87
The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr (1994) 187.88
Solvent content of protein crystals. J Mol Biol (1968) 106.07
Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol (2007) 33.06
Empirical analysis of transcriptional activity in the Arabidopsis genome. Science (2003) 11.62
A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins. Mol Biol Cell (2002) 3.56
Genomic analysis of the unfolded protein response in Arabidopsis shows its connection to important cellular processes. Plant Cell (2003) 2.94
Structure of the inositol 1,4,5-trisphosphate receptor binding core in complex with its ligand. Nature (2002) 2.30
Crystal structure of the ligand binding suppressor domain of type 1 inositol 1,4,5-trisphosphate receptor. Mol Cell (2005) 1.62
Endoplasmic reticulum quality control and the unfolded protein response: insights from plants. Traffic (2008) 1.57
Gene expression in response to endoplasmic reticulum stress in Arabidopsis thaliana. FEBS J (2005) 1.53
Murine and human SDF2L1 is an endoplasmic reticulum stress-inducible gene and encodes a new member of the Pmt/rt protein family. Biochem Biophys Res Commun (2001) 1.11
Novel repeats in ryanodine and IP3 receptors and protein O-mannosyltransferases. Trends Biochem Sci (2000) 1.05
Isolation and characterization of a novel secretory protein, stromal cell-derived factor-2 (SDF-2) using the signal sequence trap method. Gene (1996) 1.00
Characterization of pancreatic ERj3p, a homolog of yeast DnaJ-like protein Scj1p. Biol Chem (2004) 0.95
Following the signal sequence from ribosomal tunnel exit to signal recognition particle. Nature (2006) 2.11
Distinct modes of signal recognition particle interaction with the ribosome. Science (2002) 2.08
Delivering proteins for export from the cytosol. Nat Rev Mol Cell Biol (2009) 2.00
ISPD loss-of-function mutations disrupt dystroglycan O-mannosylation and cause Walker-Warburg syndrome. Nat Genet (2012) 1.93
High-resolution X-ray and NMR structures of the SMN Tudor domain: conformational variation in the binding site for symmetrically dimethylated arginine residues. J Mol Biol (2003) 1.84
Structure and dynamics of the ATP-bound open conformation of Hsp70 chaperones. Mol Cell (2012) 1.84
Protein glycosylation, conserved from yeast to man: a model organism helps elucidate congenital human diseases. Angew Chem Int Ed Engl (2006) 1.83
Signal recognition particle receptor exposes the ribosomal translocon binding site. Science (2006) 1.77
Signal peptide peptidase (SPP) assembles with substrates and misfolded membrane proteins into distinct oligomeric complexes. Biochem J (2010) 1.68
Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex. Science (2011) 1.68
Structural insights into tail-anchored protein binding and membrane insertion by Get3. Proc Natl Acad Sci U S A (2009) 1.63
Membrane curvature induced by Arf1-GTP is essential for vesicle formation. Proc Natl Acad Sci U S A (2008) 1.63
SRP-mediated protein targeting: structure and function revisited. Biochim Biophys Acta (2004) 1.57
Crystal structure of the complete core of archaeal signal recognition particle and implications for interdomain communication. Proc Natl Acad Sci U S A (2003) 1.55
The structure of a pH-sensing mycobacterial adenylyl cyclase holoenzyme. Science (2005) 1.52
Substrate binding disrupts dimerization and induces nucleotide exchange of the chloroplast GTPase Toc33. Biochem J (2011) 1.49
The C terminus of the Alb3 membrane insertase recruits cpSRP43 to the thylakoid membrane. J Biol Chem (2009) 1.49
O-mannosyl glycans: from yeast to novel associations with human disease. Curr Opin Struct Biol (2003) 1.47
Signal recognition particle mediates post-translational targeting in eukaryotes. EMBO J (2004) 1.46
Members of the evolutionarily conserved PMT family of protein O-mannosyltransferases form distinct protein complexes among themselves. J Biol Chem (2003) 1.42
Protein O-mannosylation: conserved from bacteria to humans. Glycobiology (2009) 1.42
Protein targeting by the signal recognition particle. Biol Chem (2009) 1.39
Molecular basis for the unique role of the AAA+ chaperone ClpV in type VI protein secretion. J Biol Chem (2011) 1.37
FlhA provides the adaptor for coordinated delivery of late flagella building blocks to the type III secretion system. Proc Natl Acad Sci U S A (2010) 1.35
Targeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethality. Proc Natl Acad Sci U S A (2004) 1.35
Characterization of POMT2, a novel member of the PMT protein O-mannosyltransferase family specifically localized to the acrosome of mammalian spermatids. Glycobiology (2002) 1.34
A direct role for phosphatidylinositol-4,5-bisphosphate in unconventional secretion of fibroblast growth factor 2. Traffic (2008) 1.33
Aberrant processing of the WSC family and Mid2p cell surface sensors results in cell death of Saccharomyces cerevisiae O-mannosylation mutants. Mol Cell Biol (2004) 1.32
Canonical signal recognition particle components can be bypassed for posttranslational protein targeting in chloroplasts. Plant Cell (2007) 1.31
SRP meets the ribosome. Nat Struct Mol Biol (2004) 1.18
Escherichia coli signal recognition particle receptor FtsY contains an essential and autonomous membrane-binding amphipathic helix. J Biol Chem (2007) 1.17
Structural basis for specific substrate recognition by the chloroplast signal recognition particle protein cpSRP43. Science (2008) 1.15
Structure of a bacterial pyridoxal 5'-phosphate synthase complex. Proc Natl Acad Sci U S A (2006) 1.14
The structure of the mammalian signal recognition particle (SRP) receptor as prototype for the interaction of small GTPases with Longin domains. J Biol Chem (2006) 1.14
Protein O-mannosylation is crucial for cell wall integrity, septation and viability in fission yeast. Mol Microbiol (2005) 1.13
Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2. EMBO Rep (2008) 1.13
Protein O-mannosylation is crucial for E-cadherin-mediated cell adhesion. Proc Natl Acad Sci U S A (2013) 1.13
Glutamate-binding affinity of Drosophila metabotropic glutamate receptor is modulated by association with lipid rafts. Proc Natl Acad Sci U S A (2003) 1.10
Members of protein O-mannosyltransferase family in Aspergillus fumigatus differentially affect growth, morphogenesis and viability. Mol Microbiol (2010) 1.09
Vitamin B6 biosynthesis by the malaria parasite Plasmodium falciparum: biochemical and structural insights. J Biol Chem (2005) 1.05
Membrane association is a determinant for substrate recognition by PMT4 protein O-mannosyltransferases. Proc Natl Acad Sci U S A (2007) 1.05
cpSRP43 is a novel chaperone specific for light-harvesting chlorophyll a,b-binding proteins. J Biol Chem (2010) 1.05
O-mannosylation precedes and potentially controls the N-glycosylation of a yeast cell wall glycoprotein. EMBO Rep (2003) 1.04
The crystal structure of Ebp1 reveals a methionine aminopeptidase fold as binding platform for multiple interactions. FEBS Lett (2007) 1.04
Structural analysis of the human Golgi-associated plant pathogenesis related protein GAPR-1 implicates dimerization as a regulatory mechanism. J Mol Biol (2004) 1.04
The GTPase cycle of the chloroplast import receptors Toc33/Toc34: implications from monomeric and dimeric structures. Structure (2008) 1.03
The structure of Get4 reveals an alpha-solenoid fold adapted for multiple interactions in tail-anchored protein biogenesis. FEBS Lett (2010) 1.03
Structural characterization of a eukaryotic chaperone--the ribosome-associated complex. Nat Struct Mol Biol (2012) 1.03
Reconstituted TOM core complex and Tim9/Tim10 complex of mitochondria are sufficient for translocation of the ADP/ATP carrier across membranes. Mol Biol Cell (2003) 1.02
Functional and genomic analyses of blocked protein O-mannosylation in baker's yeast. Mol Microbiol (2011) 1.02
Synchronizing nuclear import of ribosomal proteins with ribosome assembly. Science (2012) 1.02
Protein O-mannosylation: what we have learned from baker's yeast. Biochim Biophys Acta (2013) 1.01
Membrane targeting of ribosomes and their release require distinct and separable functions of FtsY. J Biol Chem (2007) 0.98
Towards the structure of the mammalian signal recognition particle. Curr Opin Struct Biol (2002) 0.97
The crystal structure of the periplasmic domain of the Escherichia coli membrane protein insertase YidC contains a substrate binding cleft. J Biol Chem (2008) 0.97
A structural step into the SRP cycle. Mol Microbiol (2004) 0.97
Sed1p and Srl1p are required to compensate for cell wall instability in Saccharomyces cerevisiae mutants defective in multiple GPI-anchored mannoproteins. Mol Microbiol (2004) 0.97
Endoplasmic reticulum targeting and insertion of tail-anchored membrane proteins by the GET pathway. Cold Spring Harb Perspect Biol (2013) 0.96
The crystal structure of the third signal-recognition particle GTPase FlhF reveals a homodimer with bound GTP. Proc Natl Acad Sci U S A (2007) 0.96
Structural basis for the molecular evolution of SRP-GTPase activation by protein. Nat Struct Mol Biol (2011) 0.96
Conserved properties of polypeptide transport-associated (POTRA) domains derived from cyanobacterial Omp85. J Biol Chem (2010) 0.96
An extended helical conformation in domain 3a of Munc18-1 provides a template for SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex assembly. J Biol Chem (2014) 0.93
Protein N-glycosylation determines functionality of the Saccharomyces cerevisiae cell wall integrity sensor Mid2p. Mol Microbiol (2008) 0.91
New twist to nuclear import: When two travel together. Commun Integr Biol (2013) 0.90
Genetic evidence for functional interaction of the Escherichia coli signal recognition particle receptor with acidic lipids in vivo. J Biol Chem (2010) 0.89
Lipids trigger a conformational switch that regulates signal recognition particle (SRP)-mediated protein targeting. J Biol Chem (2011) 0.89
Chromodomains read the arginine code of post-translational targeting. Nat Struct Mol Biol (2012) 0.89
The structure of the chloroplast signal recognition particle (SRP) receptor reveals mechanistic details of SRP GTPase activation and a conserved membrane targeting site. FEBS Lett (2007) 0.89
X-ray crystal structure of Saccharomyces cerevisiae Pdx1 provides insights into the oligomeric nature of PLP synthases. FEBS Lett (2009) 0.89
Consistent mutational paths predict eukaryotic thermostability. BMC Evol Biol (2013) 0.89
O-glycosylation of the non-canonical T-cadherin from rabbit skeletal muscle by single mannose residues. FEBS Lett (2013) 0.88
Choline head groups stabilize the matrix loop regions of the ATP/ADP carrier ScAAC2. Biochem Biophys Res Commun (2003) 0.88
Longin and GAF domains: structural evolution and adaptation to the subcellular trafficking machinery. Traffic (2013) 0.88
Structure and conservation of the periplasmic targeting factor Tic22 protein from plants and cyanobacteria. J Biol Chem (2012) 0.88
Arabidopsis stromal-derived Factor2 (SDF2) is a crucial target of the unfolded protein response in the endoplasmic reticulum. J Biol Chem (2010) 0.87
Crystallization of the crenarchaeal SRP core. Acta Crystallogr D Biol Crystallogr (2003) 0.86
On the significance of Toc-GTPase homodimers. J Biol Chem (2008) 0.86
SIMIBI twins in protein targeting and localization. Nat Struct Mol Biol (2013) 0.86
POMT2, a key enzyme in Walker-Warburg syndrome: somatic sPOMT2, but not testis-specific tPOMT2, is crucial for mannosyltransferase activity in vivo. Glycobiology (2008) 0.86
Scw10p, a cell-wall glucanase/transglucosidase important for cell-wall stability in Saccharomyces cerevisiae. Microbiology (2004) 0.86
A conserved acidic motif is crucial for enzymatic activity of protein O-mannosyltransferases. J Biol Chem (2011) 0.86
Mdm38 is a 14-3-3-like receptor and associates with the protein synthesis machinery at the inner mitochondrial membrane. Traffic (2011) 0.85
SRP RNA remodeling by SRP68 explains its role in protein translocation. Science (2014) 0.85
Assembly of the eukaryotic PLP-synthase complex from Plasmodium and activation of the Pdx1 enzyme. Structure (2012) 0.85
Functional reconstitution of purified metabotropic glutamate receptor expressed in the fly eye. EMBO Rep (2002) 0.85
Overproduction, purification, crystallization and preliminary X-ray analysis of human Fe65-PTB2 in complex with the amyloid precursor protein intracellular domain. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.84
The genetic interaction network of CCW12, a Saccharomyces cerevisiae gene required for cell wall integrity during budding and formation of mating projections. BMC Genomics (2011) 0.84
POMT1 is essential for protein O-mannosylation in mammals. Methods Enzymol (2010) 0.84
Phosphorylation of LRP1 regulates the interaction with Fe65. FEBS Lett (2011) 0.82
Crystal structure of the human Fe65-PTB1 domain. J Biol Chem (2008) 0.82
Pharmacological characterization and immunoaffinity purification of metabotropic glutamate receptor from Drosophila overexpressed in Sf9 cells. Protein Expr Purif (2003) 0.81
The structure of the regulatory domain of the adenylyl cyclase Rv1264 from Mycobacterium tuberculosis with bound oleic acid. J Mol Biol (2007) 0.81
RNA gymnastics in mammalian signal recognition particle assembly. RNA Biol (2014) 0.81
Structural insights into the assembly of the human and archaeal signal recognition particles. Acta Crystallogr D Biol Crystallogr (2010) 0.81
Characterization of Ccw12p, a major key player in cell wall stability of Saccharomyces cerevisiae. Yeast (2007) 0.81
Binding of chloroplast signal recognition particle to a thylakoid membrane protein substrate in aqueous solution and delineation of the cpSRP43-substrate interaction domain. Biochem J (2011) 0.80