| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Investigational NMDA receptor modulators for depression.
|
Expert Opin Investig Drugs
|
2011
|
1.45
|
|
2
|
Mood disorders: regulation by metabotropic glutamate receptors.
|
Biochem Pharmacol
|
2007
|
1.22
|
|
3
|
New drug targets in depression: inflammatory, cell-mediated immune, oxidative and nitrosative stress, mitochondrial, antioxidant, and neuroprogressive pathways. And new drug candidates--Nrf2 activators and GSK-3 inhibitors.
|
Inflammopharmacology
|
2012
|
1.06
|
|
4
|
Zinc supplementation augments efficacy of imipramine in treatment resistant patients: a double blind, placebo-controlled study.
|
J Affect Disord
|
2009
|
1.05
|
|
5
|
NMDA/glutamate mechanism of antidepressant-like action of magnesium in forced swim test in mice.
|
Pharmacol Biochem Behav
|
2007
|
1.01
|
|
6
|
Lack of persistent effects of ketamine in rodent models of depression.
|
Psychopharmacology (Berl)
|
2008
|
1.01
|
|
7
|
GABAergic hypotheses of anxiety and depression: focus on GABA-B receptors.
|
Drugs Today (Barc)
|
2005
|
0.99
|
|
8
|
Anxiolytic-like effects of MTEP, a potent and selective mGlu5 receptor agonist does not involve GABA(A) signaling.
|
Neuropharmacology
|
2004
|
0.99
|
|
9
|
The efficacy of zinc supplementation in depression: systematic review of randomised controlled trials.
|
J Affect Disord
|
2011
|
0.96
|
|
10
|
The involvement of serotonergic system in the antidepressant effect of zinc in the forced swim test.
|
Prog Neuropsychopharmacol Biol Psychiatry
|
2008
|
0.96
|
|
11
|
Antidepressant-like activity of zinc: further behavioral and molecular evidence.
|
J Neural Transm (Vienna)
|
2008
|
0.94
|
|
12
|
(Neuro)inflammation and neuroprogression as new pathways and drug targets in depression: from antioxidants to kinase inhibitors.
|
Prog Neuropsychopharmacol Biol Psychiatry
|
2011
|
0.92
|
|
13
|
Characterization of the antinociceptive actions of bicifadine in models of acute, persistent, and chronic pain.
|
J Pharmacol Exp Ther
|
2007
|
0.92
|
|
14
|
Serum zinc level in depressed patients during zinc supplementation of imipramine treatment.
|
J Affect Disord
|
2010
|
0.92
|
|
15
|
Antidepressant activity of zinc and magnesium in view of the current hypotheses of antidepressant action.
|
Pharmacol Rep
|
2008
|
0.92
|
|
16
|
A complex interaction between glycine/NMDA receptors and serotonergic/noradrenergic antidepressants in the forced swim test in mice.
|
J Neural Transm (Vienna)
|
2011
|
0.91
|
|
17
|
Antidepressant and antipsychotic activity of new quinoline- and isoquinoline-sulfonamide analogs of aripiprazole targeting serotonin 5-HT₁A/5-HT₂A/5-HT₇ and dopamine D₂/D₃ receptors.
|
Eur J Med Chem
|
2012
|
0.90
|
|
18
|
Antepartum/postpartum depressive symptoms and serum zinc and magnesium levels.
|
Pharmacol Rep
|
2006
|
0.90
|
|
19
|
The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors.
|
J Pharmacol Exp Ther
|
2006
|
0.89
|
|
20
|
The role of zinc in neurodegenerative inflammatory pathways in depression.
|
Prog Neuropsychopharmacol Biol Psychiatry
|
2010
|
0.89
|
|
21
|
Immobility stress induces depression-like behavior in the forced swim test in mice: effect of magnesium and imipramine.
|
Pharmacol Rep
|
2006
|
0.88
|
|
22
|
Effects of GABAB receptor ligands in rodent tests of anxiety-like behavior.
|
Pharmacol Rep
|
2008
|
0.86
|
|
23
|
Identification of novel serotonin transporter compounds by virtual screening.
|
J Chem Inf Model
|
2014
|
0.86
|
|
24
|
Interaction of zinc with antidepressants in the forced swimming test in mice.
|
Pol J Pharmacol
|
2003
|
0.85
|
|
25
|
Time course of zinc deprivation-induced alterations of mice behavior in the forced swim test.
|
Pharmacol Rep
|
2012
|
0.85
|
|
26
|
Synthesis and pharmacological evaluation of new 5-(cyclo)alkyl-5-phenyl- and 5-spiroimidazolidine-2,4-dione derivatives. Novel 5-HT1A receptor agonist with potential antidepressant and anxiolytic activity.
|
Eur J Med Chem
|
2009
|
0.85
|
|
27
|
Antidepressant- and anxiolytic-like activity of magnesium in mice.
|
Pharmacol Biochem Behav
|
2004
|
0.85
|
|
28
|
NMDA/glutamate mechanism of magnesium-induced anxiolytic-like behavior in mice.
|
Pharmacol Rep
|
2008
|
0.85
|
|
29
|
Zinc deficiency induces behavioral alterations in the tail suspension test in mice. Effect of antidepressants.
|
Pharmacol Rep
|
2012
|
0.84
|
|
30
|
NMDA antagonists under investigation for the treatment of major depressive disorder.
|
Expert Opin Investig Drugs
|
2014
|
0.84
|
|
31
|
Pharmacological profile of the "triple" monoamine neurotransmitter uptake inhibitor, DOV 102,677.
|
Cell Mol Neurobiol
|
2006
|
0.84
|
|
32
|
GPR39 up-regulation after selective antidepressants.
|
Neurochem Int
|
2013
|
0.84
|
|
33
|
Enhancement of antidepressant-like activity by joint administration of imipramine and magnesium in the forced swim test: Behavioral and pharmacokinetic studies in mice.
|
Pharmacol Biochem Behav
|
2005
|
0.84
|
|
34
|
Zinc-induced adaptive changes in NMDA/glutamatergic and serotonergic receptors.
|
Pharmacol Rep
|
2010
|
0.83
|
|
35
|
Magnesium in depression.
|
Pharmacol Rep
|
2013
|
0.83
|
|
36
|
The involvement of NMDA and AMPA receptors in the mechanism of antidepressant-like action of zinc in the forced swim test.
|
Amino Acids
|
2009
|
0.82
|
|
37
|
Oxidative stress markers in affective disorders.
|
Pharmacol Rep
|
2013
|
0.82
|
|
38
|
NMDA but not AMPA glutamatergic receptors are involved in the antidepressant-like activity of MTEP during the forced swim test in mice.
|
Pharmacol Rep
|
2011
|
0.82
|
|
39
|
Chronic treatment with zinc and antidepressants induces enhancement of presynaptic/extracellular zinc concentration in the rat prefrontal cortex.
|
Amino Acids
|
2010
|
0.82
|
|
40
|
The role of the GPR39 receptor in zinc deficient-animal model of depression.
|
Behav Brain Res
|
2012
|
0.82
|
|
41
|
Zinc, magnesium and NMDA receptor alterations in the hippocampus of suicide victims.
|
J Affect Disord
|
2013
|
0.82
|
|
42
|
D-serine, a selective glycine/N-methyl-D-aspartate receptor agonist, antagonizes the antidepressant-like effects of magnesium and zinc in mice.
|
Pharmacol Rep
|
2009
|
0.81
|
|
43
|
Effect of MPEP treatment on brain-derived neurotrophic factor gene expression.
|
Pharmacol Rep
|
2006
|
0.81
|
|
44
|
Pregabalin for the treatment of social anxiety disorder.
|
Expert Opin Investig Drugs
|
2014
|
0.80
|
|
45
|
Chronic unpredictable stress-induced reduction in the hippocampal brain-derived neurotrophic factor (BDNF) gene expression is antagonized by zinc treatment.
|
Pharmacol Rep
|
2011
|
0.80
|
|
46
|
Effects of ifenprodil on the antidepressant-like activity of NMDA ligands in the forced swim test in mice.
|
Prog Neuropsychopharmacol Biol Psychiatry
|
2013
|
0.80
|
|
47
|
Biological consequences of zinc deficiency in the pathomechanisms of selected diseases.
|
J Biol Inorg Chem
|
2014
|
0.79
|
|
48
|
Activation of the NMDA/glutamate receptor complex antagonizes the NMDA antagonist-induced antidepressant-like effects in the forced swim test.
|
Pharmacol Rep
|
2007
|
0.79
|
|
49
|
Zinc as a marker of affective disorders.
|
Pharmacol Rep
|
2013
|
0.79
|
|
50
|
Increase in synaptic hippocampal zinc concentration following chronic but not acute zinc treatment in rats.
|
Brain Res
|
2006
|
0.79
|
|
51
|
Serum trace elements in animal models and human depression: Part III. Magnesium. Relationship with copper.
|
Hum Psychopharmacol
|
2000
|
0.79
|
|
52
|
Zinc deficiency alters responsiveness to antidepressant drugs in mice.
|
Pharmacol Rep
|
2013
|
0.79
|
|
53
|
Synthesis and biological investigation of potential atypical antipsychotics with a tropane core. Part 1.
|
Eur J Med Chem
|
2011
|
0.79
|
|
54
|
Synthesis and preliminary pharmacological evaluation of imidazo[2,1-f]purine-2,4-dione derivatives.
|
Eur J Med Chem
|
2009
|
0.78
|
|
55
|
Alterations in hippocampal calcium-binding neurons induced by stress models of depression: a preliminary assessment.
|
Pharmacol Rep
|
2011
|
0.78
|
|
56
|
Antidepressant-like effect of chromium chloride in the mouse forced swim test: involvement of glutamatergic and serotonergic receptors.
|
Pharmacol Rep
|
2009
|
0.78
|
|
57
|
Involvement of NMDA and AMPA receptors in the antidepressant-like activity of antidepressant drugs in the forced swim test.
|
Pharmacol Rep
|
2013
|
0.78
|
|
58
|
Evaluation of oxidative status and depression-like responses in Brown Norway rats with acute myeloid leukemia.
|
Prog Neuropsychopharmacol Biol Psychiatry
|
2009
|
0.78
|
|
59
|
Effect of imipramine on brain D-1 and 5-HT-2A receptors in a chronic unpredictable stress model in rats.
|
Pol J Pharmacol
|
2002
|
0.78
|
|
60
|
Lack of NMDA-AMPA interaction in antidepressant-like effect of CGP 37849, an antagonist of NMDA receptor, in the forced swim test.
|
J Neural Transm (Vienna)
|
2008
|
0.78
|
|
61
|
Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT1A activity: part 2.
|
Eur J Med Chem
|
2009
|
0.78
|
|
62
|
Effects of acute and chronic treatment with magnesium in the forced swim test in rats.
|
Pharmacol Rep
|
2005
|
0.78
|
|
63
|
The molecular interactions of buspirone analogues with the serotonin transporter.
|
Bioorg Med Chem
|
2008
|
0.78
|
|
64
|
NMDA and AMPA receptors are involved in the antidepressant-like activity of tianeptine in the forced swim test in mice.
|
Pharmacol Rep
|
2011
|
0.77
|
|
65
|
Effect of chronic treatment with dexamethasone on brain dopamine receptors in mice.
|
Pol J Pharmacol
|
2004
|
0.77
|
|
66
|
Antidepressant-like activity of 8-Br-cAMP, a PKA activator, in the forced swim test.
|
J Neural Transm (Vienna)
|
2008
|
0.77
|
|
67
|
Anxiolytic-like activity of zinc in rodent tests.
|
Pharmacol Rep
|
2011
|
0.77
|
|
68
|
Medium supplementation with zinc enables detection of imipramine-induced adaptation in glycine/NMDA receptors labeled with [3H]L-689,560.
|
Pharmacol Rep
|
2006
|
0.77
|
|
69
|
Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT1A activity, part 1.
|
Eur J Med Chem
|
2008
|
0.77
|
|
70
|
[The role of zinc in the pathogenesis and treatment of affective disorders].
|
Psychiatr Pol
|
2005
|
0.77
|
|
71
|
Thiobarbituric Acid-Reactive Substances: Markers of an Acute Episode and a Late Stage of Bipolar Disorder.
|
Neuropsychobiology
|
2016
|
0.76
|
|
72
|
Synthesis and 5-HT(1A), 5-HT(2A) receptor activity of new beta-tetralonohydantoins.
|
Eur J Med Chem
|
2005
|
0.76
|
|
73
|
Early lifetime zinc supplementation protects zinc-deficient diet-induced alterations.
|
Pharmacol Rep
|
2011
|
0.76
|
|
74
|
Synthesis and biological evaluation of novel pyrrolidine-2,5-dione derivatives as potential antidepressant agents. Part 1.
|
Eur J Med Chem
|
2013
|
0.76
|
|
75
|
New arylpiperazine 5-HT(1A) receptor ligands containing the pyrimido[2,1-f]purine fragment: synthesis, in vitro, and in vivo pharmacological evaluation.
|
J Med Chem
|
2004
|
0.76
|
|
76
|
Synthesis, in vitro binding studies and docking of long-chain arylpiperazine nitroquipazine analogues, as potential serotonin transporter inhibitors.
|
Eur J Med Chem
|
2012
|
0.76
|
|
77
|
Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT(1A) activity. part 3.
|
Eur J Med Chem
|
2010
|
0.76
|
|
78
|
Synthesis, antidepressant evaluation and docking studies of long-chain alkylnitroquipazines as serotonin transporter inhibitors.
|
Chem Biol Drug Des
|
2013
|
0.75
|
|
79
|
Antidepressant-like activity of magnesium in the olfactory bulbectomy model is associated with the AMPA/BDNF pathway.
|
Psychopharmacology (Berl)
|
2014
|
0.75
|
|
80
|
Involvement of NMDA receptor complex in the anxiolytic-like effects of chlordiazepoxide in mice.
|
J Neural Transm (Vienna)
|
2011
|
0.75
|
|
81
|
[The role of copper and magnesium in the pathogenesis and treatment of affective disorders].
|
Psychiatr Pol
|
2005
|
0.75
|
|
82
|
Serotonin transporter activity of imidazolidine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives in aspect of their acid-base properties.
|
Med Chem Res
|
2011
|
0.75
|
|
83
|
Tissue distribution of gold nanoparticles after single intravenous administration in mice.
|
Pharmacol Rep
|
2013
|
0.75
|
|
84
|
Pharmacokinetic interaction after joint administration of zinc and imipramine in forced swim test in mice.
|
Pol J Pharmacol
|
2004
|
0.75
|
|
85
|
Effect of imipramine treatment on plasma dopamine beta-hydroxylase activity in chronic mild stress in rats.
|
Pol J Pharmacol
|
2005
|
0.75
|
|
86
|
Synthesis of new hexahydro- and octahydropyrido[1,2-c]pyrimidine derivatives with an arylpiperazine moiety as ligands for 5-HT1A and 5-HT2A receptors.
|
Farmaco
|
2002
|
0.75
|
|
87
|
Synthesis of new hexahydro- and octahydropyrido[1,2-c]pyrimidine derivatives with an arylpiperazine moiety as ligands for 5-HT1A and 5-HT2A receptors. Part 4.
|
Eur J Med Chem
|
2005
|
0.75
|
|
88
|
[Postpartum depression].
|
Przegl Lek
|
2002
|
0.75
|
|
89
|
Different pattern of changes in calcium binding proteins immunoreactivity in the medial prefrontal cortex of rats exposed to stress models of depression.
|
Pharmacol Rep
|
2011
|
0.75
|