| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
|
Nat Genet
|
2008
|
35.06
|
|
2
|
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
|
Nat Genet
|
2010
|
17.89
|
|
3
|
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
|
Nat Genet
|
2010
|
16.96
|
|
4
|
Richness of human gut microbiome correlates with metabolic markers.
|
Nature
|
2013
|
6.93
|
|
5
|
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.
|
Nat Genet
|
2010
|
6.66
|
|
6
|
Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants.
|
Nat Genet
|
2010
|
5.44
|
|
7
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
|
8
|
A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.
|
Nat Genet
|
2010
|
2.81
|
|
9
|
Estimation of allele frequency and association mapping using next-generation sequencing data.
|
BMC Bioinformatics
|
2011
|
1.93
|
|
10
|
Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm.
|
Nat Genet
|
2010
|
1.79
|
|
11
|
A genome-wide association search for type 2 diabetes genes in African Americans.
|
PLoS One
|
2012
|
1.72
|
|
12
|
Underlying genetic models of inheritance in established type 2 diabetes associations.
|
Am J Epidemiol
|
2009
|
1.60
|
|
13
|
Natural selection affects multiple aspects of genetic variation at putatively neutral sites across the human genome.
|
PLoS Genet
|
2011
|
1.54
|
|
14
|
Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry.
|
PLoS Genet
|
2013
|
1.51
|
|
15
|
Common type 2 diabetes risk gene variants associate with gestational diabetes.
|
J Clin Endocrinol Metab
|
2008
|
1.43
|
|
16
|
Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes.
|
Am J Hum Genet
|
2013
|
1.43
|
|
17
|
Genome-wide population-based association study of extremely overweight young adults--the GOYA study.
|
PLoS One
|
2011
|
1.34
|
|
18
|
Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study.
|
PLoS One
|
2009
|
1.29
|
|
19
|
Combined analyses of 20 common obesity susceptibility variants.
|
Diabetes
|
2010
|
1.27
|
|
20
|
G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans.
|
Diabetes
|
2009
|
1.27
|
|
21
|
Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism.
|
J Am Coll Cardiol
|
2012
|
1.14
|
|
22
|
Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with decreased β-cell function whereas risk alleles near ANKRD55 and GRB14 associate with decreased insulin sensitivity in the Danish Inter99 cohort.
|
J Clin Endocrinol Metab
|
2013
|
1.14
|
|
23
|
The KCNMB1 Glu65Lys polymorphism associates with reduced systolic and diastolic blood pressure in the Inter99 study of 5729 Danes.
|
J Hypertens
|
2008
|
1.13
|
|
24
|
PC-1 amino acid variant (K121Q) has no impact on progression of diabetic nephropathy in type 1 diabetic patients.
|
Nephrol Dial Transplant
|
2002
|
1.13
|
|
25
|
Variants near MC4R are associated with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes.
|
Diabetes
|
2008
|
1.05
|
|
26
|
Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus.
|
Am J Hum Genet
|
2010
|
1.01
|
|
27
|
Studies of the association of Arg72Pro of tumor suppressor protein p53 with type 2 diabetes in a combined analysis of 55,521 Europeans.
|
PLoS One
|
2011
|
0.92
|
|
28
|
Do gene variants influencing adult adiposity affect birth weight? A population-based study of 24 loci in 4,744 Danish individuals.
|
PLoS One
|
2010
|
0.92
|
|
29
|
Common variation in LMNA increases susceptibility to type 2 diabetes and associates with elevated fasting glycemia and estimates of body fat and height in the general population: studies of 7,495 Danish whites.
|
Diabetes
|
2007
|
0.91
|
|
30
|
What is the contribution of two genetic variants regulating VEGF levels to type 2 diabetes risk and to microvascular complications?
|
PLoS One
|
2013
|
0.90
|
|
31
|
MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans.
|
Diabetes
|
2010
|
0.86
|
|
32
|
No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels.
|
Diabetes
|
2012
|
0.86
|
|
33
|
Genetic variant SLC2A2 [corrected] Is associated with risk of cardiovascular disease – assessing the individual and cumulative effect of 46 type 2 diabetes related genetic variants.
|
PLoS One
|
2012
|
0.83
|
|
34
|
The birth weight lowering C-allele of rs900400 near LEKR1 and CCNL1 associates with elevated insulin release following an oral glucose challenge.
|
PLoS One
|
2011
|
0.83
|
|
35
|
The PNPLA3 rs738409 G-allele associates with reduced fasting serum triglyceride and serum cholesterol in Danes with impaired glucose regulation.
|
PLoS One
|
2012
|
0.81
|
|
36
|
MTHFR C677T genotype and cardiovascular risk in a general population without mandatory folic acid fortification.
|
Eur J Nutr
|
2014
|
0.80
|
|
37
|
Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease.
|
PLoS One
|
2011
|
0.80
|
|
38
|
Discovery of coding genetic variants influencing diabetes-related serum biomarkers and their impact on risk of type 2 diabetes.
|
J Clin Endocrinol Metab
|
2015
|
0.79
|
|
39
|
Genetic and phenotypic correlations between surrogate measures of insulin release obtained from OGTT data.
|
Diabetologia
|
2015
|
0.77
|
|
40
|
Impact of rs361072 in the phosphoinositide 3-kinase p110beta gene on whole-body glucose metabolism and subunit protein expression in skeletal muscle.
|
Diabetes
|
2010
|
0.76
|
|
41
|
Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes.
|
BMC Med Genet
|
2013
|
0.76
|
|
42
|
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
|
PLoS Genet
|
2016
|
0.75
|
|
43
|
Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
|
PLoS Genet
|
2017
|
0.75
|
|
44
|
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals.
|
Circ Cardiovasc Genet
|
2017
|
0.75
|