Multi-site optical excitation using ChR2 and micro-LED array.

PubWeight™: 1.52‹?› | Rank: Top 4%

🔗 View Article (PMID 20075504)

Published in J Neural Eng on January 14, 2010

Authors

Nir Grossman1, Vincent Poher, Matthew S Grubb, Gordon T Kennedy, Konstantin Nikolic, Brian McGovern, Rolando Berlinguer Palmini, Zheng Gong, Emmanuel M Drakakis, Mark A A Neil, Martin D Dawson, Juan Burrone, Patrick Degenaar

Author Affiliations

1: Institute of Biomedical Engineering, Imperial College, London, UK. Devision of Neuroscience, Imperial College, London, UK. nir.grossman@imperial.ac.uk

Articles citing this

Optogenetic investigation of neural circuits underlying brain disease in animal models. Nat Rev Neurosci (2012) 4.35

Remote control of neuronal signaling. Pharmacol Rev (2011) 2.66

Scanless two-photon excitation of channelrhodopsin-2. Nat Methods (2010) 2.60

Challenges and opportunities for next-generation intracortically based neural prostheses. IEEE Trans Biomed Eng (2011) 1.78

Diode probes for spatiotemporal optical control of multiple neurons in freely moving animals. J Neurophysiol (2012) 1.77

Closed-loop and activity-guided optogenetic control. Neuron (2015) 1.42

Formation and optogenetic control of engineered 3D skeletal muscle bioactuators. Lab Chip (2012) 1.28

Holographic optogenetic stimulation of patterned neuronal activity for vision restoration. Nat Commun (2013) 1.12

Endogenous voltage gradients as mediators of cell-cell communication: strategies for investigating bioelectrical signals during pattern formation. Cell Tissue Res (2012) 1.09

Multipoint-emitting optical fibers for spatially addressable in vivo optogenetics. Neuron (2014) 1.06

A 3D glass optrode array for optical neural stimulation. Biomed Opt Express (2012) 0.99

A multispectral optical illumination system with precise spatiotemporal control for the manipulation of optogenetic reagents. Nat Protoc (2012) 0.97

Vector platforms for gene therapy of inherited retinopathies. Prog Retin Eye Res (2014) 0.94

Design, fabrication, and packaging of an integrated, wirelessly-powered optrode array for optogenetics application. Front Syst Neurosci (2015) 0.91

Optogenetic activation of neocortical neurons in vivo with a sapphire-based micro-scale LED probe. Front Neural Circuits (2015) 0.89

The spatial pattern of light determines the kinetics and modulates backpropagation of optogenetic action potentials. J Comput Neurosci (2012) 0.89

Optrodes for combined optogenetics and electrophysiology in live animals. Neurophotonics (2015) 0.89

Emerging gene therapies for retinal degenerations. J Neurosci (2012) 0.87

Arrays of microscopic organic LEDs for high-resolution optogenetics. Sci Adv (2016) 0.86

High-brightness organic light-emitting diodes for optogenetic control of Drosophila locomotor behaviour. Sci Rep (2016) 0.86

Computer-generated holography enhances voltage dye fluorescence discrimination in adjacent neuronal structures. Neurophotonics (2015) 0.86

Delivery of continuously-varying stimuli using channelrhodopsin-2. Front Neural Circuits (2013) 0.84

Using affordable LED arrays for photo-stimulation of neurons. J Vis Exp (2011) 0.83

Optogenetics, physiology, and emotions. Front Behav Neurosci (2013) 0.83

Blockade of pathological retinal ganglion cell hyperactivity improves optogenetically evoked light responses in rd1 mice. Front Cell Neurosci (2015) 0.83

Optogenetic tools for modulating and probing the epileptic network. Epilepsy Res (2015) 0.83

OptogenSIM: a 3D Monte Carlo simulation platform for light delivery design in optogenetics. Biomed Opt Express (2015) 0.83

Optogenetic approaches to retinal prosthesis. Vis Neurosci (2014) 0.81

Evolution of optogenetic microdevices. Neurophotonics (2015) 0.79

Fully implantable, battery-free wireless optoelectronic devices for spinal optogenetics. Pain (2017) 0.79

A system for optically controlling neural circuits with very high spatial and temporal resolution. Proc IEEE Int Symp Bioinformatics Bioeng (2013) 0.78

Prospects for Optogenetic Augmentation of Brain Function. Front Syst Neurosci (2015) 0.78

Developing an Outcome Measure With High Luminance for Optogenetics Treatment of Severe Retinal Degenerations and for Gene Therapy of Cone Diseases. Invest Ophthalmol Vis Sci (2016) 0.77

Optical triggered seizures using a caged 4-Aminopyridine. Front Neurosci (2015) 0.77

Optogenetic spatial and temporal control of cortical circuits on a columnar scale. J Neurophysiol (2015) 0.76

Arrays of microLEDs and astrocytes: biological amplifiers to optogenetically modulate neuronal networks reducing light requirement. PLoS One (2014) 0.76

Optical Techniques in Optogenetics. J Mod Opt (2015) 0.75

A targeted illumination optical fiber probe for high resolution fluorescence imaging and optical switching. Sci Rep (2017) 0.75

An integrated multi-electrode-optrode array for in vitro optogenetics. Sci Rep (2016) 0.75

Fabrication and analysis of microfiber array platform for optogenetics with cellular resolution. Biomed Opt Express (2016) 0.75

Illuminating the Undergraduate Behavioral Neuroscience Laboratory: A Guide for the in vivo Application of Optogenetics in Mammalian Model Organisms. J Undergrad Neurosci Educ (2016) 0.75

Articles by these authors

Adult neurogenesis and functional plasticity in neuronal circuits. Nat Rev Neurosci (2006) 5.89

Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability. Nature (2010) 3.05

Structurally distinct membrane nanotubes between human macrophages support long-distance vesicular traffic or surfing of bacteria. J Immunol (2006) 2.65

Adaptive aberration correction in a confocal microscope. Proc Natl Acad Sci U S A (2002) 2.32

A resting pool of vesicles is responsible for spontaneous vesicle fusion at the synapse. Nat Neurosci (2009) 2.09

Activity-dependent regulation of inhibitory synaptic transmission in hippocampal neurons. Nat Neurosci (2006) 1.94

Synaptic vesicle recycling studied in transgenic mice expressing synaptopHluorin. Proc Natl Acad Sci U S A (2005) 1.93

Photocycles of channelrhodopsin-2. Photochem Photobiol (2009) 1.76

Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy. PLoS Biol (2011) 1.70

Dynamics of subsynaptic vesicles and surface microclusters at the immunological synapse. Sci Signal (2010) 1.69

Dynamic structured-light measurement for wheel diameter based on the cycloid constraint. Appl Opt (2016) 1.53

Microtextured surfaces for deep-brain stimulation electrodes: a biologically inspired design to reduce lead migration. World Neurosurg (2011) 1.43

Microclusters of inhibitory killer immunoglobulin-like receptor signaling at natural killer cell immunological synapses. J Cell Biol (2006) 1.42

Synaptic activity and activity-dependent competition regulates axon arbor maturation, growth arrest, and territory in the retinotectal projection. J Neurosci (2010) 1.41

Critical population density triggers rapid formation of vast oceanic fish shoals. Science (2009) 1.37

Optical control of muscle function by transplantation of stem cell-derived motor neurons in mice. Science (2014) 1.27

Stimulated emission depletion microscopy with a supercontinuum source and fluorescence lifetime imaging. Opt Lett (2008) 1.25

Multiplexed FRET to image multiple signaling events in live cells. Biophys J (2008) 1.23

Continuous-flow polymerase chain reaction of single-copy DNA in microfluidic microdroplets. Anal Chem (2009) 1.19

Optobionic vision--a new genetically enhanced light on retinal prosthesis. J Neural Eng (2009) 1.18

Building and maintaining the axon initial segment. Curr Opin Neurobiol (2010) 1.18

Turning astrocytes from the rostral migratory stream into neurons: a role for the olfactory sensory organ. J Neurosci (2008) 1.17

Fluorescence lifetime imaging provides enhanced contrast when imaging the phase-sensitive dye di-4-ANEPPDHQ in model membranes and live cells. Biophys J (2006) 1.17

Quantitative 3D mapping of fluidic temperatures within microchannel networks using fluorescence lifetime imaging. Anal Chem (2006) 1.15

High-speed high-resolution imaging of intercellular immune synapses using optical tweezers. Biophys J (2008) 1.14

Wide-field fluorescence lifetime imaging of cancer. Biomed Opt Express (2010) 1.13

Fluorescence imaging of two-photon linear dichroism: cholesterol depletion disrupts molecular orientation in cell membranes. Biophys J (2004) 1.11

Channelrhodopsin-2 localised to the axon initial segment. PLoS One (2010) 1.10

Multiphoton multispectral fluorescence lifetime tomography for the evaluation of basal cell carcinomas. PLoS One (2012) 1.10

Plasmin potentiates synaptic N-methyl-D-aspartate receptor function in hippocampal neurons through activation of protease-activated receptor-1. J Biol Chem (2008) 1.09

A fluorescence lifetime imaging scanning confocal endomicroscope. J Biophotonics (2010) 1.09

Modeling study of the light stimulation of a neuron cell with channelrhodopsin-2 mutants. IEEE Trans Biomed Eng (2011) 1.09

FLIM FRET technology for drug discovery: automated multiwell-plate high-content analysis, multiplexed readouts and application in situ. Chemphyschem (2011) 1.08

A first step towards practical single cell proteomics: a microfluidic antibody capture chip with TIRF detection. Lab Chip (2011) 1.08

High speed unsupervised fluorescence lifetime imaging confocal multiwell plate reader for high content analysis. J Biophotonics (2008) 1.07

Fluorescence lifetime imaging by using time-gated data acquisition. Appl Opt (2007) 1.06

High plasma membrane lipid order imaged at the immunological synapse periphery in live T cells. Mol Membr Biol (2010) 1.04

Fluorescence lifetime optical projection tomography. J Biophotonics (2008) 1.02

Two cases of multinodular and vacuolating neuronal tumour. Acta Neuropathol Commun (2014) 1.01

A compact, multidimensional spectrofluorometer exploiting supercontinuum generation. J Biophotonics (2008) 1.01

Calcineurin signaling mediates activity-dependent relocation of the axon initial segment. J Neurosci (2013) 1.01

Curcumin protects microglia and primary rat cortical neurons against HIV-1 gp120-mediated inflammation and apoptosis. PLoS One (2013) 1.01

Neuronal activity drives matching of pre- and postsynaptic function during synapse maturation. Nat Neurosci (2011) 0.99

New modal wave-front sensor: application to adaptive confocal fluorescence microscopy and two-photon excitation fluorescence microscopy. J Opt Soc Am A Opt Image Sci Vis (2002) 0.97

Excitation-resolved hyperspectral fluorescence lifetime imaging using a UV-extended supercontinuum source. Opt Lett (2007) 0.97

Automated fluorescence lifetime imaging plate reader and its application to Förster resonant energy transfer readout of Gag protein aggregation. J Biophotonics (2012) 0.96

Live cell linear dichroism imaging reveals extensive membrane ruffling within the docking structure of natural killer cell immune synapses. Biophys J (2009) 0.96

Slow-light in a vertical-cavity semiconductor optical amplifier. Opt Express (2006) 0.95

A simulation study of the combined thermoelectric extracellular stimulation of the sciatic nerve of the Xenopus laevis: the localized transient heat block. IEEE Trans Biomed Eng (2012) 0.95

Modeling and engineering aspects of channelrhodopsin2 system for neural photostimulation. Conf Proc IEEE Eng Med Biol Soc (2006) 0.94

Thermal and optical characterization of micro-LED probes for in vivo optogenetic neural stimulation. Opt Lett (2013) 0.94

Functional imaging in the zebrafish retinotectal system using RGECO. Front Neural Circuits (2013) 0.93

Tunable single-mode fiber-VCSEL using an intracavity polymer microlens. Opt Lett (2007) 0.93

Cadmium is a potent inhibitor of PPM phosphatases and targets the M1 binding site. Sci Rep (2013) 0.92

Colloidal quantum dot random laser. Opt Express (2011) 0.92

Enhanced anammox consortium activity for nitrogen removal: impacts of static magnetic field. J Biotechnol (2008) 0.91

Laser-pumped endoscopic illumination source. Conf Proc IEEE Eng Med Biol Soc (2008) 0.91

Independent vesicle pools underlie different modes of release during neuronal development. J Neurosci (2012) 0.90

The spatial pattern of light determines the kinetics and modulates backpropagation of optogenetic action potentials. J Comput Neurosci (2012) 0.89

Intelligent bioprocessing for haemotopoietic cell cultures using monitoring and design of experiments. Biotechnol Adv (2007) 0.88

Application of ultrafast gold luminescence to measuring the instrument response function for multispectral multiphoton fluorescence lifetime imaging. Opt Express (2011) 0.88

Membrane environment exerts an important influence on rac-mediated activation of phospholipase Cγ2. Mol Cell Biol (2011) 0.87

Optical techniques for imaging membrane lipid microdomains in living cells. Semin Cell Dev Biol (2007) 0.87

Miniaturized optoelectronic tweezers controlled by GaN micro-pixel light emitting diode arrays. Opt Express (2011) 0.86

Self-oligomerization is essential for enhanced immunological activities of soluble recombinant calreticulin. PLoS One (2013) 0.86

Adaptive phase compensation for ultracompact laser scanning endomicroscopy. Opt Lett (2011) 0.86

Remote ischemic preconditioning protects neurocognitive function of rats following cerebral hypoperfusion. Med Sci Monit (2011) 0.86

Para-Hisian entrainment: a novel pacing maneuver to differentiate orthodromic atrioventricular reentrant tachycardia from atrioventricular nodal reentrant tachycardia. J Cardiovasc Electrophysiol (2003) 0.86

Quantification of cellular autofluorescence of human skin using multiphoton tomography and fluorescence lifetime imaging in two spectral detection channels. Biomed Opt Express (2011) 0.85

Complete genome sequences of newcastle disease virus strains isolated from three different poultry species in china. Genome Announc (2013) 0.85

Fluorescence-lifetime imaging of DNA-dye interactions within continuous-flow microfluidic systems. Angew Chem Int Ed Engl (2007) 0.84

A stochastic model of the single photon response in Drosophila photoreceptors. Integr Biol (Camb) (2010) 0.84

A sub-mW fully-integrated pulse oximeter front-end. IEEE Trans Biomed Circuits Syst (2013) 0.83

Systematic computation of nonlinear cellular and molecular dynamics with low-power CytoMimetic circuits: a simulation study. PLoS One (2013) 0.83

Assessment of the positive effect of salinity on the nitrogen removal performance and microbial composition during the start-up of CANON process. Appl Microbiol Biotechnol (2008) 0.83

PB/PANI-modified electrode used as a novel oxygen reduction cathode in microbial fuel cell. Biosens Bioelectron (2010) 0.82

Analysis of DNA binding and nucleotide flipping kinetics using two-color two-photon fluorescence lifetime imaging microscopy. Anal Chem (2014) 0.82

Metal-dependent protein phosphatase 1A functions as an extracellular signal-regulated kinase phosphatase. FEBS J (2013) 0.81

In vivo measurements of diffuse reflectance and time-resolved autofluorescence emission spectra of basal cell carcinomas. J Biophotonics (2012) 0.81

Computational models of optogenetic tools for controlling neural circuits with light. Conf Proc IEEE Eng Med Biol Soc (2013) 0.81

Prophylactic Lamivudine to Improve the Outcome of Breast Cancer Patients With HBsAg Positive During Chemotherapy: A Meta-Analysis. Hepat Mon (2013) 0.81

Enzyme-linked sensitive fluorometric imaging of glutamate release from cerebral neurons of chick embryos. J Biochem (2003) 0.81

A processing platform for optoelectronic/optogenetic retinal prosthesis. IEEE Trans Biomed Eng (2011) 0.81

3-D stimulated emission depletion microscopy with programmable aberration correction. J Biophotonics (2013) 0.81

Improved sectioning in a slit scanning confocal microscope. Opt Lett (2008) 0.80

Non cross-bridge stiffness in skeletal muscle fibres at rest and during activity. Adv Exp Med Biol (2005) 0.80

Application of anaerobic ammonium-oxidizing consortium to achieve completely autotrophic ammonium and sulfate removal. Bioresour Technol (2008) 0.80

Optoelectronic tweezers system for single cell manipulation and fluorescence imaging of live immune cells. Opt Express (2014) 0.80

Dynamic axial-position control of a laser-trapped particle by wave-front modification. Opt Lett (2003) 0.80

A microfluidic platform for probing single cell plasma membranes using optically trapped Smart Droplet Microtools (SDMs). Lab Chip (2009) 0.80

A CMOS Time-Resolved Fluorescence Lifetime Analysis Micro-System. Sensors (Basel) (2009) 0.79