Published in FEBS J on January 15, 2010
Function of alternative splicing. Gene (2012) 2.00
Long lasting control of viral rebound with a new drug ABX464 targeting Rev - mediated viral RNA biogenesis. Retrovirology (2015) 1.00
Differential effect of CLK SR Kinases on HIV-1 gene expression: potential novel targets for therapy. Retrovirology (2011) 0.99
Influenza viruses and mRNA splicing: doing more with less. MBio (2014) 0.95
Digoxin suppresses HIV-1 replication by altering viral RNA processing. PLoS Pathog (2013) 0.95
A multifunctional bioconjugate module for versatile photoaffinity labeling and click chemistry of RNA. Nucleic Acids Res (2011) 0.90
Models for predicting effective HIV chemoprevention in women. J Acquir Immune Defic Syndr (2015) 0.87
Converging strategies in expression of human complex retroviruses. Viruses (2011) 0.86
Characterization of novel inhibitors of HIV-1 replication that function via alteration of viral RNA processing and rev function. Nucleic Acids Res (2013) 0.84
Stably integrated and expressed retroviral sequences can influence nuclear location and chromatin condensation of the integration locus. Chromosoma (2012) 0.82
Pharmacodynamic assays to facilitate preclinical and clinical development of pre-mRNA splicing modulatory drug candidates. Pharmacol Res Perspect (2015) 0.81
Food effect on pharmacokinetic parameters of ABX464 administered orally: a randomized trial in healthy male subjects. Antimicrob Agents Chemother (2016) 0.80
Isolation of a TRAIL antagonist from the serum of HIV-infected patients. J Biol Chem (2011) 0.80
Natural single-nucleotide polymorphisms in the 3' region of the HIV-1 pol gene modulate viral replication ability. J Virol (2014) 0.79
HIV-1 Vpr N-terminal tagging affects alternative splicing of the viral genome. Sci Rep (2016) 0.78
Safety, Pharmacokinetics, and Antiviral Activity of a Novel HIV Antiviral, ABX464, in Treatment-Naive HIV-Infected Subjects in a Phase 2 Randomized, Controlled Study. Antimicrob Agents Chemother (2017) 0.76
Human Papillomavirus E2 Protein: Linking Replication, Transcription, and RNA Processing. J Virol (2016) 0.76
Embryonic expression of endogenous retroviral RNAs in somatic tissues adjacent to the Oikopleura germline. Nucleic Acids Res (2015) 0.76
Translational Control of the HIV Unspliced Genomic RNA. Viruses (2015) 0.76
Modulation of the splicing regulatory function of SRSF10 by a novel compound that impairs HIV-1 replication. Nucleic Acids Res (2016) 0.76
Putting an 'End' to HIV mRNAs: capping and polyadenylation as potential therapeutic targets. AIDS Res Ther (2013) 0.76
Alternative splicing regulated by butyrate in bovine epithelial cells. PLoS One (2012) 0.75
Can the HIV-1 splicing machinery be targeted for drug discovery? HIV AIDS (Auckl) (2017) 0.75
Functional bottlenecks for generation of HIV-1 intersubtype Env recombinants. Retrovirology (2015) 0.75
Argonaute proteins regulate HIV-1 multiply spliced RNA and viral production in a Dicer independent manner. Nucleic Acids Res (2017) 0.75
Expression of Herpes Simplex Virus Thymidine Kinase/Ganciclovir by RNA Trans-Splicing Induces Selective Killing of HIV-Producing Cells. Mol Ther Nucleic Acids (2017) 0.75
Alternative splicing and disease. Biochim Biophys Acta (2008) 3.47
2-D structure of the A region of Xist RNA and its implication for PRC2 association. PLoS Biol (2010) 2.30
Drosophila PTB promotes formation of high-order RNP particles and represses oskar translation. Genes Dev (2009) 2.16
The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery. J Cell Biol (2008) 1.95
RNomics in Archaea reveals a further link between splicing of archaeal introns and rRNA processing. Nucleic Acids Res (2002) 1.89
Reconstitution of archaeal H/ACA small ribonucleoprotein complexes active in pseudouridylation. Nucleic Acids Res (2005) 1.65
Identification of modified residues in RNAs by reverse transcription-based methods. Methods Enzymol (2007) 1.48
Selective modification of alternative splicing by indole derivatives that target serine-arginine-rich protein splicing factors. Proc Natl Acad Sci U S A (2005) 1.45
The Saccharomyces cerevisiae U2 snRNA:pseudouridine-synthase Pus7p is a novel multisite-multisubstrate RNA:Psi-synthase also acting on tRNAs. RNA (2003) 1.33
A Janus splicing regulatory element modulates HIV-1 tat and rev mRNA production by coordination of hnRNP A1 cooperative binding. J Mol Biol (2002) 1.30
Antagonistic factors control the unproductive splicing of SC35 terminal intron. Nucleic Acids Res (2009) 1.28
Crystal structure determination and site-directed mutagenesis of the Pyrococcus abyssi aCBF5-aNOP10 complex reveal crucial roles of the C-terminal domains of both proteins in H/ACA sRNP activity. Nucleic Acids Res (2006) 1.24
Control of RNP motility and localization by a splicing-dependent structure in oskar mRNA. Nat Struct Mol Biol (2012) 1.21
Small-molecule inhibition of HIV pre-mRNA splicing as a novel antiretroviral therapy to overcome drug resistance. PLoS Pathog (2007) 1.18
Differential effects of the SR proteins 9G8, SC35, ASF/SF2, and SRp40 on the utilization of the A1 to A5 splicing sites of HIV-1 RNA. J Biol Chem (2004) 1.16
Direct probing of RNA structure and RNA-protein interactions in purified HeLa cell's and yeast spliceosomal U4/U6.U5 tri-snRNP particles. J Mol Biol (2002) 1.12
In vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation protein. J Biol Chem (2007) 1.08
A conserved splicing mechanism of the LMNA gene controls premature aging. Hum Mol Genet (2011) 1.07
The strong efficiency of the Escherichia coli gapA P1 promoter depends on a complex combination of functional determinants. Biochem J (2004) 1.06
Biochemical and NMR study on the competition between proteins SC35, SRp40, and heterogeneous nuclear ribonucleoprotein A1 at the HIV-1 Tat exon 2 splicing site. J Biol Chem (2006) 1.05
A previously unidentified activity of yeast and mouse RNA:pseudouridine synthases 1 (Pus1p) on tRNAs. RNA (2006) 1.05
Combined in silico and experimental identification of the Pyrococcus abyssi H/ACA sRNAs and their target sites in ribosomal RNAs. Nucleic Acids Res (2008) 1.04
Selective inhibition of topoisomerase I and various steps of spliceosome assembly by diospyrin derivatives. Mol Pharmacol (2004) 0.99
Identification of determinants in the protein partners aCBF5 and aNOP10 necessary for the tRNA:Psi55-synthase and RNA-guided RNA:Psi-synthase activities. Nucleic Acids Res (2007) 0.99
Pseudouridylation at position 32 of mitochondrial and cytoplasmic tRNAs requires two distinct enzymes in Saccharomyces cerevisiae. J Biol Chem (2004) 0.98
A second base pair interaction between U3 small nucleolar RNA and the 5'-ETS region is required for early cleavage of the yeast pre-ribosomal RNA. Nucleic Acids Res (2011) 0.98
Analysis of exonic regions involved in nuclear localization, splicing activity, and dimerization of Muscleblind-like-1 isoforms. J Biol Chem (2011) 0.94
Identification of protein partners of the human immunodeficiency virus 1 tat/rev exon 3 leads to the discovery of a new HIV-1 splicing regulator, protein hnRNP K. RNA Biol (2011) 0.90
Purification, crystallization and preliminary X-ray diffraction data of L7Ae sRNP core protein from Pyrococcus abyssii. Acta Crystallogr D Biol Crystallogr (2003) 0.90
Characterization of the molecular mechanisms involved in the differential production of erythrose-4-phosphate dehydrogenase, 3-phosphoglycerate kinase and class II fructose-1,6-bisphosphate aldolase in Escherichia coli. Mol Microbiol (2005) 0.90
High-resolution structural analysis shows how Tah1 tethers Hsp90 to the R2TP complex. Structure (2013) 0.90
Role of RNA structure and protein factors in the control of HIV-1 splicing. Front Biosci (Landmark Ed) (2009) 0.86
Deficiency of the tRNATyr:Psi 35-synthase aPus7 in Archaea of the Sulfolobales order might be rescued by the H/ACA sRNA-guided machinery. Nucleic Acids Res (2009) 0.86
A dedicated computational approach for the identification of archaeal H/ACA sRNAs. Methods Enzymol (2007) 0.85
RNA sequence and two-dimensional structure features required for efficient substrate modification by the Saccharomyces cerevisiae RNA:{Psi}-synthase Pus7p. J Biol Chem (2008) 0.85
Characterization of the interaction between protein Snu13p/15.5K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assembly. Nucleic Acids Res (2013) 0.84
Reconstitution of archaeal H/ACA sRNPs and test of their activity. Methods Enzymol (2007) 0.82
Drosophila Ge-1 promotes P body formation and oskar mRNA localization. PLoS One (2011) 0.81
Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle. Nucleic Acids Res (2012) 0.80
Prospective evaluation of quality of life 54 months after high-dose intensity-modulated radiotherapy for localized prostate cancer. Radiat Oncol (2013) 0.79
The Saccharomyces cerevisiae Pus2 protein encoded by YGL063w ORF is a mitochondrial tRNA:Psi27/28-synthase. RNA (2007) 0.79
The sRNA RyhB regulates the synthesis of the Escherichia coli methionine sulfoxide reductase MsrB but not MsrA. PLoS One (2013) 0.78
Concurrent radiation therapy and lenalidomide in myeloma patient. Radiother Oncol (2008) 0.77
Comparative study of two box H/ACA ribonucleoprotein pseudouridine-synthases: relation between conformational dynamics of the guide RNA, enzyme assembly and activity. PLoS One (2013) 0.77
A 3'-terminal minihelix in the precursor of human spliceosomal U2 small nuclear RNA. J Biol Chem (2002) 0.77
(1)H, (15)N and (13)C resonance assignments of the two TPR domains from the human RPAP3 protein. Biomol NMR Assign (2014) 0.76
Probing small non-coding RNAs structures. Methods Mol Biol (2015) 0.76
[Concurrent whole-brain radiotherapy with trastuzumab for treatment of brain metastases in breast cancer patients: questions and answers]. Bull Cancer (2011) 0.76
Fluorescence in situ hybridization of small non-coding RNAs. Methods Mol Biol (2015) 0.76
Preliminary experience of whole-brain radiation therapy (WBRT) in breast cancer patients with brain metastases previously treated with bevacizumab-based chemotherapy. J Neurooncol (2011) 0.76
Structural and functional analysis of the Rous Sarcoma virus negative regulator of splicing and demonstration of its activation by the 9G8 SR protein. Nucleic Acids Res (2010) 0.75
Engineering of a DNA polymerase for direct m6A sequencing. Angew Chem Int Ed Engl (2017) 0.75
Quantification and quality control of a small non-coding RNA preparation. Methods Mol Biol (2015) 0.75