PubRank

Jörn Piel

Author PubWeight™ 51.58‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection. Nat Biotechnol 2008 2.35
2 Defensive bacteriome symbiont with a drastically reduced genome. Curr Biol 2013 2.34
3 Structural and functional characterization of three polyketide synthase gene clusters in Bacillus amyloliquefaciens FZB 42. J Bacteriol 2006 2.29
4 Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides. Science 2012 1.84
5 Genomic insights into the marine sponge microbiome. Nat Rev Microbiol 2012 1.83
6 Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting. Nat Chem Biol 2009 1.75
7 Single-cell genomics reveals the lifestyle of Poribacteria, a candidate phylum symbiotically associated with marine sponges. ISME J 2010 1.66
8 Insights into the biosynthesis of hormaomycin, an exceptionally complex bacterial signaling metabolite. Chem Biol 2011 1.61
9 Polyketide proofreading by an acyltransferase-like enzyme. Chem Biol 2012 1.57
10 A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A. Chem Biol 2002 1.16
11 Biosynthesis of the antibiotic bacillaene, the product of a giant polyketide synthase complex of the trans-AT family. Angew Chem Int Ed Engl 2007 1.10
12 Polyketide synthases of bacterial symbionts in sponges--evolution-based applications in natural products research. Phytochemistry 2009 1.04
13 Metagenomic natural product discovery in lichen provides evidence for a family of biosynthetic pathways in diverse symbioses. Proc Natl Acad Sci U S A 2013 1.04
14 Metagenomic approaches for exploiting uncultivated bacteria as a resource for novel biosynthetic enzymology. Chem Biol 2013 1.03
15 The genus Pseudovibrio contains metabolically versatile bacteria adapted for symbiosis. Environ Microbiol 2013 1.02
16 Supramolecular templating in kirromycin biosynthesis: the acyltransferase KirCII loads ethylmalonyl-CoA extender onto a specific ACP of the trans-AT PKS. Chem Biol 2011 1.02
17 Phylum-wide comparative genomics unravel the diversity of secondary metabolism in Cyanobacteria. BMC Genomics 2014 1.02
18 Biosynthesis of the myxobacterial antibiotic corallopyronin A. Chembiochem 2010 1.01
19 Widespread occurrence and genomic context of unusually small polyketide synthase genes in microbial consortia associated with marine sponges. Appl Environ Microbiol 2007 1.00
20 Linking chemical and microbial diversity in marine sponges: possible role for poribacteria as producers of methyl-branched fatty acids. Chembiochem 2010 0.99
21 Soaking it up: the complex lives of marine sponges and their microbial associates. ISME J 2007 0.98
22 Feeding of [5,5-2H(2)]-1-desoxy-D-xylulose and [4,4,6,6,6-2H(5)]-mevalolactone to a geosmin-producing Streptomyces sp. and Fossombronia pusilla. Phytochemistry 2002 0.97
23 Pederin-type pathways of uncultivated bacterial symbionts: analysis of o-methyltransferases and generation of a biosynthetic hybrid. J Am Chem Soc 2009 0.96
24 Plant-like biosynthetic pathways in bacteria: from benzoic acid to chalcone. J Nat Prod 2002 0.96
25 The final steps of bacillaene biosynthesis in Bacillus amyloliquefaciens FZB42: direct evidence for beta,gamma dehydration by a trans-acyltransferase polyketide synthase. Angew Chem Int Ed Engl 2010 0.96
26 Biosynthesis of pentangular polyphenols: deductions from the benastatin and griseorhodin pathways. J Am Chem Soc 2007 0.95
27 Genome mining reveals trans-AT polyketide synthase directed antibiotic biosynthesis in the bacterial phylum bacteroidetes. Chembiochem 2010 0.95
28 Rapid isolation of rare clones from highly complex DNA libraries by PCR analysis of liquid gel pools. J Microbiol Methods 2006 0.95
29 An enzymatic domain for the formation of cyclic ethers in complex polyketides. Angew Chem Int Ed Engl 2013 0.94
30 Substrate specificity in ketosynthase domains from trans-AT polyketide synthases. Angew Chem Int Ed Engl 2012 0.93
31 A novel Dps-type protein from insect gut bacteria catalyses hydrolysis and synthesis of N-acyl amino acids. Environ Microbiol 2007 0.92
32 Analysis of the sorangicin gene cluster reinforces the utility of a combined phylogenetic/retrobiosynthetic analysis for deciphering natural product assembly by trans-AT PKS. Chembiochem 2010 0.90
33 Radical S-adenosyl methionine epimerases: regioselective introduction of diverse D-amino acid patterns into peptide natural products. Angew Chem Int Ed Engl 2014 0.90
34 The Catalytic Diversity of Multimodular Polyketide Synthases: Natural Product Biosynthesis Beyond Textbook Assembly Rules. Top Curr Chem 2011 0.89
35 Expression of the lantibiotic mersacidin in Bacillus amyloliquefaciens FZB42. PLoS One 2011 0.86
36 Habitat-specific type I polyketide synthases in soils and street sediments. J Ind Microbiol Biotechnol 2013 0.86
37 Polyketide genes in the marine sponge Plakortis simplex: a new group of mono-modular type I polyketide synthases from sponge symbionts. Environ Microbiol Rep 2013 0.86
38 Cleavage of four carbon-carbon bonds during biosynthesis of the griseorhodin a spiroketal pharmacophore. J Am Chem Soc 2009 0.85
39 Acyl-chain elongation drives ketosynthase substrate selectivity in trans-acyltransferase polyketide synthases. Angew Chem Int Ed Engl 2014 0.84
40 Metagenomic approaches to identify and isolate bioactive natural products from microbiota of marine sponges. Methods Mol Biol 2010 0.83
41 Reciprocal cross talk between fatty acid and antibiotic biosynthesis in a nematode symbiont. Angew Chem Int Ed Engl 2012 0.83
42 Regio- and stereoselective oxidative phenol coupling in Aspergillus niger. Angew Chem Int Ed Engl 2012 0.82
43 Manipulation of regulatory genes reveals complexity and fidelity in hormaomycin biosynthesis. Chem Biol 2013 0.80
44 Defense in the aeolidoidean genus Phyllodesmium (Gastropoda). J Chem Ecol 2014 0.78
45 Natural products via enzymatic reactions. Preface. Top Curr Chem 2010 0.78
46 Phenalenones: insight into the biosynthesis of polyketides from the marine alga-derived fungus Coniothyrium cereale. Org Biomol Chem 2015 0.77
47 Biosynthesis of phenylnannolone A, a multidrug resistance reversal agent from the halotolerant myxobacterium Nannocystis pusilla B150. Chembiochem 2014 0.77
48 Biosynthetic origin of the antibiotic cyclocarbamate brabantamide A (SB-253514) in plant-associated Pseudomonas. Chembiochem 2014 0.76
49 Use of a halogenase of hormaomycin biosynthesis for formation of new clorobiocin analogues with 5-chloropyrrole moieties. Chembiochem 2008 0.75
50 Acyl hydrolases from trans-AT polyketide synthases target acetyl units on acyl carrier proteins. Chem Commun (Camb) 2016 0.75