Published in Cell Cycle on February 16, 2010
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell (2004) 10.89
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Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways. Nat Med (2011) 6.21
ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation. Nat Cell Biol (2008) 5.19
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PTEN, PIK3CA, p-AKT, and p-p70S6K status: association with trastuzumab response and survival in patients with HER2-positive metastatic breast cancer. Am J Pathol (2010) 2.52
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14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition. Cancer Cell (2009) 2.09
PI(3)king apart PTEN's role in cancer. Clin Cancer Res (2010) 2.07
Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers. Mol Carcinog (2008) 2.01
Genome sequences of three agrobacterium biovars help elucidate the evolution of multichromosome genomes in bacteria. J Bacteriol (2009) 1.96
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PEGylated PLGA nanoparticles for the improved delivery of doxorubicin. Nanomedicine (2009) 1.70
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Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis. Mol Cell (2002) 1.67
Genome sequence of Azotobacter vinelandii, an obligate aerobe specialized to support diverse anaerobic metabolic processes. J Bacteriol (2009) 1.64
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Interruption of enfuvirtide in HIV-1 infected adults with incomplete viral suppression on an enfuvirtide-based regimen. J Infect Dis (2006) 1.62
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Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer. Cancer Res (2010) 1.45
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Endogenous CCL2 neutralization restricts HIV-1 replication in primary human macrophages by inhibiting viral DNA accumulation. Retrovirology (2015) 1.43
The human NBCe1-A mutant R881C, associated with proximal renal tubular acidosis, retains function but is mistargeted in polarized renal epithelia. Am J Physiol Cell Physiol (2006) 1.43
The role of nanometer and sub-micron surface features on vascular and bone cell adhesion on titanium. Biomaterials (2008) 1.43
14-3-3 zeta down-regulates p53 in mammary epithelial cells and confers luminal filling. Cancer Res (2008) 1.41
Mst1 is an interacting protein that mediates PHLPPs' induced apoptosis. Mol Cell (2010) 1.40
Tunable bandgap in silicene and germanene. Nano Lett (2011) 1.39
Hydrothermal syntheses and structural characterizations of organic-inorganic hybrid materials of the M(II)-ligand/vanadium oxide system (M(II) = Mn(II), Cu(II) and Zn(II); ligand = 2,2'-bipyridine and 1,10-phenanthroline). Dalton Trans (2007) 1.38
Tissue transglutaminase promotes drug resistance and invasion by inducing mesenchymal transition in mammary epithelial cells. PLoS One (2010) 1.36
Rad51 overexpression contributes to chemoresistance in human soft tissue sarcoma cells: a role for p53/activator protein 2 transcriptional regulation. Mol Cancer Ther (2007) 1.36
ErbB2 promotes Src synthesis and stability: novel mechanisms of Src activation that confer breast cancer metastasis. Cancer Res (2005) 1.35
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A systems biology understanding of the synergistic effects of arsenic sulfide and Imatinib in BCR/ABL-associated leukemia. Proc Natl Acad Sci U S A (2009) 1.32
Earliest known coelacanth skull extends the range of anatomically modern coelacanths to the Early Devonian. Nat Commun (2012) 1.32
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Fossil fishes from china provide first evidence of dermal pelvic girdles in osteichthyans. PLoS One (2012) 1.30
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Cancer cell stiffness: integrated roles of three-dimensional matrix stiffness and transforming potential. Biophys J (2010) 1.24
The virology and developments toward control of human enterovirus 71. Crit Rev Microbiol (2011) 1.22
Structural mechanism of substrate RNA recruitment in H/ACA RNA-guided pseudouridine synthase. Mol Cell (2009) 1.21
Selective inhibition of ErbB2-overexpressing breast cancer in vivo by a novel TAT-based ErbB2-targeting signal transducers and activators of transcription 3-blocking peptide. Cancer Res (2006) 1.21
Inhibition of nuclear factor-kappaB ameliorates bowel injury and prolongs survival in a neonatal rat model of necrotizing enterocolitis. Pediatr Res (2007) 1.20
14-3-3ζ as a prognostic marker and therapeutic target for cancer. Expert Opin Ther Targets (2010) 1.18
BikDD eliminates breast cancer initiating cells and synergizes with lapatinib for breast cancer treatment. Cancer Cell (2011) 1.17
Tunable and sizable band gap in silicene by surface adsorption. Sci Rep (2012) 1.17
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Mitotic deregulation by survivin in ErbB2-overexpressing breast cancer cells contributes to Taxol resistance. Clin Cancer Res (2009) 1.13
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Isolation and structural elucidation of abietic acid as the main adulterant in an herbal drug for the treatment of psoriasis. J Pharm Biomed Anal (2012) 1.11
Synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest in HER2-overexpressing breast cancer cells. Mol Cancer Ther (2006) 1.10
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PinX1 is a novel microtubule-binding protein essential for accurate chromosome segregation. J Biol Chem (2009) 1.09
ErbB2-mediated Src and signal transducer and activator of transcription 3 activation leads to transcriptional up-regulation of p21Cip1 and chemoresistance in breast cancer cells. Mol Cancer Res (2009) 1.09
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The finished DNA sequence of human chromosome 12. Nature (2006) 1.08
Analysis of Ppp1cc-null mice suggests a role for PP1gamma2 in sperm morphogenesis. Biol Reprod (2007) 1.07
Enhanced sensitization to taxol-induced apoptosis by herceptin pretreatment in ErbB2-overexpressing breast cancer cells. Cancer Res (2002) 1.07
Critical epitopes in the nucleocapsid protein of SFTS virus recognized by a panel of SFTS patients derived human monoclonal antibodies. PLoS One (2012) 1.07
SRC family kinases as novel therapeutic targets to treat breast cancer brain metastases. Cancer Res (2013) 1.06
ErbB2 overexpression correlates with increased expression of vascular endothelial growth factors A, C, and D in human breast carcinoma. Cancer (2002) 1.06
Structural insights into TIR domain specificity of the bridging adaptor Mal in TLR4 signaling. PLoS One (2012) 1.05
Pten regulates Aurora-A and cooperates with Fbxw7 in modulating radiation-induced tumor development. Mol Cancer Res (2012) 1.05
Cancer cell migration: integrated roles of matrix mechanics and transforming potential. PLoS One (2011) 1.05
A zebrafish (Danio rerio) model of infectious spleen and kidney necrosis virus (ISKNV) infection. Virology (2008) 1.04
Mutational analysis of endonuclease V from Thermotoga maritima. Biochemistry (2002) 1.02
Circulation of reassortant influenza A(H7N9) viruses in poultry and humans, Guangdong Province, China, 2013. Emerg Infect Dis (2014) 1.02
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Evidence that aberrant expression of tissue transglutaminase promotes stem cell characteristics in mammary epithelial cells. PLoS One (2011) 1.00
Summary statistics of neonatal intensive care unit network neurobehavioral scale scores from the maternal lifestyle study: a quasinormative sample. Pediatrics (2004) 1.00
Platelet-activating factor induces TLR4 expression in intestinal epithelial cells: implication for the pathogenesis of necrotizing enterocolitis. PLoS One (2010) 1.00
Electronic and Mechanical Coupling in Bent ZnO Nanowires. Adv Mater (2009) 0.99