Both low muscle mass and low fat are associated with higher all-cause mortality in hemodialysis patients.

PubWeight™: 1.55‹?› | Rank: Top 4%

🔗 View Article (PMC 3155769)

Published in Kidney Int on January 13, 2010

Authors

Cindy X Huang1, Hocine Tighiouart, Srinivasan Beddhu, Alfred K Cheung, Johanna T Dwyer, Garabed Eknoyan, Gerald J Beck, Andrew S Levey, Mark J Sarnak

Author Affiliations

1: Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts 02111, USA.

Articles citing this

Mid-arm muscle circumference and quality of life and survival in maintenance hemodialysis patients. Clin J Am Soc Nephrol (2010) 2.68

The obesity paradox and mortality associated with surrogates of body size and muscle mass in patients receiving hemodialysis. Mayo Clin Proc (2010) 2.55

Interdialytic creatinine change versus predialysis creatinine as indicators of nutritional status in maintenance hemodialysis. Nephrol Dial Transplant (2011) 1.69

Obesity paradox in end-stage kidney disease patients. Prog Cardiovasc Dis (2013) 1.52

Mortality prediction by surrogates of body composition: an examination of the obesity paradox in hemodialysis patients using composite ranking score analysis. Am J Epidemiol (2012) 1.49

Survival predictability of lean and fat mass in men and women undergoing maintenance hemodialysis. Am J Clin Nutr (2010) 1.29

Association between body composition and frailty among prevalent hemodialysis patients: a US Renal Data System special study. J Am Soc Nephrol (2013) 1.25

Evaluation of nutritional parameters of hemodialysis patients. Hippokratia (2012) 1.15

Mortality predictability of body size and muscle mass surrogates in Asian vs white and African American hemodialysis patients. Mayo Clin Proc (2013) 1.14

Protein-energy wasting and mortality in chronic kidney disease. Int J Environ Res Public Health (2011) 0.98

Targeting the myostatin signaling pathway to treat muscle wasting diseases. Curr Opin Support Palliat Care (2011) 0.96

Lean body mass predicts long-term survival in Chinese patients on peritoneal dialysis. PLoS One (2013) 0.95

Aerobic training during hemodialysis improves body composition, muscle function, physical performance, and quality of life in chronic kidney disease patients. J Phys Ther Sci (2015) 0.93

Lean Body Mass and Survival in Hemodialysis Patients and the Roles of Race and Ethnicity. J Ren Nutr (2015) 0.88

Anabolic exercise in haemodialysis patients: a randomised controlled pilot study. J Cachexia Sarcopenia Muscle (2014) 0.86

Body mass index and mortality risk in Asian peritoneal dialysis patients in Hong Kong-impact of diabetes and cardiovascular disease status. Perit Dial Int (2014) 0.85

Effect of oral anabolic steroid on muscle strength and muscle growth in hemodialysis patients. Clin J Am Soc Nephrol (2012) 0.84

Association of Adiponectin With Body Composition and Mortality in Hemodialysis Patients. Am J Kidney Dis (2015) 0.83

Combination with anthropometric measurements and MQSGA to assess nutritional status in Chinese hemodialysis population. Int J Med Sci (2013) 0.82

Creatinine index as a surrogate of lean body mass derived from urea Kt/V, pre-dialysis serum levels and anthropometric characteristics of haemodialysis patients. PLoS One (2014) 0.82

Comparison of bioimpedance and dual-energy x-ray absorptiometry for measurement of fat mass in hemodialysis patients. Nephron Clin Pract (2013) 0.82

Dietary restriction and exercise for diabetic patients with chronic kidney disease: a systematic review. PLoS One (2014) 0.79

Natural history of skeletal muscle mass changes in chronic kidney disease stage 4 and 5 patients: an observational study. PLoS One (2013) 0.79

Emerging role for regulated in development and DNA damage 1 (REDD1) in the regulation of skeletal muscle metabolism. Am J Physiol Endocrinol Metab (2016) 0.78

Ratio of Dietary n-6/n-3 Polyunsaturated Fatty Acids Independently Related to Muscle Mass Decline in Hemodialysis Patients. PLoS One (2015) 0.78

Examining the robustness of the obesity paradox in maintenance hemodialysis patients: a marginal structural model analysis. Nephrol Dial Transplant (2015) 0.77

Exercise as an Adjunct Therapy In Chronic Kidney Disease. Renal Nutr Forum (2015) 0.75

Early changes in body weight and blood pressure are associated with mortality in incident dialysis patients. Clin Kidney J (2016) 0.75

First year survival of patients on maintenance dialysis treatment in Poland. Nagoya J Med Sci (2015) 0.75

The relationship between left ventricular mass index and body composition in new-diagnosed hypertensive patients. Clin Hypertens (2015) 0.75

Sarcopenia and its individual criteria are associated, in part, with mortality among patients on hemodialysis. Kidney Int (2017) 0.75

A Simpler Creatinine Index Can Predict Long-Term Survival in Chinese Hemodialysis Patients. PLoS One (2016) 0.75

Abdominal Lean Muscle Is Associated with Lower Mortality among Kidney Waitlist Candidates. Clin Transplant (2017) 0.75

Renal osteodystrophy in the obesity era: Is metabolic syndrome relevant? PLoS One (2017) 0.75

Articles cited by this

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science (1993) 25.54

Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. Br J Nutr (1974) 16.83

Body-mass index and mortality in a prospective cohort of U.S. adults. N Engl J Med (1999) 16.57

Survival advantages of obesity in dialysis patients. Am J Clin Nutr (2005) 3.75

The importance of co-existent disease in the occurrence of postoperative complications and one-year recovery in patients undergoing total hip replacement. Comorbidity and outcomes after hip replacement. Med Care (1993) 3.19

The endocrine function of adipose tissue: an update. Clin Endocrinol (Oxf) (2006) 3.03

Body mass index and mortality in 'healthier' as compared with 'sicker' haemodialysis patients: results from the Dialysis Outcomes and Practice Patterns Study (DOPPS). Nephrol Dial Transplant (2001) 2.94

Atherosclerotic cardiovascular disease risks in chronic hemodialysis patients. Kidney Int (2000) 2.72

Associations of body fat and its changes over time with quality of life and prospective mortality in hemodialysis patients. Am J Clin Nutr (2006) 2.67

Body mass index, dialysis modality, and survival: analysis of the United States Renal Data System Dialysis Morbidity and Mortality Wave II Study. Kidney Int (2004) 2.47

Body weight-for-height relationships predict mortality in maintenance hemodialysis patients. Kidney Int (1999) 2.40

Cardiac diseases in maintenance hemodialysis patients: results of the HEMO Study. Kidney Int (2004) 2.38

Association of body size with outcomes among patients beginning dialysis. Am J Clin Nutr (2004) 2.37

Effects of body size and body composition on survival in hemodialysis patients. J Am Soc Nephrol (2003) 2.31

Body fat mass and lean mass as predictors of survival in hemodialysis patients. Kidney Int (2006) 2.04

Association of morbidity with markers of nutrition and inflammation in chronic hemodialysis patients: a prospective study. Kidney Int (1999) 1.89

Abdominal obesity and all-cause and cardiovascular mortality in end-stage renal disease. J Am Coll Cardiol (2009) 1.86

A central body fat distribution is related to renal function impairment, even in lean subjects. Am J Kidney Dis (2003) 1.82

Waist-to-hip ratio and body mass index as risk factors for cardiovascular events in CKD. Am J Kidney Dis (2008) 1.82

Simple nutritional indicators as independent predictors of mortality in hemodialysis patients. Am J Kidney Dis (1998) 1.78

Comparison of skinfold thicknesses and bioelectrical impedance analysis with dual-energy X-ray absorptiometry for the assessment of body fat in patients on long-term haemodialysis therapy. Nephrol Dial Transplant (2003) 1.76

HDL-inflammatory index correlates with poor outcome in hemodialysis patients. Kidney Int (2007) 1.75

Design and statistical issues of the hemodialysis (HEMO) study. Control Clin Trials (2000) 1.60

Obese sarcopenia in patients with end-stage renal disease is associated with inflammation and increased mortality. Am J Clin Nutr (2007) 1.55

Serum myeloperoxidase and mortality in maintenance hemodialysis patients. Am J Kidney Dis (2006) 1.44

Truncal fat mass as a contributor to inflammation in end-stage renal disease. Am J Clin Nutr (2004) 1.30

Adiposopathy: how do diet, exercise and weight loss drug therapies improve metabolic disease in overweight patients? Expert Rev Cardiovasc Ther (2006) 1.23

Inflammation and inverse associations of body mass index and serum creatinine with mortality in hemodialysis patients. J Ren Nutr (2007) 0.93

Assessment of body composition by dual energy X-ray absorptiometry, skinfold thickness and creatinine kinetics in chronic kidney disease patients. Nephrol Dial Transplant (2004) 0.91

Comparison of three methods for the determination of body fat in patients on long-term hemodialysis therapy. J Am Diet Assoc (2003) 0.90

Kt/V is the best dialysis dose parameter. Blood Purif (2000) 0.89

Body composition in hemodialysis patients measured by dual-energy X-ray absorptiometry. Am J Nephrol (1995) 0.89

The relationship between body fat distribution and renal damage in Chinese with obesity. Exp Clin Endocrinol Diabetes (2007) 0.81

Obesity and kidney transplantation. Contrib Nephrol (2006) 0.79

Articles by these authors

Prevalence of chronic kidney disease in the United States. JAMA (2007) 38.98

National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Ann Intern Med (2003) 23.33

Assessing kidney function--measured and estimated glomerular filtration rate. N Engl J Med (2006) 20.27

A Randomized Trial of Intensive versus Standard Blood-Pressure Control. N Engl J Med (2015) 19.14

Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis. Lancet (2010) 18.36

Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation (2003) 15.79

Cystatin C and the risk of death and cardiovascular events among elderly persons. N Engl J Med (2005) 15.30

Estimating GFR using serum cystatin C alone and in combination with serum creatinine: a pooled analysis of 3,418 individuals with CKD. Am J Kidney Dis (2008) 15.04

Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey. Am J Kidney Dis (2003) 15.00

Estimating glomerular filtration rate from serum creatinine and cystatin C. N Engl J Med (2012) 14.99

A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease. N Engl J Med (2009) 14.13

In-center hemodialysis six times per week versus three times per week. N Engl J Med (2010) 10.73

Effect of dialysis dose and membrane flux in maintenance hemodialysis. N Engl J Med (2002) 10.52

Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int (2005) 10.42

A randomized trial of aspirin to prevent colorectal adenomas. N Engl J Med (2003) 9.18

Recommendations for improving serum creatinine measurement: a report from the Laboratory Working Group of the National Kidney Disease Education Program. Clin Chem (2005) 8.93

Chronic kidney disease after nephrectomy in patients with renal cortical tumours: a retrospective cohort study. Lancet Oncol (2006) 8.61

Chronic kidney disease as a risk factor for cardiovascular disease and all-cause mortality: a pooled analysis of community-based studies. J Am Soc Nephrol (2004) 8.21

Cystatin C versus creatinine in determining risk based on kidney function. N Engl J Med (2013) 7.98

Folic acid for the prevention of colorectal adenomas: a randomized clinical trial. JAMA (2007) 7.93

Calibration of serum creatinine in the National Health and Nutrition Examination Surveys (NHANES) 1988-1994, 1999-2004. Am J Kidney Dis (2007) 7.86

Effect of clopidogrel on early failure of arteriovenous fistulas for hemodialysis: a randomized controlled trial. JAMA (2008) 7.50

Calibration and random variation of the serum creatinine assay as critical elements of using equations to estimate glomerular filtration rate. Am J Kidney Dis (2002) 7.03

Cystatin C and prognosis for cardiovascular and kidney outcomes in elderly persons without chronic kidney disease. Ann Intern Med (2006) 6.58

Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate. JAMA (2012) 6.26

Lower estimated GFR and higher albuminuria are associated with adverse kidney outcomes. A collaborative meta-analysis of general and high-risk population cohorts. Kidney Int (2011) 6.01

Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Hypertension (2003) 6.01

Evaluation of the modification of diet in renal disease study equation in a large diverse population. J Am Soc Nephrol (2007) 6.00

Factors other than glomerular filtration rate affect serum cystatin C levels. Kidney Int (2008) 5.90

Partial nephrectomy versus radical nephrectomy in patients with small renal tumors--is there a difference in mortality and cardiovascular outcomes? J Urol (2008) 5.70

Erythropoietic response and outcomes in kidney disease and type 2 diabetes. N Engl J Med (2010) 5.48

Progression of chronic kidney disease: the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: a patient-level meta-analysis. Ann Intern Med (2003) 5.47

Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts. Kidney Int (2011) 5.47

The effect of a lower target blood pressure on the progression of kidney disease: long-term follow-up of the modification of diet in renal disease study. Ann Intern Med (2005) 5.45

The timing of specialist evaluation in chronic kidney disease and mortality. Ann Intern Med (2002) 5.33

Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts. Kidney Int (2011) 5.25

Impact of creatinine calibration on performance of GFR estimating equations in a pooled individual patient database. Am J Kidney Dis (2007) 5.06

Kidney-Failure Risk Projection for the Living Kidney-Donor Candidate. N Engl J Med (2015) 5.03

Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without hypertension: a meta-analysis. Lancet (2012) 4.75

Dietary supplement use in the United States, 2003-2006. J Nutr (2010) 4.72

Total folate and folic acid intake from foods and dietary supplements in the United States: 2003-2006. Am J Clin Nutr (2009) 4.57

Comparison of drug dosing recommendations based on measured GFR and kidney function estimating equations. Am J Kidney Dis (2009) 4.30

The effects of frequent nocturnal home hemodialysis: the Frequent Hemodialysis Network Nocturnal Trial. Kidney Int (2011) 4.27

A predictive model for progression of chronic kidney disease to kidney failure. JAMA (2011) 4.22

The NHLBI lymphangioleiomyomatosis registry: characteristics of 230 patients at enrollment. Am J Respir Crit Care Med (2005) 4.15

Comparative performance of the CKD Epidemiology Collaboration (CKD-EPI) and the Modification of Diet in Renal Disease (MDRD) Study equations for estimating GFR levels above 60 mL/min/1.73 m2. Am J Kidney Dis (2010) 3.87

Estimation of total usual calcium and vitamin D intakes in the United States. J Nutr (2010) 3.86

Cystatin C identifies chronic kidney disease patients at higher risk for complications. J Am Soc Nephrol (2010) 3.85

Patient awareness of chronic kidney disease: trends and predictors. Arch Intern Med (2008) 3.72

Effect of dipyridamole plus aspirin on hemodialysis graft patency. N Engl J Med (2009) 3.69

Rapid kidney function decline and mortality risk in older adults. Arch Intern Med (2008) 3.54

Testing for chronic kidney disease: a position statement from the National Kidney Foundation. Am J Kidney Dis (2007) 3.53

FGF-23 associates with death, cardiovascular events, and initiation of chronic dialysis. J Am Soc Nephrol (2011) 3.52

Urinary N-acetyl-beta-(D)-glucosaminidase activity and kidney injury molecule-1 level are associated with adverse outcomes in acute renal failure. J Am Soc Nephrol (2007) 3.48

Level of kidney function as a risk factor for atherosclerotic cardiovascular outcomes in the community. J Am Coll Cardiol (2003) 3.48

Estimation of glomerular filtration rates before and after orthotopic liver transplantation: evaluation of current equations. Liver Transpl (2004) 3.46

Chronic kidney disease is common: what do we do next? Nephrol Dial Transplant (2008) 3.41

Effect of a very low-protein diet on outcomes: long-term follow-up of the Modification of Diet in Renal Disease (MDRD) Study. Am J Kidney Dis (2008) 3.34

Evolving importance of kidney disease: from subspecialty to global health burden. Lancet (2013) 3.30

Kidney function as a predictor of noncardiovascular mortality. J Am Soc Nephrol (2005) 3.28

Rapid decline of kidney function increases cardiovascular risk in the elderly. J Am Soc Nephrol (2009) 3.12

National Kidney Foundation's Kidney Disease Outcomes Quality Initiative clinical practice guidelines for chronic kidney disease in children and adolescents: evaluation, classification, and stratification. Pediatrics (2003) 3.10

Method of glomerular filtration rate estimation affects prediction of mortality risk. J Am Soc Nephrol (2009) 3.05

Measured GFR as a confirmatory test for estimated GFR. J Am Soc Nephrol (2009) 3.00

Expressing the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) cystatin C equations for estimating GFR with standardized serum cystatin C values. Am J Kidney Dis (2011) 2.98

A Trial of Calcium and Vitamin D for the Prevention of Colorectal Adenomas. N Engl J Med (2015) 2.88

25-hydroxyvitamin D levels inversely associate with risk for developing coronary artery calcification. J Am Soc Nephrol (2009) 2.87

Uric acid and long-term outcomes in CKD. Am J Kidney Dis (2009) 2.86

Imprecision of urinary iothalamate clearance as a gold-standard measure of GFR decreases the diagnostic accuracy of kidney function estimating equations. Am J Kidney Dis (2010) 2.83

Comparing the risk for death with peritoneal dialysis and hemodialysis in a national cohort of patients with chronic kidney disease. Ann Intern Med (2005) 2.82

Level of kidney function as a risk factor for cardiovascular outcomes in the elderly. Kidney Int (2003) 2.77

Hemodialysis vascular access dysfunction: a cellular and molecular viewpoint. J Am Soc Nephrol (2006) 2.74

Cystatin C as a risk factor for outcomes in chronic kidney disease. Ann Intern Med (2007) 2.71

Dietary supplement use is associated with higher intakes of minerals from food sources. Am J Clin Nutr (2011) 2.70