Published in Trends Cell Biol on January 12, 2010
The blood-testis barrier and its implications for male contraception. Pharmacol Rev (2011) 2.10
Septin structure and function in yeast and beyond. Trends Cell Biol (2010) 1.99
Sensory neuron fates are distinguished by a transcriptional switch that regulates dendrite branch stabilization. Neuron (2013) 1.77
Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis. Nat Cell Biol (2011) 1.75
The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex. Dev Cell (2010) 1.67
Occludin: one protein, many forms. Mol Cell Biol (2011) 1.53
Inflammation and disintegration of intestinal villi in an experimental model for Vibrio parahaemolyticus-induced diarrhea. PLoS Pathog (2012) 1.47
Telocytes in pleura: two- and three-dimensional imaging by transmission electron microscopy. Cell Tissue Res (2010) 1.45
The diverse roles of Rac signaling in tumorigenesis. Cell Cycle (2011) 1.38
The MDCK variety pack: choosing the right strain. BMC Cell Biol (2011) 1.38
Protein complexes that control renal epithelial polarity. Am J Physiol Renal Physiol (2011) 1.22
Keratin 8 and 18 loss in epithelial cancer cells increases collective cell migration and cisplatin sensitivity through claudin1 up-regulation. J Biol Chem (2013) 1.22
Role of reactive oxygen and nitrogen species in the vascular responses to inflammation. Free Radic Biol Med (2011) 1.17
The Na-K-ATPase α₁β₁ heterodimer as a cell adhesion molecule in epithelia. Am J Physiol Cell Physiol (2012) 1.11
Claudin-16 and claudin-19 function in the thick ascending limb. Curr Opin Nephrol Hypertens (2010) 1.09
Functional ESCRT machinery is required for constitutive recycling of claudin-1 and maintenance of polarity in vertebrate epithelial cells. Mol Biol Cell (2011) 1.09
Tricellulin deficiency affects tight junction architecture and cochlear hair cells. J Clin Invest (2013) 1.09
Differential effects of testosterone and TGF-β3 on endocytic vesicle-mediated protein trafficking events at the blood-testis barrier. Exp Cell Res (2010) 1.08
Epithelial cell adhesion molecule (EpCAM) regulates claudin dynamics and tight junctions. J Biol Chem (2013) 1.06
What is bad in cancer is good in the embryo: importance of EMT in neural crest development. Semin Cell Dev Biol (2012) 1.05
Differential apicobasal VEGF signaling at vascular blood-neural barriers. Dev Cell (2014) 1.00
Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown. PLoS One (2010) 1.00
ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells. Hum Mol Genet (2014) 0.99
Alcohol increases the permeability of airway epithelial tight junctions in Beas-2B and NHBE cells. Alcohol Clin Exp Res (2011) 0.98
Phosphorylation of Rab11-FIP2 regulates polarity in MDCK cells. Mol Biol Cell (2012) 0.98
Allergic sensitization: host-immune factors. Clin Transl Allergy (2014) 0.97
Gene expression correlations in human cancer cell lines define molecular interaction networks for epithelial phenotype. PLoS One (2014) 0.97
β2-syntrophin and Par-3 promote an apicobasal Rac activity gradient at cell-cell junctions by differentially regulating Tiam1 activity. Nat Cell Biol (2012) 0.97
The PIKfyve inhibitor YM201636 blocks the continuous recycling of the tight junction proteins claudin-1 and claudin-2 in MDCK cells. PLoS One (2012) 0.97
Seg1 controls eisosome assembly and shape. J Cell Biol (2012) 0.95
Claudins: Gatekeepers of lung epithelial function. Semin Cell Dev Biol (2015) 0.94
Visualization and quantitative analysis of reconstituted tight junctions using localization microscopy. PLoS One (2012) 0.94
Impenetrable barriers or entry portals? The role of cell-cell adhesion during infection. J Cell Biol (2011) 0.93
IBD candidate genes and intestinal barrier regulation. Inflamm Bowel Dis (2014) 0.92
Hyaluronan fragments improve wound healing on in vitro cutaneous model through P2X7 purinoreceptor basal activation: role of molecular weight. PLoS One (2012) 0.92
"You Shall Not Pass"-tight junctions of the blood brain barrier. Front Neurosci (2014) 0.92
MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival. J Cell Biol (2014) 0.91
Dissociation and dispersion of claudin-3 from the tight junction could be one of the most sensitive indicators of reflux esophagitis in a rat model of the disease. J Gastroenterol (2011) 0.90
Claudins and tricellulin in fibrolamellar hepatocellular carcinoma. Virchows Arch (2011) 0.90
Methamphetamine-induced nitric oxide promotes vesicular transport in blood-brain barrier endothelial cells. Neuropharmacology (2012) 0.89
Holding Tight: Cell Junctions and Cancer Spread. Trends Cancer Res (2012) 0.89
Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion. Cell Cycle (2014) 0.88
Resistin increases monolayer permeability of human coronary artery endothelial cells. PLoS One (2013) 0.87
Statins Protect the Blood Brain Barrier Acutely after Experimental Intracerebral Hemorrhage. J Behav Brain Sci (2012) 0.87
Tight junctions: from simple barriers to multifunctional molecular gates. Nat Rev Mol Cell Biol (2016) 0.87
Connections matter--how viruses use cell–cell adhesion components. J Cell Sci (2015) 0.87
Regulation of blood-testis barrier (BTB) dynamics during spermatogenesis via the "Yin" and "Yang" effects of mammalian target of rapamycin complex 1 (mTORC1) and mTORC2. Int Rev Cell Mol Biol (2013) 0.86
The endodermis--development and differentiation of the plant's inner skin. Protoplasma (2011) 0.86
Protein-mediated interactions of pancreatic islet cells. Scientifica (Cairo) (2013) 0.85
Tbx2/3 is an essential mediator within the Brachyury gene network during Ciona notochord development. Development (2013) 0.84
Tight Junctions Go Viral! Viruses (2015) 0.84
Therapeutic applications of hydrogels in oral drug delivery. Expert Opin Drug Deliv (2014) 0.84
Secreted Frizzled-related protein 1 (sFRP1) regulates spermatid adhesion in the testis via dephosphorylation of focal adhesion kinase and the nectin-3 adhesion protein complex. FASEB J (2012) 0.84
Membrane trafficking in podocyte health and disease. Pediatr Nephrol (2012) 0.84
The distinct expression patterns of claudin-2, -6, and -11 between human gastric neoplasms and adjacent non-neoplastic tissues. Diagn Pathol (2013) 0.84
Identification of the amino acid region involved in the intercellular interaction between the β1 subunits of Na+/K+ -ATPase. J Cell Sci (2012) 0.83
A novel Peptide to treat oral mucositis blocks endothelial and epithelial cell apoptosis. Int J Radiat Oncol Biol Phys (2012) 0.82
Claudin family members exhibit unique temporal and spatial expression boundaries in the chick embryo. Tissue Barriers (2013) 0.82
Gene expression profiling of early-phase Sjögren's syndrome in C57BL/6.NOD-Aec1Aec2 mice identifies focal adhesion maturation associated with infiltrating leukocytes. Invest Ophthalmol Vis Sci (2011) 0.81
Valproic acid treatment inhibits hypoxia-inducible factor 1α accumulation and protects against burn-induced gut barrier dysfunction in a rodent model. PLoS One (2013) 0.81
microRNA-98 mediated microvascular hyperpermeability during burn shock phase via inhibiting FIH-1. Eur J Med Res (2015) 0.81
Mesothelium of the murine allantois exhibits distinct regional properties. J Morphol (2011) 0.80
Phosphatase regulation of intercellular junctions. Tissue Barriers (2013) 0.80
The reversible increase in tight junction permeability induced by capsaicin is mediated via cofilin-actin cytoskeletal dynamics and decreased level of occludin. PLoS One (2013) 0.80
Claudins and ki-67: potential markers to differentiate low- and high-grade transitional cell carcinomas of the urinary bladder. J Histochem Cytochem (2011) 0.79
Oxymatrine ameliorates L-arginine-induced acute pancreatitis in rats. Inflammation (2012) 0.79
Kin of IRRE-like Protein 2 Is a Phosphorylated Glycoprotein That Regulates Basal Insulin Secretion. J Biol Chem (2015) 0.79
Helicobacter pylori impedes acid-induced tightening of gastric epithelial junctions. Am J Physiol Gastrointest Liver Physiol (2013) 0.78
Reconstituted human upper airway epithelium as 3-d in vitro model for nasal polyposis. PLoS One (2014) 0.78
Molecular genetics of MARVELD2 and clinical phenotype in Pakistani and Slovak families segregating DFNB49 hearing loss. Hum Genet (2015) 0.78
Analysis of occludin trafficking, demonstrating continuous endocytosis, degradation, recycling and biosynthetic secretory trafficking. PLoS One (2014) 0.78
Endocytic Trafficking at the Mature Podocyte Slit Diaphragm. Front Pediatr (2017) 0.78
Regulation of immune cell infiltration into the CNS by regional neural inputs explained by the gate theory. Mediators Inflamm (2013) 0.78
Progressive Hearing Loss in Mice Carrying a Mutation in Usp53. J Neurosci (2015) 0.78
Tricellular Tight Junctions in the Inner Ear. Biomed Res Int (2016) 0.77
Beyond cell-cell adhesion: Emerging roles of the tight junction scaffold ZO-2. Tissue Barriers (2013) 0.77
Early Activation of MAPK p44/42 Is Partially Involved in DON-Induced Disruption of the Intestinal Barrier Function and Tight Junction Network. Toxins (Basel) (2016) 0.77
A high-calcium diet failed to rescue an osteopenia phenotype in claudin-18 knockout mice. Physiol Rep (2014) 0.77
TRP Channels Localize to Subdomains of the Apical Plasma Membrane in Human Fetal Retinal Pigment Epithelium. Invest Ophthalmol Vis Sci (2015) 0.77
High-mobility group box 1 impairs airway epithelial barrier function through the activation of the RAGE/ERK pathway. Int J Mol Med (2016) 0.77
Emerging multifunctional roles of Claudin tight junction proteins in bone. Endocrinology (2014) 0.77
Ouabain promotes partial epithelial to mesenchymal transition (EMT) changes in human autosomal dominant polycystic kidney disease (ADPKD) cells. Exp Cell Res (2017) 0.76
The Role of IL-17 and Related Cytokines in Inflammatory Autoimmune Diseases. Mediators Inflamm (2017) 0.76
Immunocytochemical localization of claudin-1 in the maturation ameloblasts of rat incisors. Front Physiol (2010) 0.76
Identification of Potential Biomarkers for Gut Barrier Failure in Broiler Chickens. Front Vet Sci (2015) 0.76
The phosphoinositide-binding protein TRAF4 modulates tight junction stability and migration of cancer cells. Tissue Barriers (2014) 0.76
The blood-brain barrier and methamphetamine: open sesame? Front Neurosci (2015) 0.76
HER2 activation results in β-catenin-dependent changes in pulmonary epithelial permeability. Am J Physiol Lung Cell Mol Physiol (2014) 0.76
Blockade of monocyte-endothelial trafficking by transduced Tat-superoxide dismutase protein. Int J Mol Med (2015) 0.75
Invited Commentary: Role of Estrogen Receptor-α in Regulating Claudin-6 Expression in Breast Cancer Cells. J Breast Cancer (2011) 0.75
Comprehensive functional analysis of Rab GTPases in Drosophila nephrocytes. Cell Tissue Res (2017) 0.75
Generation of a MDCK cell line with constitutive expression of the Enteropathogenic E. coli effector protein Map as an in vitro model of pathogenesis. Bioengineered (2015) 0.75
CCM1 and the second life of proteins in adhesion complexes. Cell Adh Migr (2014) 0.75
Indomethacin induces increase in gastric epithelial tight junction permeability via redistribution of occludin and activation of p38 MAPK in MKN-28 Cells. Tissue Barriers (2016) 0.75
The tumour suppressor DLC2 ensures mitotic fidelity by coordinating spindle positioning and cell-cell adhesion. Nat Commun (2014) 0.75
Tricellular Tight Junction Protein Tricellulin is targeted by the Enteropathogenic E. coli Effector EspG1 Leading to Epithelial Barrier Disruption. Infect Immun (2016) 0.75
Organ-Specific Differences in Endothelial Permeability-Regulating Molecular Responses in Mouse and Human Sepsis. Shock (2017) 0.75
Two types of functionally distinct fiber containing structural protein complexes are produced during infection of adenovirus serotype 5. PLoS One (2015) 0.75
Signalling to and from tight junctions. Nat Rev Mol Cell Biol (2003) 4.37
The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density. J Cell Biol (2003) 2.21
Tight junctions: molecular architecture and function. Int Rev Cytol (2006) 2.01
Identification of a tight junction-associated guanine nucleotide exchange factor that activates Rho and regulates paracellular permeability. J Cell Biol (2003) 2.00
Mammalian tight junctions in the regulation of epithelial differentiation and proliferation. Curr Opin Cell Biol (2005) 1.91
Tight junctions and the regulation of gene expression. Biochim Biophys Acta (2008) 1.83
Binding of GEF-H1 to the tight junction-associated adaptor cingulin results in inhibition of Rho signaling and G1/S phase transition. Dev Cell (2005) 1.79
Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis. Nat Cell Biol (2011) 1.75
Functional analysis of tight junctions. Methods (2003) 1.67
Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA. Mol Cell Biol (2006) 1.65
Tight junctions at a glance. J Cell Sci (2008) 1.46
The polarized expression of Na+,K+-ATPase in epithelia depends on the association between beta-subunits located in neighboring cells. Mol Biol Cell (2004) 1.40
Mutations in TOPORS cause autosomal dominant retinitis pigmentosa with perivascular retinal pigment epithelium atrophy. Am J Hum Genet (2007) 1.33
Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family. BMC Cell Biol (2009) 1.32
Epithelial cell adhesion and the regulation of gene expression. Trends Cell Biol (2003) 1.32
Rho signaling and tight junction functions. Physiology (Bethesda) (2010) 1.24
RalA interacts with ZONAB in a cell density-dependent manner and regulates its transcriptional activity. EMBO J (2004) 1.22
ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells. J Am Soc Nephrol (2010) 1.20
The RhoA activator GEF-H1/Lfc is a transforming growth factor-beta target gene and effector that regulates alpha-smooth muscle actin expression and cell migration. Mol Biol Cell (2010) 1.18
Matrix metalloproteinase-1 associates with intracellular organelles and confers resistance to lamin A/C degradation during apoptosis. Am J Pathol (2005) 1.14
Ouabain modulates epithelial cell tight junction. Proc Natl Acad Sci U S A (2010) 1.13
Myosin IXa regulates epithelial differentiation and its deficiency results in hydrocephalus. Mol Biol Cell (2009) 1.10
Functional interaction between the ZO-1-interacting transcription factor ZONAB/DbpA and the RNA processing factor symplekin. J Cell Sci (2006) 1.09
Junctional music that the nucleus hears: cell-cell contact signaling and the modulation of gene activity. Cold Spring Harb Perspect Biol (2009) 1.09
Regulation of renal epithelial tight junctions by the von Hippel-Lindau tumor suppressor gene involves occludin and claudin 1 and is independent of E-cadherin. Mol Biol Cell (2008) 1.03
Nuclear translocation of the Hsp70/Hsp90 organizing protein mSTI1 is regulated by cell cycle kinases. J Cell Sci (2004) 1.02
TOPORS, implicated in retinal degeneration, is a cilia-centrosomal protein. Hum Mol Genet (2010) 1.01
The heat-shock protein Apg-2 binds to the tight junction protein ZO-1 and regulates transcriptional activity of ZONAB. Mol Biol Cell (2006) 1.00
Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex. J Cell Biol (2012) 0.99
The Y-box factor ZONAB/DbpA associates with GEF-H1/Lfc and mediates Rho-stimulated transcription. EMBO Rep (2009) 0.99
The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice. PLoS One (2010) 0.99
Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasion. PLoS One (2012) 0.96
Holey barrier: claudins and the regulation of brain endothelial permeability. J Cell Biol (2003) 0.92
MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival. J Cell Biol (2014) 0.91
Phosphatidylethanol accumulation promotes intestinal hyperplasia by inducing ZONAB-mediated cell density increase in response to chronic ethanol exposure. Mol Cancer Res (2007) 0.90
Regulation of tight junction assembly and epithelial morphogenesis by the heat shock protein Apg-2. BMC Cell Biol (2007) 0.89
Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation. J Cell Biol (2013) 0.88
Lowe Syndrome protein OCRL1 supports maturation of polarized epithelial cells. PLoS One (2011) 0.86
Stress- and Rho-activated ZO-1-associated nucleic acid binding protein binding to p21 mRNA mediates stabilization, translation, and cell survival. Proc Natl Acad Sci U S A (2012) 0.83
Organization on the plasma membrane of the retinitis pigmentosa protein RP2: investigation of association with detergent-resistant membranes and polarized sorting. Biochem J (2003) 0.78
Cellular localization of Y-box binding protein 1 in brain tissue of rats, macaques, and humans. BMC Neurosci (2009) 0.76