John D Clements

Author PubWeight™ 59.04‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The 'permeome' of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum. Genome Biol 2005 1.91
2 Presynaptic Ca2+ channels: a functional patchwork. Trends Neurosci 2003 1.57
3 Impact of vaccine-induced mucosal high-avidity CD8+ CTLs in delay of AIDS viral dissemination from mucosa. Blood 2005 1.54
4 Characterization of a mutant Escherichia coli heat-labile toxin, LT(R192G/L211A), as a safe and effective oral adjuvant. Clin Vaccine Immunol 2011 1.51
5 Broadly protective Shigella vaccine based on type III secretion apparatus proteins. Infect Immun 2011 1.41
6 CD4 T cells are the only lymphocytes needed to protect mice against rotavirus shedding after intranasal immunization with a chimeric VP6 protein and the adjuvant LT(R192G). J Virol 2002 1.32
7 Evidence for peripheral clearance of cerebral Abeta protein following chronic, active Abeta immunization in PSAPP mice. Neurobiol Dis 2003 1.32
8 Effect of homologous and heterologous prime-boost on the immune response to recombinant plague antigens. Vaccine 2005 1.27
9 Options for inactivation, adjuvant, and route of topical administration of a killed, unencapsulated pneumococcal whole-cell vaccine. Clin Vaccine Immunol 2010 1.25
10 Kinetics of immune responses to influenza virus-like particles and dose-dependence of protection with a single vaccination. J Virol 2009 1.20
11 Intranasal immunotherapy for the treatment of Alzheimer's disease: Escherichia coli LT and LT(R192G) as mucosal adjuvants. Neurobiol Aging 2002 1.15
12 Protection against aerosolized Yersinia pestis challenge following homologous and heterologous prime-boost with recombinant plague antigens. Infect Immun 2005 1.14
13 Toward the development of a stable, freeze-dried formulation of Helicobacter pylori killed whole cell vaccine adjuvanted with a novel mutant of Escherichia coli heat-labile toxin. Vaccine 2009 1.11
14 Defending the mucosa: adjuvant and carrier formulations for mucosal immunity. Curr Opin Immunol 2011 1.10
15 Oral immunogenicity of human papillomavirus-like particles expressed in potato. J Virol 2003 1.09
16 Presynaptic and postsynaptic mechanisms underlie paired pulse depression at single GABAergic boutons in rat collicular cultures. J Physiol 2002 1.08
17 Binding site stoichiometry and the effects of phosphorylation on human alpha1 homomeric glycine receptors. J Physiol 2002 1.06
18 Assessment of the duration of protection in Campylobacter jejuni experimental infection in humans. Infect Immun 2010 1.05
19 Association of gamma interferon and interleukin-17 production in intestinal CD4+ T cells with protection against rotavirus shedding in mice intranasally immunized with VP6 and the adjuvant LT(R192G). J Virol 2007 1.04
20 Intranasal administration of an Escherichia coli-expressed codon-optimized rotavirus VP6 protein induces protection in mice. Protein Expr Purif 2004 1.03
21 Characterization of a novel fusion protein from IpaB and IpaD of Shigella spp. and its potential as a pan-Shigella vaccine. Infect Immun 2013 1.02
22 Bioencapsulation of the hepatitis B surface antigen and its use as an effective oral immunogen. Vaccine 2012 0.98
23 Antigen-specific memory T cell responses after vaccination with an oral killed cholera vaccine in Bangladeshi children and comparison to responses in patients with naturally acquired cholera. Clin Vaccine Immunol 2012 0.98
24 Development of a Bacillus subtilis-based rotavirus vaccine. Clin Vaccine Immunol 2010 0.98
25 Intranasal or oral immunization of inbred and outbred mice with murine or human rotavirus VP6 proteins protects against viral shedding after challenge with murine rotaviruses. Vaccine 2002 0.98
26 Effect of adjuvants and route of immunizations on the immune response to recombinant plague antigens. Vaccine 2007 0.97
27 IFN-gamma is the only anti-rotavirus cytokine found after in vitro stimulation of memory CD4+ T cells from mice immunized with a chimeric VP6 protein. Viral Immunol 2007 0.97
28 Comparison of taurine- and glycine-induced conformational changes in the M2-M3 domain of the glycine receptor. J Biol Chem 2004 0.97
29 Mice develop effective but delayed protective immune responses when immunized as neonates either intranasally with nonliving VP6/LT(R192G) or orally with live rhesus rotavirus vaccine candidates. J Virol 2006 0.97
30 Role of B7 costimulatory molecules in the adjuvant activity of the heat-labile enterotoxin of Escherichia coli. J Immunol 2002 0.96
31 Prophylactic administration of bacterially derived immunomodulators improves the outcome of influenza virus infection in a murine model. J Virol 2010 0.95
32 Effectiveness of the quillaja saponin semi-synthetic analog GPI-0100 in potentiating mucosal and systemic responses to recombinant HagB from Porphyromonas gingivalis. Vaccine 2003 0.95
33 The A subunit of Escherichia coli heat-labile enterotoxin functions as a mucosal adjuvant and promotes IgG2a, IgA, and Th17 responses to vaccine antigens. Infect Immun 2012 0.93
34 The level of protection against rotavirus shedding in mice following immunization with a chimeric VP6 protein is dependent on the route and the coadministered adjuvant. Vaccine 2002 0.92
35 Abeta1-15 is less immunogenic than Abeta1-40/42 for intranasal immunization of wild-type mice but may be effective for "boosting". Vaccine 2003 0.91
36 Kinetic analysis and evaluation of the mechanisms involved in the resolution of experimental nontypeable Haemophilus influenzae-induced otitis media after transcutaneous immunization. Vaccine 2012 0.90
37 Functional mapping of protective epitopes within the rotavirus VP6 protein in mice belonging to different haplotypes. Vaccine 2003 0.90
38 Evaluation of immunogenicity and protective efficacy of orally delivered Shigella type III secretion system proteins IpaB and IpaD. Vaccine 2013 0.89
39 Protection against rotavirus shedding after intranasal immunization of mice with a chimeric VP6 protein does not require intestinal IgA. Virology 2006 0.89
40 The adjuvant double mutant Escherichia coli heat labile toxin enhances IL-17A production in human T cells specific for bacterial vaccine antigens. PLoS One 2012 0.88
41 Single epitope mucosal vaccine delivered via immuno-stimulating complexes induces low level of immunity against simian-HIV. Vaccine 2006 0.87
42 Intrarectal immunization of mice with VP6 and either LT(R192G) or CTA1-DD as adjuvant protects against fecal rotavirus shedding after EDIM challenge. Vaccine 2007 0.87
43 Evaluation of combinatorial vaccines against anthrax and plague in a murine model. Vaccine 2007 0.86
44 Adenosine triphosphate acts as both a competitive antagonist and a positive allosteric modulator at recombinant N-methyl-D-aspartate receptors. Mol Pharmacol 2004 0.86
45 Hydration effects on skin microstructure as probed by high-resolution cryo-scanning electron microscopy and mechanistic implications to enhanced transcutaneous delivery of biomacromolecules. J Pharm Sci 2010 0.85
46 Characterization of heat-stable (STa) toxoids of enterotoxigenic Escherichia coli fused to double mutant heat-labile toxin peptide in inducing neutralizing Anti-STa antibodies. Infect Immun 2014 0.84
47 Identification of an immunodominant CD4+ T cell epitope in the VP6 protein of rotavirus following intranasal immunization of BALB/c mice. Virology 2007 0.84
48 Effectiveness of the B subunit of cholera toxin in potentiating immune responses to the recombinant hemagglutinin/adhesin domain of the gingipain Kgp from Porphyromonas gingivalis. Vaccine 2005 0.83
49 Induction of increased permeability of polarized enterocyte monolayers by enterotoxigenic Escherichia coli heat-labile enterotoxin. Am J Trop Med Hyg 2011 0.83
50 Cholera-like enterotoxins and Regulatory T cells. Toxins (Basel) 2010 0.82
51 Dynamics of forward and reverse transport by the glial glycine transporter, glyt1b. Biophys J 2005 0.82
52 Protection of mice against rotavirus challenge following intradermal DNA immunization by Biojector needle-free injection. Vaccine 2007 0.82
53 Drug-disease interaction: Crohn's disease elevates verapamil plasma concentrations but reduces response to the drug proportional to disease activity. Br J Clin Pharmacol 2011 0.79
54 Automated threshold detection for auditory brainstem responses: comparison with visual estimation in a stem cell transplantation study. BMC Neurosci 2009 0.78
55 Serum and mucosal antibody responses to inactivated polio vaccine after sublingual immunization using a thermoresponsive gel delivery system. Hum Vaccin Immunother 2014 0.78
56 Evidence for immune-mediated reduction of viral replication in Macaca nemestrina mucosally immunized with inactivated SHIV(89.6). Virology 2003 0.77
57 Mesenchymal stem cells as a novel vaccine platform. Front Cell Infect Microbiol 2012 0.76
58 Induction of serum and mucosal FIV-specific immune responses by intranasal immunization with p24Gag. Vaccine 2005 0.76
59 Unexpected modulation of recall B and T cell responses after immunization with rotavirus-like particles in the presence of LT-R192G. Toxins (Basel) 2010 0.76