K N Kreuzer

Author PubWeight™ 81.21‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mechanism of action of nalidixic acid: purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme. Proc Natl Acad Sci U S A 1977 14.75
2 The importance of repairing stalled replication forks. Nature 2000 7.93
3 Escherichia coli mutants thermosensitive for deoxyribonucleic acid gyrase subunit A: effects on deoxyribonucleic acid replication, transcription, and bacteriophage growth. J Bacteriol 1979 4.48
4 Formation and resolution of DNA catenanes by DNA gyrase. Cell 1980 2.68
5 Structure and activities of Escherichia coli DNA gyrase. Cold Spring Harb Symp Quant Biol 1979 2.35
6 Studies on DNA replication in the bacteriophage T4 in vitro system. Cold Spring Harb Symp Quant Biol 1983 2.09
7 Escherichia coli phage T4 topoisomerase. Methods Enzymol 1983 1.71
8 Lambda transducing phages for the nalA gene of Escherichia coli and conditional lethal nalA mutations. Mol Gen Genet 1978 1.54
9 The bacteriophage T4 insertion/substitution vector system. A method for introducing site-specific mutations into the virus chromosome. J Biol Chem 1988 1.49
10 Site-specific recognition of bacteriophage T4 DNA by T4 type II DNA topoisomerase and Escherichia coli DNA gyrase. J Biol Chem 1984 1.49
11 Repair of double-strand breaks in bacteriophage T4 by a mechanism that involves extensive DNA replication. Genetics 1996 1.38
12 Disruption of a topoisomerase-DNA cleavage complex by a DNA helicase. Proc Natl Acad Sci U S A 1994 1.34
13 Bacteriophage T4 UvsW protein is a helicase involved in recombination, repair and the regulation of DNA replication origins. EMBO J 1997 1.28
14 RNA-DNA hybrid formation at a bacteriophage T4 replication origin. J Mol Biol 1997 1.22
15 Deletion analysis of bacteriophage T4 tertiary origins. A promoter sequence is required for a rifampicin-resistant replication origin. J Biol Chem 1988 1.21
16 Hotspot sites for acridine-induced frameshift mutations in bacteriophage T4 correspond to sites of action of the T4 type II topoisomerase. J Mol Biol 1988 1.20
17 A defective phage system reveals bacteriophage T4 replication origins that coincide with recombination hot spots. Proc Natl Acad Sci U S A 1985 1.12
18 Two-dimensional gel analysis of rolling circle replication in the presence and absence of bacteriophage T4 primase. Nucleic Acids Res 1996 1.11
19 Bacteriophage T4 mutants hypersensitive to an antitumor agent that induces topoisomerase-DNA cleavage complexes. Genetics 1996 1.06
20 Localization of an aminoacridine antitumor agent in a type II topoisomerase-DNA complex. Proc Natl Acad Sci U S A 1994 1.06
21 Purified MotA protein binds the -30 region of a bacteriophage T4 middle-mode promoter and activates transcription in vitro. J Biol Chem 1992 1.06
22 Recombination hotspots in bacteriophage T4 are dependent on replication origins. Proc Natl Acad Sci U S A 1991 1.06
23 Repair of topoisomerase-mediated DNA damage in bacteriophage T4. Genetics 2001 1.06
24 Expression and function of the uvsW gene of bacteriophage T4. J Mol Biol 1990 1.06
25 Characterization of a defective phage system for the analysis of bacteriophage T4 DNA replication origins. J Mol Biol 1986 1.04
26 Bacteriophage T4 gene 41 helicase and gene 59 helicase-loading protein: a versatile couple with roles in replication and recombination. Proc Natl Acad Sci U S A 2001 1.03
27 Mutational analysis of a type II topoisomerase cleavage site: distinct requirements for enzyme and inhibitors. EMBO J 1993 1.01
28 UvsW protein regulates bacteriophage T4 origin-dependent replication by unwinding R-loops. Mol Cell Biol 2001 1.00
29 The tight linkage between DNA replication and double-strand break repair in bacteriophage T4. Proc Natl Acad Sci U S A 2001 1.00
30 Plasmid models for bacteriophage T4 DNA replication: requirements for fork proteins. J Virol 1992 1.00
31 An antitumor drug-induced topoisomerase cleavage complex blocks a bacteriophage T4 replication fork in vivo. Mol Cell Biol 2000 0.97
32 Evidence for a common mechanism of action for antitumor and antibacterial agents that inhibit type II DNA topoisomerases. J Biol Chem 1990 0.96
33 The activation domain of the MotA transcription factor from bacteriophage T4. EMBO J 1997 0.96
34 Bacteriophage T4 DNA topoisomerase is the target of antitumor agent 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) in T4-infected Escherichia coli. Proc Natl Acad Sci U S A 1989 0.95
35 Bacteriophage T4 proteins replicate plasmids with a preformed R loop at the T4 ori(uvsY) replication origin in vitro. Mol Cell 2001 0.95
36 Mutational alteration of the breakage/resealing subunit of bacteriophage T4 DNA topoisomerase confers resistance to antitumor agent m-AMSA. Mol Gen Genet 1990 0.93
37 Role of MotA transcription factor in bacteriophage T4 DNA replication. J Mol Biol 1992 0.91
38 Role of recombinational repair in sensitivity to an antitumour agent that inhibits bacteriophage T4 type II DNA topoisomerase. Mol Microbiol 1996 0.91
39 Bacteriophage T4 initiates bidirectional DNA replication through a two-step process. Mol Cell 1998 0.90
40 Identification, cloning, and expression of the Escherichia coli pyrazinamidase and nicotinamidase gene, pncA. Antimicrob Agents Chemother 1996 0.90
41 Double-strand break repair in tandem repeats during bacteriophage T4 infection. Genetics 2000 0.88
42 The specificity of topoisomerase-mediated DNA cleavage defines acridine-induced frameshift specificity within a hotspot in bacteriophage T4. Genetics 1991 0.88
43 Two types of recombination hotspots in bacteriophage T4: one requires DNA damage and a replication origin and the other does not. Genetics 2001 0.87
44 Recognition of single-stranded DNA by the bacteriophage T4-induced type II topoisomerase. J Biol Chem 1984 0.86
45 Deletion of the essential gene 24 from the bacteriophage T4 genome. Gene 1993 0.85
46 The MotA protein from bacteriophage T4 contains two domains. Preliminary structural analysis by X-ray diffraction and nuclear magnetic resonance. J Mol Biol 1993 0.85
47 The MotA transcriptional activator of bacteriophage T4 binds to its specific DNA site as a monomer. Biochemistry 1998 0.81
48 Integration of plasmids into the bacteriophage T4 genome. Genetics 1994 0.81
49 A system of transposon mutagenesis for bacteriophage T4. Mol Microbiol 1992 0.80
50 Mutations of the bacteriophage T4 type II DNA topoisomerase that alter sensitivity to antitumor agent 4'-(9-acridinylamino)methanesulfon-m-anisidide and an antibacterial quinolone. Cancer Res 1998 0.79
51 Substitutions in bacteriophage T4 AsiA and Escherichia coli sigma(70) that suppress T4 motA activation mutations. J Bacteriol 2001 0.79
52 Differentially labeled mutant oligonucleotides for analysis of protein-DNA interactions. Biotechniques 1994 0.78