| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
|
Nature
|
2011
|
13.25
|
|
2
|
Genome-wide association study identifies eight loci associated with blood pressure.
|
Nat Genet
|
2009
|
12.44
|
|
3
|
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.
|
Lancet
|
2012
|
4.87
|
|
4
|
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.
|
Nat Genet
|
2012
|
4.73
|
|
5
|
Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease.
|
Nat Genet
|
2009
|
4.63
|
|
6
|
Identification of seven loci affecting mean telomere length and their association with disease.
|
Nat Genet
|
2013
|
3.87
|
|
7
|
Genetic loci influencing kidney function and chronic kidney disease.
|
Nat Genet
|
2010
|
3.75
|
|
8
|
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction.
|
Nat Genet
|
2010
|
3.55
|
|
9
|
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
|
Nat Genet
|
2013
|
3.25
|
|
10
|
New gene functions in megakaryopoiesis and platelet formation.
|
Nature
|
2011
|
3.14
|
|
11
|
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
|
Nat Genet
|
2012
|
3.04
|
|
12
|
Common variants near TERC are associated with mean telomere length.
|
Nat Genet
|
2010
|
2.98
|
|
13
|
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.
|
PLoS Genet
|
2013
|
2.83
|
|
14
|
FTO genotype is associated with phenotypic variability of body mass index.
|
Nature
|
2012
|
2.77
|
|
15
|
CUBN is a gene locus for albuminuria.
|
J Am Soc Nephrol
|
2011
|
2.70
|
|
16
|
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
|
Am J Hum Genet
|
2012
|
2.53
|
|
17
|
Incidence and epidemiology of new onset heart failure with preserved vs. reduced ejection fraction in a community-based cohort: 11-year follow-up of PREVEND.
|
Eur Heart J
|
2013
|
2.32
|
|
18
|
Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension.
|
PLoS Genet
|
2010
|
2.24
|
|
19
|
Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study.
|
J Am Coll Cardiol
|
2013
|
2.18
|
|
20
|
Healthy aging and disease: role for telomere biology?
|
Clin Sci (Lond)
|
2011
|
2.10
|
|
21
|
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption.
|
Proc Natl Acad Sci U S A
|
2011
|
2.01
|
|
22
|
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
Am J Hum Genet
|
2012
|
1.96
|
|
23
|
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
|
Nat Genet
|
2013
|
1.72
|
|
24
|
Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activation of protein kinase A.
|
Arterioscler Thromb Vasc Biol
|
2010
|
1.68
|
|
25
|
Genetic and pharmacological inhibition of galectin-3 prevents cardiac remodeling by interfering with myocardial fibrogenesis.
|
Circ Heart Fail
|
2012
|
1.67
|
|
26
|
The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies.
|
BMC Endocr Disord
|
2014
|
1.64
|
|
27
|
Biological ageing and cardiovascular disease.
|
Heart
|
2008
|
1.64
|
|
28
|
Erythropoietin improves cardiac function through endothelial progenitor cell and vascular endothelial growth factor mediated neovascularization.
|
Eur Heart J
|
2007
|
1.62
|
|
29
|
Erythropoietin stimulates normal endothelial progenitor cell-mediated endothelial turnover, but attributes to neovascularization only in the presence of local ischemia.
|
Cardiovasc Drugs Ther
|
2008
|
1.57
|
|
30
|
Urinary and plasma magnesium and risk of ischemic heart disease.
|
Am J Clin Nutr
|
2013
|
1.54
|
|
31
|
Leukocyte telomere length in healthy Caucasian and African-American adolescents: relationships with race, sex, adiposity, adipokines, and physical activity.
|
J Pediatr
|
2010
|
1.50
|
|
32
|
Predictors of angiotensin-converting enzyme inhibitor-induced reduction of urinary albumin excretion in nondiabetic patients.
|
Hypertension
|
2006
|
1.49
|
|
33
|
Plasma renin and outcome in the community: data from PREVEND.
|
Eur Heart J
|
2012
|
1.47
|
|
34
|
Effects of angiotensin II and angiotensin II type 1 receptor blockade on neointimal formation after stent implantation.
|
Int J Cardiol
|
2007
|
1.46
|
|
35
|
Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.
|
Arterioscler Thromb Vasc Biol
|
2014
|
1.45
|
|
36
|
Blood pressure loci identified with a gene-centric array.
|
Am J Hum Genet
|
2011
|
1.44
|
|
37
|
Telomere biology in healthy aging and disease.
|
Pflugers Arch
|
2009
|
1.41
|
|
38
|
Plasma matrix metalloproteinase-9 and ACE-inhibitor-induced improvement of urinary albumin excretion in non-diabetic, microalbuminuric subjects.
|
J Renin Angiotensin Aldosterone Syst
|
2007
|
1.37
|
|
39
|
Loci influencing blood pressure identified using a cardiovascular gene-centric array.
|
Hum Mol Genet
|
2013
|
1.27
|
|
40
|
Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation.
|
Blood
|
2012
|
1.26
|
|
41
|
Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies.
|
Circ Cardiovasc Genet
|
2011
|
1.26
|
|
42
|
Differential associations between renal function and "modifiable" risk factors in patients with chronic heart failure.
|
Clin Res Cardiol
|
2008
|
1.22
|
|
43
|
Genetic architecture of ambulatory blood pressure in the general population: insights from cardiovascular gene-centric array.
|
Hypertension
|
2010
|
1.22
|
|
44
|
A Simple and Computationally Efficient Approach to Multifactor Dimensionality Reduction Analysis of Gene-Gene Interactions for Quantitative Traits.
|
PLoS One
|
2013
|
1.20
|
|
45
|
Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms.
|
Circulation
|
2009
|
1.20
|
|
46
|
Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci.
|
Genome Res
|
2013
|
1.10
|
|
47
|
Telomere length and psychological well-being in patients with chronic heart failure.
|
Age Ageing
|
2010
|
1.04
|
|
48
|
Association between left ventricular mass and telomere length in a population study.
|
Am J Epidemiol
|
2010
|
1.02
|
|
49
|
Aging, telomeres and heart failure.
|
Heart Fail Rev
|
2010
|
1.02
|
|
50
|
Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy.
|
Circ Cardiovasc Genet
|
2011
|
0.99
|
|
51
|
Telomere biology in cardiovascular disease: the TERC-/- mouse as a model for heart failure and ageing.
|
Cardiovasc Res
|
2008
|
0.99
|
|
52
|
Low-dose erythropoietin improves cardiac function in experimental heart failure without increasing haematocrit.
|
Eur J Heart Fail
|
2008
|
0.98
|
|
53
|
Telomere length of circulating leukocyte subpopulations and buccal cells in patients with ischemic heart failure and their offspring.
|
PLoS One
|
2011
|
0.97
|
|
54
|
Bone marrow dysfunction in chronic heart failure patients.
|
Eur J Heart Fail
|
2010
|
0.97
|
|
55
|
GWAS identifies an NAT2 acetylator status tag single nucleotide polymorphism to be a major locus for skin fluorescence.
|
Diabetologia
|
2014
|
0.97
|
|
56
|
A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol.
|
PLoS Genet
|
2011
|
0.97
|
|
57
|
Bradykinin protects against oxidative stress-induced endothelial cell senescence.
|
Hypertension
|
2008
|
0.96
|
|
58
|
Circulating leukocyte and carotid atherosclerotic plaque telomere length: interrelation, association with plaque characteristics, and restenosis after endarterectomy.
|
Arterioscler Thromb Vasc Biol
|
2011
|
0.95
|
|
59
|
Pathway analysis shows association between FGFBP1 and hypertension.
|
J Am Soc Nephrol
|
2011
|
0.95
|
|
60
|
Metformin in non-diabetic patients presenting with ST elevation myocardial infarction: rationale and design of the glycometabolic intervention as adjunct to primary percutaneous intervention in ST elevation myocardial infarction (GIPS)-III trial.
|
Cardiovasc Drugs Ther
|
2012
|
0.94
|
|
61
|
Use of cystatin C levels in estimating renal function and prognosis in patients with chronic systolic heart failure.
|
Heart
|
2011
|
0.94
|
|
62
|
Activation of liver X receptor-alpha reduces activation of the renal and cardiac renin-angiotensin-aldosterone system.
|
Lab Invest
|
2010
|
0.94
|
|
63
|
Clinical impact of vasomotor function assessment and the role of ACE-inhibitors and statins.
|
Vascul Pharmacol
|
2005
|
0.90
|
|
64
|
A genome-wide association study of circulating galectin-3.
|
PLoS One
|
2012
|
0.89
|
|
65
|
Sex differences in new-onset heart failure.
|
Clin Res Cardiol
|
2014
|
0.89
|
|
66
|
The emerging role of telomere biology in cardiovascular disease.
|
Front Biosci (Landmark Ed)
|
2010
|
0.89
|
|
67
|
Genome-wide meta-analysis of common variant differences between men and women.
|
Hum Mol Genet
|
2012
|
0.88
|
|
68
|
Activation of liver X receptors with T0901317 attenuates cardiac hypertrophy in vivo.
|
Eur J Heart Fail
|
2010
|
0.88
|
|
69
|
Peroxiredoxin 4, a novel circulating biomarker for oxidative stress and the risk of incident cardiovascular disease and all-cause mortality.
|
J Am Heart Assoc
|
2012
|
0.87
|
|
70
|
Can critically short telomeres cause functional exhaustion of progenitor cells in postinfarction heart failure?
|
J Am Coll Cardiol
|
2007
|
0.86
|
|
71
|
Pharmacoepigenetics in heart failure.
|
Curr Heart Fail Rep
|
2010
|
0.86
|
|
72
|
Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-pro-endothelin-1.
|
Hypertension
|
2013
|
0.86
|
|
73
|
Renal dysfunction is associated with shorter telomere length in heart failure.
|
Clin Res Cardiol
|
2009
|
0.85
|
|
74
|
Anaemia is associated with shorter leucocyte telomere length in patients with chronic heart failure.
|
Eur J Heart Fail
|
2010
|
0.85
|
|
75
|
Telomere biology in heart failure.
|
Eur J Heart Fail
|
2008
|
0.85
|
|
76
|
Ischemic patterns assessed by positron emission tomography predict adverse outcome in patients with idiopathic dilated cardiomyopathy.
|
J Nucl Cardiol
|
2009
|
0.84
|
|
77
|
Search for a correlation between telomere length and severity of retinitis pigmentosa due to the dominant rhodopsin Pro23His mutation.
|
Mol Vis
|
2009
|
0.83
|
|
78
|
Influence of age on the prognostic value of mid-regional pro-adrenomedullin in the general population.
|
Heart
|
2012
|
0.83
|
|
79
|
Chronic metformin treatment is associated with reduced myocardial infarct size in diabetic patients with ST-segment elevation myocardial infarction.
|
Cardiovasc Drugs Ther
|
2014
|
0.81
|
|
80
|
Pharmacogenetics in heart failure: promises and challenges.
|
Expert Opin Pharmacother
|
2009
|
0.80
|
|
81
|
Nuclear hormone receptors as regulators of the renin-angiotensin-aldosterone system.
|
Hypertension
|
2008
|
0.80
|
|
82
|
Dissecting the genetics of complex traits: lessons from hypertension.
|
Nephrol Dial Transplant
|
2010
|
0.80
|
|
83
|
Reproducibility of Telomere Length Assessment - An International Collaborative Study.
|
Int J Epidemiol
|
2015
|
0.80
|
|
84
|
Intensive versus moderate lipid lowering with statins after acute coronary syndromes.
|
N Engl J Med
|
2004
|
0.80
|
|
85
|
Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium.
|
Atherosclerosis
|
2012
|
0.79
|
|
86
|
Expanding the concept of telomere dysfunction in cardiovascular disease.
|
Arterioscler Thromb Vasc Biol
|
2008
|
0.79
|
|
87
|
Genome-wide meta-analyses of plasma renin activity and concentration reveal association with the kininogen 1 and prekallikrein genes.
|
Circ Cardiovasc Genet
|
2014
|
0.78
|
|
88
|
CCR5Delta32 genotype is associated with outcome in type 2 diabetes mellitus.
|
Diabetes Res Clin Pract
|
2009
|
0.77
|
|
89
|
Circulating peroxiredoxin 4 and type 2 diabetes risk: the Prevention of Renal and Vascular Endstage Disease (PREVEND) study.
|
Diabetologia
|
2014
|
0.77
|
|
90
|
Short-term statin therapy and cardiac function and symptoms in patients with idiopathic dilated cardiomyopathy.
|
Circulation
|
2004
|
0.76
|
|
91
|
Statins and autonomic function in chronic heart failure.
|
Cardiovasc Drugs Ther
|
2005
|
0.76
|
|
92
|
The association between intelligence and telomere length: a longitudinal population based study.
|
PLoS One
|
2012
|
0.75
|
|
93
|
Online journals: paying or delaying?
|
Lancet
|
2010
|
0.75
|
|
94
|
Letter by Huzen et al regarding article, "Association of leukocyte telomere length with circulating biomarkers of the renin-angiotensin-aldosterone system: the Framingham Heart Study".
|
Circulation
|
2008
|
0.75
|
|
95
|
Aggressive lipid-lowering therapy and regression of coronary atheroma.
|
JAMA
|
2004
|
0.75
|
|
96
|
Effect of Metformin on Renal Function After Primary Percutaneous Coronary Intervention in Patients Without Diabetes Presenting with ST-elevation Myocardial Infarction: Data from the GIPS-III Trial.
|
Cardiovasc Drugs Ther
|
2015
|
0.75
|
|
97
|
Telomere length and outcomes in ischaemic heart failure: data from the COntrolled ROsuvastatin multiNAtional Trial in Heart Failure (CORONA).
|
Eur J Heart Fail
|
2015
|
0.75
|
|
98
|
HFpEF vs. HFrEF: can microRNAs advance the diagnosis?
|
Eur J Heart Fail
|
2015
|
0.75
|
|
99
|
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
|
PLoS Genet
|
2016
|
0.75
|
|
100
|
Should non-cardiovascular mortality be considered in the SCORE model? Findings from the Prevention of Renal and Vascular End-stage Disease (PREVEND) cohort.
|
Eur J Epidemiol
|
2014
|
0.75
|
|
101
|
Long-term effects of pravastatin and fosinopril on peripheral endothelial function in albuminuric subjects.
|
Atherosclerosis
|
2006
|
0.75
|
|
102
|
The Nobel Prize for medicine for telomere biology and relevance to heart failure research.
|
Eur J Heart Fail
|
2009
|
0.75
|
|
103
|
Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.
|
Nat Genet
|
2017
|
0.75
|
|
104
|
Refining Thromboembolic Risk in the General Population.
|
J Am Coll Cardiol
|
2017
|
0.75
|
|
105
|
Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.
|
Nat Genet
|
2017
|
0.75
|
|
106
|
Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels.
|
Thromb Haemost
|
2016
|
0.75
|
|
107
|
Telomere Length and Risk of Cardiovascular Disease and Cancer.
|
J Am Coll Cardiol
|
2017
|
0.75
|
|
108
|
Reply: Poor Sensitivity and Specificity of Electrocardiographic Estimation of Myocardial Mass.
|
J Am Coll Cardiol
|
2017
|
0.75
|
|
109
|
Left ventricular ejection fraction and mortality in patients with ST-elevation myocardial infarction and bundle branch block.
|
Coron Artery Dis
|
2016
|
0.75
|
|
110
|
Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk.
|
Nat Commun
|
2017
|
0.75
|
|
111
|
Corrigendum: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.
|
Nat Commun
|
2015
|
0.75
|
|
112
|
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals.
|
Circ Cardiovasc Genet
|
2017
|
0.75
|
|
113
|
Genome-wide association studies identify genetic loci for low von Willebrand factor levels.
|
Eur J Hum Genet
|
2016
|
0.75
|