PubRank

Roderich D Süssmuth

Author PubWeight™ 90.40‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep 2013 5.38
2 Structural and functional characterization of three polyketide synthase gene clusters in Bacillus amyloliquefaciens FZB 42. J Bacteriol 2006 2.29
3 The structure of salmochelins: C-glucosylated enterobactins of Salmonella enterica. Biometals 2004 1.60
4 Abyssomicin C-A polycyclic antibiotic from a marine Verrucosispora strain as an inhibitor of the p-aminobenzoic acid/tetrahydrofolate biosynthesis pathway. Angew Chem Int Ed Engl 2004 1.58
5 Plantazolicin, a novel microcin B17/streptolysin S-like natural product from Bacillus amyloliquefaciens FZB42. J Bacteriol 2010 1.47
6 A regioselective tryptophan 5-halogenase is involved in pyrroindomycin biosynthesis in Streptomyces rugosporus LL-42D005. Chem Biol 2005 1.42
7 Abyssomicins, inhibitors of the para-aminobenzoic acid pathway produced by the marine Verrucosispora strain AB-18-032. J Antibiot (Tokyo) 2004 1.32
8 Macrolactin is the polyketide biosynthesis product of the pks2 cluster of Bacillus amyloliquefaciens FZB42. J Nat Prod 2007 1.28
9 Plantazolicin A and B: structure elucidation of ribosomally synthesized thiazole/oxazole peptides from Bacillus amyloliquefaciens FZB42. Org Lett 2011 1.23
10 Insecticidal activity of 12-epi-hapalindole J isonitrile. Phytochemistry 2007 1.21
11 Heterologous expression, biosynthesis, and mutagenesis of type II lantibiotics from Bacillus licheniformis in Escherichia coli. Chem Biol 2011 1.20
12 Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis. J Biol Chem 2002 1.16
13 In vitro biosynthesis of the prepeptide of type-III lantibiotic labyrinthopeptin A2 including formation of a C-C bond as a post-translational modification. Angew Chem Int Ed Engl 2010 1.13
14 Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase. Chem Biol 2002 1.13
15 A genomic screening approach to the structure-guided identification of drug candidates from natural sources. Chembiochem 2007 1.13
16 Abyssomicins G and H and atrop-abyssomicin C from the marine Verrucosispora strain AB-18-032. J Antibiot (Tokyo) 2007 1.06
17 Oscillapeptin J, a new grazer toxin of the freshwater cyanobacterium Planktothrix rubescens. J Nat Prod 2003 1.03
18 Biosynthesis of chloro-beta-hydroxytyrosine, a nonproteinogenic amino acid of the peptidic backbone of glycopeptide antibiotics. J Bacteriol 2004 1.03
19 Cyanopeptolin 963A, a chymotrypsin inhibitor of Microcystis PCC 7806. J Nat Prod 2004 1.02
20 Labyrinthopeptins: a new class of carbacyclic lantibiotics. Angew Chem Int Ed Engl 2010 1.01
21 Planktocyclin, a cyclooctapeptide protease inhibitor produced by the freshwater cyanobacterium Planktothrix rubescens. J Nat Prod 2007 1.00
22 Action of atrop-abyssomicin C as an inhibitor of 4-amino-4-deoxychorismate synthase PabB. Angew Chem Int Ed Engl 2007 0.98
23 The final steps of bacillaene biosynthesis in Bacillus amyloliquefaciens FZB42: direct evidence for beta,gamma dehydration by a trans-acyltransferase polyketide synthase. Angew Chem Int Ed Engl 2010 0.96
24 Atacamycins A-C, 22-membered antitumor macrolactones produced by Streptomyces sp. C38. J Antibiot (Tokyo) 2011 0.95
25 Bromobalhimycin and chlorobromobalhimycins--illuminating the potential of halogenases in glycopeptide antibiotic biosyntheses. Chembiochem 2003 0.93
26 Congeneric lantibiotics from ribosomal in vivo peptide synthesis with noncanonical amino acids. Angew Chem Int Ed Engl 2011 0.93
27 Genetic analysis of the balhimycin (vancomycin-type) oxygenase genes. J Biotechnol 2006 0.93
28 Caboxamycin, a new antibiotic of the benzoxazole family produced by the deep-sea strain Streptomyces sp. NTK 937. J Antibiot (Tokyo) 2009 0.92
29 In vitro synthesis of new enniatins: probing the alpha-D-hydroxy carboxylic acid binding pocket of the multienzyme enniatin synthetase. Chembiochem 2007 0.92
30 The biosynthesis of vancomycin-type glycopeptide antibiotics--a model for oxidative side-chain cross-linking by oxygenases coupled to the action of peptide synthetases. Chembiochem 2005 0.91
31 Characterization of new class III lantibiotics--erythreapeptin, avermipeptin and griseopeptin from Saccharopolyspora erythraea, Streptomyces avermitilis and Streptomyces griseus demonstrates stepwise N-terminal leader processing. Chembiochem 2012 0.90
32 In vitro chemoenzymatic and in vivo biocatalytic syntheses of new beauvericin analogues. Chem Commun (Camb) 2012 0.90
33 Arg-Thz is a minimal substrate for the N(α),N(α)-arginyl methyltransferase involved in the biosynthesis of plantazolicin. Chem Commun (Camb) 2013 0.89
34 In vitro synthesis of new cyclodepsipeptides of the PF1022-type: probing the alpha-D-hydroxy acid tolerance of PF1022 synthetase. Chembiochem 2009 0.89
35 Mutasynthesis of glycopeptide antibiotics: variations of vancomycin's AB-ring amino acid 3,5-dihydroxyphenylglycine. J Am Chem Soc 2004 0.89
36 Proximicins A, B, and C-antitumor furan analogues of netropsin from the marine actinomycete Verrucosispora induce upregulation of p53 and the cyclin kinase inhibitor p21. Angew Chem Int Ed Engl 2008 0.88
37 Reconstituted biosynthesis of the nonribosomal macrolactone antibiotic valinomycin in Escherichia coli. ACS Synth Biol 2013 0.88
38 Deuterium labeled peptides give insights into the directionality of class III lantibiotic synthetase LabKC. J Am Chem Soc 2012 0.88
39 Recent advances in the field of bioactive tetronates. Nat Prod Rep 2014 0.88
40 The lantibiotic peptide labyrinthopeptin A1 demonstrates broad anti-HIV and anti-HSV activity with potential for microbicidal applications. PLoS One 2013 0.87
41 Chapter 18. Molecular genetic approaches to analyze glycopeptide biosynthesis. Methods Enzymol 2009 0.87
42 Leader peptide-directed processing of labyrinthopeptin A2 precursor peptide by the modifying enzyme LabKC. Biochemistry 2011 0.86
43 Total synthesis of the ribosomally synthesized linear azole-containing peptide plantazolicin A from Bacillus amyloliquefaciens. Angew Chem Int Ed Engl 2013 0.86
44 2-Amino-2-deoxyisochorismate is a key intermediate in Bacillus subtilis p-aminobenzoic acid biosynthesis. J Am Chem Soc 2009 0.86
45 Dissecting reactions of nonlinear precursor peptide processing of the class III lanthipeptide curvopeptin. J Am Chem Soc 2014 0.86
46 Biosynthetic gene cluster of the non-ribosomally synthesized cyclodepsipeptide skyllamycin: deciphering unprecedented ways of unusual hydroxylation reactions. J Am Chem Soc 2011 0.85
47 Site-directed and global incorporation of orthogonal and isostructural noncanonical amino acids into the ribosomal lasso peptide capistruin. Chembiochem 2014 0.85
48 Fluorobalhimycin--a new chapter in glycopeptide antibiotic research. Angew Chem Int Ed Engl 2002 0.85
49 Bacillus subtilis as heterologous host for the secretory production of the non-ribosomal cyclodepsipeptide enniatin. Appl Microbiol Biotechnol 2014 0.84
50 Genome mining reveals the genus Xanthomonas to be a promising reservoir for new bioactive non-ribosomally synthesized peptides. BMC Genomics 2013 0.84
51 Cytochrome p450sky interacts directly with the nonribosomal peptide synthetase to generate three amino acid precursors in skyllamycin biosynthesis. ACS Chem Biol 2013 0.84
52 The thioesterase Bhp is involved in the formation of beta-hydroxytyrosine during balhimycin biosynthesis in Amycolatopsis balhimycina. Chembiochem 2010 0.84
53 The structure of a transient complex of a nonribosomal peptide synthetase and a cytochrome P450 monooxygenase. Angew Chem Int Ed Engl 2014 0.84
54 Paenilamicin: structure and biosynthesis of a hybrid nonribosomal peptide/polyketide antibiotic from the bee pathogen Paenibacillus larvae. Angew Chem Int Ed Engl 2014 0.83
55 Engineering the heterologous expression of lanthipeptides in Escherichia coli by multigene assembly. Appl Microbiol Biotechnol 2015 0.83
56 Thioamides in nature: in search of secondary metabolites in anaerobic microorganisms. Chembiochem 2010 0.83
57 Elaiomycins B and C, novel alkylhydrazides produced by Streptomyces sp. BK 190. J Antibiot (Tokyo) 2011 0.82
58 Structure elucidation of auxofuran, a metabolite involved in stimulating growth of fly agaric, produced by the mycorrhiza helper bacterium Streptomyces AcH 505. J Antibiot (Tokyo) 2006 0.82
59 Two new aurachins from Rhodococcus sp. Acta 2259. J Antibiot (Tokyo) 2010 0.82
60 Feglymycin is an inhibitor of the enzymes MurA and MurC of the peptidoglycan biosynthesis pathway. Chembiochem 2011 0.82
61 Involvement and unusual substrate specificity of a prolyl oligopeptidase in class III lanthipeptide maturation. J Am Chem Soc 2013 0.81
62 Nataxazole, a new benzoxazole derivative with antitumor activity produced by Streptomyces sp. Tü 6176. J Antibiot (Tokyo) 2008 0.81
63 The structures of fluostatins C, D and E, novel members of the fluostatin family. J Antibiot (Tokyo) 2006 0.81
64 Structural aspects of phenylglycines, their biosynthesis and occurrence in peptide natural products. Nat Prod Rep 2015 0.81
65 Elucidation of sevadicin, a novel non-ribosomal peptide secondary metabolite produced by the honey bee pathogenic bacterium Paenibacillus larvae. Environ Microbiol 2014 0.81
66 Langkolide, a 32-membered macrolactone antibiotic produced by Streptomyces sp. Acta 3062. J Nat Prod 2012 0.80
67 Two heterologously expressed Planobispora rosea proteins cooperatively induce Streptomyces lividans thiostrepton uptake and storage from the extracellular medium. Microb Cell Fact 2010 0.80
68 Feglymycin, a unique natural bacterial antibiotic peptide, inhibits HIV entry by targeting the viral envelope protein gp120. Virology 2012 0.80
69 Functional characterization of the recombinant N-methyltransferase domain from the multienzyme enniatin synthetase. Chembiochem 2007 0.80
70 Involvement of secondary metabolites in the pathogenesis of the American foulbrood of honey bees caused by Paenibacillus larvae. Nat Prod Rep 2015 0.80
71 Curvopeptin: a new lanthionine-containing class III lantibiotic and its co-substrate promiscuous synthetase. Chembiochem 2012 0.80
72 Heterologous expression and engineering studies of labyrinthopeptins, class III lantibiotics from Actinomadura namibiensis. Chem Biol 2013 0.80
73 Fluostatins C-E, novel members of the fluostatin family produced by Streptomyces strain Acta 1383. J Antibiot (Tokyo) 2006 0.80
74 Abyssomicin biosynthesis: formation of an unusual polyketide, antibiotic-feeding studies and genetic analysis. Chembiochem 2011 0.80
75 The E. coli siderophores enterobactin and salmochelin form six-coordinate silicon complexes at physiological pH. Angew Chem Int Ed Engl 2011 0.80
76 Aranciamycin anhydride, a new anthracycline-type antibiotic isolated from Streptomyces sp. Tü 6384(*). J Antibiot (Tokyo) 2010 0.80
77 Albidopyrone, a new alpha-pyrone-containing metabolite from marine-derived Streptomyces sp. NTK 227. J Antibiot (Tokyo) 2009 0.79
78 Biological effects of paenilamicin, a secondary metabolite antibiotic produced by the honey bee pathogenic bacterium Paenibacillus larvae. Microbiologyopen 2014 0.79
79 Gombapyrones, new alpha-pyrone metabolites produced by Streptomyces griseoruber Acta 3662. J Antibiot (Tokyo) 2009 0.79
80 Alanine scan of the peptide antibiotic feglymycin: assessment of amino acid side chains contributing to antimicrobial activity. Chembiochem 2013 0.79
81 Elloxazinones A and B, New Aminophenoxazinones from Streptomyces griseus Acta 2871. J Antibiot (Tokyo) 2007 0.78
82 Nocardichelins A and B, siderophores from Nocardia strain acta 3026. J Nat Prod 2007 0.78
83 Piceamycin and its N-acetylcysteine adduct is produced by Streptomyces sp. GB 4-2. J Antibiot (Tokyo) 2009 0.78
84 Lichenicidin biosynthesis in Escherichia coli: licFGEHI immunity genes are not essential for lantibiotic production or self-protection. Appl Environ Microbiol 2011 0.78
85 Total synthesis of the antiviral peptide antibiotic feglymycin. Angew Chem Int Ed Engl 2009 0.78
86 Module extension of a non-ribosomal peptide synthetase of the glycopeptide antibiotic balhimycin produced by Amycolatopsis balhimycina. Chembiochem 2008 0.78
87 Champacyclin, a new cyclic octapeptide from Streptomyces strain C42 isolated from the Baltic Sea. Mar Drugs 2013 0.77
88 Identification of the amino acid labionin and its desulfurised derivative in the type-III lantibiotic LabA2 by means of GC/MS. Chem Commun (Camb) 2011 0.77
89 Total synthesis of albicidin: a lead structure from Xanthomonas albilineans for potent antibacterial gyrase inhibitors. Angew Chem Int Ed Engl 2014 0.77
90 Total synthesis of proximicin A-C and synthesis of new furan-based DNA binding agents. Org Lett 2009 0.77
91 Langkocyclines: novel angucycline antibiotics from Streptomyces sp. Acta 3034(*). J Antibiot (Tokyo) 2013 0.77
92 Elaiomycins K and L, new azoxy antibiotics from Streptomyces sp. Tü 6399*. J Antibiot (Tokyo) 2012 0.76
93 Benzoxacystol, a benzoxazine-type enzyme inhibitor from the deep-sea strain Streptomyces sp. NTK 935. J Antibiot (Tokyo) 2011 0.76
94 Synthetic studies toward labionin, a new α,α-disubstituted amino acid from type III lantibiotic labyrinthopeptin A2. J Pept Sci 2011 0.75
95 Application of a rapid and integrated analysis system (RIAS) as a high-throughput processing tool for in vitro ADME samples by liquid chromatography/tandem mass spectrometry. J Biomol Screen 2011 0.75
96 Highlighting the role of the chlorine substituents in the glycopeptide antibiotic balhimycin for chiral recognition in capillary electrophoresis. Electrophoresis 2006 0.75
97 Evaluation of balhimycin as a chiral selector for enantioresolution by capillary electrophoresis. Electrophoresis 2004 0.75
98 Elimination reactions of esters in the biosynthesis of polyketides and ribosomal peptides. Angew Chem Int Ed Engl 2013 0.75
99 Bendigoles A approximately C, new steroids from Gordonia australis Acta 2299. J Antibiot (Tokyo) 2008 0.75
100 Lipocarbazoles, secondary metabolites from Tsukamurella pseudospumae Acta 1857 with antioxidative activity. J Nat Prod 2009 0.75
101 Synthesis and evaluation of a netropsin-proximicin-hybrid library for DNA binding and cytotoxicity. Bioorg Med Chem Lett 2009 0.75
102 Silvalactam, a 24-membered macrolactam antibiotic produced by Streptomyces sp. Tü 6392*. J Antibiot (Tokyo) 2012 0.75
103 Elucidation of sevadicin, a novel non-ribosomal peptide secondary metabolite produced by the honey bee pathogenic bacterium Paenibacillus larvae. Environ Microbiol 2014 0.75
104 Conformational investigation of antibiotic proximicin by X-ray structure analysis and quantum studies suggest a stretched conformation of this type of γ-peptide. Bioorg Med Chem 2013 0.75
105 Elaiomycins B and C: alkylhydrazide antibiotics from Streptomyces sp. BK 190. Org Lett 2011 0.75
106 Warkmycin, a novel angucycline antibiotic produced by Streptomyces sp. Acta 2930*. J Antibiot (Tokyo) 2013 0.75
107 Impact of domestication in the production of the class II lanthipeptide lichenicidin by Bacillus licheniformis I89. Curr Microbiol 2014 0.75
108 Biotransformation of the fungal phytotoxin fomannoxin by soil streptomycetes. J Chem Ecol 2013 0.75
109 Highlighting the possible secondary interactions in the role of balhimycin and its analogues for enantiorecognition in capillary electrophoresis. J Chromatogr A 2009 0.75
110 Stereochemistry and conformation of skyllamycin, a non-ribosomally synthesized peptide from Streptomyces sp. Acta 2897. Chemistry 2014 0.75
111 A mechanistic study of enantiomeric separation with vancomycin and balhimycin as chiral selectors by capillary electrophoresis. Dimerization and enantioselectivity. Anal Chem 2004 0.75