Alan Cowan

Author PubWeight™ 34.97‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Comparison of pharmacological activities of three distinct kappa ligands (Salvinorin A, TRK-820 and 3FLB) on kappa opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo. J Pharmacol Exp Ther 2004 1.89
2 Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Mol Pharmacol 2010 1.86
3 A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1. Proc Natl Acad Sci U S A 2005 1.82
4 Buprenorphine: a unique drug with complex pharmacology. Curr Neuropharmacol 2004 1.51
5 2-Methoxymethyl-salvinorin B is a potent kappa opioid receptor agonist with longer lasting action in vivo than salvinorin A. J Pharmacol Exp Ther 2007 1.22
6 Expression of TCTP antisense in CD25(high) regulatory T cells aggravates cuff-injured vascular inflammation. Atherosclerosis 2008 1.05
7 Kappa opioid agonists suppress chloroquine-induced scratching in mice. Eur J Pharmacol 2004 1.05
8 Antinociceptive synergy, additivity, and subadditivity with combinations of oral glucosamine plus nonopioid analgesics in mice. J Pharmacol Exp Ther 2003 1.01
9 Higher expression of Bax in regulatory T cells increases vascular inflammation. Front Biosci 2008 0.98
10 Investigation of gastrin-releasing peptide as a mediator for 5'-guanidinonaltrindole-induced compulsive scratching in mice. Peptides 2010 0.94
11 Nalfurafine, a kappa opioid receptor agonist, inhibits scratching behavior secondary to cholestasis induced by chronic ethynylestradiol injections in rats. Pharmacol Biochem Behav 2006 0.93
12 Abrupt or precipitated withdrawal from morphine induces immunosuppression. J Neuroimmunol 2002 0.93
13 Icilin induces a hyperthermia in rats that is dependent on nitric oxide production and NMDA receptor activation. Eur J Pharmacol 2007 0.91
14 Hyperlocomotion and paw tremors are two highly quantifiable signs of SR141716-precipitated withdrawal from delta9-tetrahydrocannabinol in C57BL/6 mice. Neurosci Lett 2009 0.90
15 Effects of mu, kappa or delta opioids administered by pellet or pump on oral Salmonella infection and gastrointestinal transit. Eur J Pharmacol 2006 0.90
16 Mu and kappa opioid receptor agonists antagonize icilin-induced wet-dog shaking in rats. Eur J Pharmacol 2006 0.86
17 Inhibitory effect of lidocaine on pain and itch using formalin-induced nociception and 5'-guanidinonaltrindole-induced scratching models in mice: behavioral and neuroanatomical evidence. Eur J Pharmacol 2009 0.85
18 Sex difference in κ-opioid receptor (KOPR)-mediated behaviors, brain region KOPR level and KOPR-mediated guanosine 5'-O-(3-[35S]thiotriphosphate) binding in the guinea pig. J Pharmacol Exp Ther 2011 0.85
19 On deriving the dose-effect relation of an unknown second component: an example using buprenorphine preclinical data. Drug Alcohol Depend 2010 0.85
20 Role of TRPV1 and cannabinoid CB1 receptors in AM 404-evoked hypothermia in rats. Pharmacol Biochem Behav 2006 0.83
21 Analgesic efficacy of buprenorphine in the presence of high levels of SDF-1α/CXCL12 in the brain. Drug Alcohol Depend 2010 0.83
22 Characterization of the pharmacokinetics of buprenorphine and norbuprenorphine in rats after intravenous bolus administration of buprenorphine. Eur J Pharm Sci 2002 0.81
23 Icilin-induced wet-dog shakes in rats are dependent on NMDA receptor activation and nitric oxide production. Pharmacol Biochem Behav 2009 0.80
24 Differential antinociceptive effects of buprenorphine and methadone in the presence of HIV-gp120. Drug Alcohol Depend 2011 0.79
25 NMDA receptors modulate morphine-induced hyperthermia. Brain Res 2003 0.78
26 The Analgesic Interaction of Misoprostol with Nonsteroidal Anti-Inflammatory Drugs. Am J Ther 1996 0.78
27 Antipruritic and antihyperalgesic actions of loperamide and analogs. Life Sci 2002 0.78
28 Scratching activates microglia in the mouse spinal cord. J Neurosci Res 2014 0.78
29 Nalfurafine, the kappa opioid agonist, inhibits icilin-induced wet-dog shakes in rats and antagonizes glutamate release in the dorsal striatum. Neuropharmacology 2006 0.78
30 Brain delta2 opioid receptors mediate SNC-80-evoked hypothermia in rats. Brain Res 2005 0.77
31 Modulation of delta opioid-evoked hypothermia in rats by WAY 100635 and fluoxetine. Neurosci Lett 2006 0.76
32 Single millimeter wave treatment does not impair gastrointestinal transit in mice. Life Sci 2002 0.76
33 Reduced kappa-opioid activity in a rat model of cholestasis. Eur J Pharmacol 2005 0.76
34 Icilin-evoked behavioral stimulation is attenuated by alpha₂-adrenoceptor activation. Brain Res 2011 0.75
35 Nitric oxide synthase mediates delta opioid receptor-induced hypothermia in rats. Eur J Pharmacol 2006 0.75
36 Anal itch. Aust Fam Physician 2004 0.75
37 Capsaicin evokes hypothermia independent of cannabinoid CB1 and CB2 receptors. Brain Res 2005 0.75
38 Peripheral kappa-opioid agonist, ICI 204448, evokes hypothermia in cold-exposed rats. Pharmacology 2005 0.75
39 5-HT reuptake and 5-HT2 receptors modulate capsaicin-evoked hypothermia in rats. Neurosci Lett 2007 0.75
40 Preface. Handb Exp Pharmacol 2015 0.75
41 Capsaicin and nitric oxide synthase inhibitor interact to evoke a hypothermic synergy. Neurosci Lett 2006 0.75