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1
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TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
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Biochem Biophys Res Commun
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2006
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10.69
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2
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Gene expression in fixed tissues and outcome in hepatocellular carcinoma.
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N Engl J Med
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2008
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9.20
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3
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Long-term entecavir treatment reduces hepatocellular carcinoma incidence in patients with hepatitis B virus infection.
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Hepatology
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2013
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5.03
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4
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Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma.
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Cancer Res
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2009
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3.77
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5
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Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders.
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Hepatology
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2012
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3.54
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6
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Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin.
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Hepatology
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2010
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3.00
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7
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Daclatasvir plus asunaprevir for chronic HCV genotype 1b infection.
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Hepatology
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2014
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2.83
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8
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Effect of type 2 diabetes on risk for malignancies includes hepatocellular carcinoma in chronic hepatitis C.
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Hepatology
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2013
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2.36
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9
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Characterization of virologic escape in hepatitis C virus genotype 1b patients treated with the direct-acting antivirals daclatasvir and asunaprevir.
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J Hepatol
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2012
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2.34
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10
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Dual oral therapy with daclatasvir and asunaprevir for patients with HCV genotype 1b infection and limited treatment options.
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J Hepatol
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2012
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2.14
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11
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Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers.
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Nat Genet
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2011
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2.09
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12
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Predictive factors of early and sustained responses to peginterferon plus ribavirin combination therapy in Japanese patients infected with hepatitis C virus genotype 1b: amino acid substitutions in the core region and low-density lipoprotein cholesterol levels.
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J Hepatol
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2006
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2.09
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13
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Sustained virological response reduces incidence of onset of type 2 diabetes in chronic hepatitis C.
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Hepatology
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2009
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1.83
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14
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Low risk of adefovir resistance in lamivudine-resistant chronic hepatitis B patients treated with adefovir plus lamivudine combination therapy: two-year follow-up.
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J Hepatol
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2008
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1.76
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15
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Association of amino acid substitution pattern in core protein of hepatitis C virus genotype 1b high viral load and non-virological response to interferon-ribavirin combination therapy.
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Intervirology
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2005
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1.71
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16
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Poor response to pegylated interferon and ribavirin in older women infected with hepatitis C virus of genotype 1b in high viral loads.
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Dig Dis Sci
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2008
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1.67
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17
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Factors contributing to ribavirin dose reduction due to anemia during interferon alfa2b and ribavirin combination therapy for chronic hepatitis C.
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J Gastroenterol
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2004
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1.66
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18
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Diabetes mellitus worsens the recurrence rate after potentially curative therapy in patients with hepatocellular carcinoma associated with nonviral hepatitis.
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J Gastroenterol Hepatol
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2008
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1.59
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19
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Long-term continuous entecavir therapy in nucleos(t)ide-naïve chronic hepatitis B patients.
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J Hepatol
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2012
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1.53
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20
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Infection with hepatitis B virus genotype A in Tokyo, Japan during 1976 through 2001.
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J Gastroenterol
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2004
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1.46
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21
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Occurrence of T cells in the brain of Alzheimer's disease and other neurological diseases.
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J Neuroimmunol
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2002
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1.45
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22
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Efficacy of prolonged interferon therapy for patients with chronic hepatitis C with HCV-genotype 1b and high virus load.
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J Gastroenterol
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2003
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1.45
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23
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Global democratic consensus on neuropathological disease criteria.
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Lancet Neurol
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2002
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1.44
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24
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Interferon for treatment of breakthrough infection with hepatitis B virus mutants developing during long-term lamivudine therapy.
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J Gastroenterol
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2002
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1.43
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25
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Efficacy of 6-month interferon therapy in chronic hepatitis B virus infection in Japan.
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J Gastroenterol
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2004
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1.42
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26
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Adequate timing of ribavirin reduction in patients with hemolysis during combination therapy of interferon and ribavirin for chronic hepatitis C.
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J Gastroenterol
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2004
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1.41
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27
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Prevalence of hepatitis C virus variants resistant to NS3 protease inhibitors or the NS5A inhibitor (BMS-790052) in hepatitis patients with genotype 1b.
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J Clin Virol
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2012
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1.35
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28
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Lamivudine monotherapy for spontaneous severe acute exacerbation of chronic hepatitis B.
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J Gastroenterol Hepatol
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2005
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1.26
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29
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Large-scale long-term follow-up study of Japanese patients with non-alcoholic Fatty liver disease for the onset of hepatocellular carcinoma.
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Am J Gastroenterol
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2011
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1.21
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30
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Amino acid substitutions in the hepatitis C virus core region are the important predictor of hepatocarcinogenesis.
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Hepatology
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2007
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1.16
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31
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Identification of amino-terminally cleaved tau fragments that distinguish progressive supranuclear palsy from corticobasal degeneration.
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Ann Neurol
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2004
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1.13
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32
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Increased expression of neuronal apolipoprotein E in human brain with cerebral infarction.
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Stroke
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2003
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1.13
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33
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Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.
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Hepatology
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2011
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1.12
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34
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Expression of BRI, the normal precursor of the amyloid protein of familial British dementia, in human brain.
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Acta Neuropathol
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2003
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1.10
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35
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Predictors of viral kinetics to peginterferon plus ribavirin combination therapy in Japanese patients infected with hepatitis C virus genotype 1b.
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J Med Virol
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2007
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1.10
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36
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Enhanced expression of aquaporin 4 in human brain with infarction.
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Acta Neuropathol
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2003
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1.09
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37
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Guideline on the use of new anticancer drugs for the treatment of Hepatocellular Carcinoma 2010 update.
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Hepatol Res
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2012
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1.07
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38
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Clinical characteristics of patients infected with hepatitis B virus genotypes A, B, and C.
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J Gastroenterol
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2002
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1.06
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39
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The influence of hepatitis B virus genotype on the development of lamivudine resistance during long-term treatment.
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J Hepatol
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2003
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1.05
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40
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Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy.
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Neuropathology
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2010
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1.04
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41
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Predictive factors of virological non-response to interferon-ribavirin combination therapy for patients infected with hepatitis C virus of genotype 1b and high viral load.
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J Med Virol
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2006
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1.04
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42
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14-3-3 proteins and zeta isoform containing neurofibrillary tangles in patients with Alzheimer's disease.
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Acta Neuropathol
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2004
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1.01
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43
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Viral elimination reduces incidence of malignant lymphoma in patients with hepatitis C.
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Am J Med
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2007
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1.00
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44
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Renal dysfunction and hypophosphatemia during long-term lamivudine plus adefovir dipivoxil therapy in patients with chronic hepatitis B.
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J Gastroenterol
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2013
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1.00
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45
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Immunohistochemical study of brain-derived neurotrophic factor and its receptor, TrkB, in the hippocampal formation of schizophrenic brains.
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Prog Neuropsychopharmacol Biol Psychiatry
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2003
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1.00
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46
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Viral genotypes and response to interferon in patients with acute prolonged hepatitis B virus infection of adulthood in Japan.
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J Med Virol
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2002
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0.99
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47
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Prediction of response to pegylated interferon and ribavirin in hepatitis C by polymorphisms in the viral core protein and very early dynamics of viremia.
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Intervirology
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2007
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0.99
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48
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Sustained virological response in a patient with chronic hepatitis C treated by monotherapy with the NS3-4A protease inhibitor telaprevir.
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J Clin Virol
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2009
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0.99
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49
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High serum des-gamma-carboxy prothrombin level predicts poor prognosis after radiofrequency ablation of hepatocellular carcinoma.
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Cancer
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2009
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0.99
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50
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Peretinoin after curative therapy of hepatitis C-related hepatocellular carcinoma: a randomized double-blind placebo-controlled study.
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J Gastroenterol
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2014
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0.98
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51
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Persistence of acute infection with hepatitis B virus genotype A and treatment in Japan.
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J Med Virol
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2005
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0.98
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52
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Prolonged-interferon therapy reduces hepatocarcinogenesis in aged-patients with chronic hepatitis C.
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J Med Virol
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2007
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0.98
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53
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A matched case-controlled study of 48 and 72 weeks of peginterferon plus ribavirin combination therapy in patients infected with HCV genotype 1b in Japan: amino acid substitutions in HCV core region as predictor of sustained virological response.
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J Med Virol
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2009
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0.97
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54
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Dysplastic nodules frequently develop into hepatocellular carcinoma in patients with chronic viral hepatitis and cirrhosis.
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Cancer
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2006
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0.97
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55
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YMDD mutants in patients with chronic hepatitis B before treatment are not selected by lamivudine.
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J Med Virol
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2004
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0.97
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56
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The influence of histological differentiation grade on the outcome of liver resection for hepatocellular carcinomas 2 cm or smaller in size.
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World J Surg
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2015
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0.96
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57
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Activation of vascular endothelial cells and perivascular cells by systemic inflammation-an immunohistochemical study of postmortem human brain tissues.
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Acta Neuropathol
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2004
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0.96
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58
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Natural history of compensated cirrhosis in the Child-Pugh class A compared between 490 patients with hepatitis C and 167 with B virus infections.
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J Med Virol
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2006
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0.96
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59
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Virological response and hepatocarcinogenesis in lamivudine-resistant hepatitis B virus genotype C patients treated with lamivudine plus adefovir dipivoxil.
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Intervirology
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2009
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0.96
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60
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Hepatocarcinogenesis following HCV RNA eradication by interferon in chronic hepatitis patients.
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Intern Med
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2008
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0.96
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61
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An open pilot study exploring the efficacy of fluvastatin, pegylated interferon and ribavirin in patients with hepatitis C virus genotype 1b in high viral loads.
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Intervirology
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2009
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0.95
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62
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Low rate of YMDD motif mutations in polymerase gene of hepatitis B virus in chronically infected patients not treated with lamivudine.
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J Gastroenterol
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2004
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0.95
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63
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Long-term outcome after interferon therapy in elderly patients with chronic hepatitis C.
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Intervirology
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2007
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0.94
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64
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Determinants of response to triple therapy of telaprevir, peginterferon, and ribavirin in previous non-responders infected with HCV genotype 1.
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J Med Virol
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2012
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0.94
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65
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Emergence of telaprevir-resistant variants detected by ultra-deep sequencing after triple therapy in patients infected with HCV genotype 1.
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J Med Virol
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2013
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0.94
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66
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Mutations of polymerase, precore and core promoter gene in hepatitis B virus during 5-year lamivudine therapy.
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J Hepatol
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2002
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0.94
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67
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Highly sensitive AFP-L3% assay is useful for predicting recurrence of hepatocellular carcinoma after curative treatment pre- and postoperatively.
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Hepatol Res
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2011
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0.93
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68
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Virus clearance reduces bone fracture in postmenopausal women with osteoporosis and chronic liver disease caused by hepatitis C virus.
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J Med Virol
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2010
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0.93
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69
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Early viral kinetics and treatment outcome in combination of high-dose interferon induction vs. pegylated interferon plus ribavirin for naive patients infected with hepatitis C virus of genotype 1b and high viral load.
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J Med Virol
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2005
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0.92
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70
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Complicated relationships of amino acid substitution in hepatitis C virus core region and IL28B genotype influencing hepatocarcinogenesis.
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Hepatology
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2012
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0.92
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71
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Clinical and virological characteristics of untreated patients with chronic hepatitis C who develop serum alanine aminotransferase flare-up.
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J Med Virol
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2005
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0.91
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72
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Change of hepatitis B virus genotypes in acute and chronic infections in Japan.
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J Med Virol
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2008
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0.91
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73
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Long-term outcome after hepatitis B surface antigen seroclearance in patients with chronic hepatitis B.
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Am J Med
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2006
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0.91
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74
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Development of HCC in patients receiving adefovir dipivoxil for lamivudine-resistant hepatitis B virus mutants.
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Hepatol Res
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2009
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0.91
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75
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Association of two polymorphisms of the IL28B gene with viral factors and treatment response in 1,518 patients infected with hepatitis C virus.
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J Gastroenterol
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2012
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0.91
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76
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Prediction of treatment efficacy and telaprevir-resistant variants after triple therapy in patients infected with hepatitis C virus genotype 1.
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J Clin Microbiol
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2013
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0.91
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77
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Protective effects of lactoferrin against intestinal mucosal damage induced by lipopolysaccharide in human intestinal Caco-2 cells.
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Yakugaku Zasshi
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2008
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0.90
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78
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A randomized trial of daclatasvir with peginterferon alfa-2b and ribavirin for HCV genotype 1 infection.
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Antivir Ther
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2014
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0.90
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79
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Hepatocellular carcinoma in noncirrhotic young adult patients with chronic hepatitis B viral infection.
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J Gastroenterol
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2004
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0.90
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80
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Association of amino acid substitution pattern in core protein of hepatitis C virus genotype 2a high viral load and virological response to interferon-ribavirin combination therapy.
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Intervirology
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2009
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0.90
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81
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Efficacy of interferon monotherapy to 394 consecutive naive cases infected with hepatitis C virus genotype 2a in Japan: therapy efficacy as consequence of tripartite interaction of viral, host and interferon treatment-related factors.
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J Hepatol
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2002
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0.90
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82
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Amino acid substitutions in the hepatitis C virus core region of genotype 1b affect very early viral dynamics during treatment with telaprevir, peginterferon, and ribavirin.
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J Med Virol
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2010
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0.90
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83
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Stepwise hook extension technique for radiofrequency ablation therapy of hepatocellular carcinoma.
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Oncology
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2002
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84
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Inhibitory effect of branched-chain amino acid granules on progression of compensated liver cirrhosis due to hepatitis C virus.
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J Gastroenterol
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0.89
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85
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Amino acid substitutions in hepatitis C virus core region predict hepatocarcinogenesis following eradication of HCV RNA by antiviral therapy.
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J Med Virol
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2011
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0.89
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86
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Clinical effectiveness of bipolar radiofrequency ablation for small liver cancers.
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J Gastroenterol
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2012
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0.89
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87
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Amino acid substitutions in the hepatitis C virus core region of genotype 1b are the important predictor of severe insulin resistance in patients without cirrhosis and diabetes mellitus.
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J Med Virol
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2009
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0.89
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88
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Virological and biochemical relapse according to YMDD motif mutant type during long-term lamivudine monotherapy.
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J Med Virol
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2003
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0.89
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89
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Two distinct subgroups of senile dementia of Alzheimer type: quantitative study of neurofibrillary tangles.
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Neuropathology
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2003
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0.88
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90
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Multivariate analysis of risk factors for the development of type 2 diabetes in nonalcoholic fatty liver disease.
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J Gastroenterol
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0.88
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91
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Glial involvement in diffuse Lewy body disease.
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Acta Neuropathol
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2002
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0.88
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92
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Long-term follow-up of interferon monotherapy in 454 consecutive naive patients infected with hepatitis C virus: multi-course interferon therapy may reduce the risk of hepatocellular carcinoma and increase survival.
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Scand J Gastroenterol
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2005
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0.88
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93
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Selection of a virus strain resistant to entecavir in a nucleoside-naive patient with hepatitis B of genotype H.
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J Clin Virol
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0.88
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94
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Neuronal and glial inclusions in frontotemporal dementia with or without motor neuron disease are immunopositive for p62.
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Neurosci Lett
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2003
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0.88
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95
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Amino acid substitution in HCV core region and genetic variation near the IL28B gene affect viral dynamics during telaprevir, peginterferon and ribavirin treatment.
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Intervirology
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2012
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0.88
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96
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Long-term efficacy of interferon therapy in patients with chronic hepatitis B virus infection in Japan.
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J Gastroenterol
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0.87
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97
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Determinants of serum ALT normalization after phlebotomy in patients with chronic hepatitis C infection.
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0.87
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98
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Efficacy of lamivudine therapy and factors associated with emergence of resistance in chronic hepatitis B virus infection in Japan.
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0.87
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Diabetes mellitus increases the risk of hepatocarcinogenesis in patients with alcoholic cirrhosis: A preliminary report.
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Hepatol Res
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2007
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0.86
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100
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Rapid loss of hepatitis C virus genotype 1b from serum in patients receiving a triple treatment with telaprevir (MP-424), pegylated interferon and ribavirin for 12 weeks.
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Hepatol Res
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2009
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0.86
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101
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Sporadic amyotrophic lateral sclerosis of long duration mimicking spinal progressive muscular atrophy exists: additional autopsy case with a clinical course of 19 years.
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Neuropathology
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2004
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0.86
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102
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Transcatheter arterial chemotherapy using miriplatin-lipiodol suspension with or without embolization for unresectable hepatocellular carcinoma.
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Jpn J Clin Oncol
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103
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Changes of the peptide YY levels in the intestinal tissue of rats with experimental colitis following oral administration of mesalazine and prednisolone.
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0.86
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104
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Predictive factors of advanced recurrence after curative resection of small hepatocellular carcinoma.
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Sporadic amyotrophic lateral sclerosis with circumscribed temporal atrophy: a report of an autopsy case without dementia and with ubiquitinated intraneuronal inclusions.
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107
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Interferon lowers tumor recurrence rate after surgical resection or ablation of hepatocellular carcinoma: a pilot study of patients with hepatitis B virus-related cirrhosis.
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Determinants of the clinical outcome of patients with severe acute exacerbation of chronic hepatitis B virus infection.
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Difference in malignancies of chronic liver disease due to non-alcoholic fatty liver disease or hepatitis C in Japanese elderly patients.
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Hepatol Res
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Effectiveness of combination therapy of splenectomy and long-term interferon in patients with hepatitis C virus-related cirrhosis and thrombocytopenia.
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Pick body disease and Pick syndrome.
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Substitution of amino acid 70 in the hepatitis C virus core region of genotype 1b is an important predictor of elevated alpha-fetoprotein in patients without hepatocellular carcinoma.
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An autopsy case of Creutzfeldt-Jakob disease with a V180I mutation of the PrP gene and Alzheimer-type pathology.
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Long-term follow-up of HBeAg-positive young adult Japanese patients treated with corticosteroid withdrawal therapy for chronic hepatitis B.
|
Intervirology
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2006
|
0.75
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263
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[An autopsy case of senile dementia with pathological features of Parkinson's disease].
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No To Shinkei
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2004
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0.75
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264
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[A questionnaire survey for pharmacists participating in a home medical care training workshop].
|
Gan To Kagaku Ryoho
|
2012
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0.75
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265
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Potential impact of joint association of alanine aminotransferase and gamma-glutamyltransferase on insulin resistance in Japan: The Toranomon Hospital Health Management Center Study 19 (TOPICS 19).
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Hepatol Res
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2014
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0.75
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266
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Randomized controlled trial of a new procedure of radiofrequency ablation using an expandable needle for hepatocellular carcinoma.
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Hepatol Res
|
2013
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0.75
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|
267
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Development of hepatocellular carcinoma in elderly patients with chronic hepatitis C with or without elevated aspartate and alanine aminotransferase levels.
|
Scand J Gastroenterol
|
2009
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0.75
|
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268
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Outcome of All-Oral Direct-Acting Antiviral Regimens on the Rate of Development of Hepatocellular Carcinoma in Patients with Hepatitis C Virus Genotype 1-Related Chronic Liver Disease.
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Oncology
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2017
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0.75
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269
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Clinicopathological improvement of non-alcoholic steatohepatitis associated with weight loss during a 14-year follow-up period.
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Liver Int
|
2007
|
0.75
|
|
270
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[Comparison of antiemetic efficacy of 5-HT3 receptor antagonists in orthopedics cancer patients receiving high-dose chemotherapy].
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Gan To Kagaku Ryoho
|
2007
|
0.75
|
|
271
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Serum KL-6 level is elevated in chronic hepatitis C patients with combination therapy of pegylated interferon and ribavirin.
|
Intern Med
|
2007
|
0.75
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|
272
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[Organic cause of emotional depression].
|
Seishin Shinkeigaku Zasshi
|
2007
|
0.75
|
|
273
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[Predisposition to emotional disorders].
|
Seishin Shinkeigaku Zasshi
|
2007
|
0.75
|
|
274
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Terahertz absorption spectra of original and generic ceftazidime.
|
Anal Sci
|
2009
|
0.75
|
|
275
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Favorable efficacy of long-term lamivudine therapy in patients with chronic hepatitis B: an 8-year follow-up study.
|
J Med Virol
|
2005
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0.75
|
|
276
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Pick's disease with Pick bodies: an unusual autopsy case showing degeneration of the pontine nucleus, dentate nucleus, Clarke's column, and lower motor neuron.
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Neuropathology
|
2007
|
0.75
|
|
277
|
Interferon-alpha for reinfection with hepatitis C virus in two patients with chronic hepatitis C who had responded to previous therapies.
|
Dig Dis Sci
|
2003
|
0.75
|
|
278
|
Changes of intestinal mucosal and plasma PYY in a diarrhea model rat and influence of loperamide as the treatment agent for diarrhea.
|
Yakugaku Zasshi
|
2008
|
0.75
|
|
279
|
Lipiodol and dye at the site of ablation decreases during RFA.
|
Intervirology
|
2009
|
0.75
|
|
280
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Adefovir dipivoxil for treatment of breakthrough hepatitis caused by lamivudine-resistant mutants of hepatitis B virus.
|
Intervirology
|
2004
|
0.75
|
|
281
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Natural histories of hepatitis C virus infection in men and women simulated by the Markov model.
|
J Med Virol
|
2003
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0.75
|
|
282
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Association of IL28B genotype and viral response of hepatitis C virus genotype 2 to interferon plus ribavirin combination therapy.
|
J Med Virol
|
2012
|
0.75
|
|
283
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Interferon monotherapy for patients with chronic hepatitis C and normal serum aminotransferase levels at commencement of treatment.
|
J Gastroenterol
|
2004
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0.75
|
|
284
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Evolution of simeprevir-resistant variants in virological non-responders infected with HCV genotype 1b.
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J Med Virol
|
2015
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0.75
|
|
285
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[Anti-viral therapy of type B chronic hepatitis. 1. Selection of evidence-based therapeutic policy].
|
Nihon Naika Gakkai Zasshi
|
2008
|
0.75
|
|
286
|
The efficacy of 24-week interferon monotherapy for type C liver cirrhosis in Japanese patients with genotype 1b and low virus load.
|
Intervirology
|
2008
|
0.75
|
|
287
|
New ablation procedure for a radiofrequency liver tissue coagulation system using an expandable needle.
|
Liver Int
|
2007
|
0.75
|
|
288
|
Comparison of interferon and lamivudine treatment in Japanese patients with HBeAg positive chronic hepatitis B.
|
J Med Virol
|
2007
|
0.75
|
|
289
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[An autopsy case of argyrophilic grain dementia with abundant neurofibrillary tangles].
|
No To Shinkei
|
2003
|
0.75
|