Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
The UHRF family: oncogenes that are drugable targets for cancer therapy in the near future?
|
Pharmacol Ther
|
2007
|
1.59
|
2
|
Vascular protection by dietary polyphenols.
|
Eur J Pharmacol
|
2004
|
1.57
|
3
|
Certain progestins prevent the enhancing effect of 17beta-estradiol on NO-mediated inhibition of platelet aggregation by endothelial cells.
|
Arterioscler Thromb Vasc Biol
|
2008
|
1.57
|
4
|
Cocoa procyanidins inhibit expression and activation of MMP-2 in vascular smooth muscle cells by direct inhibition of MEK and MT1-MMP activities.
|
Cardiovasc Res
|
2008
|
1.44
|
5
|
Antiangiogenic properties of natural polyphenols from red wine and green tea.
|
J Nutr Biochem
|
2005
|
1.14
|
6
|
Red wine polyphenol-induced, endothelium-dependent NO-mediated relaxation is due to the redox-sensitive PI3-kinase/Akt-dependent phosphorylation of endothelial NO-synthase in the isolated porcine coronary artery.
|
FASEB J
|
2004
|
1.12
|
7
|
UHRF1 recruits the histone acetyltransferase Tip60 and controls its expression and activity.
|
Biochem Biophys Res Commun
|
2009
|
1.10
|
8
|
Red wine polyphenols prevent angiotensin II-induced hypertension and endothelial dysfunction in rats: role of NADPH oxidase.
|
Cardiovasc Res
|
2006
|
1.07
|
9
|
Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer properties.
|
J Exp Clin Cancer Res
|
2011
|
1.07
|
10
|
Molecular mechanisms of the cardiovascular protective effects of polyphenols.
|
Br J Nutr
|
2012
|
1.02
|
11
|
Grape juice causes endothelium-dependent relaxation via a redox-sensitive Src- and Akt-dependent activation of eNOS.
|
Cardiovasc Res
|
2006
|
0.96
|
12
|
Losartan prevents portal hypertension-induced, redox-mediated endothelial dysfunction in the mesenteric artery in rats.
|
Gastroenterology
|
2009
|
0.93
|
13
|
Red wine polyphenols cause endothelium-dependent EDHF-mediated relaxations in porcine coronary arteries via a redox-sensitive mechanism.
|
Biochem Biophys Res Commun
|
2003
|
0.93
|
14
|
Induction of apoptosis by thymoquinone in lymphoblastic leukemia Jurkat cells is mediated by a p73-dependent pathway which targets the epigenetic integrator UHRF1.
|
Biochem Pharmacol
|
2009
|
0.92
|
15
|
Intake of grape-derived polyphenols reduces C26 tumor growth by inhibiting angiogenesis and inducing apoptosis.
|
FASEB J
|
2010
|
0.91
|
16
|
Red wine polyphenolic compounds inhibit vascular endothelial growth factor expression in vascular smooth muscle cells by preventing the activation of the p38 mitogen-activated protein kinase pathway.
|
Arterioscler Thromb Vasc Biol
|
2003
|
0.90
|
17
|
Red wine polyphenols induce EDHF-mediated relaxations in porcine coronary arteries through the redox-sensitive activation of the PI3-kinase/Akt pathway.
|
Br J Pharmacol
|
2004
|
0.90
|
18
|
Concerted regulation of cGMP and cAMP phosphodiesterases in early cardiac hypertrophy induced by angiotensin II.
|
PLoS One
|
2010
|
0.90
|
19
|
The EGCg-induced redox-sensitive activation of endothelial nitric oxide synthase and relaxation are critically dependent on hydroxyl moieties.
|
Biochem Biophys Res Commun
|
2010
|
0.88
|
20
|
Betanin--a food colorant with biological activity.
|
Mol Nutr Food Res
|
2014
|
0.88
|
21
|
eNOS activation induced by a polyphenol-rich grape skin extract in porcine coronary arteries.
|
J Vasc Res
|
2009
|
0.88
|
22
|
Red wine polyphenolic compounds strongly inhibit pro-matrix metalloproteinase-2 expression and its activation in response to thrombin via direct inhibition of membrane type 1-matrix metalloproteinase in vascular smooth muscle cells.
|
Circulation
|
2004
|
0.88
|
23
|
Epigallocatechin-3-gallate up-regulates tumor suppressor gene expression via a reactive oxygen species-dependent down-regulation of UHRF1.
|
Biochem Biophys Res Commun
|
2012
|
0.88
|
24
|
Catechins prevent vascular smooth muscle cell invasion by inhibiting MT1-MMP activity and MMP-2 expression.
|
Cardiovasc Res
|
2005
|
0.86
|
25
|
Procyanidin-rich fractions from Parkia biglobosa (Mimosaceae) leaves cause redox-sensitive endothelium-dependent relaxation involving NO and EDHF in porcine coronary artery.
|
J Ethnopharmacol
|
2010
|
0.86
|
26
|
Red wine polyphenols cause growth inhibition and apoptosis in acute lymphoblastic leukaemia cells by inducing a redox-sensitive up-regulation of p73 and down-regulation of UHRF1.
|
Eur J Cancer
|
2010
|
0.86
|
27
|
Crataegus special extract WS 1442 causes endothelium-dependent relaxation via a redox-sensitive Src- and Akt-dependent activation of endothelial NO synthase but not via activation of estrogen receptors.
|
J Cardiovasc Pharmacol
|
2009
|
0.86
|
28
|
Chronic intake of red wine polyphenols by young rats prevents aging-induced endothelial dysfunction and decline in physical performance: role of NADPH oxidase.
|
Biochem Biophys Res Commun
|
2010
|
0.85
|
29
|
Aronia melanocarpa juice, a rich source of polyphenols, induces endothelium-dependent relaxations in porcine coronary arteries via the redox-sensitive activation of endothelial nitric oxide synthase.
|
Nitric Oxide
|
2013
|
0.85
|
30
|
Catechin prevents endothelial dysfunction in the prediabetic stage of OLETF rats by reducing vascular NADPH oxidase activity and expression.
|
Atherosclerosis
|
2009
|
0.85
|
31
|
Expression of endothelial and inducible nitric oxide synthase in benign and malignant lesions of the breast and measurement of nitric oxide using electron paramagnetic resonance spectroscopy.
|
Cancer
|
2002
|
0.84
|
32
|
Endothelium-derived contracting factors mediate the Ang II-induced endothelial dysfunction in the rat aorta: preventive effect of red wine polyphenols.
|
Pflugers Arch
|
2009
|
0.84
|
33
|
The "Epigenetic Code Replication Machinery", ECREM: a promising drugable target of the epigenetic cell memory.
|
Curr Med Chem
|
2007
|
0.83
|
34
|
Red wine polyphenols improve an established aging-related endothelial dysfunction in the mesenteric artery of middle-aged rats: role of oxidative stress.
|
Biochem Biophys Res Commun
|
2012
|
0.82
|
35
|
Selective proapoptotic activity of polyphenols from red wine on teratocarcinoma cell, a model of cancer stem-like cell.
|
Invest New Drugs
|
2009
|
0.82
|
36
|
Aronia melanocarpa juice induces a redox-sensitive p73-related caspase 3-dependent apoptosis in human leukemia cells.
|
PLoS One
|
2012
|
0.82
|
37
|
Role of S-nitrosation of cysteine residues in long-lasting inhibitory effect of nitric oxide on arterial tone.
|
Mol Pharmacol
|
2003
|
0.81
|
38
|
An ethanolic extract of Lindera obtusiloba stems, YJP-14, improves endothelial dysfunction, metabolic parameters and physical performance in diabetic db/db mice.
|
PLoS One
|
2013
|
0.81
|
39
|
Role of gender and estrogen receptors in the rat aorta endothelium-dependent relaxation to red wine polyphenols.
|
Vascul Pharmacol
|
2009
|
0.81
|
40
|
Angiotensin II induces the vascular expression of VEGF and MMP-2 in vivo: preventive effect of red wine polyphenols.
|
J Vasc Res
|
2008
|
0.81
|
41
|
Anti-neoplastic agent thymoquinone induces degradation of α and β tubulin proteins in human cancer cells without affecting their level in normal human fibroblasts.
|
Invest New Drugs
|
2011
|
0.80
|
42
|
Progestins overcome inhibition of platelet aggregation by endothelial cells by down-regulating endothelial NO synthase via glucocorticoid receptors.
|
FASEB J
|
2006
|
0.80
|
43
|
Grape-derived polyphenols improve aging-related endothelial dysfunction in rat mesenteric artery: role of oxidative stress and the angiotensin system.
|
PLoS One
|
2012
|
0.80
|
44
|
Close relationship between the platelet activation marker CD62 and the granular release of platelet-derived growth factor.
|
J Pharmacol Exp Ther
|
2002
|
0.79
|
45
|
The red wine extract-induced activation of endothelial nitric oxide synthase is mediated by a great variety of polyphenolic compounds.
|
Mol Nutr Food Res
|
2010
|
0.79
|
46
|
Grape-Derived Polyphenols Prevent Doxorubicin-Induced Blunted EDH-Mediated Relaxations in the Rat Mesenteric Artery: Role of ROS and Angiotensin II.
|
Evid Based Complement Alternat Med
|
2013
|
0.78
|
47
|
Red wine polyphenols prevent acceleration of neovascularization by angiotensin II in the ischemic rat hindlimb.
|
J Pharmacol Exp Ther
|
2009
|
0.78
|
48
|
Targeted and persistent effects of NO mediated by S-nitrosation of tissue thiols in arteries with endothelial dysfunction.
|
Nitric Oxide
|
2007
|
0.78
|
49
|
Vascular effects of ovariectomy and chronic oestrogen treatment in rats: controversy or experimental protocol diversity?
|
Br J Pharmacol
|
2005
|
0.78
|
50
|
Formation of releasable NO stores by S-nitrosoglutathione in arteries exhibiting tolerance to glyceryl-trinitrate.
|
Eur J Pharmacol
|
2005
|
0.78
|
51
|
Redox-sensitive up-regulation of eNOS by purple grape juice in endothelial cells: role of PI3-kinase/Akt, p38 MAPK, JNK, FoxO1 and FoxO3a.
|
PLoS One
|
2013
|
0.77
|
52
|
Role of AMP-activated Protein Kinase in NO- and EDHF-mediated Endothelium-dependent Relaxations to Red Wine Polyphenols.
|
Indian J Physiol Pharmacol
|
2016
|
0.76
|
53
|
Great heterogeneity of commercial fruit juices to induce endothelium-dependent relaxations in isolated porcine coronary arteries: role of the phenolic content and composition.
|
J Med Food
|
2015
|
0.76
|
54
|
An ethanolic extract of Lindera obtusiloba stems causes NO-mediated endothelium-dependent relaxations in rat aortic rings and prevents angiotensin II-induced hypertension and endothelial dysfunction in rats.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2011
|
0.76
|
55
|
Hydroxylation of (-)-epigallocatechin-3-O-gallate at 3'', but not 4'', is essential for the PI3-kinase/Akt-dependent phosphorylation of endothelial NO synthase in endothelial cells and relaxation of coronary artery rings.
|
Food Funct
|
2013
|
0.76
|
56
|
Mechanisms underlying the endothelium-dependent vasodilatory effect of an aqueous extract of Elaeis Guineensis Jacq. (Arecaceae) in porcine coronary artery rings.
|
Afr J Tradit Complement Altern Med
|
2009
|
0.75
|
57
|
Fruit juice-induced endothelium-dependent relaxations in isolated porcine coronary arteries: evaluation of different fruit juices and purees and optimization of a red fruit juice blend.
|
Food Funct
|
2011
|
0.75
|
58
|
Natural product extract of Dicksonia sellowiana induces endothelium-dependent relaxations by a redox-sensitive Src- and Akt-dependent activation of eNOS in porcine coronary arteries.
|
J Vasc Res
|
2012
|
0.75
|
59
|
The Effect of Quercus salicina Leaf Extracts on Vascular Endothelial Function: Role of Nitric Oxide.
|
J Nanosci Nanotechnol
|
2016
|
0.75
|
60
|
Do iodinated nano-emulsions designed for preclinical vascular imaging alter the vascular reactivity in rat aorta?
|
Int J Pharm
|
2013
|
0.75
|
61
|
Potential of Food and Natural Products to Promote Endothelial and Vascular Health.
|
J Cardiovasc Pharmacol
|
2016
|
0.75
|